WERAM Information
Tag | Content | ||||||||||||
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WERAM ID | WERAM-Hos-0237 | ||||||||||||
Ensembl Protein ID | ENSP00000363964.4 | ||||||||||||
Uniprot Accession | P25440; BRD2_HUMAN; A2AAU0; B0S7P0; B1AZT1; O00699; O00700; Q15310; Q5STC9; Q63HQ9; Q658Y7; Q6P3U2; Q969U4 | ||||||||||||
Genbank Protein ID | NP_001106653.1; NP_001186384.1; NP_001186385.1; NP_001278915.1; NP_005095.1 | ||||||||||||
Protein Name | Bromodomain-containing protein 2 | ||||||||||||
Genbank Nucleotide ID | NM_001113182.2; NM_001199455.1; NM_001199456.1; NM_001291986.1; NM_005104.3 | ||||||||||||
Gene Name | BRD2;FSH;RING3;KIAA9001 | ||||||||||||
Ensembl Information | |||||||||||||
Details |
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Status | Reviewed | ||||||||||||
Classification |
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Organism | Homo sapiens | ||||||||||||
NCBI Taxa ID | 9606 | ||||||||||||
Functional Description (View) |
May play a role in spermatogenesis or folliculogenesis (By similarity). Binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling. Regulates transcription of the CCND1 gene. Plays a role in nucleosome assembly. | ||||||||||||
Domain Profile | Ac_Reader Bromodomain BROMO.txt 2 ehevsepFrepvdpq.leipdYydiikePmdLstikerleegnYsspeefvkDvrlifnNakaynenkssv 71 |
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Protein Sequence (Fasta) | MLQNVTPHNK LPGEGNAGLL GLGPEAAAPG KRIRKPSLLY EGFESPTMAS VPALQLTPAN 60 PPPPEVSNPK KPGRVTNQLQ YLHKVVMKAL WKHQFAWPFR QPVDAVKLGL PDYHKIIKQP 120 MDMGTIKRRL ENNYYWAASE CMQDFNTMFT NCYIYNKPTD DIVLMAQTLE KIFLQKVASM 180 PQEEQELVVT IPKNSHKKGA KLAALQGSVT SAHQVPAVSS VSHTALYTPP PEIPTTVLNI 240 PHPSVISSPL LKSLHSAGPP LLAVTAAPPA QPLAKKKGVK RKADTTTPTP TAILAPGSPA 300 SPPGSLEPKA ARLPPMRRES GRPIKPPRKD LPDSQQQHQS SKKGKLSEQL KHCNGILKEL 360 LSKKHAAYAW PFYKPVDASA LGLHDYHDII KHPMDLSTVK RKMENRDYRD AQEFAADVRL 420 MFSNCYKYNP PDHDVVAMAR KLQDVFEFRY AKMPDEPLEP GPLPVSTAMP PGLAKSSSES 480 SSEESSSESS SEEEEEEDEE DEEEEESESS DSEEERAHRL AELQEQLRAV HEQLAALSQG 540 PISKPKRKRE KKEKKKKRKA EKHRGRAGAD EDDKGPRAPR PPQPKKSKKA SGSGGGSAAL 600 GPSGFGPSGG SGTKLPKKAT KTAPPALPTG YDSEEEEESR PMSYDEKRQL SLDINKLPGE 660 KLGRVVHIIQ AREPSLRDSN PEEIEIDFET LKPSTLRELE RYVLSCLRKK PRKPYTIKKP 720 VGKTKEELAL EKKRELEKRL QDVSGQLNST KKPPKKANEK TESSSAQQVA VSRLSASSSS 780 SDSSSSSSSS SSSDTSDSDS G 801 |
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Nucleotide Sequence (Fasta) | GGAGGGGGAG GGCTAGTCTG AGCCGCAGCC GCCGCCTCCT CCGCTCGCCC TCCTCCCTGG 60 CGCTGACCGA TGGACCAGCC GCTCCGTGGG GAGGACTCCG GACCCTGGTG GGGGGGCGGG 120 GGGGTTCTTT CGCCCCCGTG GCGGAGGGCC CCTGAGAGGC GGATACGGGT GTGCCTTTGG 180 GGGTGATGTG GCGTGTGGGG GGAAAGGTCC GAGCTCGCCT GGAGGGGGAG GGTTTTTCCC 240 TTAAGTCATC CCTCCCAGGA CTTGCTTTTT CTGCTCTGAG CCGGACGCCG GAATGGAGTT 300 TGAGGAAGAG ATTCTTCGCT GCTGCTGCCT TACCGCCGAG AACCACCACC CGCCAGGCGT 360 CTTGCGGCCA CACCCCTGGC GGGTTCAGGC AGGCTACGCC CACGCGACCC CTCCCGTTTC 420 CCTGCTTTGG CCAATGGAGG AGCTACGAAT GGCACGACCT GCTCGAGCTT GGCAGTCTCC 480 AGTTGGGCTG TGCATGGAAG CTTGGGAAGA CTTTGTTGGA AGGGGAGGCG GGGAGAGAGT 540 GCTGGAGGCT CTGGGGCGAT GGCTTCCGCA CCTCTTCCAA CCACCCTCTT TCCCTGGAGT 600 CGGCGGACCA CAGCTCAGCC AATTGGCTTG GAGATGTGGC GGGTTGCCAC TTCCCTGTGG 660 GTCTCTGCGG CACTCTTCTG CCTGGTGACT GACACCTTGG AAATGAAGTT TATGACGTCA 720 TCGTTGCGGC TGGCCAATAG AAAAAGCTCC CGCGGAGAGG TGTTCCTTCC CCTTCGACTC 780 AGCTTCTTCA CCCGCGTGAG CGAGCGCGCG CGCGCGGAGG GGGTGGGGAA AAGCTCAAGC 840 AGGGTGGCGC GCATGAGCGG CGAAGCTCCT CCTCCCCGCC TATATATAAA GGGCTGGCGC 900 GGGGCTCGGC GGCGCCATTT CGTGCTGGAG TGGAGCAGCC TCTAGAACGA GCTGGAGGAT 960 TCTGCCTACC GATACAGAGC CTTCGAGTCG TCCGGGGCCG CCATTACAAT CCACCTCCAT 1020 CCGCTTGGAA ATGGCCTTCG TCCCGGCCTA TGACTGGTCC CAGCGGGCAG TACAGACCCC 1080 CTAGAAGCCC CTGGAGCTCC CCTTTTTCGG GCCCCGCCCA ATCCTCGGAG TCTGTCCACC 1140 CCCTCTACTC CGCCCTCAAG AGGATTTCAA AGATGGAGGC GGCGGCTCCC TAAACCACTT 1200 TTCGTGTTCA TCCGCCTCCA TCCGAGATCG AAACGGGACC TCGTCGGCCC CGTAGGGGCC 1260 CGACAAGAAG AGGGAATCCC TGCAGACCAA CAGCGGGCTA TATTGACGAC GGTGTCTGAG 1320 ATCGGGGACC GTCTTTTGAA GAGTCAGTCC CTCCTTAGTT GCCCGCCTCA GCTGAGGCCG 1380 CCGCCATTTT CTTGCTGTCC GCCGTCTGCA GAGCGCGCCA AGCTGCCCGG AGCTCTCCGA 1440 GAGGCCCCAA AGAGACTGCT TTCGTGCCGG CCAGGCAGGG GGTTTGTCGC CTGGAGGCCC 1500 AAGAGGAACG GCCTCCCCCC AACTTAGCGG GTTATGCTGG ACCGGGCGGT GAGGGGAACC 1560 GAGGCCACCC GGACTTTCCG CGGCTGAGGG CAGCGCCGGT TCCTTGCGGT CAAGATGCTG 1620 CAAAACGTGA CTCCCCACAA TAAGCTCCCT GGGGAAGGGA ATGCAGGGTT GCTGGGGCTG 1680 GGCCCAGAAG CAGCAGCACC AGGGAAGAGG ATTCGAAAAC CCTCTCTCTT GTATGAGGGC 1740 TTTGAGAGCC CCACAATGGC TTCGGTGCCT GCTTTGCAAC TTACCCCTGC CAACCCACCA 1800 CCCCCGGAGG TGTCCAATCC CAAAAAGCCA GGACGAGTTA CCAACCAGCT GCAATACCTA 1860 CACAAGGTAG TGATGAAGGC TCTGTGGAAA CATCAGTTCG CATGGCCATT CCGGCAGCCT 1920 GTGGATGCTG TCAAACTGGG TCTACCGGAT TATCACAAAA TTATAAAACA GCCTATGGAC 1980 ATGGGTACTA TTAAGAGGAG ACTTGAAAAC AATTATTATT GGGCTGCTTC AGAGTGTATG 2040 CAAGATTTTA ATACCATGTT CACCAACTGT TACATTTACA ACAAGCCCAC TGATGATATT 2100 GTCCTAATGG CACAAACGCT GGAAAAGATA TTCCTACAGA AGGTTGCATC AATGCCACAA 2160 GAAGAACAAG AGCTGGTAGT GACCATCCCT AAGAACAGCC ACAAGAAGGG GGCCAAGTTG 2220 GCAGCGCTCC AGGGCAGTGT TACCAGTGCC CATCAGGTGC CTGCCGTCTC TTCTGTGTCA 2280 CACACAGCCC TGTATACTCC TCCACCTGAG ATACCTACCA CTGTCCTCAA CATTCCCCAC 2340 CCATCAGTCA TTTCCTCTCC ACTTCTCAAG TCCTTGCACT CTGCTGGACC CCCGCTCCTT 2400 GCTGTTACTG CAGCTCCTCC AGCCCAGCCC CTTGCCAAGA AAAAAGGCGT AAAGCGGAAA 2460 GCAGATACTA CCACCCCTAC ACCTACAGCC ATCTTGGCTC CTGGTTCTCC AGCTAGCCCT 2520 CCTGGGAGTC TTGAGCCTAA GGCAGCACGG CTTCCCCCTA TGCGTAGAGA GAGTGGTCGC 2580 CCCATCAAGC CCCCACGCAA AGACTTGCCT GACTCTCAGC AACAACACCA GAGCTCTAAG 2640 AAAGGAAAGC TTTCAGAACA GTTAAAACAT TGCAATGGCA TTTTGAAGGA GTTACTCTCT 2700 AAGAAGCATG CTGCCTATGC TTGGCCTTTC TATAAACCAG TGGATGCTTC TGCACTTGGC 2760 CTGCATGACT ACCATGACAT CATTAAGCAC CCCATGGACC TCAGCACTGT CAAGCGGAAG 2820 ATGGAGAACC GTGATTACCG GGATGCACAG GAGTTTGCTG CTGATGTACG GCTTATGTTC 2880 TCCAACTGCT ATAAGTACAA TCCCCCAGAT CACGATGTTG TGGCAATGGC ACGAAAGCTA 2940 CAGGATGTAT TTGAGTTCCG TTATGCCAAG ATGCCAGATG AACCACTAGA ACCAGGGCCT 3000 TTACCAGTCT CTACTGCCAT GCCCCCTGGC TTGGCCAAAT CGTCTTCAGA GTCCTCCAGT 3060 GAGGAAAGTA GCAGTGAGAG CTCCTCTGAG GAAGAGGAGG AGGAAGATGA GGAGGACGAG 3120 GAGGAAGAAG AGAGTGAAAG CTCAGACTCA GAGGAAGAAA GGGCTCATCG CTTAGCAGAA 3180 CTACAGGAAC AGCTTCGGGC AGTACATGAA CAACTGGCTG CTCTGTCCCA GGGTCCAATA 3240 TCCAAGCCCA AGAGGAAAAG AGAGAAAAAA GAGAAAAAGA AGAAACGGAA GGCAGAGAAG 3300 CATCGAGGCC GAGCTGGGGC CGATGAAGAT GACAAGGGGC CTAGGGCACC CCGCCCACCT 3360 CAACCTAAGA AGTCCAAGAA AGCAAGTGGC AGTGGGGGTG GCAGTGCTGC TTTAGGCCCT 3420 TCTGGCTTTG GACCTTCTGG AGGAAGTGGC ACCAAGCTCC CCAAAAAGGC CACAAAGACA 3480 GCCCCACCTG CCCTGCCTAC AGGTTATGAT TCAGAGGAGG AGGAAGAGAG CAGGCCCATG 3540 AGTTACGATG AGAAGCGGCA GCTGAGCCTG GACATCAACA AATTACCTGG GGAGAAGCTG 3600 GGCCGAGTTG TGCATATAAT CCAAGCCAGG GAGCCCTCTT TACGTGATTC AAACCCAGAA 3660 GAGATTGAGA TTGATTTTGA AACACTCAAG CCATCCACAC TTAGAGAGCT TGAGCGCTAT 3720 GTCCTTTCCT GCCTACGTAA GAAACCCCGG AAGCCCTACA CCATTAAGAA GCCTGTGGGA 3780 AAGACAAAGG AGGAACTGGC TTTGGAGAAA AAGCGGGAAT TAGAAAAGCG GTTACAAGAT 3840 GTCAGCGGAC AGCTCAATTC TACTAAAAAG CCCCCCAAGA AAGCGAATGA GAAAACAGAG 3900 TCATCCTCTG CACAGCAAGT AGCAGTGTCA CGCCTTAGCG CTTCCAGCTC CAGCTCAGAT 3960 TCCAGCTCCT CCTCTTCCTC GTCGTCGTCT TCAGACACCA GTGATTCAGA CTCAGGCTAA 4020 GGGGTCAGGC CAGATGGGGC AGGAAGGCTC CGCAGGACCG GACCCCTAGA CCACCCTGCC 4080 CCACCTGCCC CTTCCCCCTT TGCTGTGACA CTTCTTCATC TCACCCCCCC CCGCCCCCCT 4140 CTAGGAGAGC TGGCTCTGCA GTGGGGGAGG GATGCAGGGA CATTTACTGA AGGAGGGACA 4200 TGGACAAAAC AACATTGAAT TCCCAGCCCC ATTGGGGAGT GATCTCTTGG ACACAGAGCC 4260 CCCATTCAAA ATGGGGCAGG GCAAGGGTGG GAGTGTGCAA AGCCCTGATC TGGAGTTACC 4320 TGAGGCCACA GCTGCCCTAT TCACTTCTAA GGGCCCTGTT TTGAGATTGT TTGTTCTAAT 4380 TTATTTTAAG CTAGGTAAGG CTGGGGGGAG GGTGGGGCCG TGGTCCCCTC AGCCTCCATG 4440 GGGAGGGAAG AAGGGGGAGC TCTTTTTTTA CGTTGATTTT TTTTTTTCTA CTCTGTTTTC 4500 CCTTTTTCCT TCCGCTCCAT TTGGGGCCCT GGGGGTTTCA GTCATCTCCC CATTTGGTCC 4560 CCTGGACTGT CTTTGTTGAT TCTAACTTGT AAATAAAGAA AATATTATTC AAGTTTTGAG 4620 TTACCTTAAT ATTTGCTTTT GTAGTGTTTC AAAAGGAACA TCATAAGAAT TGTCTTGATA 4680 ATTTTGAGGG AAATATTACT GCAGTGAGAA AAGGCAATAG CTAACCTATA ATTGGATTGT 4740 CTTAATTTTT AAACCAGTAG GCTTTTGCTG TGTTTTTAAT AAAGTAAATA TGACTTTTGT 4800 AAATTGA 4808 |
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Sequence Source | Ensembl | ||||||||||||
Keyword | KW-0002--3D-structure |
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Interpro | IPR001487--Bromodomain |
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PROSITE | |||||||||||||
Pfam | PF17035--BET |
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Gene Ontology | GO:0005737--C:cytoplasm |
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Orthology | |||||||||||||
Created Date | 25-Jun-2016 |