WERAM Information

Tag Content
WERAM ID WERAM-Hos-0109
Ensembl Protein ID ENSP00000361219.4
Uniprot Accession Q9UKN8; TF3C4_HUMAN; Q5VZJ7;
Genbank Protein ID NP_036336.2;
Protein Name TF3C-delta;Transcription factor IIIC 90 kDa subunit;TFIIIC 90 kDa subunit;TFIIIC90;Transcription factor IIIC subunit delta;
Genbank Nucleotide ID NM_012204.3;
Gene Name GTF3C4;KAT12
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000125484.11 ENST00000372146.4 ENSP00000361219.4
Details
Type Family Domain Substrates AA References (PMIDs)
HAT HAT_other H3K9; H3K14; H3K18 K 10523658; 18022374
Status Reviewed
Classification
Type Family E-value Score Start End
HAT HAT_other 0 1639
Organism Homo sapiens
NCBI Taxa ID 9606
Functional Description
(View)		 Essential for RNA polymerase III to make a number of small nuclear and cytoplasmic RNAs, including 5S RNA, tRNA, and adenovirus-associated (VA) RNA of both cellular and viral origin. Has histone acetyltransferase activity (HAT) with unique specificity for free and nucleosomal H3. May cooperate with GTF3C5 in facilitating the recruitment of TFIIIB and RNA polymerase through direct interactions with BRF1, POLR3C and POLR3F. May be localized close to the A box.
Domain Profile
  HAT HAT_other
Query: 1   MNTADQARVGPADDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXFRLMVTRREPAVKL 60
           MNTADQARVGPADD                                FRLMVTRREPAVKL
Sbjct: 1   MNTADQARVGPADDGPAPSGEEEGEGGGEAGGKEPAADAAPGPSAAFRLMVTRREPAVKL 60
Query: 61  QYAVSGLEPLAWSEDHRVSVSTARSIAVLELICDVHNPGQDLVIHRTSVPAPLNSCLLKV 120
           QYAVSGLEPLAWSEDHRVSVSTARSIAVLELICDVHNPGQDLVIHRTSVPAPLNSCLLKV
Sbjct: 61  QYAVSGLEPLAWSEDHRVSVSTARSIAVLELICDVHNPGQDLVIHRTSVPAPLNSCLLKV 120
Query: 121 GSKTEVAECKEKFAASKDPTVSQTFMLDRVFNPEGKALPPMRGFKYTSWSPMGCDANGRC 180
           GSKTEVAECKEKFAASKDPTVSQTFMLDRVFNPEGKALPPMRGFKYTSWSPMGCDANGRC
Sbjct: 121 GSKTEVAECKEKFAASKDPTVSQTFMLDRVFNPEGKALPPMRGFKYTSWSPMGCDANGRC 180
Query: 181 LLAALTMDNRLTIQANLNRLQWVQLVDLTEIYGERLYETSYRLSKNEAPEGNLGDFAEFQ 240
           LLAALTMDNRLTIQANLNRLQWVQLVDLTEIYGERLYETSYRLSKNEAPEGNLGDFAEFQ
Sbjct: 181 LLAALTMDNRLTIQANLNRLQWVQLVDLTEIYGERLYETSYRLSKNEAPEGNLGDFAEFQ 240
Query: 241 RRHSMQTPVRMEWSGICTTQQVKHNNECRDVGSVLLAVLFENGNIAVWQFQLPFVGKESI 300
           RRHSMQTPVRMEWSGICTTQQVKHNNECRDVGSVLLAVLFENGNIAVWQFQLPFVGKESI
Sbjct: 241 RRHSMQTPVRMEWSGICTTQQVKHNNECRDVGSVLLAVLFENGNIAVWQFQLPFVGKESI 300
Query: 301 SSCNTIESGITSPSVLFWWEYEHNNRKMSGLIVGSAFGPIKILPVNLKAVKGYFTLRQPV 360
           SSCNTIESGITSPSVLFWWEYEHNNRKMSGLIVGSAFGPIKILPVNLKAVKGYFTLRQPV
Sbjct: 301 SSCNTIESGITSPSVLFWWEYEHNNRKMSGLIVGSAFGPIKILPVNLKAVKGYFTLRQPV 360
Query: 361 ILWKEMDQLPVHSIKCVPLYHPYQKCSCSLVVAARGSYVFWCLLLISKAGLNVHNSHVTG 420
           ILWKEMDQLPVHSIKCVPLYHPYQKCSCSLVVAARGSYVFWCLLLISKAGLNVHNSHVTG
Sbjct: 361 ILWKEMDQLPVHSIKCVPLYHPYQKCSCSLVVAARGSYVFWCLLLISKAGLNVHNSHVTG 420
Query: 421 LHSLPIVSMTADKQNGTVYTCSSDGKVRQLIPIFTDVALKFEHQLIKLSDVFGSVRTHGI 480
           LHSLPIVSMTADKQNGTVYTCSSDGKVRQLIPIFTDVALKFEHQLIKLSDVFGSVRTHGI
Sbjct: 421 LHSLPIVSMTADKQNGTVYTCSSDGKVRQLIPIFTDVALKFEHQLIKLSDVFGSVRTHGI 480
Query: 481 AVSPCGAYLAIITTEGMINGLHPVNKNYQVQFVTLKTFEEAAAQLLESSVQNLFKQVDLI 540
           AVSPCGAYLAIITTEGMINGLHPVNKNYQVQFVTLKTFEEAAAQLLESSVQNLFKQVDLI
Sbjct: 481 AVSPCGAYLAIITTEGMINGLHPVNKNYQVQFVTLKTFEEAAAQLLESSVQNLFKQVDLI 540
Query: 541 DLVRWKILKDKHIPQFLQEALEKKIESSGVTYFWRFKLFLLRILYQSMQKTPSEALWKPT 600
           DLVRWKILKDKHIPQFLQEALEKKIESSGVTYFWRFKLFLLRILYQSMQKTPSEALWKPT
Sbjct: 541 DLVRWKILKDKHIPQFLQEALEKKIESSGVTYFWRFKLFLLRILYQSMQKTPSEALWKPT 600
Query: 601 HEDSKILLVDSPGMGNADDEQQEEGTSSKQVVKQGLQERSKEGDVEEPTDDSLPTTGDAG 660
           HEDSKILLVDSPGMGNADDEQQEEGTSSKQVVKQGLQERSKEGDVEEPTDDSLPTTGDAG
Sbjct: 601 HEDSKILLVDSPGMGNADDEQQEEGTSSKQVVKQGLQERSKEGDVEEPTDDSLPTTGDAG 660
Query: 661 GREPMEEKLLEIQGKIEAVEMHLTREHMKRVLGEVYLHTWITENTSIPTRGLCNFLMSDE 720
           GREPMEEKLLEIQGKIEAVEMHLTREHMKRVLGEVYLHTWITENTSIPTRGLCNFLMSDE
Sbjct: 661 GREPMEEKLLEIQGKIEAVEMHLTREHMKRVLGEVYLHTWITENTSIPTRGLCNFLMSDE 720
Query: 721 EYDDRTARVLIGHISKKMNKQTFPEHCSLCKEILPFTDRKQAVCSNGHIWLRCFLTYQSC 780
           EYDDRTARVLIGHISKKMNKQTFPEHCSLCKEILPFTDRKQAVCSNGHIWLRCFLTYQSC
Sbjct: 721 EYDDRTARVLIGHISKKMNKQTFPEHCSLCKEILPFTDRKQAVCSNGHIWLRCFLTYQSC 780
Query: 781 QSLIYRRCLLHDSIARHPAPEDPDWIKRLLQSPCPFCDSPVF 822
           QSLIYRRCLLHDSIARHPAPEDPDWIKRLLQSPCPFCDSPVF
Sbjct: 781 QSLIYRRCLLHDSIARHPAPEDPDWIKRLLQSPCPFCDSPVF 822
Protein Sequence
(Fasta)		MNTADQARVG PADDGPAPSG EEEGEGGGEA GGKEPAADAA PGPSAAFRLM VTRREPAVKL 60
QYAVSGLEPL AWSEDHRVSV STARSIAVLE LICDVHNPGQ DLVIHRTSVP APLNSCLLKV 120
GSKTEVAECK EKFAASKDPT VSQTFMLDRV FNPEGKALPP MRGFKYTSWS PMGCDANGRC 180
LLAALTMDNR LTIQANLNRL QWVQLVDLTE IYGERLYETS YRLSKNEAPE GNLGDFAEFQ 240
RRHSMQTPVR MEWSGICTTQ QVKHNNECRD VGSVLLAVLF ENGNIAVWQF QLPFVGKESI 300
SSCNTIESGI TSPSVLFWWE YEHNNRKMSG LIVGSAFGPI KILPVNLKAV KGYFTLRQPV 360
ILWKEMDQLP VHSIKCVPLY HPYQKCSCSL VVAARGSYVF WCLLLISKAG LNVHNSHVTG 420
LHSLPIVSMT ADKQNGTVYT CSSDGKVRQL IPIFTDVALK FEHQLIKLSD VFGSVRTHGI 480
AVSPCGAYLA IITTEGMING LHPVNKNYQV QFVTLKTFEE AAAQLLESSV QNLFKQVDLI 540
DLVRWKILKD KHIPQFLQEA LEKKIESSGV TYFWRFKLFL LRILYQSMQK TPSEALWKPT 600
HEDSKILLVD SPGMGNADDE QQEEGTSSKQ VVKQGLQERS KEGDVEEPTD DSLPTTGDAG 660
GREPMEEKLL EIQGKIEAVE MHLTREHMKR VLGEVYLHTW ITENTSIPTR GLCNFLMSDE 720
EYDDRTARVL IGHISKKMNK QTFPEHCSLC KEILPFTDRK QAVCSNGHIW LRCFLTYQSC 780
QSLIYRRCLL HDSIARHPAP EDPDWIKRLL QSPCPFCDSP VF 822
Nucleotide Sequence
(Fasta)		CTTCCGGGTC CGGAACGGCT CCAGCTGTAC GGACTCGTCC CGAGGGGAGC CGGGGACGGC 60
GGCACCGGGC GGGTAGGGAC AAGACTACCG CGCGTGCCCC CGCCTGGTGG CAGCCCCTCT 120
CTGCGTCCCT CGCGGCCTGG CAAAATTACA TTCGGCCGAG AGTTCACGCT GGGGAAGCTC 180
TCTGAATGCC TCTGAGAAGC GAGATCCGGC GCCATCTCAC CGACGAGCCT CCCCTTTACC 240
GCCCCGTGCG TTTCCTCAGC ACTTTAGGAA CTAAAGCCTG TCTGGGTAGC TCCCTAACAG 300
GCTCTGGAGC TCAATCCCTG GGCAGGGAAA AGGGGGTCCT CGGGGCTCCC CGCTCGCTGT 360
CCTTTTTCTG GACAGGCAGT TCCTTGGCCA CCTGGTAGGG CCGCGTTGCC TGGCAACGGC 420
GGGGTCCTTC TTGGCTCGGC GGCGCTCGGG GCCTGAGGGG AGAAAACCGC CGCGGAGGGC 480
GCTGGGGGTG GCGGCGGCGG TCCGGGAGGT GGTCGCGCGA CTGCGTGGAG CGCCAGGGCG 540
TCCGACCTCT GCACCTGAGA GAAGATGAAC ACGGCCGACC AGGCCCGGGT GGGGCCCGCG 600
GACGACGGGC CTGCGCCGTC TGGGGAGGAG GAGGGAGAGG GGGGCGGCGA GGCGGGCGGG 660
AAGGAGCCAG CAGCGGACGC GGCCCCGGGG CCCAGCGCTG CATTCCGCCT CATGGTGACT 720
CGGCGGGAGC CGGCCGTGAA GCTGCAGTAT GCGGTGAGCG GCCTGGAACC GCTGGCTTGG 780
TCCGAGGACC ACCGCGTGTC TGTGTCCACG GCCCGCAGCA TCGCTGTGCT GGAGCTCATC 840
TGCGACGTGC ACAACCCGGG CCAGGACCTG GTTATCCACC GCACCTCGGT GCCCGCACCG 900
CTCAACAGCT GTCTCCTCAA AGTTGGCTCA AAAACAGAAG TTGCTGAGTG CAAGGAGAAA 960
TTCGCCGCCT CCAAGGACCC CACGGTCAGT CAGACTTTCA TGTTGGATAG GGTGTTCAAC 1020
CCTGAGGGGA AGGCTTTACC ACCAATGAGA GGATTCAAGT ACACCAGCTG GTCTCCCATG 1080
GGTTGCGATG CTAATGGCAG GTGCCTCTTG GCAGCACTGA CCATGGACAA TCGCCTGACC 1140
ATCCAGGCAA ATCTCAACAG ACTGCAGTGG GTCCAGCTGG TTGACCTGAC TGAGATCTAT 1200
GGAGAACGTC TTTATGAGAC CAGTTACAGG CTCTCTAAAA ATGAGGCCCC GGAAGGAAAT 1260
CTCGGGGATT TTGCTGAGTT TCAGAGGAGA CACAGCATGC AGACCCCAGT CAGAATGGAG 1320
TGGTCGGGCA TCTGTACCAC CCAGCAGGTC AAGCATAACA ACGAATGCCG GGACGTTGGC 1380
AGTGTGCTCC TGGCTGTCCT CTTTGAAAAC GGTAATATCG CCGTGTGGCA GTTTCAGCTG 1440
CCGTTTGTAG GAAAAGAATC CATCTCTTCA TGCAACACAA TTGAGTCAGG AATCACCTCT 1500
CCCAGTGTAT TGTTTTGGTG GGAATATGAG CACAATAATC GAAAAATGAG TGGCCTTATT 1560
GTGGGGAGTG CTTTTGGACC CATAAAAATT CTTCCTGTCA ATCTCAAAGC AGTCAAAGGC 1620
TATTTCACTT TAAGGCAGCC TGTTATCTTG TGGAAAGAAA TGGACCAGTT ACCTGTGCAC 1680
AGTATCAAAT GTGTGCCACT TTATCATCCT TACCAGAAGT GTAGTTGCAG CTTAGTAGTG 1740
GCTGCAAGAG GCTCTTATGT ATTTTGGTGT CTTCTTCTGA TCTCCAAAGC AGGGCTGAAT 1800
GTTCACAATT CCCATGTCAC AGGCCTTCAC TCACTGCCAA TTGTCTCCAT GACTGCAGAC 1860
AAACAGAATG GAACAGTCTA TACTTGCTCC AGTGACGGAA AGGTGAGGCA GCTGATTCCC 1920
ATTTTCACAG ATGTTGCATT GAAGTTTGAA CACCAGTTGA TTAAACTCTC AGATGTGTTT 1980
GGCTCAGTGA GGACTCACGG GATAGCAGTG AGCCCCTGCG GTGCATACCT GGCCATCATC 2040
ACCACTGAGG GCATGATCAA CGGCCTCCAC CCTGTTAACA AAAACTACCA GGTCCAATTT 2100
GTTACTCTCA AAACCTTTGA AGAGGCAGCT GCTCAGCTCC TGGAATCTTC AGTTCAAAAC 2160
CTTTTTAAGC AGGTAGATTT AATAGACCTA GTACGCTGGA AGATTTTAAA AGATAAACAT 2220
ATCCCTCAAT TTTTACAAGA AGCTTTGGAA AAAAAGATTG AAAGCAGTGG AGTCACCTAT 2280
TTTTGGCGTT TTAAGCTTTT CCTCCTGAGG ATTTTATATC AGTCAATGCA GAAAACCCCT 2340
TCAGAAGCCT TGTGGAAACC CACCCATGAG GACTCAAAAA TCTTACTAGT GGATTCGCCT 2400
GGGATGGGCA ATGCTGACGA TGAACAGCAG GAAGAAGGCA CTTCTTCCAA ACAGGTGGTG 2460
AAGCAAGGCC TGCAGGAGAG GAGCAAGGAA GGAGATGTAG AGGAGCCCAC TGATGACTCG 2520
CTCCCCACGA CTGGAGATGC TGGAGGCCGT GAGCCAATGG AAGAGAAACT CCTGGAAATC 2580
CAAGGGAAAA TCGAAGCTGT GGAGATGCAC TTGACCAGGG AACACATGAA GCGAGTCTTA 2640
GGAGAAGTGT ATCTGCACAC CTGGATCACA GAAAACACTA GCATCCCCAC CCGCGGACTC 2700
TGTAACTTTT TAATGTCTGA TGAAGAGTAT GATGACAGAA CTGCACGGGT GCTGATTGGA 2760
CATATCTCAA AGAAGATGAA CAAACAGACT TTCCCTGAGC ACTGTAGTTT GTGTAAAGAG 2820
ATCTTGCCAT TCACAGATCG CAAACAGGCA GTCTGTTCCA ATGGCCACAT TTGGCTCCGG 2880
TGCTTCTTAA CCTACCAGTC CTGCCAGAGT TTGATATATA GAAGGTGTTT GCTCCATGAC 2940
AGCATTGCCC GGCATCCAGC TCCAGAAGAT CCCGACTGGA TTAAGAGGTT ACTGCAAAGC 3000
CCCTGCCCTT TCTGTGATTC TCCTGTCTTC TAAATAATCA GTGACGGGAA GATGGAAGGG 3060
CATGATGAAC TCTGCCATAG AAAACTTCCT CCAGCCTGAA GAGAAGGATG CACTGGAGGA 3120
AGCCGGACCC TCACGAGTGG AGAGAAGTCC TTGGTGATTG TAAAGAGGGC CCCTGGAGCT 3180
CATTTCTGAA TCGCACTCTC CATTTCCAGA GACTAAAGGA TGTCCTTTGA AATGGCTGGA 3240
CTCAGAGAGT TGGAGTCGTT TTGAGATGAG CATTAGCCCC AGCTTTGTAA CCAATGAGGA 3300
ACACTTACTT ATTTTTAAGT ATCTTGACAG AAGCAATTTG AACACAGTGT CCCGTCATTT 3360
CTAGAAACAG AATGGTCTCT TCTAGAGAGC TTGGATAAGG ACCTTGCTGG GTTGAGTTAG 3420
GTTTTAATCC TTGCTTTGGT TTGGAACTGC CTTCGGGCTC CAGAACTTAA ATTGCTTGGT 3480
CCGTGGCATC TGATGTACCA ACAGAGATTA AAAGTGTAAA GCAACACATG GGCTGATGTT 3540
TTGTTCTCAG AAAATAGCTG CTGGTCTGCA TCCCTCCATT CTTGTTTTTT ATGCATATGG 3600
AAAACATTTT CCTAAAACTC TATATTCTTA AGTTGAAGCC AAGACTAAAA TTTAATGTGT 3660
CAAATGATCT GGTGACTATT ATAATGAATA ATTGTGACTT ATTTTTCATT CTCTCCTGGG 3720
TCATCAGGTT TCCTGACCCA ACTCCTTAAT CCGTATAAAG ATGTCAAATA CTGTAGTTCA 3780
CCCACGCCAC AGCCCTGCTT CAGACTTAAC TGTGGTAGCC TAGATGAGCT ATTTGTACAC 3840
AGAGGAAAAA AAGATATTTT CCTCTTTTAG TAATAAGACT TTCAGTATTT TTAATGTTGA 3900
CATTTCCAGA TGTTTCATTT AGTATCCAGG GGTCTGTCTG GAGACTTCTA GAGAGGGACA 3960
GCTCAGAAGT GAGACCCTTG AGCTCTGGTG CTGTAAGCTT GTGCAATTAA GTTGAACAGA 4020
GCCTGGGAAT TTCTTTCCTC TGCACAGTCC CTTGATATTT GGAATCCAGG TTCTGCCCCC 4080
AACCCCTACC CACCCAGTGG TCTGTTAAGA TGTCTCAGAT GGGGCTGGGC TTGGTGGCTC 4140
ATGCCTGTAC TCTCAACACT TTGGGAAGCA AAGGCAGGCA GATCACAAGG TCAGGAGTTC 4200
AGCCTAACCA ACATGGTGAA ACCGTGTCTC TACTAAAAAT ACAAAAATTA GCCAGGCGTG 4260
GTGGTGCACA CCTGTAATCC CAGCACTTTG GGAGGCCGAG GCAGACGGGT CACTTGAGGC 4320
CAGGAGTTCG AGACCAGCCT GGGCAATATG GCGAGACTCC GTCTCTACTA CAAATACAAA 4380
AGTTAGCCTG GCATGGTGGC GCATGCCTGT AATCTCAGTT ACTCAGGAGG CTGAGGCAGG 4440
AGCATCACTT CAACCCAGGA GGCAGAAGCT GCAGTCAGCC GAGGTGGCAC CACTGCACTT 4500
CAGCCTGGGC AAGACTGGAG ACTGCCTCAA AAAAAAAAGA AAAAAAATGT TGGTACTTAG 4560
ATGATACCAT GACGGCAACC TCCCCACCCC CACCCCGCAT TGATAGGTAG TGCAGACCAG 4620
CCCTTGGAGG CACTTCTAAA CAGTCTGCTC AGAAATGTTT TCTGTTTCCT ATTCAAATTG 4680
CTGTTTTGTC TCCTATGTTT AATCATGTAT TTGCTATTCT GCTTATTTTT CTCATTTGGT 4740
GGTAATTTCA AGAAGAGCGT TTATCCACTA TTGATTTTCA AGAAAGAAAC CAAGCAGCAT 4800
TGAAATCATG AGTAACAGAA TTCAGAACAT TGTATGGTGG AAGTCATTTG TGTCTGCAGC 4860
TGTTTTTTCA CTTTACAATA AATAAGAGTA AAAATTGAGA TCATGTCAAA AAATTATTGC 4920
AGTTTTAATC ATTATGGCAT AGTTTCACTT CCCCTCCCCC CATTAGAATC AGTGGAGATT 4980
TGTTCTTACT AGGGAATTTT GGACTGCTGC CATTTAAAAC TTAGGTTTTT ATTTAAAGCA 5040
GTTGTGCATT TTTGAGAAAA TGTATTGGGA GTAACTAGAG AGGATCTCCC AAATTTTTTT 5100
GTATGTCTCT CTAGGAGTAA ACATGGCAAC AGTTTTTCTA GAACGTGGAC TCACTGCAGG 5160
GACTGGACCC AATGGCATTG TTAAGACCCT AAAATCTAGC CACCACCTGC CTCCCCCAGG 5220
TTTCCACACA CCCAGTTGGA AGGCCTTTCC CTGCCCTTGT CCCTGTCTCA CACCCATGGA 5280
GGTTAAGCTA CAGAGCTGGG GAAACAGGAG ATTTTGAGTT AATGGCAGCC TCACAAATAG 5340
TGCTTCTGAA TTTCTCTGAG GGTCAGCATA CCTCATGGGA GTGTGTTGCT CAGTGCAACC 5400
TTGGAAAAGT GGGAATGGCA CCAGACGTTT TTCAGGTGCC TCTTGCAATT CAAACTTACA 5460
TCCTCTATAC CGTCCTAAAA TTTGCCTGAT CTTATTTGGT AGATTTCAAG TTGCTTTCAG 5520
CTGTGACCGT AATAACTGTT TCAGGAACTG GAGAAATAGT GGAAGTGCTA TTGCCGCGCT 5580
GCATGTAAAG CACAGGAGCA AAGATTCGAT ACAATTAGAC CCTTTAAGCT ACAACGTGGT 5640
TGCATTTGGG GAGTCTGATA CCCACATAGG TATCACATTT TCTCTGCCTG GGGTTAATTT 5700
GTTCTTATTA TTCTAGGTAA GAAATTGATA GCTTGTTATG CTTGGTACTC ATTCTGAAAT 5760
CCCTGTGTGT CCACCAGGCA GACTTCAAGC AATCTCTACC TACTATTATA TCTGCCAAAA 5820
CTACCAATTA TTTTTCAATG TCAGAAGTTA TTAGAGCCAC TGGCAAAGCT CATGGTTGAA 5880
TATGACATTT TTCTGCTTTT CCCTCTAAGA AGTTTTTGAG AATGTTAATG TTGAAGTATG 5940
CAGGCTGGAC CTACCAGCAA GTTTAACACG TTAATTAGGT TAAAAAGAAT ATTAAAAGGC 6000
AATAATTAAA TATTTCAATT ATTTTGTAAT TATAATGGTA TCAAATAAGA TGCAAAAGAA 6060
GTTGATGCTT ATTGGTGCTT AAGAGAATTA CAATACTGGT TTTATGAGCA TCTTTTCTCT 6120
GCAACAGTTA AACTGCCTCA GAGTTTGTGA ATTGCTGCAA TTCCTGGAAT GGAAACAGGA 6180
ATTAGGGTCA CTGGTTGATT GGCACAGGAT CTTTCCATCG TTTCTGCTCC TGACCTCTCT 6240
CTCTTGCCTT TCCTTCCCCC AGACACCCTC TTGGTTTCCA TTCCTTTAGT TCCCTCTGCT 6300
TTAGAACACA GATTACATGT TGGAAAGAAA AATGGATTAA TGGTAAAATT TCTAAAAGCT 6360
AAATTGTACA GTGGGGTCTC ACTTCCTAGA AGAAACTATT GGTAATATTT CTTTCTAAAG 6420
GTAATAGTAT TAATTGTATC TGGTTTTCTT CAAAACTTAA CTATAATTTC CTTGTCAGGG 6480
TGCTCAGTAG CTCTTGGTTT GACTTTGGGC TAAGGGATGT GAAATTTTAG CTCCTTCCCA 6540
CCACCTGTTT CCCCTCACTC CCACCCCCAG CCAATATTCT TCATAAGCAA AAATTATGGT 6600
TAAGCTAAGC TGAATGGGTT ATATTCAAAG TAAGTACAGA CGGCAAATAG GCAGACAAAT 6660
ACAGGAATGT CTTTACAATT AGCCCACCAT GGACTGTTTT GAGTCTCTGC ATGGTTTCCA 6720
TAATTCATTA TGATGTATCT TTATGCTCTT TCACTGCTCT TCTGTGCGTT GGAGTTTAGC 6780
AATTCAGTGA GACTGGGGAG TGTCTCAAGA ATGGAACCTT TGCCTTCAAG GTTGGGTCAT 6840
CAAAAATCCC TCTAAAGGAT CTAACTGTAA TGAACTGTTT TTATTTTTGC CATTAGTGCA 6900
AGTATCAACT GGCAGCCTCA AACAGCTTTA GACTATGTCT CAGGTCTCTC ATAGTTATAC 6960
TTAGAACTGC TCTTTCTTGA AGCTAAAAGA GGTTTTTGGA GTAAAGATCT GCTTCATGTC 7020
TGCTAGCATG GTATCTGCTG TTCAACCTAG TATAGAGCAT GTGAAATGCA ACTGTCCTTT 7080
AATGGAATTC AGCCAAACTC CAAAAATACT GAGTTGCTTC TAGTTATCTA AAGTAGTACA 7140
GAATCACTAT CCCGATGAAG AAGTGGGGTT TTTCAGAAGA TTGTAAACTC ATTTCCATGG 7200
CACAGATACA AATCATCGTC AGGACTTGTT AGCCAGTCCA TGTCTCATTG ATAGGATGTA 7260
GCCTGCCATC TGCATAGATG GTTTAACATG GTGCTGTTTT TGAAAACTTG CTGTGGAAAT 7320
AAATTTGACA GACGAGTAGT TATTTGTAAA GCTGTCCTAG AAAGAGGTTA ATTCTTTTGG 7380
TATATGAATA TTTCTCCTCC AATCCTTTTA ATTAGGTGGT TCAGCTTATC TTGTATTTTC 7440
TGAGTCATAA CTATACTCTA GGGCCAAGAC CTACTATAAA ATCTGGGGTC CTAACCAGAG 7500
AGTTGTTTAG ATCAATATGA TATGCTTTGC CAACATGATC TAAGAAGGTA TTCATTCTTT 7560
CTGGGTTTGA GAAGAGTTGA CGAAAGTGTA AGATTATACT CTCATGCTAA AATAAGGTAT 7620
AGGCTAAGTG AAATACTGTA AATGGGTTGG TTAGAATTAA AGTTTAGAAC TCTAAATCTT 7680
ATGCTTATTT TTAAAGTAAA AAGTTGCCTC ACTGTCATGA AATCCTGTTA CTTTCATTAA 7740
AAAAAAAAAT CCTGTAAAAT GGTCAAATTG GATAATGTAA GAGATAATGA TGGCTTTGAG 7800
GCATTTCATA CTTTACCAGT TTACATTTGG CTAGCAGACT GGTAAGGTTT AGGGTTCTCT 7860
CCACTAATGG AAAATTAAAT GCTAAACGTC CTAAGAATTA TGTTGTTTTC AAGGCTTTGA 7920
CTCAGATTTG TACTTTGATG TATGAAAGTG AATATCAAAC TTGTTTATAG AAAAGACTAT 7980
ATAGAAAAAT AAGTCTGTGT TGTGTATAGT GATACATGTT TTATGTTTAC CCAATGCCTG 8040
TACTAAATCT TGTGCTTGGC TTTGAATTAT ATATGTGTTT ACCTATGACT TTTTTTTGAA 8100
ATAAACAGAA CAGTCATCTA AAAACATAAG GTTTTGGAAA GGAGATGCTT TTTCAATTCT 8160
TACCATCTGA TTAGGTGGAA TGTTTTATAG ACTTTTGGTG TTGAAAAAAA AAAGTTTGAT 8220
AACAATGCAT TTTGCTTGGA ATACCCCCCA ATCCAGAAAA GTTGGTGACT TCTCTCCATT 8280
GTATATATGT ACATAGTTTT CATTACTAGA TTGTAAGCTC CTCAAGGGCA GGAATTGTTT 8340
TATCTTTGTT GTTCCTGCAG CACCTAATGT AAAGTGCCTT GCACAGGGTA GGTGCTCATG 8400
ACGTGTAGAA TGAGTGAGTA ACTTCCTGCC TCATCAGGAT GAAATGTGGT TCACTTCCCC 8460
TGTGTTCAAC ACTACAAAGC TACTCCTGCC AGAAGAGGGC AGAGTTCTTT CTTGGGTTTG 8520
AACTGGCTTT TTTGGGTTGA ACCAGATCAT CCCACATCCT TAGCACTACT TAACCTTCTT 8580
TTCCTGAAGA TTACATATCA GTGTCCTGCG TTTTTATCTA ATATTAGAGC TGAGGTTCCT 8640
AGGAAAATTT TGAAGTGGGG AAGATTATGG AGAAAATGAA ATGGAAATTT GGGGAGGGTG 8700
GTTTGTCAGT ATAAGGCCCT GTGGGGTAAT CATATTTTAG TTATTACTTG TTAAAAGGGT 8760
AACAGAACCT CTGTTTCTTT ACCAAGTCGC TGGTTGGCCA TTTCTCCAAT TGATGAACTA 8820
CCATTGGTTT TAGCTCTTTC TCATTTGGGA TTCCCCTCAA TTGCTTACAT GATTCTGGTA 8880
CTTAGAGTCT AATAGAGTTG CTGTGAATAT GTAGTGCTGT ACATAATGGC AGTTTTGTAA 8940
ATGTGAGATA ACCTTGAATA TGTTGTGGTT TGTATACAGA GCCATTAGTA TTGTTATTTT 9000
GGCCACTTTT TTATTCAAAA TAAATAACAT AATTATTTGT ATA 9044
Sequence Source Ensembl
Keyword

KW-0007--Acetylation
KW-0012--Acyltransferase
KW-0181--Complete proteome
KW-0903--Direct protein sequencing
KW-0238--DNA-binding
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0804--Transcription
KW-0808--Transferase
--
Interpro

IPR024761--TFIIIC_delta_N
IPR024764--TFIIIC_Znf
IPR017986--WD40_repeat_dom
PROSITE
Pfam

PF12657--TFIIIC_delta
PF12660--zf-TFIIIC
Gene Ontology

GO:0005654--C:nucleoplasm
GO:0000127--C:transcription factor TFIIIC complex
GO:0003677--F:DNA binding
GO:0008047--F:enzyme activator activity
GO:0004402--F:histone acetyltransferase activity
GO:0042791--P:5S class rRNA transcription from RNA polymerase III type 1 promoter
GO:0016573--P:histone acetylation
GO:0043085--P:positive regulation of catalytic activity
GO:0006383--P:transcription from RNA polymerase III promoter
GO:0006384--P:transcription initiation from RNA polymerase III promoter
GO:0006351--P:transcription, DNA-templated
GO:0042797--P:tRNA transcription from RNA polymerase III promoter
Orthology
WERAM ID Ensembl Protein ID Species Identity E-value Score
WERAM-Nol-0144 ENSNLEP00000015670.1 Nomascus leucogenys 100 0.0 1637
WERAM-Paa-0214 ENSPANP00000018814.1 Papio anubis 100 0.0 1635
WERAM-Chs-0181 ENSCSAP00000011065.1 Chlorocebus sabaeus 100 0.0 1634
WERAM-Mam-0081 ENSMMUP00000012973.2 Macaca mulatta 98 0.0 1630
WERAM-Poa-0187 ENSPPYP00000022107.2 Pongo abelii 99 0.0 1618
WERAM-Caj-0193 ENSCJAP00000033601.2 Callithrix jacchus 96 0.0 1603
WERAM-Caf-0206 ENSCAFP00000029457.3 Canis familiaris 96 0.0 1589
WERAM-Otg-0086 ENSOGAP00000006821.2 Otolemur garnettii 96 0.0 1586
WERAM-Cap-0154 ENSCPOP00000012836.2 Cavia porcellus 94 0.0 1580
WERAM-Ict-0051 ENSSTOP00000004474.2 Ictidomys tridecemlineatus 97 0.0 1572
WERAM-Loa-0144 ENSLAFP00000012898.2 Loxodonta africana 95 0.0 1570
WERAM-Mup-0142 ENSMPUP00000012425.1 Mustela putorius furo 95 0.0 1568
WERAM-Gog-0096 ENSGGOP00000008136.2 Gorilla gorilla 97 0.0 1565
WERAM-Prc-0045 ENSPCAP00000004132.1 Procavia capensis 95 0.0 1561
WERAM-Aim-0054 ENSAMEP00000004386.1 Ailuropoda melanoleuca 94 0.0 1560
WERAM-Eqc-0158 ENSECAP00000016787.1 Equus caballus 97 0.0 1554
WERAM-Ran-0235 ENSRNOP00000069275.1 Rattus norvegicus 92 0.0 1552
WERAM-Mum-0141 ENSMUSP00000042265.5 Mus musculus 92 0.0 1552
WERAM-Sus-0038 ENSSSCP00000006140.2 Sus scrofa 93 0.0 1551
WERAM-Ptv-0013 ENSPVAP00000001940.1 Pteropus vampyrus 92 0.0 1543
WERAM-Dan-0162 ENSDNOP00000018237.1 Dasypus novemcinctus 95 0.0 1536
WERAM-Bot-0051 ENSBTAP00000005344.4 Bos taurus 94 0.0 1535
WERAM-Ova-0057 ENSOARP00000006214.1 Ovis aries 93 0.0 1508
WERAM-Mod-0105 ENSMODP00000015717.3 Monodelphis domestica 92 0.0 1497
WERAM-Vip-0047 ENSVPAP00000004214.1 Vicugna pacos 92 0.0 1484
WERAM-Pat-0179 ENSPTRP00000036792.5 Pan troglodytes 100 0.0 1474
WERAM-Gaga-0167 ENSGALP00000041753.1 Gallus gallus 88 0.0 1441
WERAM-Meg-0064 ENSMGAP00000006024.2 Meleagris gallopavo 87 0.0 1436
WERAM-Orc-0084 ENSOCUP00000007559.2 Oryctolagus cuniculus 96 0.0 1429
WERAM-Tag-0074 ENSTGUP00000005330.1 Taeniopygia guttata 86 0.0 1402
WERAM-Ect-0059 ENSETEP00000006428.1 Echinops telfairi 88 0.0 1397
WERAM-Dio-0046 ENSDORP00000004750.1 Dipodomys ordii 94 0.0 1390
WERAM-Tub-0105 ENSTBEP00000011996.1 Tupaia belangeri 85 0.0 1365
WERAM-Anp-0004 ENSAPLP00000000397.1 Anas platyrhynchos 86 0.0 1362
WERAM-Sah-0204 ENSSHAP00000022249.1 Sarcophilus harrisii 91 0.0 1362
WERAM-Ora-0053 ENSOANP00000008018.1 Ornithorhynchus anatinus 87 0.0 1306
WERAM-Myl-0131 ENSMLUP00000010516.2 Myotis lucifugus 93 0.0 1282
WERAM-Tut-0160 ENSTTRP00000013367.1 Tursiops truncatus 89 0.0 1266
WERAM-Fia-0020 ENSFALP00000001535.1 Ficedula albicollis 88 0.0 1260
WERAM-Lac-0076 ENSLACP00000009959.1 Latimeria chalumnae 73 0.0 1237
WERAM-Soa-0054 ENSSARP00000005355.1 Sorex araneus 84 0.0 1203
WERAM-Fec-0163 ENSFCAP00000025535.1 Felis catus 96 0.0 1172
WERAM-Xet-0042 ENSXETP00000013724.2 Xenopus tropicalis 69 0.0 1126
WERAM-Leo-0050 ENSLOCP00000006815.1 Lepisosteus oculatus 67 0.0 1109
WERAM-Asm-0064 ENSAMXP00000007106.1 Astyanax mexicanus 62 0.0 1002
WERAM-Pes-0063 ENSPSIP00000008307.1 Pelodiscus sinensis 88 0.0 923
WERAM-Dar-0157 ENSDARP00000092069.4 Danio rerio 58 0.0 887
WERAM-Gaa-0190 ENSGACP00000023972.1 Gasterosteus aculeatus 53 0.0 853
WERAM-Orn-0158 ENSONIP00000016371.1 Oreochromis niloticus 54 0.0 846
WERAM-Mae-0113 ENSMEUP00000010731.1 Macropus eugenii 90 0.0 842
WERAM-Tar-0065 ENSTRUP00000013163.1 Takifugu rubripes 52 0.0 824
WERAM-Orla-0131 ENSORLP00000015493.1 Oryzias latipes 51 0.0 801
WERAM-Ten-0064 ENSTNIP00000008102.1 Tetraodon nigroviridis 51 0.0 791
WERAM-Xim-0020 ENSXMAP00000001897.1 Xiphophorus maculatus 47 0.0 723
WERAM-Mim-0105 ENSMICP00000009672.1 Microcebus murinus 96 0.0 712
WERAM-Pof-0048 ENSPFOP00000003714.1 Poecilia formosa 49 4e-161 566
WERAM-Ocp-0015 ENSOPRP00000001613.1 Ochotona princeps 90 6e-158 555
WERAM-Gam-0204 ENSGMOP00000019723.1 Gadus morhua 52 1e-154 544
WERAM-Pem-0089 ENSPMAP00000009325.1 Petromyzon marinus 33 1e-55 216
WERAM-Cii-0035 ENSCINP00000013489.3 Ciona intestinalis 22 8e-21 100
Created Date 25-Jun-2016