WERAM Information

Tag Content
WERAM ID WERAM-Nol-0144
Ensembl Protein ID ENSNLEP00000015670.1
Gene Name GTF3C4
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSNLEG00000012911.1 ENSNLET00000016466.1 ENSNLEP00000015670.1
Status Unreviewed
Classification
Type Family E-value Score Start End
HAT HAT_other 0 1637
Organism Nomascus leucogenys
Domain Profile
  HAT HAT_other
Query: 1   MNTADQARVGPADDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXFRLMVTRREPAVKL 60
           MNTADQARVGPADD                                FRLMVTRREPAVKL
Sbjct: 1   MNTADQARVGPADDGPAPSGEEEGEGGGEAGGKEPAADAAPGPSAAFRLMVTRREPAVKL 60
Query: 61  QYAVSGLEPLSWSEDHRVSVSTARSIAVLELICDVHNPGQDLVIHRTSVPAPLNSCLLKV 120
           QYAVSGLEPL+WSEDHRVSVSTARSIAVLELICDVHNPGQDLVIHRTSVPAPLNSCLLKV
Sbjct: 61  QYAVSGLEPLAWSEDHRVSVSTARSIAVLELICDVHNPGQDLVIHRTSVPAPLNSCLLKV 120
Query: 121 GSKTEVAECKEKFAASKDPTVSQTFMLDRVFNPEGKALPPMRGFKYTSWSPMGCDANGRC 180
           GSKTEVAECKEKFAASKDPTVSQTFMLDRVFNPEGKALPPMRGFKYTSWSPMGCDANGRC
Sbjct: 121 GSKTEVAECKEKFAASKDPTVSQTFMLDRVFNPEGKALPPMRGFKYTSWSPMGCDANGRC 180
Query: 181 LLAALTMDNRLTIQANLNRLQWVQLVDLTEIYGERLYETSYRLSKNEAPEGNLGDFAEFQ 240
           LLAALTMDNRLTIQANLNRLQWVQLVDLTEIYGERLYETSYRLSKNEAPEGNLGDFAEFQ
Sbjct: 181 LLAALTMDNRLTIQANLNRLQWVQLVDLTEIYGERLYETSYRLSKNEAPEGNLGDFAEFQ 240
Query: 241 RRHSMQTPVRMEWSGICTTQQVKHNNECRDVGSVLLAVLFENGNIAVWQFQLPFVGKESI 300
           RRHSMQTPVRMEWSGICTTQQVKHNNECRDVGSVLLAVLFENGNIAVWQFQLPFVGKESI
Sbjct: 241 RRHSMQTPVRMEWSGICTTQQVKHNNECRDVGSVLLAVLFENGNIAVWQFQLPFVGKESI 300
Query: 301 SSCNTIESGITSPSVLFWWEYEHNNRKMSGLIVGSAFGPIKILPVNLKAVKGYFTLRQPV 360
           SSCNTIESGITSPSVLFWWEYEHNNRKMSGLIVGSAFGPIKILPVNLKAVKGYFTLRQPV
Sbjct: 301 SSCNTIESGITSPSVLFWWEYEHNNRKMSGLIVGSAFGPIKILPVNLKAVKGYFTLRQPV 360
Query: 361 ILWKEMDQLPVHSIKCVPLYHPYQKCSCSLVVAARGSYVFWCLLLISKAGLNVHNSHVTG 420
           ILWKEMDQLPVHSIKCVPLYHPYQKCSCSLVVAARGSYVFWCLLLISKAGLNVHNSHVTG
Sbjct: 361 ILWKEMDQLPVHSIKCVPLYHPYQKCSCSLVVAARGSYVFWCLLLISKAGLNVHNSHVTG 420
Query: 421 LHSLPIVSMTADKQNGTVYTCSSDGKVRQLIPIFTDVALKFEHQLIKLSDVFGSVRTHGI 480
           LHSLPIVSMTADKQNGTVYTCSSDGKVRQLIPIFTDVALKFEHQLIKLSDVFGSVRTHGI
Sbjct: 421 LHSLPIVSMTADKQNGTVYTCSSDGKVRQLIPIFTDVALKFEHQLIKLSDVFGSVRTHGI 480
Query: 481 AVSPCGAYLAIITTEGMINGLHPVNKNYQVQFVTLKTFEEAAAQLLESSVQNLFKQVDLI 540
           AVSPCGAYLAIITTEGMINGLHPVNKNYQVQFVTLKTFEEAAAQLLESSVQNLFKQVDLI
Sbjct: 481 AVSPCGAYLAIITTEGMINGLHPVNKNYQVQFVTLKTFEEAAAQLLESSVQNLFKQVDLI 540
Query: 541 DLVRWKILKDKHIPQFLQEALEKKIESSGVTYFWRFKLFLLRILYQSMQKTPSEALWKPT 600
           DLVRWKILKDKHIPQFLQEALEKKIESSGVTYFWRFKLFLLRILYQSMQKTPSEALWKPT
Sbjct: 541 DLVRWKILKDKHIPQFLQEALEKKIESSGVTYFWRFKLFLLRILYQSMQKTPSEALWKPT 600
Query: 601 HEDSKILLVDSPGMGNADDEQQEEGTSSKQVVKQGLQERSKEGDVEEPTDDSLPTTGDAG 660
           HEDSKILLVDSPGMGNADDEQQEEGTSSKQVVKQGLQERSKEGDVEEPTDDSLPTTGDAG
Sbjct: 601 HEDSKILLVDSPGMGNADDEQQEEGTSSKQVVKQGLQERSKEGDVEEPTDDSLPTTGDAG 660
Query: 661 GREPMEEKLLEIQGKIEAVEMHLTREHMKRVLGEVYLHTWITENTSIPTRGLCNFLMSDE 720
           GREPMEEKLLEIQGKIEAVEMHLTREHMKRVLGEVYLHTWITENTSIPTRGLCNFLMSDE
Sbjct: 661 GREPMEEKLLEIQGKIEAVEMHLTREHMKRVLGEVYLHTWITENTSIPTRGLCNFLMSDE 720
Query: 721 EYDDRTARVLIGHISKKMNKQTFPEHCSLCKEILPFTDRKQAVCSNGHIWLRCFLTYQSC 780
           EYDDRTARVLIGHISKKMNKQTFPEHCSLCKEILPFTDRKQAVCSNGHIWLRCFLTYQSC
Sbjct: 721 EYDDRTARVLIGHISKKMNKQTFPEHCSLCKEILPFTDRKQAVCSNGHIWLRCFLTYQSC 780
Query: 781 QSLIYRRCLLHDSIARHPAPEDPDWIKRLLQSPCPFCDSPVF 822
           QSLIYRRCLLHDSIARHPAPEDPDWIKRLLQSPCPFCDSPVF
Sbjct: 781 QSLIYRRCLLHDSIARHPAPEDPDWIKRLLQSPCPFCDSPVF 822
Protein Sequence
(Fasta)		MNTADQARVG PADDGPAPSG EEEGEGGGEA GGKEPAADAA PGPSAAFRLM VTRREPAVKL 60
QYAVSGLEPL SWSEDHRVSV STARSIAVLE LICDVHNPGQ DLVIHRTSVP APLNSCLLKV 120
GSKTEVAECK EKFAASKDPT VSQTFMLDRV FNPEGKALPP MRGFKYTSWS PMGCDANGRC 180
LLAALTMDNR LTIQANLNRL QWVQLVDLTE IYGERLYETS YRLSKNEAPE GNLGDFAEFQ 240
RRHSMQTPVR MEWSGICTTQ QVKHNNECRD VGSVLLAVLF ENGNIAVWQF QLPFVGKESI 300
SSCNTIESGI TSPSVLFWWE YEHNNRKMSG LIVGSAFGPI KILPVNLKAV KGYFTLRQPV 360
ILWKEMDQLP VHSIKCVPLY HPYQKCSCSL VVAARGSYVF WCLLLISKAG LNVHNSHVTG 420
LHSLPIVSMT ADKQNGTVYT CSSDGKVRQL IPIFTDVALK FEHQLIKLSD VFGSVRTHGI 480
AVSPCGAYLA IITTEGMING LHPVNKNYQV QFVTLKTFEE AAAQLLESSV QNLFKQVDLI 540
DLVRWKILKD KHIPQFLQEA LEKKIESSGV TYFWRFKLFL LRILYQSMQK TPSEALWKPT 600
HEDSKILLVD SPGMGNADDE QQEEGTSSKQ VVKQGLQERS KEGDVEEPTD DSLPTTGDAG 660
GREPMEEKLL EIQGKIEAVE MHLTREHMKR VLGEVYLHTW ITENTSIPTR GLCNFLMSDE 720
EYDDRTARVL IGHISKKMNK QTFPEHCSLC KEILPFTDRK QAVCSNGHIW LRCFLTYQSC 780
QSLIYRRCLL HDSIARHPAP EDPDWIKRLL QSPCPFCDSP VF 822
Nucleotide Sequence
(Fasta)		GAGCTCAATC CCTGGGCAGG GGAAAGGGGG TCCTCGGGGA TCCCCGCTCG CGGTCCTTTT 60
TCTTGACAGG CAGTTCCTTG GCCACCTGGC AGGGCCGCGT TGCCTGGCAA CGGCGGGGTC 120
CTTCTTGGCT CGGCGGCGCT CGGGGCCTGA GGGGAGAAAA CCGCCGCGGA GGGCGCTGGG 180
GGTGGCGGCG GCGGTCCAGG AGGTGGCCGT GCGACTGCGT GGAGCGCCAG GGCGTCCGAC 240
CTCTGCACCT GAGAGAAGAT GAACACGGCC GACCAGGCCC GGGTGGGGCC CGCGGACGAC 300
GGGCCTGCGC CGTCCGGGGA GGAGGAGGGA GAGGGGGGCG GCGAGGCGGG CGGGAAGGAG 360
CCAGCAGCGG ACGCGGCCCC GGGGCCCAGC GCTGCATTCC GCCTCATGGT GACTCGGCGG 420
GAGCCGGCCG TGAAGCTGCA GTATGCGGTG AGCGGCCTGG AACCGCTGTC TTGGTCCGAG 480
GACCACCGCG TGTCTGTGTC CACGGCCCGC AGCATCGCTG TGCTGGAGCT CATCTGCGAC 540
GTGCACAACC CGGGCCAGGA CCTGGTTATC CACCGCACCT CGGTACCCGC CCCGCTCAAC 600
AGCTGTCTCC TCAAAGTTGG CTCAAAAACA GAAGTTGCTG AGTGCAAGGA GAAATTCGCC 660
GCCTCCAAGG ACCCCACGGT CAGTCAGACT TTCATGTTGG ATAGGGTGTT CAACCCTGAG 720
GGGAAGGCTT TACCACCAAT GAGAGGATTC AAGTACACCA GCTGGTCTCC CATGGGTTGC 780
GATGCTAATG GCAGGTGCCT CTTGGCAGCA CTGACCATGG ACAATCGCCT GACCATCCAG 840
GCAAATCTCA ACAGACTGCA GTGGGTCCAG CTGGTCGACC TGACTGAGAT CTATGGAGAA 900
CGTCTTTATG AGACCAGTTA CAGGCTCTCT AAAAACGAGG CCCCGGAAGG AAATCTCGGG 960
GATTTTGCTG AGTTCCAGAG GAGACACAGC ATGCAGACCC CAGTCAGAAT GGAGTGGTCG 1020
GGCATCTGTA CCACCCAGCA GGTCAAGCAT AACAACGAAT GCCGGGACGT TGGCAGTGTG 1080
CTCCTGGCTG TCCTCTTTGA AAACGGTAAT ATCGCTGTGT GGCAGTTTCA GCTGCCGTTT 1140
GTAGGAAAAG AATCCATCTC TTCATGCAAC ACGATTGAGT CAGGAATCAC CTCTCCCAGT 1200
GTATTGTTTT GGTGGGAATA TGAGCACAAT AATCGAAAAA TGAGTGGCCT TATTGTGGGG 1260
AGTGCTTTTG GACCCATAAA AATTCTTCCT GTCAATCTCA AAGCAGTCAA AGGCTATTTC 1320
ACTTTAAGGC AGCCTGTTAT CTTGTGGAAA GAAATGGACC AGTTACCTGT GCACAGCATC 1380
AAATGTGTGC CACTTTATCA TCCTTACCAG AAGTGTAGTT GCAGCTTAGT AGTGGCTGCA 1440
AGAGGCTCTT ATGTGTTTTG GTGTCTTCTT CTGATCTCCA AAGCAGGGCT GAATGTTCAC 1500
AATTCCCATG TCACAGGCCT TCACTCACTG CCGATTGTCT CCATGACTGC AGACAAACAG 1560
AATGGAACAG TCTATACTTG CTCCAGTGAT GGAAAGGTGA GGCAGCTGAT TCCCATTTTC 1620
ACAGATGTTG CATTGAAGTT TGAACACCAG TTGATTAAAC TCTCAGATGT GTTTGGCTCA 1680
GTGAGGACTC ACGGGATAGC AGTGAGCCCC TGCGGTGCGT ACCTGGCCAT CATTACCACT 1740
GAGGGCATGA TCAATGGCCT CCACCCCGTT AACAAAAACT ACCAGGTCCA GTTTGTTACT 1800
CTCAAAACCT TTGAAGAGGC AGCTGCTCAG CTCCTGGAAT CTTCAGTTCA AAACCTTTTT 1860
AAGCAGGTAG ATTTAATAGA CCTAGTACGC TGGAAGATTT TAAAAGATAA ACATATCCCT 1920
CAATTTTTAC AAGAAGCTTT GGAAAAAAAG ATTGAAAGCA GTGGAGTCAC CTATTTTTGG 1980
CGTTTTAAGC TTTTCCTCCT GAGGATTTTA TATCAGTCAA TGCAGAAAAC CCCTTCAGAA 2040
GCCTTGTGGA AACCCACCCA TGAGGACTCA AAAATCTTAC TAGTGGATTC GCCTGGGATG 2100
GGCAATGCTG ACGATGAGCA GCAGGAAGAA GGCACTTCTT CCAAACAGGT GGTGAAGCAA 2160
GGCCTGCAGG AGAGGAGCAA GGAAGGAGAT GTAGAGGAGC CCACTGATGA CTCGCTCCCC 2220
ACGACTGGAG ATGCTGGAGG CCGTGAGCCA ATGGAAGAGA AACTCCTGGA AATCCAAGGG 2280
AAAATCGAAG CTGTGGAGAT GCACTTGACC AGGGAACACA TGAAGCGAGT CTTAGGAGAA 2340
GTGTATCTGC ACACCTGGAT CACAGAAAAC ACTAGCATCC CCACCCGCGG ACTCTGTAAC 2400
TTTTTAATGT CTGATGAAGA GTATGATGAC AGAACTGCAC GGGTGCTGAT TGGACATATC 2460
TCAAAGAAGA TGAACAAACA GACTTTCCCT GAGCACTGTA GTTTGTGTAA AGAGATCTTG 2520
CCATTCACAG ATCGCAAACA GGCAGTCTGT TCCAATGGCC ACATTTGGCT CCGGTGCTTC 2580
TTAACCTACC AGTCCTGCCA GAGTTTGATA TATAGAAGGT GTTTGCTTCA TGACAGCATT 2640
GCCCGGCATC CAGCTCCAGA AGATCCCGAC TGGATTAAGA GGTTACTACA AAGCCCCTGC 2700
CCTTTCTGTG ATTCTCCTGT CTTCTAAATA ATCAGTGACG GGAAGATGGA AGGGCATGAC 2760
GAACTCTGCT GTAGAAAACT TCCTCCAGCC TGAAGAGAAG GATGCACTGG AGGAAGCCGG 2820
ACCCTCACAA GTGGAGAGAA GTCCTTGGTG ATTGTAAAGA GGGCCCCTGG AGCTCATTTC 2880
TGAAGGGCAC TCTCCATCTC CAGGGACTAA AGGATGTCCT TTGAAATGGC TGGACTCGGA 2940
GAGTTGGAGC CGTTTTGAGA TGAGCATTAG CCTCAGCTTT GTAACCAATG AGGAACACTT 3000
ATTTTTAAGT ATCTTGACAG AAGCAATTTG AACACAATGT CCCATCATTT CTAGAAACAG 3060
AATGGTCTCT TCTAGAGAGC TTGGATAAGG ACCTTGCTGG GTTGAGTTAG GTTTTAATCC 3120
TTGCTTTGGT CTGGAACTGC CTTCGGGCTG CAGAACTTAA ATTGCTTGGT CCGTGGCATC 3180
CGATGTACCA ACAGAGATTA AAAGTGTAAA GCAACACATG GGCTGATGTT TTGTTCTCAG 3240
AAAATAGCTG CTGGTCTGCA TCCCTCCATT CTTGTTTTTT ATGCATATGG AAAACATTTT 3300
CCTAAAACTC TATATTCTTA AGTTGAAGCT AAGACTAAAA TTTAATGTGT CAAATGATCT 3360
GGTGACTATT ATAATGAATA ATTGTGACTT ACTTTTCATT CTCTTCTGTG TCATCAGATT 3420
TCCTGACCCA AGTCCTTAAT CCGTATAAAG ATGTCAAATA CTGTAGTTCA CCCATGCCAC 3480
AGCCCTGCTT CAGACTTAAC TGTGGTAGCC TAGATGAGCT ATTTGTACAC AGAGGAAAAA 3540
AGATATTTTC CTTTTAGTAA TAAGACTTTT AGTATTTTTA ATGTTGACAT TTCCAGATGT 3600
TTCATTTAGT ATTCAGGGTC TGTCTAGAGA CTTCCAGAGA GGGACAGCTC AGAAGTGAGA 3660
CCCTTGAGCT CTGGTGCTGT AAGCTTGTAC AATTCAGTTG AACAGAGCCT GGGAATTTCT 3720
TTCCTCTGCA CAGTCCCTTG ATATTTGGAA TCCAGGTTCT GCCCCCAACC CCTACCCACC 3780
CAGTGGTCTG TTAAGATGTC TCAGATGGGG CTGGGCATGG TAGCTCATGC CTGTAATCCC 3840
AGCACTTTGG GAGGCCAA 3859
Sequence Source Ensembl
Orthology
WERAM ID Ensembl Protein ID Species Identity E-value Score
WERAM-Hos-0109 ENSP00000361219.4 Homo sapiens 100 0.0 1637
WERAM-Paa-0214 ENSPANP00000018814.1 Papio anubis 99 0.0 1634
WERAM-Chs-0181 ENSCSAP00000011065.1 Chlorocebus sabaeus 99 0.0 1633
WERAM-Mam-0081 ENSMMUP00000012973.2 Macaca mulatta 98 0.0 1628
WERAM-Poa-0187 ENSPPYP00000022107.2 Pongo abelii 99 0.0 1618
WERAM-Caj-0193 ENSCJAP00000033601.2 Callithrix jacchus 96 0.0 1601
WERAM-Caf-0206 ENSCAFP00000029457.3 Canis familiaris 96 0.0 1588
WERAM-Otg-0086 ENSOGAP00000006821.2 Otolemur garnettii 96 0.0 1585
WERAM-Cap-0154 ENSCPOP00000012836.2 Cavia porcellus 94 0.0 1580
WERAM-Loa-0144 ENSLAFP00000012898.2 Loxodonta africana 95 0.0 1570
WERAM-Ict-0051 ENSSTOP00000004474.2 Ictidomys tridecemlineatus 96 0.0 1570
WERAM-Mup-0142 ENSMPUP00000012425.1 Mustela putorius furo 95 0.0 1568
WERAM-Gog-0096 ENSGGOP00000008136.2 Gorilla gorilla 97 0.0 1565
WERAM-Prc-0045 ENSPCAP00000004132.1 Procavia capensis 95 0.0 1562
WERAM-Aim-0054 ENSAMEP00000004386.1 Ailuropoda melanoleuca 94 0.0 1560
WERAM-Eqc-0158 ENSECAP00000016787.1 Equus caballus 97 0.0 1554
WERAM-Mum-0141 ENSMUSP00000042265.5 Mus musculus 92 0.0 1553
WERAM-Ran-0235 ENSRNOP00000069275.1 Rattus norvegicus 92 0.0 1553
WERAM-Sus-0038 ENSSSCP00000006140.2 Sus scrofa 92 0.0 1550
WERAM-Ptv-0013 ENSPVAP00000001940.1 Pteropus vampyrus 92 0.0 1543
WERAM-Dan-0162 ENSDNOP00000018237.1 Dasypus novemcinctus 95 0.0 1536
WERAM-Bot-0051 ENSBTAP00000005344.4 Bos taurus 94 0.0 1533
WERAM-Ova-0057 ENSOARP00000006214.1 Ovis aries 92 0.0 1506
WERAM-Mod-0105 ENSMODP00000015717.3 Monodelphis domestica 92 0.0 1498
WERAM-Vip-0047 ENSVPAP00000004214.1 Vicugna pacos 91 0.0 1482
WERAM-Pat-0179 ENSPTRP00000036792.5 Pan troglodytes 100 0.0 1474
WERAM-Gaga-0167 ENSGALP00000041753.1 Gallus gallus 88 0.0 1440
WERAM-Meg-0064 ENSMGAP00000006024.2 Meleagris gallopavo 87 0.0 1434
WERAM-Orc-0084 ENSOCUP00000007559.2 Oryctolagus cuniculus 96 0.0 1429
WERAM-Tag-0074 ENSTGUP00000005330.1 Taeniopygia guttata 86 0.0 1400
WERAM-Ect-0059 ENSETEP00000006428.1 Echinops telfairi 88 0.0 1395
WERAM-Dio-0046 ENSDORP00000004750.1 Dipodomys ordii 94 0.0 1389
WERAM-Tub-0105 ENSTBEP00000011996.1 Tupaia belangeri 85 0.0 1362
WERAM-Anp-0004 ENSAPLP00000000397.1 Anas platyrhynchos 86 0.0 1362
WERAM-Sah-0204 ENSSHAP00000022249.1 Sarcophilus harrisii 91 0.0 1361
WERAM-Ora-0053 ENSOANP00000008018.1 Ornithorhynchus anatinus 87 0.0 1306
WERAM-Myl-0131 ENSMLUP00000010516.2 Myotis lucifugus 93 0.0 1282
WERAM-Tut-0160 ENSTTRP00000013367.1 Tursiops truncatus 89 0.0 1266
WERAM-Fia-0020 ENSFALP00000001535.1 Ficedula albicollis 88 0.0 1260
WERAM-Lac-0076 ENSLACP00000009959.1 Latimeria chalumnae 73 0.0 1236
WERAM-Soa-0054 ENSSARP00000005355.1 Sorex araneus 84 0.0 1203
WERAM-Fec-0163 ENSFCAP00000025535.1 Felis catus 96 0.0 1172
WERAM-Xet-0042 ENSXETP00000013724.2 Xenopus tropicalis 69 0.0 1125
WERAM-Leo-0050 ENSLOCP00000006815.1 Lepisosteus oculatus 67 0.0 1110
WERAM-Asm-0064 ENSAMXP00000007106.1 Astyanax mexicanus 62 0.0 1002
WERAM-Pes-0063 ENSPSIP00000008307.1 Pelodiscus sinensis 88 0.0 923
WERAM-Dar-0157 ENSDARP00000092069.4 Danio rerio 58 0.0 887
WERAM-Gaa-0190 ENSGACP00000023972.1 Gasterosteus aculeatus 52 0.0 852
WERAM-Orn-0158 ENSONIP00000016371.1 Oreochromis niloticus 54 0.0 847
WERAM-Mae-0113 ENSMEUP00000010731.1 Macropus eugenii 90 0.0 841
WERAM-Tar-0065 ENSTRUP00000013163.1 Takifugu rubripes 52 0.0 823
WERAM-Orla-0131 ENSORLP00000015493.1 Oryzias latipes 51 0.0 800
WERAM-Ten-0064 ENSTNIP00000008102.1 Tetraodon nigroviridis 51 0.0 790
WERAM-Xim-0020 ENSXMAP00000001897.1 Xiphophorus maculatus 47 0.0 723
WERAM-Mim-0105 ENSMICP00000009672.1 Microcebus murinus 96 0.0 712
WERAM-Pof-0048 ENSPFOP00000003714.1 Poecilia formosa 49 4e-161 566
WERAM-Ocp-0015 ENSOPRP00000001613.1 Ochotona princeps 90 5e-158 555
WERAM-Gam-0204 ENSGMOP00000019723.1 Gadus morhua 52 1e-154 544
WERAM-Pem-0089 ENSPMAP00000009325.1 Petromyzon marinus 33 1e-55 216
WERAM-Cii-0035 ENSCINP00000013489.3 Ciona intestinalis 22 5e-21 100
Created Date 25-Jun-2016