WERAM Information

Tag Content
WERAM ID WERAM-Cae-0055
Ensembl Protein ID D2021.1
Uniprot Accession Q09519
Genbank Protein ID NP_509450.1;
Protein Name Ubiquitously transcribed TPR on X
Genbank Nucleotide ID NM_077049.4
Gene Name UTX
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
WBGene00017046 D2021.1 D2021.1
Details
Type Family Domain Substrates AA References (PMIDs)
HDM UTX_UTY Jmjc H3K27 K 9851916
Status Reviewed
Classification
Type Family E-value Score Start End
HDM UTX_UTY 1.70e-93 311.3 367 1026
Organism Caenorhabditis elegans
NCBI Taxa ID 6239
Functional Description
(View)
Domain Profile
  HDM UTX_UTY
  UTX.txt  86 lceknnvdyltgswwpvledlyean 110
              +    +++  +++ w  l +lye+n
  D2021.1 367 FICAIELNSTHSAAWTDLGELYEKN 391
              5555567778888899999999887 PP
  UTX.txt    1 kwkkqlkelsklpafvrvisaanllshvghtilgmntvqlymkvpgsrtpghqennnlcsvninigpgdcewfavpeeywgklsdlceknnvdyltgsww 100 
               kw+kq++elsklpaf+r+i+++n+lsh+gh+++gmntv+l+mkvpg+rtp+hq++n+++s+ninigpgdcewfavp+eywgk+++lcekn+vd+ltg++w
  D2021.1  863 KWGKQINELSKLPAFCRLIAGSNMLSHLGHQVHGMNTVKLFMKVPGCRTPAHQDSNHMASININIGPGDCEWFAVPYEYWGKMHKLCEKNGVDLLTGTFW 962 
               8*************************************************************************************************** PP
  UTX.txt  101 pvledlyeanipvyrfiqkpgdlvyvnagtvhwvqaigwcnniawnvgpltakqyklaleryey 164 
               p+++dl++a+ipv+rf+qk+gd+vyv++g++hwvqa+gwcnni+wnv+pl+++q++++l +yey
  D2021.1  963 PIIDDLLDAGIPVHRFTQKAGDMVYVSGGAIHWVQASGWCNNISWNVAPLNFQQLSISLLSYEY 1026
               ***************************************************************8 PP
Protein Sequence
(Fasta)		MDESEPLPEE RHPGNFKKWL ELPLLTNYEL ERIRTLSSLS FDEFHVQNPA DLTYQVRLFF 60
AKARQYLVRY VDEMKSIYKT HKYKTIERRI FYGLAKQCHV VLLANDWTGA LELYQEVLSH 120
HPDLFSHDPS MYFGLGLVYL HFKQWKPAIE AFTRLLYSFP TGMIALQAKV RLGVCYMELE 180
DYNRCINLFK LAVNDSDESV FMPKFTIKYN IALSHENNDE LEIAESEYEN LITELTQHIS 240
FLQSKSNVDQ QQVDLLISVK AACLRQIGWI SYRRSYKDDA NRLDHLKKAQ ENLISAHDTD 300
PRDGQSYYYL GRVYGEHEPS VSGQVAHDAF VNYRFSIDKK EQNADTWCSI GALYQRQNQP 360
IDALQAFICA IELNSTHSAA WTDLGELYEK NAQYQDALEC FKNAMLNNPV APEPIKARVQ 420
FLEKELSMPV PARPSNHASS STFETVIPSL KEAYEQPIPL ELRNRQDAAY ADREAQYDNA 480
FWDLWEDFRT MEHEKPEDME WDVTYPRPME DLEIQVMQLL RANEPALVKA EREVLECLET 540
SEAVFKVIRA QIADKHRPVK NASKKGQTRL RSHTLFISAK VIEYVIPEAV REMPRVTEEM 600
IQNLRDHGHL LESPRCYSFP FLPKISFNDL PDSFSLLSEL YVSMDISAQE IMQMVHRRTQ 660
PNSTYLPVFE EFAKLPEPPR GPVKPIVTDE DVRTALERSE KHPLILKTPI LTVDNRKEAQ 720
SLELQRFLDG STISCIRGLT GCLRLDLSLF STKAVAEIDG NQEIEIRTQY QLPPETNCDH 780
ASQQTWQCVS DPSYTTVNKY AEYQSESFKH TLKGEAEKIK KNVGGTRGPS PKRMKLYKRA 840
SSPPKHLKSI KYGTNIDLSD DTKWGKQINE LSKLPAFCRL IAGSNMLSHL GHQVHGMNTV 900
KLFMKVPGCR TPAHQDSNHM ASININIGPG DCEWFAVPYE YWGKMHKLCE KNGVDLLTGT 960
FWPIIDDLLD AGIPVHRFTQ KAGDMVYVSG GAIHWVQASG WCNNISWNVA PLNFQQLSIS 1020
LLSYEYNKLR RFKSEVPMQL MCWQVAKNVK FTNQLIYNTC KGVLIRSLAF LRMVADYIVS 1080
QKKTIKAHTR TSGEQSHFCM TCECEVFCIL FVKDIGGKFT VFCVYCAKSQ GIEGFIALQQ 1140
FSFTDLYSIY DNMKYIPAAN NNKMSFTA 1168
Nucleotide Sequence
(Fasta)		ATTTGTATAA TTCCCAAAAA GTCTTGTGCA TGAACACCGT ATCGCTTCTC ACACCGCCAA 60
TGGACGAATC AGAACCTCTG CCGGAGGAGC GTCATCCTGG AAACTTTAAA AAATGGCTGG 120
AACTGCCCCT TCTGACAAAT TATGAACTGG AAAGGATTCG CACATTAAGC AGTTTATCAT 180
TCGACGAGTT TCACGTTCAA AACCCAGCCG ATCTCACTTA TCAAGTCAGA TTGTTCTTTG 240
CAAAAGCCCG CCAATACCTT GTCAGATATG TGGATGAGAT GAAGAGCATT TATAAAACGC 300
ACAAGTACAA GACAATCGAA CGGCGCATTT TCTACGGATT GGCGAAACAG TGTCACGTTG 360
TTCTTTTGGC AAATGATTGG ACCGGAGCAC TGGAGCTTTA TCAAGAAGTG TTGAGCCATC 420
ATCCTGACCT ATTCTCACAT GATCCTTCGA TGTACTTCGG GTTAGGTCTT GTCTACTTGC 480
ATTTCAAACA GTGGAAACCT GCAATCGAGG CATTCACAAG ACTGCTATAT AGTTTTCCAA 540
CCGGTATGAT CGCATTGCAA GCAAAAGTTC GTCTTGGAGT GTGTTACATG GAACTTGAAG 600
ATTACAACAG ATGCATAAAT CTGTTCAAAC TTGCCGTCAA CGACAGTGAT GAGTCAGTAT 660
TTATGCCGAA ATTCACAATT AAGTACAACA TTGCTCTGAG CCACGAGAAT AATGATGAGC 720
TTGAAATTGC AGAATCAGAA TATGAAAACC TAATAACTGA ATTAACACAA CACATCAGTT 780
TCTTACAAAG CAAGTCGAAT GTGGATCAAC AACAAGTTGA CTTATTGATA AGTGTGAAAG 840
CAGCATGTTT GCGACAAATT GGCTGGATTT CATATCGCCG CTCTTATAAA GACGATGCAA 900
ATCGTCTGGA TCATTTGAAG AAGGCCCAAG AGAATCTCAT TAGTGCACAT GATACAGATC 960
CACGAGATGG ACAAAGCTAC TACTATCTGG GACGAGTCTA CGGGGAACAC GAGCCTAGTG 1020
TTAGTGGACA AGTGGCACAC GATGCGTTTG TCAACTACCG GTTTTCGATT GACAAAAAAG 1080
AGCAGAATGC GGACACGTGG TGCTCAATTG GAGCTCTGTA TCAGCGACAA AATCAACCCA 1140
TTGATGCTCT TCAGGCATTC ATATGTGCAA TTGAGCTGAA TTCAACACAT TCTGCGGCAT 1200
GGACAGATCT CGGAGAGCTT TATGAGAAAA ATGCCCAGTA CCAAGATGCG CTGGAGTGTT 1260
TCAAAAATGC AATGCTGAAC AATCCAGTTG CTCCGGAACC AATCAAAGCT CGTGTACAAT 1320
TTCTTGAAAA AGAACTCTCG ATGCCTGTGC CCGCACGTCC CTCAAATCAC GCCTCGTCAT 1380
CAACATTTGA AACCGTGATA CCTTCATTGA AAGAAGCTTA TGAGCAGCCA ATACCTCTAG 1440
AGCTTCGTAA TCGTCAAGAC GCTGCCTATG CTGACAGAGA AGCTCAGTAT GACAACGCGT 1500
TTTGGGATCT TTGGGAAGAT TTCAGAACAA TGGAGCATGA AAAGCCGGAA GATATGGAAT 1560
GGGATGTAAC GTATCCAAGG CCAATGGAAG ATCTCGAAAT CCAGGTTATG CAGTTGCTTC 1620
GTGCCAACGA ACCAGCTTTA GTAAAAGCTG AGAGAGAAGT TCTTGAGTGT TTGGAAACCA 1680
GCGAGGCAGT GTTTAAGGTA ATAAGAGCTC AAATAGCTGA CAAACACAGG CCAGTGAAAA 1740
ATGCGAGCAA AAAAGGCCAA ACACGGCTTA GAAGTCATAC TCTTTTCATT AGTGCAAAAG 1800
TTATTGAATA CGTAATTCCG GAAGCCGTTC GTGAAATGCC ACGTGTCACC GAGGAAATGA 1860
TCCAAAACCT TCGCGACCAT GGGCATCTAC TTGAATCGCC GAGATGCTAC AGCTTCCCAT 1920
TCTTACCGAA AATTTCGTTT AATGACCTTC CGGATAGTTT CAGTTTGCTC TCGGAGCTCT 1980
ATGTTTCAAT GGATATCAGC GCTCAGGAAA TTATGCAAAT GGTTCATAGA AGAACTCAGC 2040
CAAACTCCAC ATACCTACCA GTGTTTGAAG AATTTGCGAA GTTACCCGAG CCACCACGAG 2100
GTCCCGTAAA GCCAATTGTA ACAGATGAAG ATGTACGCAC GGCGCTAGAA AGGAGTGAAA 2160
AGCATCCATT AATTCTTAAA ACCCCAATTC TTACGGTGGA CAATAGGAAG GAAGCTCAAA 2220
GTCTGGAATT ACAACGGTTT TTGGATGGGT CTACTATTTC TTGTATTCGT GGACTTACTG 2280
GTTGCCTTCG CCTCGATTTG TCGCTATTCT CCACGAAAGC AGTGGCAGAA ATTGACGGAA 2340
ACCAAGAAAT TGAAATCCGA ACTCAGTATC AACTACCACC AGAAACGAAC TGTGATCATG 2400
CAAGTCAACA GACATGGCAA TGTGTCAGTG ATCCCTCGTA CACAACAGTC AACAAGTATG 2460
CCGAGTATCA ATCGGAATCG TTCAAGCACA CGCTAAAGGG TGAAGCTGAG AAAATCAAGA 2520
AAAATGTGGG AGGAACACGT GGACCTTCTC CTAAAAGAAT GAAATTGTAT AAGCGAGCCA 2580
GCTCTCCACC GAAACATCTG AAGTCTATTA AATATGGAAC TAATATTGAT TTATCTGATG 2640
ACACTAAATG GGGAAAACAG ATCAACGAAC TTTCTAAACT TCCTGCTTTT TGTCGCCTCA 2700
TCGCCGGCTC AAACATGCTC TCCCACTTGG GGCACCAAGT TCACGGCATG AATACTGTTA 2760
AGCTTTTCAT GAAAGTTCCT GGCTGCAGAA CACCAGCTCA TCAGGATAGC AATCACATGG 2820
CTTCCATCAA CATAAACATT GGTCCCGGTG ACTGTGAATG GTTTGCCGTT CCATACGAGT 2880
ATTGGGGAAA GATGCATAAG TTGTGCGAGA AGAATGGCGT TGATCTTTTG ACTGGAACAT 2940
TTTGGCCTAT TATCGATGAC TTATTAGATG CAGGAATTCC AGTGCACCGT TTCACACAGA 3000
AGGCTGGAGA CATGGTATAT GTGAGTGGCG GAGCCATTCA TTGGGTACAA GCTTCGGGAT 3060
GGTGCAACAA CATTTCTTGG AATGTGGCGC CACTCAACTT TCAACAGTTG AGCATCTCTT 3120
TGCTCAGCTA CGAATACAAC AAGCTGCGCC GATTTAAGAG TGAAGTTCCA ATGCAATTAA 3180
TGTGCTGGCA AGTAGCAAAG AATGTCAAGT TTACCAACCA GCTCATCTAC AATACTTGCA 3240
AAGGTGTATT GATTAGATCA CTTGCATTCC TGAGAATGGT TGCCGATTAT ATCGTGTCTC 3300
AGAAGAAAAC CATAAAAGCT CATACTCGAA CAAGTGGAGA ACAATCCCAT TTCTGTATGA 3360
CGTGCGAGTG TGAAGTGTTT TGTATTTTGT TCGTGAAGGA TATTGGCGGA AAGTTTACAG 3420
TCTTCTGTGT ATACTGTGCT AAATCGCAAG GAATCGAAGG CTTCATAGCT CTTCAGCAGT 3480
TCTCGTTCAC CGACTTGTAC TCAATCTACG ACAACATGAA ATATATACCC GCAGCTAACA 3540
ACAATAAGAT GAGTTTCACT GCCTAGAAAG TTCTAGTTAG GACGTTTTAA TCATTGCATA 3600
TTTTATTTCA CAAACCTGTT CCACTTGATG TGCCTCTCTC CCTCACCCCA AACATTTCCC 3660
CGTTTCAATT TTTGGCGAAA GCTCAAAAGG TCTCGTTCAC TTATCTCAAT CTTCTCAATT 3720
AGTTCATTTG TGTCCCTCTT TCGATACACT TCCAAAACTG TGAAAACCCA AATTTTAAAC 3780
TATTTCCTCA ATTTATCTGA TCTCCTGTTT ATTGTTGAAC TTTTTTTTCA AACTGACTGC 3840
CATGTTTTAC AAAACGTGGG ATTGTTAGCT CATGGATTGT TTTTTTATTT CGAGCTTTAA 3900
TTTTTTCTAA ATAAACTGTT GTTTTGATAA A 3932
Sequence Source Ensembl
Keyword

--
Interpro

IPR003347-- JmjC_dom
IPR013026-- TPR-contain_dom
IPR011990-- TPR-like_helical_dom
IPR019734-- TPR_repeat
PROSITE

PS51184-- JMJC; 1
PS50005-- TPR; 4
PS50293-- TPR_REGION; 2
Pfam

PF02373-- JmjC; 1
PF13414-- TPR_11; 1
PF13174-- TPR_6; 1
Gene Ontology

GO:0071558-- F:histone demethylase activity (H3-K27 specific); IDA:WormBase
GO:0071557-- P:histone H3-K27 demethylation; IDA:WormBase
Orthology
WERAM ID Ensembl Protein ID Species Identity E-value Score
WERAM-Drm-0090 FBpp0079664 Drosophila melanogaster 43 3e-117 421
WERAM-Leo-0012 ENSLOCP00000002191.1 Lepisosteus oculatus 44 3e-117 421
WERAM-Nol-0027 ENSNLEP00000003398.1 Nomascus leucogenys 43 9e-117 419
WERAM-Dar-0142 ENSDARP00000082902.5 Danio rerio 43 1e-116 419
WERAM-Mod-0190 ENSMODP00000026365.3 Monodelphis domestica 43 2e-116 418
WERAM-Lac-0046 ENSLACP00000006800.1 Latimeria chalumnae 43 3e-116 417
WERAM-Orc-0144 ENSOCUP00000012682.3 Oryctolagus cuniculus 43 7e-116 416
WERAM-Mum-0148 ENSMUSP00000045862.6 Mus musculus 43 7e-116 416
WERAM-Tag-0092 ENSTGUP00000006298.1 Taeniopygia guttata 43 7e-116 416
WERAM-Anp-0094 ENSAPLP00000010853.1 Anas platyrhynchos 43 1e-115 416
WERAM-Caf-0151 ENSCAFP00000021559.4 Canis familiaris 43 1e-115 416
WERAM-Pat-0183 ENSPTRP00000037456.5 Pan troglodytes 43 1e-115 416
WERAM-Hos-0151 ENSP00000367203.4 Homo sapiens 43 1e-115 416
WERAM-Mam-0026 ENSMMUP00000004425.2 Macaca mulatta 43 1e-115 416
WERAM-Paa-0055 ENSPANP00000002155.1 Papio anubis 43 1e-115 415
WERAM-Chs-0171 ENSCSAP00000010028.1 Chlorocebus sabaeus 43 1e-115 415
WERAM-Gog-0077 ENSGGOP00000006480.2 Gorilla gorilla 43 1e-115 415
WERAM-Ora-0070 ENSOANP00000010350.2 Ornithorhynchus anatinus 43 1e-115 415
WERAM-Sus-0086 ENSSSCP00000013049.2 Sus scrofa 43 1e-115 415
WERAM-Mup-0146 ENSMPUP00000012827.1 Mustela putorius furo 43 2e-115 415
WERAM-Fia-0019 ENSFALP00000001531.1 Ficedula albicollis 43 3e-115 414
WERAM-Asm-0145 ENSAMXP00000013783.1 Astyanax mexicanus 44 3e-115 414
WERAM-Gaga-0147 ENSGALP00000026095.3 Gallus gallus 43 3e-115 414
WERAM-Sah-0181 ENSSHAP00000019619.1 Sarcophilus harrisii 43 4e-115 414
WERAM-Caj-0114 ENSCJAP00000020276.1 Callithrix jacchus 43 4e-115 413
WERAM-Loa-0137 ENSLAFP00000012409.3 Loxodonta africana 43 5e-115 413
WERAM-Dan-0148 ENSDNOP00000019265.1 Dasypus novemcinctus 43 1e-114 412
WERAM-Eqc-0037 ENSECAP00000006528.1 Equus caballus 43 1e-114 412
WERAM-Orla-0140 ENSORLP00000016899.1 Oryzias latipes 44 1e-114 412
WERAM-Cii-0043 ENSCINP00000023576.2 Ciona intestinalis 39 2e-114 411
WERAM-Fec-0103 ENSFCAP00000008761.3 Felis catus 43 2e-114 411
WERAM-Ova-0032 ENSOARP00000004275.1 Ovis aries 43 3e-114 410
WERAM-Gam-0072 ENSGMOP00000007617.1 Gadus morhua 44 3e-114 410
WERAM-Ict-0022 ENSSTOP00000001438.2 Ictidomys tridecemlineatus 43 3e-114 410
WERAM-Tut-0077 ENSTTRP00000006394.1 Tursiops truncatus 43 4e-114 410
WERAM-Myl-0016 ENSMLUP00000001587.2 Myotis lucifugus 43 4e-114 410
WERAM-Otg-0165 ENSOGAP00000013915.2 Otolemur garnettii 43 5e-114 410
WERAM-Cap-0157 ENSCPOP00000013041.2 Cavia porcellus 43 6e-114 410
WERAM-Gaa-0095 ENSGACP00000012288.1 Gasterosteus aculeatus 44 7e-114 409
WERAM-Ran-0230 ENSRNOP00000073763.1 Rattus norvegicus 42 8e-114 409
WERAM-Tar-0130 ENSTRUP00000028532.1 Takifugu rubripes 43 9e-114 409
WERAM-Aim-0069 ENSAMEP00000006135.1 Ailuropoda melanoleuca 43 1e-113 409
WERAM-Orn-0197 ENSONIP00000020522.1 Oreochromis niloticus 44 1e-113 408
WERAM-Bot-0217 ENSBTAP00000056061.1 Bos taurus 42 8e-113 406
WERAM-Ten-0176 ENSTNIP00000017565.1 Tetraodon nigroviridis 43 1e-112 405
WERAM-Poa-0211 ENSPPYP00000023681.1 Pongo abelii 42 3e-112 404
WERAM-Pof-0084 ENSPFOP00000008526.2 Poecilia formosa 44 5e-112 403
WERAM-Xim-0077 ENSXMAP00000007121.1 Xiphophorus maculatus 43 7e-112 403
WERAM-Xet-0034 ENSXETP00000010467.3 Xenopus tropicalis 42 7e-112 402
WERAM-Anc-0039 ENSACAP00000004438.2 Anolis carolinensis 42 9e-111 399
WERAM-Prc-0139 ENSPCAP00000012640.1 Procavia capensis 42 1e-110 399
WERAM-Dio-0094 ENSDORP00000009558.1 Dipodomys ordii 42 1e-110 399
WERAM-Ocp-0085 ENSOPRP00000007644.1 Ochotona princeps 42 5e-110 397
WERAM-Tub-0075 ENSTBEP00000009338.1 Tupaia belangeri 42 1e-109 395
WERAM-Mim-0136 ENSMICP00000013798.1 Microcebus murinus 42 4e-107 387
WERAM-Ptv-0175 ENSPVAP00000015419.1 Pteropus vampyrus 42 5e-107 387
WERAM-Soa-0034 ENSSARP00000003229.1 Sorex araneus 40 8e-103 372
WERAM-Vip-0032 ENSVPAP00000002998.1 Vicugna pacos 40 9e-101 366
WERAM-Meg-0148 ENSMGAP00000015468.2 Meleagris gallopavo 46 2e-98 358
WERAM-Ere-0131 ENSEEUP00000013778.1 Erinaceus europaeus 46 1e-95 349
WERAM-Cis-0015 ENSCSAVP00000002905.1 Ciona savignyi 45 9e-92 336
WERAM-Pes-0096 ENSPSIP00000011716.1 Pelodiscus sinensis 37 2e-89 328
WERAM-Ect-0058 ENSETEP00000006399.1 Echinops telfairi 46 2e-87 322
Created Date 25-Jun-2016