WERAM Information

Tag Content
WERAM ID WERAM-Art-0111
Ensembl Protein ID AT4G37280.1
Uniprot Accession Q94C32; MRG1_ARATH; O23159
Genbank Protein ID NP_568021.1
Protein Name Protein MRG1
Genbank Nucleotide ID NM_119891.3
Gene Name MRG1;At4g37280;C7A10.80
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
AT4G37280 AT4G37280.1 AT4G37280.1
Details
Type Family Domain Substrates AA References (PMIDs)
Me_Reader Chromodomain Chromo H3K4me3; H3K36me3 K 25855537
Status Reviewed
Classification
Type Family E-value Score Start End
Me_Reader Chromodomain 1.10e-19 71 38 290
Organism Arabidopsis thaliana
NCBI Taxa ID 3702
Functional Description
(View)		 Chromatin remodeling factor. Acts as a 'reader' protein by binding to H3K36me3 and H3K36me3 to control histone H4 acetylation. Increases the transcriptional levels of the flowering time genes FLC and FT (PubMed:25183522, PubMed:25211338). Binds the chromatin at the FT promoter upon interaction with CO (Probable).
Domain Profile
  Me_Reader Chromodomain
  Chromodomain.txt  1 Feverivd....kkelrkgeveYlVrWkGynksddtWepeenLlckelleefekkkekkkkqg 59
                      + ++r+++    k+elrk+e++Y+V+++G+nk++d+W+++++Ll k+++e+++k+k+ +kkqg
       AT4G37280.1 38 YHGPRVYGakvqKVELRKKEWKYFVHYLGWNKNWDEWVSADRLL-KHTEENLVKQKALDKKQG 99
                      568999999999********************************.****************98 PP
  Chromodomain.txt  29 sddtWepeenLlckelle 46 
                       +++tW + ++ l + +l+
       AT4G37280.1 274 EEETWSRMQQTL-SDFLK 290
                       678999887766.45554 PP
Protein Sequence
(Fasta)		MGSSSKEETA SDGDTASGGA SPSNDGRLFS EGERVLAYHG PRVYGAKVQK VELRKKEWKY 60
FVHYLGWNKN WDEWVSADRL LKHTEENLVK QKALDKKQGV EKGTKSGRSA QTKTRSSADT 120
KADKDDTKTN AAKGKKRKHE SGNEKDNVTA EKLMKIQIPA SLKKQLTDDW EYIAQKDKVV 180
KLPRSPNVDE ILSKYLEFKT KKDGMVTDSV AEILKGIRSY FDKALPVMLL YKKERRQYQE 240
SIVDDTSPST VYGAEHLLRL FVKLPDLFSY VNMEEETWSR MQQTLSDFLK FIQKNQSTFL 300
LPSAYDSDKV SDGKGKGKDD
Nucleotide Sequence
(Fasta)		ACGGTTAAAG GGGTGCCTTG TGATGTGAAG ATCTTTGCCT CTCGCTCTCG CTTTCGGTGA 60
CAATGGGAAG CTCGTCGAAG GAAGAGACGG CGAGTGACGG AGATACGGCG AGCGGTGGCG 120
CCTCACCGTC CAACGACGGC AGACTCTTCT CGGAGGGCGA GCGTGTTCTC GCTTACCATG 180
GTCCTCGCGT CTACGGAGCC AAGGTTCAAA AGGTCGAGCT TCGGAAAAAG GAGTGGAAAT 240
ACTTTGTGCA CTATCTTGGT TGGAACAAAA ATTGGGATGA ATGGGTTAGT GCGGATAGAT 300
TGTTGAAACA TACCGAGGAG AATCTTGTCA AACAGAAAGC TCTAGACAAA AAGCAAGGAG 360
TTGAAAAAGG TACCAAGTCT GGCCGTTCCG CTCAGACAAA AACTAGAAGC TCTGCAGACA 420
CAAAGGCTGA TAAAGATGAC ACCAAGACCA ATGCTGCAAA AGGGAAGAAA CGAAAGCACG 480
AGTCAGGCAA TGAGAAGGAT AATGTAACGG CGGAGAAGCT AATGAAGATC CAAATTCCCG 540
CATCACTTAA AAAGCAACTC ACTGACGACT GGGAGTATAT TGCGCAGAAG GACAAGGTTG 600
TGAAACTTCC TCGTTCACCT AACGTCGATG AGATATTGTC CAAGTACCTT GAATTCAAAA 660
CCAAGAAGGA TGGAATGGTA ACTGATTCGG TCGCTGAAAT ATTGAAAGGC ATAAGGAGTT 720
ATTTCGACAA GGCATTGCCA GTGATGCTCC TATATAAGAA AGAGAGGCGA CAATACCAAG 780
AATCAATCGT GGATGATACT TCACCTTCAA CTGTTTATGG CGCCGAGCAT TTGCTCCGTC 840
TCTTTGTCAA GTTGCCAGAT CTTTTTTCAT ATGTAAACAT GGAAGAAGAA ACATGGAGTC 900
GCATGCAACA AACATTATCA GACTTCCTCA AGTTTATTCA GAAGAATCAG AGCACTTTCT 960
TGCTACCATC AGCATATGAT TCTGATAAGG TTTCAGATGG TAAAGGCAAA GGAAAAGACG 1020
ACTGACATCT CCAGGAAAAA AATATTGTTG TAATTTAGAA TTCCTTCATT TTTCTGATGA 1080
ATTCATAATT GTAAGATTTG CAGCTGAATA TGAAATATTT TACAGGCCTT TGAAGTTAAC 1140
TATTTGGTTC ATGTAAATTT CTTTAAGTGG TCAATAAAAC ATCCGGAAC
Sequence Source Ensembl
Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
--
Interpro

IPR000953--Chromo/shadow_dom
IPR016197--Chromodomain-like
IPR008676--MRG
IPR026541--MRG_dom
IPR025995--Tudor-knot
PROSITE

PS51640--MRG
Pfam

PF05712--MRG
PF11717--Tudor-knot
Gene Ontology

GO:0000123--C:histone acetyltransferase complex
GO:0006338--P:chromatin remodeling
GO:0016573--P:histone acetylation
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated
Orthology
WERAM ID Ensembl Protein ID Species Identity E-value Score
WERAM-Arl-0141 scaffold_700360.1 Arabidopsis lyrata 97 6e-163 570
WERAM-Brr-0062 Bra011751.1-P Brassica rapa 88 1e-147 519
WERAM-Thc-0003 EOX91556 Theobroma cacao 76 3e-129 458
WERAM-Glm-0225 GLYMA17G18240.2 Glycine max 69 7e-116 414
WERAM-Pot-0089 POPTR_0007s10460.1 Populus trichocarpa 71 1e-115 413
WERAM-Prp-0070 EMJ06657 Prunus persica 63 2e-112 402
WERAM-Sol-0036 Solyc02g092910.2.1 Solanum lycopersicum 67 9e-112 400
WERAM-Mua-0073 GSMUA_Achr4P12960_001 Musa acuminata 65 4e-102 368
WERAM-Sot-0079 PGSC0003DMT400064229 Solanum tuberosum 69 8e-100 360
WERAM-Aet-0017 EMT06876 Aegilops tauschii 47 3e-67 252
WERAM-Gaga-0083 ENSGALP00000032974.3 Gallus gallus 36 2e-47 187
WERAM-Lac-0146 ENSLACP00000016822.1 Latimeria chalumnae 37 2e-47 186
WERAM-Ran-0248 ENSRNOP00000075745.1 Rattus norvegicus 36 3e-47 186
WERAM-Poa-0059 ENSPPYP00000007607.2 Pongo abelii 36 3e-47 186
WERAM-Caj-0017 ENSCJAP00000004116.2 Callithrix jacchus 36 3e-47 186
WERAM-Dar-0092 ENSDARP00000112985.1 Danio rerio 36 6e-47 185
WERAM-Asm-0023 ENSAMXP00000002832.1 Astyanax mexicanus 36 9e-47 184
WERAM-Orc-0185 ENSOCUP00000016187.1 Oryctolagus cuniculus 36 1e-46 184
WERAM-Bot-0105 ENSBTAP00000014581.5 Bos taurus 38 1e-46 184
WERAM-Anc-0150 ENSACAP00000014061.2 Anolis carolinensis 36 1e-46 184
WERAM-Ten-0100 ENSTNIP00000011271.1 Tetraodon nigroviridis 36 2e-46 183
WERAM-Orn-0162 ENSONIP00000016650.1 Oreochromis niloticus 35 2e-46 183
WERAM-Myl-0017 ENSMLUP00000001606.2 Myotis lucifugus 37 2e-46 183
WERAM-Xet-0054 ENSXETP00000017126.3 Xenopus tropicalis 36 2e-46 183
WERAM-Meg-0107 ENSMGAP00000010790.1 Meleagris gallopavo 36 2e-46 183
WERAM-Dan-0023 ENSDNOP00000002194.3 Dasypus novemcinctus 39 2e-46 183
WERAM-Eqc-0042 ENSECAP00000006422.1 Equus caballus 36 6e-46 181
WERAM-Fec-0161 ENSFCAP00000019835.1 Felis catus 36 1e-45 180
WERAM-Gaa-0180 ENSGACP00000022333.1 Gasterosteus aculeatus 35 2e-45 180
WERAM-Pof-0110 ENSPFOP00000009458.2 Poecilia formosa 35 2e-45 179
WERAM-Leo-0142 ENSLOCP00000017293.1 Lepisosteus oculatus 36 3e-45 179
WERAM-Tum-0023 CAZ84135 Tuber melanosporum 40 3e-45 179
WERAM-Xim-0038 ENSXMAP00000003628.1 Xiphophorus maculatus 35 5e-45 178
WERAM-Sah-0200 ENSSHAP00000021731.1 Sarcophilus harrisii 37 7e-45 178
WERAM-Gam-0087 ENSGMOP00000008960.1 Gadus morhua 35 7e-45 178
WERAM-Pes-0161 ENSPSIP00000019260.1 Pelodiscus sinensis 35 4e-44 175
WERAM-Tag-0122 ENSTGUP00000010081.1 Taeniopygia guttata 32 5e-43 172
WERAM-Tar-0185 ENSTRUP00000038533.1 Takifugu rubripes 34 5e-43 172
WERAM-Otg-0218 ENSOGAP00000018835.1 Otolemur garnettii 35 2e-42 170
WERAM-Orla-0021 ENSORLP00000002554.1 Oryzias latipes 32 3e-41 166
WERAM-Mod-0094 ENSMODP00000014403.2 Monodelphis domestica 32 5e-41 165
WERAM-Tut-0191 ENSTTRP00000015743.1 Tursiops truncatus 32 6e-41 165
WERAM-Mum-0212 ENSMUSP00000082346.5 Mus musculus 32 8e-41 164
WERAM-Loa-0095 ENSLAFP00000008255.3 Loxodonta africana 32 8e-41 164
WERAM-Ict-0118 ENSSTOP00000011915.2 Ictidomys tridecemlineatus 32 8e-41 164
WERAM-Mam-0209 ENSMMUP00000030192.2 Macaca mulatta 32 8e-41 164
WERAM-Pat-0055 ENSPTRP00000051331.1 Pan troglodytes 32 8e-41 164
WERAM-Nol-0090 ENSNLEP00000010671.1 Nomascus leucogenys 32 8e-41 164
WERAM-Hos-0222 ENSP00000331310.5 Homo sapiens 32 8e-41 164
WERAM-Gog-0191 ENSGGOP00000016418.2 Gorilla gorilla 32 8e-41 164
WERAM-Sus-0018 ENSSSCP00000001932.2 Sus scrofa 32 8e-41 164
WERAM-Cap-0042 ENSCPOP00000003411.2 Cavia porcellus 32 1e-40 164
WERAM-Ova-0157 ENSOARP00000015639.1 Ovis aries 32 4e-40 162
WERAM-Anp-0039 ENSAPLP00000004318.1 Anas platyrhynchos 32 5e-40 162
WERAM-Cis-0080 ENSCSAVP00000017617.1 Ciona savignyi 36 1e-39 160
WERAM-Caf-0148 ENSCAFP00000020818.3 Canis familiaris 32 2e-39 160
WERAM-Aim-0138 ENSAMEP00000013010.1 Ailuropoda melanoleuca 32 3e-39 159
WERAM-Mup-0177 ENSMPUP00000015319.1 Mustela putorius furo 32 3e-39 159
WERAM-Fia-0071 ENSFALP00000005346.1 Ficedula albicollis 32 3e-39 159
WERAM-Vip-0092 ENSVPAP00000008230.1 Vicugna pacos 32 1e-38 157
WERAM-Asn-0032 CADANIAP00008637 Aspergillus nidulans 35 1e-36 151
WERAM-Asni-0012 CADANGAP00004222 Aspergillus niger 34 2e-36 150
WERAM-Spr-0011 CBQ68343 Sporisorium reilianum 33 6e-36 148
WERAM-Aso-0013 CADAORAP00001673 Aspergillus oryzae 33 1e-35 147
WERAM-Crn-0021 AAW44213 Cryptococcus neoformans 34 2e-35 147
WERAM-Ect-0096 ENSETEP00000011221.1 Echinops telfairi 30 2e-34 143
WERAM-Asfu-0038 CADAFUAP00008363 Aspergillus fumigatus 32 3e-34 142
WERAM-Soa-0045 ENSSARP00000004121.1 Sorex araneus 29 7e-34 141
WERAM-Yal-0008 CAG80821 Yarrowia lipolytica 33 9e-34 141
WERAM-Asc-0018 CADACLAP00004414 Aspergillus clavatus 34 1e-33 141
WERAM-Coi-0009 EAS36116 Coccidioides immitis 31 7e-32 135
WERAM-Asf-0006 CADAFLAP00002044 Aspergillus flavus 29 2e-30 130
WERAM-Ocp-0117 ENSOPRP00000011535.1 Ochotona princeps 30 3e-28 122
WERAM-Sac-0051 YPR023C Saccharomyces cerevisiae 27 4e-26 115
WERAM-Asg-0009 AAS51868 Ashbya gossypii 26 4e-26 115
WERAM-Chh-0066 ENSCHOP00000007156.1 Choloepus hoffmanni 40 6e-26 115
WERAM-Prc-0160 ENSPCAP00000015337.1 Procavia capensis 38 1e-24 111
WERAM-Ere-0064 ENSEEUP00000005345.1 Erinaceus europaeus 38 1e-24 110
WERAM-Tas-0045 ENSTSYP00000004433.1 Tarsius syrichta 38 1e-24 110
WERAM-Mim-0030 ENSMICP00000002766.1 Microcebus murinus 38 1e-24 110
WERAM-Paa-0050 ENSPANP00000004934.1 Papio anubis 38 2e-24 110
WERAM-Tub-0030 ENSTBEP00000003706.1 Tupaia belangeri 38 2e-24 110
WERAM-Ptv-0177 ENSPVAP00000015442.1 Pteropus vampyrus 38 2e-24 110
WERAM-Chs-0006 ENSCSAP00000017681.1 Chlorocebus sabaeus 38 3e-24 109
WERAM-Ora-0118 ENSOANP00000023079.2 Ornithorhynchus anatinus 39 7e-24 108
WERAM-Ved-0026 EGY15805 Verticillium dahliae 32 8e-22 101
WERAM-Drm-0029 FBpp0082579 Drosophila melanogaster 39 9e-22 101
WERAM-Dio-0073 ENSDORP00000007264.1 Dipodomys ordii 39 7e-20 95.1
WERAM-Pem-0072 ENSPMAP00000007740.1 Petromyzon marinus 42 2e-16 84.3
WERAM-Mae-0068 ENSMEUP00000006768.1 Macropus eugenii 32 6e-15 79.0
Created Date 25-Jun-2016