WERAM Information

Tag Content
WERAM ID WERAM-Art-0019
Ensembl Protein ID AT1G54390.4
Uniprot Accession B3H615; ING2_ARATH; Q8L631; Q9SLJ4
Genbank Protein ID NP_564658.2; NP_974026.1; NP_974027.1
Protein Name PHD finger protein ING2
Genbank Nucleotide ID NM_104317.3; NM_202297.2; NM_202298.2
Gene Name ING2
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
AT1G54390 AT1G54390.4 AT1G54390.4
AT1G54390 AT1G54390.3 AT1G54390.3
AT1G54390 AT1G54390.5 AT1G54390.5
AT1G54390 AT1G54390.6 AT1G54390.6
Details
Type Family Domain Substrates AA References (PMIDs)
Me_Reader PHD PHD-type H3K4me3/2 K 19154204
Status Reviewed
Classification
Type Family E-value Score Start End
Me_Reader PHD 5.30e-12 46.5 207 256
Organism Arabidopsis thaliana
NCBI Taxa ID 3702
Functional Description
(View)		 Histone-binding component that specifically recognizes H3 tails trimethylated on 'Lys-4' (H3K4me3), which mark transcription start sites of virtually all active genes.
Domain Profile
  Me_Reader PHD
      PHD.txt   2 tiClvCgkddegekemvqCde..Cd..dwfHlkCvklplsslpegkswyCpsCk 51 
                  t+C+ C+++++g+  m+ Cd+  C+  +wfH++Cv+l+ ++  +g +wyCp+C+
  AT1G54390.4 207 TYCV-CHQVSFGD--MIACDNenCQggEWFHYTCVGLTPETRFKG-KWYCPTCR 256
                  89*9.*******6..********9999***********88888**.*******7 PP
Protein Sequence
(Fasta)		MAIARTGVYV DDYLEYASTF PAELQRLLNT VRELDERSQS LINQTRQQTK YCLGLASQSS 60
KKGNGNHYNN GGLDEEETIE KMRKEIESSQ ENALSLCTEK VLLARQAYDL IDSHVKRLDE 120
DLNNFAEDLK QEGKIPPDEP SVLPPLPIVP KAEKRKSFYG TPQPKKIDYR DRDWDRDRDF 180
ELMPPPGSNR KDLMPIEEQP IDPNEPTYCV CHQVSFGDMI ACDNENCQGG EWFHYTCVGL 240
TPETRFKGKW YCPTCRLLPQ SH 262
Nucleotide Sequence
(Fasta)		AAGCTTCGTT CTCAATCCCA ATTCGAAATC CTAGCTGAAG TCTATGCTCC ATAATCAAAT 60
CCAGTTCATC AGAGATCAAA GATGGCTATT GCACGAACTG GAGTTTATGT TGATGATTAC 120
CTTGAGTATG CAAGCACTTT CCCTGCAGAG CTACAAAGAT TACTAAACAC AGTTCGCGAA 180
CTAGACGAGA GATCTCAATC GCTTATAAAT CAGACAAGAC AGCAAACTAA GTATTGCTTA 240
GGGCTTGCTT CACAGAGTTC TAAAAAGGGT AATGGTAATC ATTACAATAA TGGTGGTCTT 300
GATGAAGAGG AAACGATTGA GAAAATGCGT AAAGAGATTG AGTCTAGTCA GGAAAATGCG 360
TTAAGTTTGT GTACCGAGAA GGTTTTATTG GCCCGACAAG CGTATGATCT TATAGATAGT 420
CATGTAAAAC GACTTGATGA AGATCTGAAT AATTTTGCAG AAGATTTAAA GCAAGAGGGA 480
AAAATTCCAC CAGACGAGCC CTCTGTTCTT CCTCCACTAC CTATAGTTCC TAAAGCGGAA 540
AAGCGTAAGT CCTTCTATGG CACACCTCAG CCCAAGAAGA TTGATTATAG AGATAGAGAC 600
TGGGATCGTG ACAGGGATTT TGAGCTCATG CCTCCTCCAG GAAGCAATCG GAAAGACCTT 660
ATGCCAATTG AAGAGCAGCC AATCGATCCA AACGAACCAA CTTACTGTGT CTGCCATCAG 720
GTGTCCTTTG GAGACATGAT TGCCTGTGAC AATGAGAATT GCCAAGGAGG TGAATGGTTT 780
CACTATACAT GCGTTGGCCT CACACCTGAG ACCAGATTCA AAGGGAAATG GTACTGCCCC 840
ACCTGCAGAC TCCTCCCACA GTCACACTAA TATCATTTGT ACCTGTGAGA AGGTGCCACT 900
GGCATCTTCT TTGGCACCTT CCCTTCATGA CCAATGCCAC CAAACTCATC TTTCTTGTTA 960
CCCAACATCT AGCAAGTGCA AGTAGAAGCA AACTTTAGAT GGAGAAATCA TCATGTTTTG 1020
TAAACCTCGG GTTAATTCGT GGAGCATATA TTTTGTATAT CAATTGTATT TGGGTATTGG 1080
TGGGCATTTT CCGTTTTATT CTACTAGTAT CGATATTTAC ATCTGCTTCT TTCTTTCTTT 1140
TTTCCCCTCA AACCATGAGC CTTTGTATTG ATCAAATGAC ATGTACAAAG GTTTTGTTCA 1200
TCAGAAGGAA TTTCACTAAA ATAAAAAATT GCTTG 1236
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0341--Growth regulation
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger
--
Interpro

IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS50016--ZF_PHD_2
Pfam

PF12998--ING
Gene Ontology

GO:0005634--C:nucleus
GO:0035064--F:methylated histone binding
GO:0008270--F:zinc ion binding
GO:0016568--P:chromatin modification
GO:0040008--P:regulation of growth
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated
Orthology
WERAM ID Ensembl Protein ID Species Identity E-value Score
WERAM-Brr-0205 Bra040776.1-P Brassica rapa 94 3e-125 444
WERAM-Bro-0076 Bo4g134590.1 Brassica oleracea 91 3e-122 434
WERAM-Prp-0079 EMJ03651 Prunus persica 82 2e-108 389
WERAM-Thc-0067 EOY11209 Theobroma cacao 83 2e-108 389
WERAM-Viv-0054 VIT_08s0007g07500.t01 Vitis vinifera 82 4e-108 387
WERAM-Pot-0169 POPTR_0019s04940.1 Populus trichocarpa 80 5e-107 384
WERAM-Met-0153 AES80833 Medicago truncatula 81 3e-105 378
WERAM-Glm-0250 GLYMA19G28680.1 Glycine max 80 9e-104 373
WERAM-Sot-0023 PGSC0003DMT400021581 Solanum tuberosum 76 2e-101 365
WERAM-Sol-0127 Solyc10g078520.1.1 Solanum lycopersicum 76 2e-101 365
WERAM-Mua-0083 GSMUA_Achr5P08980_001 Musa acuminata 71 2e-95 345
WERAM-Amt-0005 ERM93545 Amborella trichopoda 73 3e-95 345
WERAM-Ors-0035 OS03T0748200-01 Oryza sativa 65 4e-89 325
WERAM-Org-0039 ORGLA03G0311800.1 Oryza glaberrima 65 4e-89 325
WERAM-Orbr-0048 OB03G41110.1 Oryza brachyantha 66 5e-89 324
WERAM-Sob-0002 Sb01g008160.1 Sorghum bicolor 65 2e-88 322
WERAM-Sei-0133 Si037150m Setaria italica 66 3e-88 321
WERAM-Lep-0042 LPERR03G28650.1 Leersia perrieri 64 6e-87 317
WERAM-Zem-0151 GRMZM5G813111_P01 Zea mays 65 1e-86 317
WERAM-Brd-0002 BRADI1G08690.1 Brachypodium distachyon 65 2e-86 316
WERAM-Tra-0208 Traes_5BL_F2193F0FA.1 Triticum aestivum 63 4e-84 308
WERAM-Hov-0105 MLOC_7367.1 Hordeum vulgare 63 1e-83 306
WERAM-Php-0032 PP1S173_3V6.1 Physcomitrella patens 59 6e-78 287
WERAM-Sem-0143 EFJ29023 Selaginella moellendorffii 61 2e-75 279
WERAM-Gam-0113 ENSGMOP00000011971.1 Gadus morhua 35 5e-35 145
WERAM-Orn-0154 ENSONIP00000016230.1 Oreochromis niloticus 35 1e-34 144
WERAM-Gaa-0107 ENSGACP00000013626.1 Gasterosteus aculeatus 35 6e-34 141
WERAM-Pof-0162 ENSPFOP00000013201.1 Poecilia formosa 35 7e-34 141
WERAM-Tar-0028 ENSTRUP00000005742.1 Takifugu rubripes 34 5e-33 138
WERAM-Asm-0095 ENSAMXP00000009783.1 Astyanax mexicanus 33 4e-32 135
WERAM-Dar-0068 ENSDARP00000045244.4 Danio rerio 34 1e-31 134
WERAM-Tag-0163 ENSTGUP00000013715.1 Taeniopygia guttata 33 1e-31 134
WERAM-Gaga-0133 ENSGALP00000023298.1 Gallus gallus 33 1e-31 134
WERAM-Anc-0060 ENSACAP00000006051.2 Anolis carolinensis 33 1e-31 134
WERAM-Mum-0107 ENSMUSP00000032480.7 Mus musculus 33 2e-31 133
WERAM-Tub-0041 ENSTBEP00000005072.1 Tupaia belangeri 33 2e-31 133
WERAM-Mim-0061 ENSMICP00000006050.1 Microcebus murinus 33 2e-31 133
WERAM-Aim-0161 ENSAMEP00000014918.1 Ailuropoda melanoleuca 33 2e-31 133
WERAM-Paa-0054 ENSPANP00000015836.1 Papio anubis 33 2e-31 133
WERAM-Cii-0033 ENSCINP00000012930.3 Ciona intestinalis 33 3e-31 132
WERAM-Cap-0136 ENSCPOP00000011074.2 Cavia porcellus 33 4e-31 132
WERAM-Otg-0103 ENSOGAP00000008974.2 Otolemur garnettii 33 4e-31 132
WERAM-Loa-0090 ENSLAFP00000007029.3 Loxodonta africana 33 4e-31 132
WERAM-Fec-0076 ENSFCAP00000006388.3 Felis catus 33 4e-31 132
WERAM-Pat-0039 ENSPTRP00000007834.3 Pan troglodytes 33 4e-31 132
WERAM-Orc-0031 ENSOCUP00000003241.2 Oryctolagus cuniculus 33 5e-31 132
WERAM-Nol-0043 ENSNLEP00000005441.1 Nomascus leucogenys 33 5e-31 132
WERAM-Mam-0158 ENSMMUP00000022340.2 Macaca mulatta 33 5e-31 132
WERAM-Hos-0082 ENSP00000380024.4 Homo sapiens 33 5e-31 132
WERAM-Gog-0176 ENSGGOP00000015639.2 Gorilla gorilla 33 5e-31 132
WERAM-Chs-0123 ENSCSAP00000006623.1 Chlorocebus sabaeus 33 5e-31 132
WERAM-Caf-0153 ENSCAFP00000021782.3 Canis familiaris 33 5e-31 132
WERAM-Caj-0089 ENSCJAP00000014925.1 Callithrix jacchus 33 5e-31 132
WERAM-Ict-0084 ENSSTOP00000008871.2 Ictidomys tridecemlineatus 33 6e-31 131
WERAM-Ptv-0122 ENSPVAP00000010783.1 Pteropus vampyrus 33 7e-31 131
WERAM-Eqc-0207 ENSECAP00000022343.1 Equus caballus 33 7e-31 131
WERAM-Ran-0149 ENSRNOP00000024116.6 Rattus norvegicus 32 8e-31 131
WERAM-Mod-0170 ENSMODP00000022570.2 Monodelphis domestica 32 8e-31 131
WERAM-Sah-0173 ENSSHAP00000017995.1 Sarcophilus harrisii 32 1e-30 130
WERAM-Anp-0152 ENSAPLP00000015676.1 Anas platyrhynchos 33 2e-30 129
WERAM-Leo-0061 ENSLOCP00000008031.1 Lepisosteus oculatus 32 1e-29 127
WERAM-Ova-0071 ENSOARP00000007637.1 Ovis aries 31 1e-29 127
WERAM-Bot-0153 ENSBTAP00000022686.3 Bos taurus 31 1e-29 127
WERAM-Fia-0066 ENSFALP00000004954.1 Ficedula albicollis 33 1e-29 127
WERAM-Myl-0222 ENSMLUP00000018963.1 Myotis lucifugus 32 2e-29 126
WERAM-Orla-0124 ENSORLP00000015230.1 Oryzias latipes 35 2e-29 126
WERAM-Dan-0169 ENSDNOP00000024199.1 Dasypus novemcinctus 33 3e-29 125
WERAM-Ten-0205 ENSTNIP00000020777.1 Tetraodon nigroviridis 33 6e-29 125
WERAM-Mup-0002 ENSMPUP00000000187.1 Mustela putorius furo 32 7e-29 124
WERAM-Meg-0142 ENSMGAP00000014916.1 Meleagris gallopavo 32 8e-29 124
WERAM-Sus-0009 ENSSSCP00000000747.2 Sus scrofa 33 2e-28 123
WERAM-Pes-0145 ENSPSIP00000017141.1 Pelodiscus sinensis 33 2e-28 123
WERAM-Xet-0023 ENSXETP00000006501.3 Xenopus tropicalis 33 4e-28 122
WERAM-Xim-0139 ENSXMAP00000011311.1 Xiphophorus maculatus 31 2e-27 119
WERAM-Ocp-0059 ENSOPRP00000005127.2 Ochotona princeps 32 6e-27 118
WERAM-Mae-0101 ENSMEUP00000009824.1 Macropus eugenii 31 2e-26 116
WERAM-Chr-0037 EDP04619 Chlamydomonas reinhardtii 30 1e-25 114
WERAM-Poa-0041 ENSPPYP00000004780.2 Pongo abelii 33 2e-25 113
WERAM-Ora-0105 ENSOANP00000020022.2 Ornithorhynchus anatinus 34 2e-25 113
WERAM-Ere-0110 ENSEEUP00000011689.1 Erinaceus europaeus 32 2e-24 109
WERAM-Orm-0033 OMERI03G03370.1 Oryza meridionalis 31 5e-24 108
WERAM-Orni-0030 ONIVA03G03130.1 Oryza nivara 30 7e-24 108
WERAM-Ori-0037 BGIOSGA011837-PA Oryza indica 30 7e-24 108
WERAM-Orgl-0033 OGLUM03G03290.1 Oryza glumaepatula 30 2e-23 106
WERAM-Orp-0029 OPUNC03G03150.1 Oryza punctata 31 2e-23 106
WERAM-Prc-0117 ENSPCAP00000010314.1 Procavia capensis 36 1e-22 103
WERAM-Cym-0027 CMQ358CT Cyanidioschyzon merolae 30 2e-22 103
WERAM-Dio-0158 ENSDORP00000014787.1 Dipodomys ordii 34 5e-21 98.6
WERAM-Osl-0027 ABO99843 Ostreococcus lucimarinus 33 7e-21 98.2
WERAM-Tru-0022 TRIUR3_10173-P1 Triticum urartu 33 2e-20 97.1
WERAM-Soa-0068 ENSSARP00000006811.1 Sorex araneus 34 2e-20 96.7
WERAM-Cis-0018 ENSCSAVP00000004240.1 Ciona savignyi 59 3e-20 96.3
WERAM-Drm-0046 FBpp0080103 Drosophila melanogaster 63 3e-20 95.9
WERAM-Tut-0137 ENSTTRP00000011144.1 Tursiops truncatus 62 2e-19 93.2
WERAM-Arl-0064 fgenesh2_kg.3__ 2635__ AT3G24010.1 Arabidopsis lyrata 60 3e-19 92.8
WERAM-Chh-0082 ENSCHOP00000008858.1 Choloepus hoffmanni 67 4e-19 92.4
WERAM-Lac-0063 ENSLACP00000008528.1 Latimeria chalumnae 67 6e-19 91.7
Created Date 25-Jun-2016