Vicugna pacos      Me_Reader      PHD

※ PHD family introduction

    PHD: Distinct from the Royal family is the PHD finger, a well-characterized reader of H3K4me3. It contains a C4HC3 motif that coordinates two zinc ions in a cross-brace manner. Such an arrangement produces a globular domain with a small β-sheet and an α-helix. PHD fingers make extensive contacts with H3K4me3, imparting a high degree of specificity. (1)

Reference
1. Musselman CA, Lalonde ME, Cote J, Kutateladze TG.Perceiving the epigenetic landscape through histone readers. Nat Struct Mol Biol.2012;19(12):1218-27. PMID: 23211769.



There are 33 genes.  Reviewed (0 or Unreviewed (33

No.StatusWERAM IDGene/Alias Name
1
WERAM-Vip-0005
DIDO1
2
WERAM-Vip-0007
DPF2
3
WERAM-Vip-0013
KMT2C
4
WERAM-Vip-0018
BPTF
5
WERAM-Vip-0022
PHF8
6
WERAM-Vip-0024
NSD1
7
WERAM-Vip-0030
BAZ2B
8
WERAM-Vip-0034
BAZ1A
9
WERAM-Vip-0038
PHF20
10
WERAM-Vip-0039
INTS12
11
WERAM-Vip-0044
KDM5C
12
WERAM-Vip-0046
KAT6A
13
WERAM-Vip-0050
JADE3
14
WERAM-Vip-0054
KMT2A
15
WERAM-Vip-0056
ING2
16
WERAM-Vip-0061
KDM5B
17
WERAM-Vip-0065
PHF13
18
WERAM-Vip-0067
PHF12
19
WERAM-Vip-0070
PHF21A
20
WERAM-Vip-0072
TCF19
21
WERAM-Vip-0073
JADE1
22
WERAM-Vip-0080
KAT6B
23
WERAM-Vip-0082
TRIM24
24
WERAM-Vip-0093
KMT2E
25
WERAM-Vip-0096
UHRF2
26
WERAM-Vip-0100
PHF14
27
WERAM-Vip-0104
RSF1
28
WERAM-Vip-0105
KDM5A
29
WERAM-Vip-0109
CHD3
30
WERAM-Vip-0117
WHSC1L1
31
WERAM-Vip-0119
RAG2
32
WERAM-Vip-0123
PYGO1
33
WERAM-Vip-0124
PHF19