Tupaia belangeri      Me_Reader      PHD

※ PHD family introduction

    PHD: Distinct from the Royal family is the PHD finger, a well-characterized reader of H3K4me3. It contains a C4HC3 motif that coordinates two zinc ions in a cross-brace manner. Such an arrangement produces a globular domain with a small β-sheet and an α-helix. PHD fingers make extensive contacts with H3K4me3, imparting a high degree of specificity. (1)

Reference
1. Musselman CA, Lalonde ME, Cote J, Kutateladze TG.Perceiving the epigenetic landscape through histone readers. Nat Struct Mol Biol.2012;19(12):1218-27. PMID: 23211769.



There are 32 genes.  Reviewed (0 or Unreviewed (32

No.StatusWERAM IDGene/Alias Name
1
WERAM-Tub-0005
PHF3
2
WERAM-Tub-0007
JADE2
3
WERAM-Tub-0012
BAZ2A
4
WERAM-Tub-0013
PHF20L1
5
WERAM-Tub-0014
TRIM66
6
WERAM-Tub-0015
KAT6A
7
WERAM-Tub-0018
KDM5A
8
WERAM-Tub-0021
UHRF2
9
WERAM-Tub-0023
BRPF1
10
WERAM-Tub-0040
TRIM24
11
WERAM-Tub-0041
ING4
12
WERAM-Tub-0047
KDM5B
13
WERAM-Tub-0048
PHF1
14
WERAM-Tub-0051
KMT2B
15
WERAM-Tub-0061
KMT2E
16
WERAM-Tub-0070
DPF2
17
WERAM-Tub-0076
JADE3
18
WERAM-Tub-0077
PYGO1
19
WERAM-Tub-0079
KMT2A
20
WERAM-Tub-0085
CHD3
21
WERAM-Tub-0088
TAF3
22
WERAM-Tub-0094
KDM4A
23
WERAM-Tub-0096
CXXC1
24
WERAM-Tub-0107
WHSC1
25
WERAM-Tub-0120
PHF13
26
WERAM-Tub-0122
RSF1
27
WERAM-Tub-0127
BPTF
28
WERAM-Tub-0131
PHF14
29
WERAM-Tub-0136
BAZ2B
30
WERAM-Tub-0138
PHF10
31
WERAM-Tub-0140
KDM5C
32
WERAM-Tub-0145
PHF20