Tarsius syrichta      Me_Reader      PHD

※ PHD family introduction

    PHD: Distinct from the Royal family is the PHD finger, a well-characterized reader of H3K4me3. It contains a C4HC3 motif that coordinates two zinc ions in a cross-brace manner. Such an arrangement produces a globular domain with a small β-sheet and an α-helix. PHD fingers make extensive contacts with H3K4me3, imparting a high degree of specificity. (1)

Reference
1. Musselman CA, Lalonde ME, Cote J, Kutateladze TG.Perceiving the epigenetic landscape through histone readers. Nat Struct Mol Biol.2012;19(12):1218-27. PMID: 23211769.



There are 33 genes.  Reviewed (0 or Unreviewed (33

No.StatusWERAM IDGene/Alias Name
1
WERAM-Tas-0001
ING3
2
WERAM-Tas-0004
WHSC1L1
3
WERAM-Tas-0005
NSD1
4
WERAM-Tas-0007
KMT2D
5
WERAM-Tas-0013
BAZ2B
6
WERAM-Tas-0017
ING2
7
WERAM-Tas-0018
TRIM24
8
WERAM-Tas-0023
PHF3
9
WERAM-Tas-0024
PHF1
10
WERAM-Tas-0028
KMT2E
11
WERAM-Tas-0040
RSF1
12
WERAM-Tas-0050
KAT6A
13
WERAM-Tas-0051
PYGO1
14
WERAM-Tas-0052
JADE3
15
WERAM-Tas-0059
KAT6B
16
WERAM-Tas-0061
CHD4
17
WERAM-Tas-0070
INTS12
18
WERAM-Tas-0081
BAZ2A
19
WERAM-Tas-0083
BRD1
20
WERAM-Tas-0084
PHF14
21
WERAM-Tas-0090
BAZ1A
22
WERAM-Tas-0091
KDM5A
23
WERAM-Tas-0094
UHRF2
24
WERAM-Tas-0097
PHF10
25
WERAM-Tas-0106
KDM5B
26
WERAM-Tas-0109
KMT2A
27
WERAM-Tas-0113
PHF8
28
WERAM-Tas-0116
PHF21A
29
WERAM-Tas-0121
PHF20
30
WERAM-Tas-0123
WHSC1
31
WERAM-Tas-0124
DPF1
32
WERAM-Tas-0126
KMT2C
33
WERAM-Tas-0127
MTF2