Macropus eugenii      Me_Reader      PHD

※ PHD family introduction

    PHD: Distinct from the Royal family is the PHD finger, a well-characterized reader of H3K4me3. It contains a C4HC3 motif that coordinates two zinc ions in a cross-brace manner. Such an arrangement produces a globular domain with a small β-sheet and an α-helix. PHD fingers make extensive contacts with H3K4me3, imparting a high degree of specificity. (1)

Reference
1. Musselman CA, Lalonde ME, Cote J, Kutateladze TG.Perceiving the epigenetic landscape through histone readers. Nat Struct Mol Biol.2012;19(12):1218-27. PMID: 23211769.



There are 39 genes.  Reviewed (0 or Unreviewed (39

No.StatusWERAM IDGene/Alias Name
1
WERAM-Mae-0003
KMT2A
2
WERAM-Mae-0007
PYGO2
3
WERAM-Mae-0009
PHF14
4
WERAM-Mae-0012
KAT6B
5
WERAM-Mae-0018
CXXC1
6
WERAM-Mae-0021
KMT2C
7
WERAM-Mae-0028
PHRF1
8
WERAM-Mae-0032
BRD1
9
WERAM-Mae-0046
JADE1
10
WERAM-Mae-0050
PHF19
11
WERAM-Mae-0052
BRPF1
12
WERAM-Mae-0054
CHD3
13
WERAM-Mae-0055
PHF1
14
WERAM-Mae-0061
BAZ1B
15
WERAM-Mae-0064
KMT2D
16
WERAM-Mae-0069
PHF12
17
WERAM-Mae-0073
PHF10
18
WERAM-Mae-0078
19
WERAM-Mae-0079
ING2
20
WERAM-Mae-0081
CHD5
21
WERAM-Mae-0084
INTS12
22
WERAM-Mae-0086
DPF1
23
WERAM-Mae-0091
WHSC1
24
WERAM-Mae-0098
BPTF
25
WERAM-Mae-0101
ING4
26
WERAM-Mae-0102
DPF2
27
WERAM-Mae-0104
BAZ1A
28
WERAM-Mae-0106
BAZ2B
29
WERAM-Mae-0107
PHF21B
30
WERAM-Mae-0112
PHF13
31
WERAM-Mae-0114
WHSC1L1
32
WERAM-Mae-0117
JADE3
33
WERAM-Mae-0118
PHF23
34
WERAM-Mae-0124
ING3
35
WERAM-Mae-0127
ING1
36
WERAM-Mae-0133
KMT2B
37
WERAM-Mae-0134
PHF21A
38
WERAM-Mae-0136
KDM5B
39
WERAM-Mae-0141
KDM5A