Choloepus hoffmanni      Me_Reader      PHD

※ PHD family introduction

    PHD: Distinct from the Royal family is the PHD finger, a well-characterized reader of H3K4me3. It contains a C4HC3 motif that coordinates two zinc ions in a cross-brace manner. Such an arrangement produces a globular domain with a small β-sheet and an α-helix. PHD fingers make extensive contacts with H3K4me3, imparting a high degree of specificity. (1)

Reference
1. Musselman CA, Lalonde ME, Cote J, Kutateladze TG.Perceiving the epigenetic landscape through histone readers. Nat Struct Mol Biol.2012;19(12):1218-27. PMID: 23211769.



There are 31 genes.  Reviewed (0 or Unreviewed (31

No.StatusWERAM IDGene/Alias Name
1
WERAM-Chh-0001
KAT6B
2
WERAM-Chh-0003
CHD4
3
WERAM-Chh-0008
KMT2C
4
WERAM-Chh-0010
KMT2B
5
WERAM-Chh-0014
BRPF1
6
WERAM-Chh-0015
KMT2E
7
WERAM-Chh-0017
TRIM33
8
WERAM-Chh-0029
PHF3
9
WERAM-Chh-0038
TAF3
10
WERAM-Chh-0040
BAZ1B
11
WERAM-Chh-0042
WHSC1
12
WERAM-Chh-0043
PHF20
13
WERAM-Chh-0044
ING3
14
WERAM-Chh-0055
KMT2A
15
WERAM-Chh-0056
BAZ2A
16
WERAM-Chh-0058
DIDO1
17
WERAM-Chh-0060
RSF1
18
WERAM-Chh-0061
KDM5A
19
WERAM-Chh-0069
PYGO1
20
WERAM-Chh-0072
KAT6A
21
WERAM-Chh-0074
WHSC1L1
22
WERAM-Chh-0075
UHRF2
23
WERAM-Chh-0080
BAZ1A
24
WERAM-Chh-0082
ING1
25
WERAM-Chh-0090
BPTF
26
WERAM-Chh-0091
INTS12
27
WERAM-Chh-0094
KDM5B
28
WERAM-Chh-0099
PHF12
29
WERAM-Chh-0111
30
WERAM-Chh-0112
PHF14
31
WERAM-Chh-0117
JADE1