Latimeria chalumnae      Me_Reader      MBT

※ MBT family introduction

    MBT: MBT reads lower methylation states, recognizing mono- and dimethylated lysines. All MBTs characterized at present contain two to four repeats of ~100 amino acids. The most common three-repeat 3MBT module folds in a propeller-like structure, and the four-repeat 4MBT module has an asymmetric rhombus architecture29-32. Notably, although each MBT repeat contains an aromatic cage, which also includes an acidic residue, only the second repeat binds methyllysine. (1)

Reference
1. Musselman CA, Lalonde ME, Cote J, Kutateladze TG.Perceiving the epigenetic landscape through histone readers. Nat Struct Mol Biol.2012;19(12):1218-27. PMID: 23211769.



There are 8 genes.  Reviewed (0 or Unreviewed (8

No.StatusWERAM IDGene/Alias Name
1
WERAM-Lac-0023
L3MBTL1
2
WERAM-Lac-0026
SCML2
3
WERAM-Lac-0031
SFMBT1
4
WERAM-Lac-0033
MBTD1
5
WERAM-Lac-0059
L3MBTL2
6
WERAM-Lac-0077
l3mbtl1b
7
WERAM-Lac-0133
SFMBT2
8
WERAM-Lac-0144
SCMH1