Astyanax mexicanus      Me_Reader      MBT

※ MBT family introduction

    MBT: MBT reads lower methylation states, recognizing mono- and dimethylated lysines. All MBTs characterized at present contain two to four repeats of ~100 amino acids. The most common three-repeat 3MBT module folds in a propeller-like structure, and the four-repeat 4MBT module has an asymmetric rhombus architecture29-32. Notably, although each MBT repeat contains an aromatic cage, which also includes an acidic residue, only the second repeat binds methyllysine. (1)

Reference
1. Musselman CA, Lalonde ME, Cote J, Kutateladze TG.Perceiving the epigenetic landscape through histone readers. Nat Struct Mol Biol.2012;19(12):1218-27. PMID: 23211769.



There are 12 genes.  Reviewed (0 or Unreviewed (12

No.StatusWERAM IDGene/Alias Name
1
WERAM-Asm-0013
2
WERAM-Asm-0014
scmh1
3
WERAM-Asm-0042
l3mbtl1b
4
WERAM-Asm-0044
sfmbt2
5
WERAM-Asm-0080
MBTD1 (1 to many)
6
WERAM-Asm-0082
scml2
7
WERAM-Asm-0085
l3mbtl1a
8
WERAM-Asm-0106
l3mbtl3
9
WERAM-Asm-0117
mbtd1
10
WERAM-Asm-0170
sfmbt1
11
WERAM-Asm-0196
l3mbtl2
12
WERAM-Asm-0199
L3MBTL4