Danio rerio      Me_Reader      Chromodomain

※ Chromodomain family introduction

    Chromodomain: The chromodomain is the smallest member, consisting of four curved β-strands and an α-helix. The chromodomains of HP1 and Polycomb were found to recognize histone H3 trimethylated at K9 (H3K9me3) and H3K27me3, respectively, and these proteins were the first examples of readers specific for methyllysine. Chromodomains generally prefer trimethylated lysine, though some have been shown to bind dimethylated species. The aromatic cage of the chromodomain of mouse and fly HP1 contains an aspartate or glutamate residue, accounting for its ability to interact well with H3K9me3 and dimethylated H3K9 (H3K9me2). (1)

Reference
1. Musselman CA, Lalonde ME, Cote J, Kutateladze TG.Perceiving the epigenetic landscape through histone readers. Nat Struct Mol Biol.2012;19(12):1218-27. PMID: 23211769.



There are 10 genes.  Reviewed (0 or Unreviewed (10

No.StatusWERAM IDGene/Alias Name
1
WERAM-Dar-0084
cbx7a
2
WERAM-Dar-0088
cdyl
3
WERAM-Dar-0099
cbx2
4
WERAM-Dar-0163
cbx6a
5
WERAM-Dar-0188
cbx7b
6
WERAM-Dar-0189
cbx8a
7
WERAM-Dar-0194
cbx3b
8
WERAM-Dar-0197
cbx6b
9
WERAM-Dar-0200
cbx8b
10
WERAM-Dar-0204
cbx4