Homo sapiens      Me_Reader      Ankyrin

※ Ankyrin family introduction

    Ankyrin: Owing to extensive intermolecular contacts, the ankyrin repeats of G9a and GLP and the BAH domain of ORC1 show high specificity for di- or monomethylated H3K9 and H4K20me2, respectively. The H3K9me2 peptide is sandwiched between the β-turns and α-helices of the fourth and fifth ankyrin repeats, whereas K9me2 fits into the aromatic cage also containing a glutamate. (1)

Reference
1. Musselman CA, Lalonde ME, Cote J, Kutateladze TG.Perceiving the epigenetic landscape through histone readers. Nat Struct Mol Biol.2012;19(12):1218-27. PMID: 23211769.



There are 9 genes.  Reviewed (2 or Unreviewed (7

No.StatusWERAM IDGene/Alias Name
1
WERAM-Hos-0211
EHMT1; GLP; GLP1; KMT1D; FP13812; EUHMTASE1; Eu-HMTase1; bA188C12.1; KIAA1876
2
WERAM-Hos-0242
EHMT2; G9A; BAT8; GAT8; NG36; KMT1C; C6orf30
3
WERAM-Hos-0147
ANK2
4
WERAM-Hos-0239
EHMT2
5
WERAM-Hos-0247
EHMT2
6
WERAM-Hos-0252
EHMT2
7
WERAM-Hos-0253
EHMT2
8
WERAM-Hos-0261
EHMT2
9
WERAM-Hos-0262
EHMT2