Triticum aestivum      HMT      SUV39

※ SUV39 family introduction

    SUV39: The Su(var)3-9 gene was originally identified in a genetic screen as a suppressor of position effect variegation in Drosophila. This was the first hint that the Su(var)3-9 protein might be involved in regulating chromatin structure. In mice, there are two highly related homologues of the Drosophila Su(var)3-9, Suv39h1 and Suv39h2. Following the identification of Suv39h1 as a lysine methyltransferase capable of methylating Lys9 of histone H3 (H3K9), confirmation that this protein can modulate chromatin architecture came with the finding that it creates a specific binding site for the heterochromatin protein HP1. As Suv39h1 and HP1 interact, it is thought that Suv39h1 methylating H3 K9, and then HP1 binding to the methylated H3, forms a positive feedback loop allowing HP1 and H3 K9 methylation to spread along chromatin, generating repressive heterochromatin in the process. (1)

Reference
1. Schneider R, Bannister AJ, Kouzarides T.Unsafe SETs: histone lysine methyltransferases and cancer. Trends Biochem Sci.2002;27(8):396-402. PMID: 12151224.



There are 50 genes.  Reviewed (0 or Unreviewed (50

No.StatusWERAM IDGene/Alias Name
1
WERAM-Tra-0001
2
WERAM-Tra-0002
3
WERAM-Tra-0003
4
WERAM-Tra-0010
5
WERAM-Tra-0014
6
WERAM-Tra-0015
7
WERAM-Tra-0018
8
WERAM-Tra-0019
9
WERAM-Tra-0028
10
WERAM-Tra-0031
11
WERAM-Tra-0034
12
WERAM-Tra-0039
13
WERAM-Tra-0040
14
WERAM-Tra-0041
15
WERAM-Tra-0051
16
WERAM-Tra-0058
17
WERAM-Tra-0060
18
WERAM-Tra-0062
19
WERAM-Tra-0066
20
WERAM-Tra-0067
21
WERAM-Tra-0080
22
WERAM-Tra-0082
23
WERAM-Tra-0085
24
WERAM-Tra-0087
25
WERAM-Tra-0092
26
WERAM-Tra-0103
27
WERAM-Tra-0115
28
WERAM-Tra-0121
29
WERAM-Tra-0134
30
WERAM-Tra-0146
31
WERAM-Tra-0156
32
WERAM-Tra-0171
33
WERAM-Tra-0172
34
WERAM-Tra-0174
35
WERAM-Tra-0201
36
WERAM-Tra-0204
37
WERAM-Tra-0215
38
WERAM-Tra-0226
39
WERAM-Tra-0237
40
WERAM-Tra-0247
41
WERAM-Tra-0251
42
WERAM-Tra-0312
43
WERAM-Tra-0314
44
WERAM-Tra-0317
45
WERAM-Tra-0318
46
WERAM-Tra-0331
47
WERAM-Tra-0332
48
WERAM-Tra-0338
TRAES_3BF027700050CFD_c1
49
WERAM-Tra-0342
TRAES_3BF048700110CFD_c1
50
WERAM-Tra-0355
TRAES_3BF156000060CFD_c1