Theobroma cacao      HDM      JHDM2

※ JHDM2 family introduction

    JHDM2: The JHDM2 family of proteins have orthologues from flies to humans; they possess JmjC and modified zinc finger domains. The mammalian JHDM2 family is comprised of four human proteins: hairless (HR), JHDM2A, JHDM2B, and JHDM2C. HR was originally identified in mice, and its mutation results in universal congenital alopecia. Mutation in its human homologue also causes hereditary alopecia. HR is expressed in the skin and the brain, where it probably functions as a corepressor of the thyroid hormone receptor. (1)

Reference
1. Klose RJ,Kallin EM,Zhang Y (2007)JmjC-domain-containing proteins and histone demethylation. Nat Rev Genet., 7:715-727. PMID: 16983801.



There are 8 genes.  Reviewed (0 or Unreviewed (8

No.StatusWERAM IDGene/Alias Name
1
WERAM-Thc-0027
TCM_007714
2
WERAM-Thc-0038
TCM_015416
3
WERAM-Thc-0068
TCM_026634
4
WERAM-Thc-0080
TCM_030013
5
WERAM-Thc-0081
TCM_030286
6
WERAM-Thc-0088
TCM_033453
7
WERAM-Thc-0089
TCM_033531
8
WERAM-Thc-0124
TCM_046989