JARID: The JARID group of proteins contains two subgroups: JARID1 and JARID2. In higher eukaryotes, the JARID1 subgroup contains JmjN, AT-rich interactive, C5HC2-zinc-finger and PHD-finger domains. The JARID2 subgroup does not contain PHD domains, and its Drosophila homologue lacks the C5HC2-zinc-finger domain. The mammalian JARID1 homologues can function as transcriptional co-activators or corepressors, indicating that their substrate specificity could be uniquely tailored to their distinct functions in modulating transcription. (1)

Reference
1. Klose RJ,Kallin EM,Zhang Y (2010)JmjC-domain-containing proteins and histone demethylation. Nat Rev Genet., 7:715-727. PMID: 16983801.