Selaginella moellendorffii      HDAC      Class-I

※ Class-I family introduction

    Class-I: Class I HDACs share homology with the yeast Rpd3. This class includes HDACs 1, 2, 3, and 8, and its members are expressed ubiquitously in humans. Members 1, 2, and 3 are found in multi-protein repressor complexes in the nucleus, where they regulate gene expression. HDAC8 is found in both the nucleus and cytoplasm, and while it has not been found in any multi-protein complexes, it has been described to be involved in transcriptional repression. (1)

Reference
1. Koeneke, E., Witt, O., & Oehme, I.HDAC Family Members Intertwined in the Regulation of Autophagy: A Druggable Vulnerability in Aggressive Tumor Entities. Cells.2015;4(2):135-168. PMID: 25915736.



There are 19 genes.  Reviewed (0 or Unreviewed (19

No.StatusWERAM IDGene/Alias Name
1
WERAM-Sem-0010
SELMODRAFT_110614
2
WERAM-Sem-0013
SELMODRAFT_114783 SELMODRAFT_80012
3
WERAM-Sem-0019
SELMODRAFT_129097
4
WERAM-Sem-0022
SELMODRAFT_131541
5
WERAM-Sem-0034
SELMODRAFT_161290
6
WERAM-Sem-0037
SELMODRAFT_166606
7
WERAM-Sem-0039
SELMODRAFT_169296
8
WERAM-Sem-0041
SELMODRAFT_170187
9
WERAM-Sem-0043
SELMODRAFT_172161
10
WERAM-Sem-0047
SELMODRAFT_179763
11
WERAM-Sem-0048
SELMODRAFT_180494
12
WERAM-Sem-0051
SELMODRAFT_185423
13
WERAM-Sem-0056
HDA19-1 SELMODRAFT_234196
14
WERAM-Sem-0090
SELMODRAFT_429326
15
WERAM-Sem-0097
SELMODRAFT_432551
16
WERAM-Sem-0116
SELMODRAFT_448239
17
WERAM-Sem-0128
SELMODRAFT_84957
18
WERAM-Sem-0132
SELMODRAFT_74186
19
WERAM-Sem-0137