Gadus morhua      HAT      MYST

※ MYST family introduction

    MYST: The MYST family, which was named after the initials of the founding members: MOZ, Ybf2/Sas3, Sas2, and Tip60, is the largest family of acetyltransferases with diverse biological functions. In the budding yeast, Esa1 of the NuA4 complex is known to be an essential HAT required for DNA repair and cell cycle progression. In animal systems, the role of MYST family HATs in stem cells, development and cancer have been thoroughly documented. It is of note that MYST family HAT complexes are known to have the broadest range of substrates including non-histone targets. The regulatory role and the ubiquity of protein acetylation had long been suspected to be comparable that of phosphorylation. (1)

Reference
1. Jeon J. H., Lee Y. H.Histone acetylation in fungal pathogens of plants. Plant Pathol.J.2014;30(1):1-9. PMID: 25288980.



There are 6 genes.  Reviewed (0 or Unreviewed (6

No.StatusWERAM IDGene/Alias Name
1
WERAM-Gam-0003
kat6b
2
WERAM-Gam-0032
kat7a
3
WERAM-Gam-0083
kat6a
4
WERAM-Gam-0136
kat5b
5
WERAM-Gam-0139
kat7b
6
WERAM-Gam-0165
kat8