Candida glabrata      HAT      MYST

※ MYST family introduction

    MYST: The MYST family, which was named after the initials of the founding members: MOZ, Ybf2/Sas3, Sas2, and Tip60, is the largest family of acetyltransferases with diverse biological functions. In the budding yeast, Esa1 of the NuA4 complex is known to be an essential HAT required for DNA repair and cell cycle progression. In animal systems, the role of MYST family HATs in stem cells, development and cancer have been thoroughly documented. It is of note that MYST family HAT complexes are known to have the broadest range of substrates including non-histone targets. The regulatory role and the ubiquity of protein acetylation had long been suspected to be comparable that of phosphorylation. (1)

Reference
1. Jeon J. H., Lee Y. H.Histone acetylation in fungal pathogens of plants. Plant Pathol.J.2014;30(1):1-9. PMID: 25288980.



There are 2 genes.  Reviewed (0 or Unreviewed (2

No.StatusWERAM IDGene/Alias Name
1
WERAM-Cag-0002
AO440_000122 AO441_000095
2
WERAM-Cag-0019
AO438_002995 AO439_002988 AO440_002941 AO441_002841 AO442_002954 AO443_002835