Triticum urartu      Ac_Reader      Bromodomain

※ Bromodomain family introduction

    Bromodomain: Bromodomains (BRDs) are protein interaction modules that exclusively recognize acetylation motifs. BRDs are evolutionarily conserved and present in diverse nuclear proteins comprising HATs (GCN5, PCAF), ATP-dependent chromatin-remodeling complexes (BAZ1B), helicases (SMARCA), methyltransferases (MLL, ASH1L), transcriptional coactivators (TRIM/TIF1, TAFs) transcriptional mediators (TAF1), nuclear-scaffolding proteins(PB1), and the BET family. Despite large sequence variations, all BRD modules share a conserved fold that comprises a left-handed bundle of four a helices, linked by loop regions of variablelength, which line the Kac binding site and determine binding specificity. (1)

Reference
1. P. Filippakopoulos, S. Picaud, M. Mangos, T. Keates, J.P. Lambert, D. Barsyte-Lovejoy, I. Felletar, R. Volkmer, S. Müller, T. Pawson,et al.Histone recognition and large-scale structural analysis of the human bromodomain family. Cell.2012;149(1):214-231. PMID: 22464331.



There are 18 genes.  Reviewed (0 or Unreviewed (18

No.StatusWERAM IDGene/Alias Name
1
WERAM-Tru-0005
TRIUR3_02881
2
WERAM-Tru-0010
TRIUR3_05662
3
WERAM-Tru-0017
TRIUR3_07486
4
WERAM-Tru-0018
TRIUR3_07786
5
WERAM-Tru-0019
6
WERAM-Tru-0026
TRIUR3_14164
7
WERAM-Tru-0027
TRIUR3_14219
8
WERAM-Tru-0045
TRIUR3_20497
9
WERAM-Tru-0057
TRIUR3_23361
10
WERAM-Tru-0062
TRIUR3_25198
11
WERAM-Tru-0068
12
WERAM-Tru-0069
TRIUR3_26466
13
WERAM-Tru-0072
TRIUR3_27288
14
WERAM-Tru-0074
TRIUR3_27913
15
WERAM-Tru-0075
TRIUR3_28030
16
WERAM-Tru-0078
TRIUR3_28812
17
WERAM-Tru-0083
TRIUR3_30335
18
WERAM-Tru-0088