Oryza rufipogon      Ac_Reader      Bromodomain

※ Bromodomain family introduction

    Bromodomain: Bromodomains (BRDs) are protein interaction modules that exclusively recognize acetylation motifs. BRDs are evolutionarily conserved and present in diverse nuclear proteins comprising HATs (GCN5, PCAF), ATP-dependent chromatin-remodeling complexes (BAZ1B), helicases (SMARCA), methyltransferases (MLL, ASH1L), transcriptional coactivators (TRIM/TIF1, TAFs) transcriptional mediators (TAF1), nuclear-scaffolding proteins(PB1), and the BET family. Despite large sequence variations, all BRD modules share a conserved fold that comprises a left-handed bundle of four a helices, linked by loop regions of variablelength, which line the Kac binding site and determine binding specificity. (1)

Reference
1. P. Filippakopoulos, S. Picaud, M. Mangos, T. Keates, J.P. Lambert, D. Barsyte-Lovejoy, I. Felletar, R. Volkmer, S. Müller, T. Pawson,et al.Histone recognition and large-scale structural analysis of the human bromodomain family. Cell.2012;149(1):214-231. PMID: 22464331.



There are 21 genes.  Reviewed (0 or Unreviewed (21

No.StatusWERAM IDGene/Alias Name
1
WERAM-Orr-0002
2
WERAM-Orr-0007
3
WERAM-Orr-0021
4
WERAM-Orr-0024
5
WERAM-Orr-0029
6
WERAM-Orr-0035
7
WERAM-Orr-0046
8
WERAM-Orr-0047
9
WERAM-Orr-0059
10
WERAM-Orr-0065
11
WERAM-Orr-0069
12
WERAM-Orr-0078
13
WERAM-Orr-0079
14
WERAM-Orr-0081
15
WERAM-Orr-0089
16
WERAM-Orr-0091
17
WERAM-Orr-0093
18
WERAM-Orr-0099
19
WERAM-Orr-0108
20
WERAM-Orr-0109
21
WERAM-Orr-0111