Oryza indica      Ac_Reader      Bromodomain

※ Bromodomain family introduction

    Bromodomain: Bromodomains (BRDs) are protein interaction modules that exclusively recognize acetylation motifs. BRDs are evolutionarily conserved and present in diverse nuclear proteins comprising HATs (GCN5, PCAF), ATP-dependent chromatin-remodeling complexes (BAZ1B), helicases (SMARCA), methyltransferases (MLL, ASH1L), transcriptional coactivators (TRIM/TIF1, TAFs) transcriptional mediators (TAF1), nuclear-scaffolding proteins(PB1), and the BET family. Despite large sequence variations, all BRD modules share a conserved fold that comprises a left-handed bundle of four a helices, linked by loop regions of variablelength, which line the Kac binding site and determine binding specificity. (1)

Reference
1. P. Filippakopoulos, S. Picaud, M. Mangos, T. Keates, J.P. Lambert, D. Barsyte-Lovejoy, I. Felletar, R. Volkmer, S. Müller, T. Pawson,et al.Histone recognition and large-scale structural analysis of the human bromodomain family. Cell.2012;149(1):214-231. PMID: 22464331.



There are 21 genes.  Reviewed (0 or Unreviewed (21

No.StatusWERAM IDGene/Alias Name
1
WERAM-Ori-0004
OsI_03067
2
WERAM-Ori-0009
OsI_00884
3
WERAM-Ori-0018
OsI_07959
4
WERAM-Ori-0024
OsI_06575
5
WERAM-Ori-0036
OsI_09853
6
WERAM-Ori-0041
OsI_11421
7
WERAM-Ori-0047
OsI_17475
8
WERAM-Ori-0048
OsI_17470
9
WERAM-Ori-0064
OsI_23890
10
WERAM-Ori-0065
OsI_23891
11
WERAM-Ori-0070
OsI_21551
12
WERAM-Ori-0074
OsI_22908
13
WERAM-Ori-0078
OsI_26500
14
WERAM-Ori-0085
OsI_26141
15
WERAM-Ori-0086
OsI_26165
16
WERAM-Ori-0091
OsI_29838
17
WERAM-Ori-0092
OsI_27669
18
WERAM-Ori-0095
OsI_27549
19
WERAM-Ori-0097
OsI_28113
20
WERAM-Ori-0102
OsI_32297
21
WERAM-Ori-0114
OsI_33575