Musa acuminata      Ac_Reader      Bromodomain

※ Bromodomain family introduction

    Bromodomain: Bromodomains (BRDs) are protein interaction modules that exclusively recognize acetylation motifs. BRDs are evolutionarily conserved and present in diverse nuclear proteins comprising HATs (GCN5, PCAF), ATP-dependent chromatin-remodeling complexes (BAZ1B), helicases (SMARCA), methyltransferases (MLL, ASH1L), transcriptional coactivators (TRIM/TIF1, TAFs) transcriptional mediators (TAF1), nuclear-scaffolding proteins(PB1), and the BET family. Despite large sequence variations, all BRD modules share a conserved fold that comprises a left-handed bundle of four a helices, linked by loop regions of variablelength, which line the Kac binding site and determine binding specificity. (1)

Reference
1. P. Filippakopoulos, S. Picaud, M. Mangos, T. Keates, J.P. Lambert, D. Barsyte-Lovejoy, I. Felletar, R. Volkmer, S. Müller, T. Pawson,et al.Histone recognition and large-scale structural analysis of the human bromodomain family. Cell.2012;149(1):214-231. PMID: 22464331.



There are 33 genes.  Reviewed (0 or Unreviewed (33

No.StatusWERAM IDGene/Alias Name
1
WERAM-Mua-0002
2
WERAM-Mua-0011
3
WERAM-Mua-0014
4
WERAM-Mua-0018
5
WERAM-Mua-0022
6
WERAM-Mua-0024
7
WERAM-Mua-0025
8
WERAM-Mua-0028
9
WERAM-Mua-0032
10
WERAM-Mua-0034
11
WERAM-Mua-0039
12
WERAM-Mua-0045
13
WERAM-Mua-0049
14
WERAM-Mua-0050
15
WERAM-Mua-0051
16
WERAM-Mua-0052
17
WERAM-Mua-0067
18
WERAM-Mua-0071
19
WERAM-Mua-0077
20
WERAM-Mua-0105
21
WERAM-Mua-0111
22
WERAM-Mua-0113
23
WERAM-Mua-0115
24
WERAM-Mua-0116
25
WERAM-Mua-0118
26
WERAM-Mua-0119
27
WERAM-Mua-0126
28
WERAM-Mua-0129
29
WERAM-Mua-0137
30
WERAM-Mua-0140
31
WERAM-Mua-0141
32
WERAM-Mua-0150
33
WERAM-Mua-0152