Takifugu rubripes      Me_Reader      Chromodomain

※ Chromodomain family introduction

    Chromodomain: The chromodomain is the smallest member, consisting of four curved β-strands and an α-helix. The chromodomains of HP1 and Polycomb were found to recognize histone H3 trimethylated at K9 (H3K9me3) and H3K27me3, respectively, and these proteins were the first examples of readers specific for methyllysine. Chromodomains generally prefer trimethylated lysine, though some have been shown to bind dimethylated species. The aromatic cage of the chromodomain of mouse and fly HP1 contains an aspartate or glutamate residue, accounting for its ability to interact well with H3K9me3 and dimethylated H3K9 (H3K9me2). (1)

Reference
1. Musselman CA, Lalonde ME, Cote J, Kutateladze TG.Perceiving the epigenetic landscape through histone readers. Nat Struct Mol Biol.2012;19(12):1218-27. PMID: 23211769.



There are 12 genes.  Reviewed (0 or Unreviewed (12

No.StatusWERAM IDGene/Alias Name
1
WERAM-Tar-0020
CBX4
2
WERAM-Tar-0023
cbx8b
3
WERAM-Tar-0024
cbx2
4
WERAM-Tar-0026
cbx4
5
WERAM-Tar-0029
cbx8a
6
WERAM-Tar-0035
cbx2
7
WERAM-Tar-0039
cbx6a
8
WERAM-Tar-0082
cbx7a
9
WERAM-Tar-0143
cbx1b
10
WERAM-Tar-0188
cbx3b
11
WERAM-Tar-0211
cbx7b
12
WERAM-Tar-0221
CDYL2