Musa acuminata      HDAC      Class-I

※ Class-I family introduction

    Class-I: Class I HDACs share homology with the yeast Rpd3. This class includes HDACs 1, 2, 3, and 8, and its members are expressed ubiquitously in humans. Members 1, 2, and 3 are found in multi-protein repressor complexes in the nucleus, where they regulate gene expression. HDAC8 is found in both the nucleus and cytoplasm, and while it has not been found in any multi-protein complexes, it has been described to be involved in transcriptional repression. (1)

Reference
1. Koeneke, E., Witt, O., & Oehme, I.HDAC Family Members Intertwined in the Regulation of Autophagy: A Druggable Vulnerability in Aggressive Tumor Entities. Cells.2015;4(2):135-168. PMID: 25915736.



There are 14 genes.  Reviewed (0 or Unreviewed (14

No.StatusWERAM IDGene/Alias Name
1
WERAM-Mua-0015
2
WERAM-Mua-0033
HDAC19
3
WERAM-Mua-0044
4
WERAM-Mua-0048
5
WERAM-Mua-0066
6
WERAM-Mua-0081
7
WERAM-Mua-0089
8
WERAM-Mua-0091
9
WERAM-Mua-0104
10
WERAM-Mua-0114
HDAC6
11
WERAM-Mua-0121
12
WERAM-Mua-0145
13
WERAM-Mua-0148
14
WERAM-Mua-0158