WERAM Information

Tag Content
WERAM ID WERAM-Drm-0022
Ensembl Protein ID FBpp0070347
Uniprot Accession Q8IRW8; TRR_DROME; O46083; Q8MYR5; Q8T9I7; Q9W548
Genbank Protein ID NP_525040.2; NP_726773.2
Protein Name Histone-lysine N-methyltransferase trr
Genbank Nucleotide ID NM_080301.3; NM_166911.4
Gene Name TRR
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
FBgn0023518 FBtr0070363 FBpp0070347
FBgn0023518 FBtr0070362 FBpp0070346
Details
Type Family Domain Substrates AA References (PMIDs)
HMT SET1 SET H3K4 K 20236312
Status Reviewed
Classification
Type Family E-value Score Start End
HMT SET1 5.90e-45 152.8 2292 2407
Organism Drosophila melanogaster
NCBI Taxa ID 7227
Functional Description
(View)		 Histone methyltransferase that acts as a coactivator for the ecdysone receptor during development. Specifically trimethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation. Recruited by EcR in an ecdysone-dependent manner causing H3 'Lys-4' trimethylation at ecdysone-inducible promoters, leading to activate expression. Plays a central role in the developing compound eye, during the progression of the morphogenetic furrow and in post-furrow differentiation of the retinal epithelium, notably by activating expression of hh. Also required for wing and abdominal development.
Domain Profile
  HMT SET1
     SET1.txt    2 elevakskikglglvakkeiekeelviEYvGevirsevadkrekeyekkeigvylfrldedaevvvdatkkgniarfinhscepNceakvvavdge 97  
                   ++++a+ski+glgl+a+++iek++++iEY+Gevir+ev++ rek+ye+k++g+y+frlded   vvdat  g+ ar+inhsc+pNc++++v+vd++
  FBpp0070347 2292 NVYLARSKIQGLGLYAARDIEKHTMIIEYIGEVIRTEVSEIREKQYESKNRGIYMFRLDED--RVVDATLSGGLARYINHSCNPNCVTEIVEVDRD 2385
                   7999*********************************************************..********************************* PP
     SET1.txt   98 kkiviyakraIekgeeltydYk 119 
                    +i+i+akr+I +geel ydYk
  FBpp0070347 2386 VRIIIFAKRKIYRGEELSYDYK 2407
                   *********************7 PP
Protein Sequence
(Fasta)		MNIPKVTTSL GAAEKAKPER VASVAAAAFN AVSLQKRSGD DTATPAEDPT RKKAKTELLL 60
GTGTAAPSLP AKASSTAPQQ LLYQRSGQQA KAQVKAASEP QDVETADGVW DARDQQIIVC 120
NFGSGTEMGA IKAEDADKQS EYRISTPRNS QSNPLLHRNT AFTSFTKKEG ASSSASSSSS 180
TASVISIEPS GSGQDHAENS GKSEDLDYVL MPASGADSST SVGNSTGTGT PAGTPIGATT 240
STIILNANNG TAGVSGAGTT TILTQKSGHT NYNIFNTTAT GSQTPTTTLL NRVNLHPKMK 300
TQLMVNAKKL SEVTQTTAKV SIGNKTISVP LLKPLMSASG AATAGGATIV ESKQLLQPGG 360
QVTTVMSAAQ QSGGQQVHPH VHSHAHHNFT KLIKRGPKNS GTIVSFSGLQ IKPANTKIVA 420
TKVVSKKMLQ LQQHQQQIQQ QQQLQQLQVT SGGGLAPPTG SIVTITTTNP SQTYAMVQDS 480
ATVGPAAHSE DDAPAPRKIT AYSENLQKIL NKSKSQESTG GPEEFTNINS VVIKPLDKNT 540
LNCPPSFNIF KQQQHSQAAQ SQSISAVGSG AGTPVTFTMA SGNASDLATT STVSVSAGTI 600
CINSPMMGTR PIISIQNKNI SLVLSKTTMA QQKPKMITTT TLSSQAALQM HHALIQDSSA 660
DKAGSSANSG SATSGASMQL KLTTANTPTK LSVSLAPDVV KLEEVGSESK AKLLVKQEAV 720
VKDSTGTPTS EERAEEIGTP EKRLNANATM TAINQVQNQS ANQIQMATST STASNPSTPN 780
PTVNATPMNN QRSAAEDNAL LKQLLQNNSS SHSLNQISIT SAHVGSASAS APLSARKVIN 840
VRAPSMGKVR SLEDQLARPV IPPVPTATQA AGSSSSSGSV ATSTTTTTVA SGGSSQQVAT 900
ASATALPVSA VAITTPGVGG EAKLEQKSDQ PAAIMQNQSQ NQAPPPPPPP QQQQQQQLHQ 960
PQQLQPSPHQ VKQTVQIVSK ETSFISGPVA AKTLVTEATS KPAELLPPPP YEMATAPISN 1020
VTISISTKQA APKELQMKPK AVAMSLPMEQ GDESLPEQAE PPLHSEQGAT AAGVAPHSGG 1080
PLVSAQWTNN HLEGGVATTK IPFKPGEPQK RKLPMHPQLD EKQIQQQAEI PISTSLPTTP 1140
TGQGTPDKVQ LISAIATYVK KSGVPNEAQP IQNQSQGQVQ MQAQMQATMQ GHLSGQMSGQ 1200
ISGHAAGQIP AQMHLQVQHQ LHMAVHPQQQ QQQLHQNQPQ NATIPLPVTG QGAVPIPVPT 1260
MESKAGDQRK RRKREVQKPR RTNLNAGQAG GALKDLTGPL PAGAMVQLAG MPPGTQYIQG 1320
AASGTGHVIT STGQGVTLGG VGASTGASSS PMLKKRVRKF SKVEEDHDAF TEKLLTHIRQ 1380
MQPLQVLEPH LNRNFHFLIG SNETSGGGSP ASMSSAASAG SSSAGGGKLK GGSRGWPLSR 1440
HLEGLEDCDG TVLGRYGRVN LPGIPSLYDS ERFGGSRGLV GGSARTRSPS PAESPGAEKM 1500
LPMSSIQNDF YDQEFSTHME RNPRERLVRH IGAVKDCNLE TVDLVESEGV AAWATLPRLT 1560
RYPGLILLNG NSRCHGRMSP VALPEDPLTM RFPVSPLLRS CGEELRKTQQ MELGMGPLGN 1620
NNNNNYQQKN QNVILALPAS ASENIAGVLR DLANLLHLAP ALTCKIIEDK IGNKLEDQFM 1680
NQDDEKHVDF KRPLSQVSHG HLRKILNGRR KLCRSCGNVV HATGLRVPRH SVPALEEQLP 1740
RLAQLMDMLP RKSVPPPFVY FCDRACFARF KWNGKDGQAE AASLLLQPAG GSAVKSSNGD 1800
SPGSFCASST APAEMVVKQE PEDEDEKTPS VPGNPTNIPA QRKCIVKCFS ADCFTTDSAP 1860
SGLELDGTAG AGTGAGPVNN TVWETETSGL QLEDTRQCVF CNQRGDGQAD GPSRLLNFDV 1920
DKWVHLNCAL WSNGVYETVS GALMNFQTAL QAGLSQACSA CHQPGATIKC FKSRCNSLYH 1980
LPCAIREECV FYKNKSVHCS VHGHAHAGIT MGAGAGATTG AGLGGSVADN ELSSLVVHRR 2040
VFVDRDENRQ VATVMHYSEL SNLLRVGNMT FLNVGQLLPH QLEAFHTPHY IYPIGYKVSR 2100
YYWCVRRPNR RCRYICSIAE AGCKPEFRIQ VQDAGDKEPE REFRGSSPSA VWQQILQPIT 2160
RLRKVHKWLQ LFPQHISGED LFGLTEPAIV RILESLPGIE TLTDYRFKYG RNPLLEFPLA 2220
INPSGAARTE PKQRQLLVWR KPHTQRTAGS CSTQRMANSA AIAGEVACPY SKQFVHSKSS 2280
QYKKMKQEWR NNVYLARSKI QGLGLYAARD IEKHTMIIEY IGEVIRTEVS EIREKQYESK 2340
NRGIYMFRLD EDRVVDATLS GGLARYINHS CNPNCVTEIV EVDRDVRIII FAKRKIYRGE 2400
ELSYDYKFDI EDESHKIPCA CGAPNCRKWM N 2431
Nucleotide Sequence
(Fasta)		AACACTGCTC TGCATACACG AAAATAAAAT TTTTTTGACT AATCGTGCAT GTTTTCGCTC 60
GGTAAAAAAA AAAGCAGGCC GCGCGAGCCC TAGCTAGCTA GACCGCCGCC CTTCCCGTCC 120
CACGAAACGC AGCGCATCGC ATCCGGCGTT CCGCGTTTCC ACTTGTGTGT TTGTTATGAA 180
TATACCGAAG GTGACAACAT CGCTTGGTGC CGCCGAAAAG GCGAAACCCG AAAGAGTAGC 240
ATCCGTGGCC GCCGCTGCCT TCAATGCGGT CAGCCTGCAG AAGCGCAGCG GCGACGACAC 300
CGCCACTCCG GCGGAGGATC CCACGCGCAA GAAGGCCAAG ACGGAGCTGC TTCTCGGAAC 360
TGGAACGGCA GCGCCCAGTT TGCCCGCCAA AGCGTCGAGC ACCGCGCCGC AGCAGCTCCT 420
CTACCAGCGG AGTGGACAGC AGGCTAAGGC GCAGGTAAAA GCTGCGTCGG AGCCGCAGGA 480
TGTCGAGACG GCGGACGGCG TCTGGGACGC CCGCGATCAG CAGATCATAG TGTGCAACTT 540
CGGCTCCGGC ACTGAGATGG GTGCCATCAA GGCGGAGGAC GCTGACAAGC AGAGTGAGTA 600
CAGAATCAGC ACTCCAAGGA ACAGTCAATC TAACCCTTTG CTACACCGAA ACACAGCCTT 660
TACCAGCTTT ACCAAAAAGG AGGGTGCCTC ATCGTCGGCC TCGTCATCAT CGTCAACCGC 720
GTCCGTCATT TCCATCGAGC CCAGTGGCTC GGGGCAGGAT CATGCTGAAA ACTCCGGCAA 780
ATCTGAGGAC CTCGACTACG TACTGATGCC AGCCAGCGGC GCGGATAGCT CTACATCTGT 840
GGGTAACTCC ACCGGAACGG GAACACCAGC AGGAACGCCT ATTGGAGCTA CTACCTCCAC 900
CATTATTTTA AACGCTAACA ACGGAACGGC AGGAGTCAGT GGAGCCGGCA CCACTACAAT 960
CCTCACACAG AAATCCGGTC ACACGAACTA CAACATCTTC AATACCACGG CCACTGGTAG 1020
CCAAACGCCC ACTACAACAT TGTTAAACCG GGTGAATCTT CACCCCAAGA TGAAAACCCA 1080
GCTGATGGTT AACGCCAAGA AGCTGTCGGA AGTAACGCAG ACCACGGCGA AAGTGTCGAT 1140
TGGCAACAAG ACTATATCGG TGCCGCTGCT CAAGCCGCTG ATGAGCGCTA GTGGAGCGGC 1200
CACAGCCGGA GGAGCCACGA TTGTAGAGAG CAAGCAACTG CTGCAGCCGG GCGGTCAGGT 1260
GACTACCGTA ATGAGTGCTG CGCAGCAAAG CGGTGGTCAG CAGGTCCACC CGCACGTCCA 1320
TTCTCATGCA CATCACAACT TTACCAAACT TATCAAACGC GGGCCAAAAA ATAGCGGCAC 1380
CATTGTCTCG TTTTCGGGGC TACAGATCAA GCCGGCGAAC ACCAAAATTG TGGCCACCAA 1440
GGTGGTGAGC AAAAAGATGC TGCAACTTCA GCAGCACCAA CAACAGATCC AACAGCAGCA 1500
GCAGCTTCAG CAGCTGCAGG TGACCAGTGG TGGAGGCCTG GCTCCGCCCA CAGGCAGCAT 1560
AGTGACTATC ACCACCACCA ACCCCAGCCA AACGTACGCA ATGGTTCAGG ATTCCGCAAC 1620
TGTGGGACCT GCGGCCCATT CGGAAGACGA TGCGCCAGCG CCTCGAAAGA TTACAGCCTA 1680
CTCGGAGAAC CTTCAAAAAA TTCTCAACAA GAGCAAGTCC CAGGAATCGA CTGGAGGCCC 1740
GGAGGAGTTC ACCAACATCA ACAGCGTGGT GATTAAGCCG CTCGACAAGA ATACACTCAA 1800
TTGTCCACCC AGCTTTAACA TCTTTAAGCA GCAGCAGCAC TCACAGGCTG CTCAAAGCCA 1860
ATCAATCTCC GCGGTAGGCA GTGGAGCAGG CACACCCGTG ACGTTTACCA TGGCTTCGGG 1920
GAATGCCTCA GATCTGGCCA CCACCTCCAC CGTTTCCGTT TCGGCGGGGA CCATCTGCAT 1980
AAACAGTCCG ATGATGGGCA CGCGGCCAAT AATCTCCATT CAGAACAAGA ACATATCCCT 2040
GGTGCTGTCC AAGACGACCA TGGCCCAGCA AAAACCGAAG ATGATAACTA CAACCACGTT 2100
GTCCAGTCAG GCGGCGCTGC AGATGCATCA TGCTTTGATT CAGGATTCTA GTGCAGACAA 2160
GGCGGGATCT TCTGCAAACT CCGGATCAGC TACCTCGGGA GCTTCAATGC AGCTGAAACT 2220
AACGACCGCC AATACGCCCA CCAAACTCAG CGTTAGTCTG GCTCCGGACG TAGTCAAGCT 2280
GGAAGAAGTT GGCAGCGAAT CTAAAGCAAA GCTACTGGTC AAACAGGAGG CGGTTGTGAA 2340
GGATAGCACT GGTACTCCGA CCAGTGAGGA GCGGGCTGAG GAGATCGGCA CGCCGGAGAA 2400
GCGTTTGAAC GCCAATGCCA CAATGACGGC TATTAACCAG GTTCAAAATC AGTCCGCCAA 2460
TCAAATTCAA ATGGCCACAT CTACCTCAAC TGCCTCGAAT CCCAGCACAC CCAATCCTAC 2520
AGTGAACGCC ACACCTATGA ACAACCAACG CTCGGCAGCG GAGGATAATG CACTTCTAAA 2580
GCAACTGCTC CAAAACAACA GCAGCAGTCA TAGCCTCAAC CAGATAAGCA TCACTTCGGC 2640
TCACGTTGGT TCCGCCTCAG CTTCGGCACC TCTTTCCGCC CGCAAGGTTA TCAACGTACG 2700
GGCGCCCAGC ATGGGGAAGG TCAGAAGTTT GGAGGATCAA CTGGCACGTC CGGTGATTCC 2760
TCCGGTGCCC ACTGCCACGC AGGCGGCAGG TAGTAGTAGT AGCAGTGGAT CTGTGGCCAC 2820
GTCCACCACC ACCACAACAG TAGCTAGCGG AGGAAGCAGC CAACAGGTAG CCACCGCCTC 2880
AGCGACGGCT CTACCTGTTA GTGCGGTCGC AATTACCACA CCAGGAGTGG GAGGGGAGGC 2940
AAAGCTGGAG CAGAAATCCG ATCAGCCAGC AGCAATTATG CAGAATCAGA GCCAAAACCA 3000
GGCGCCTCCA CCACCACCGC CACCACAGCA GCAGCAGCAG CAGCAACTAC ACCAGCCGCA 3060
GCAGCTGCAA CCGTCACCCC ACCAAGTCAA GCAGACTGTG CAGATTGTGT CGAAGGAGAC 3120
GTCGTTCATC TCAGGACCCG TTGCTGCTAA AACACTAGTG ACGGAAGCCA CTTCGAAGCC 3180
GGCTGAACTA CTACCTCCTC CGCCTTACGA AATGGCCACT GCTCCTATAT CGAACGTCAC 3240
CATATCCATA TCCACCAAAC AAGCGGCTCC GAAGGAACTG CAGATGAAGC CCAAGGCGGT 3300
AGCTATGTCA CTACCCATGG AGCAGGGCGA CGAATCGCTG CCAGAGCAAG CGGAGCCGCC 3360
GCTTCATTCG GAACAGGGAG CTACTGCAGC GGGAGTTGCA CCTCACTCCG GAGGTCCCCT 3420
TGTGTCTGCG CAATGGACCA ATAACCATTT AGAAGGAGGT GTAGCCACCA CAAAGATACC 3480
GTTCAAGCCT GGAGAGCCTC AAAAACGCAA GCTCCCCATG CACCCACAAC TGGACGAAAA 3540
GCAGATCCAG CAACAGGCAG AGATTCCCAT AAGCACCTCC CTACCAACAA CTCCGACTGG 3600
ACAAGGTACT CCCGACAAAG TACAGCTGAT CTCAGCGATT GCCACTTATG TAAAGAAATC 3660
CGGTGTCCCG AACGAGGCAC AACCCATCCA GAACCAGAGC CAGGGCCAGG TGCAGATGCA 3720
GGCGCAAATG CAGGCGACTA TGCAAGGACA CCTGTCTGGG CAGATGTCCG GACAAATCTC 3780
CGGACATGCC GCTGGACAGA TACCCGCTCA AATGCATTTG CAAGTACAGC ATCAGCTCCA 3840
TATGGCAGTT CATCCACAGC AGCAGCAGCA GCAACTGCAC CAGAACCAAC CACAGAATGC 3900
GACGATTCCC CTTCCAGTTA CTGGACAGGG TGCAGTGCCC ATCCCCGTGC CCACCATGGA 3960
GAGCAAGGCA GGCGACCAAA GGAAGCGCCG CAAACGTGAG GTCCAGAAGC CGAGGCGCAC 4020
AAATCTGAAC GCCGGACAAG CGGGTGGAGC TCTTAAGGAT CTAACAGGTC CACTACCGGC 4080
AGGTGCAATG GTCCAACTGG CAGGAATGCC GCCGGGGACC CAGTACATAC AAGGCGCGGC 4140
ATCAGGGACT GGTCATGTGA TCACCAGTAC CGGACAAGGA GTTACTTTGG GAGGAGTGGG 4200
CGCCAGTACT GGAGCCAGTT CCTCGCCCAT GCTCAAGAAG CGGGTTCGCA AGTTCTCCAA 4260
GGTAGAAGAG GATCACGATG CATTTACCGA GAAGTTGCTG ACGCACATCC GCCAAATGCA 4320
GCCGCTTCAA GTTCTGGAGC CGCATCTCAA TCGCAACTTT CACTTTCTTA TCGGGAGCAA 4380
CGAGACTTCT GGAGGTGGTT CGCCCGCCTC AATGAGTTCT GCGGCTTCTG CCGGATCATC 4440
ATCGGCTGGA GGAGGAAAGC TGAAGGGCGG ATCTCGAGGC TGGCCACTGA GCAGGCATTT 4500
GGAAGGTCTG GAGGACTGTG ATGGCACCGT TCTCGGCCGC TATGGTCGAG TGAATCTGCC 4560
AGGGATACCC TCGTTGTACG ATAGCGAACG CTTTGGCGGA AGTAGAGGTC TAGTTGGTGG 4620
ATCTGCACGA ACCCGTTCAC CCTCGCCAGC AGAGTCTCCG GGAGCAGAAA AGATGCTACC 4680
AATGTCTAGC ATCCAAAATG ATTTTTATGA CCAGGAGTTC TCCACGCATA TGGAGCGCAA 4740
TCCTAGGGAA CGCCTGGTGC GGCACATTGG AGCCGTCAAG GATTGCAATT TGGAGACCGT 4800
AGACCTGGTG GAGAGCGAGG GCGTAGCTGC GTGGGCGACT CTTCCACGAC TTACCCGCTA 4860
TCCGGGTCTA ATACTGCTCA ATGGAAACAG CCGTTGCCAT GGACGGATGT CGCCGGTCGC 4920
ACTGCCGGAG GATCCGCTGA CCATGCGCTT TCCCGTGTCT CCACTGCTTC GATCCTGCGG 4980
CGAAGAGCTG CGCAAGACAC AGCAGATGGA GCTGGGAATG GGACCGCTGG GCAATAATAA 5040
TAATAACAAT TACCAGCAGA AGAACCAGAA TGTGATACTC GCACTGCCCG CCTCGGCATC 5100
GGAGAACATA GCCGGCGTGC TGCGGGATCT GGCCAATCTA CTGCACTTGG CGCCCGCCCT 5160
TACCTGCAAG ATCATCGAGG ACAAGATTGG CAACAAGTTG GAGGACCAGT TTATGAATCA 5220
GGACGATGAA AAGCACGTCG ACTTCAAGCG ACCACTGAGT CAAGTGAGTC ACGGTCATCT 5280
GAGGAAGATC CTCAACGGGC GTCGTAAGCT CTGCCGCAGC TGCGGAAATG TGGTTCACGC 5340
CACTGGGCTG CGAGTTCCTC GGCACAGTGT TCCTGCCCTA GAAGAGCAAC TCCCCCGGTT 5400
GGCTCAACTG ATGGACATGC TGCCAAGAAA ATCGGTTCCC CCTCCTTTTG TGTACTTCTG 5460
CGATCGCGCC TGCTTTGCGA GATTCAAGTG GAATGGAAAG GATGGCCAGG CGGAGGCGGC 5520
TAGTCTGCTG CTTCAGCCAG CCGGCGGTTC TGCTGTAAAA TCATCCAACG GAGACTCGCC 5580
TGGCAGCTTC TGCGCCAGCT CAACTGCCCC AGCGGAAATG GTGGTCAAAC AAGAACCGGA 5640
GGACGAGGAT GAGAAAACGC CGAGCGTACC GGGCAACCCC ACAAATATCC CCGCACAGCG 5700
CAAATGCATT GTGAAGTGTT TTAGTGCTGA TTGCTTCACC ACGGACTCGG CGCCATCCGG 5760
ACTGGAGCTC GACGGAACTG CTGGTGCCGG AACTGGGGCT GGACCGGTCA ATAATACTGT 5820
GTGGGAAACA GAGACCAGTG GGCTGCAGTT GGAGGACACG CGGCAGTGTG TCTTCTGCAA 5880
TCAGCGTGGT GACGGCCAGG CAGATGGACC CTCGCGACTG CTTAACTTCG ATGTGGATAA 5940
ATGGGTTCAC CTTAACTGCG CCCTGTGGTC CAACGGCGTG TACGAGACGG TGTCTGGGGC 6000
GCTGATGAAC TTCCAGACAG CTCTGCAAGC GGGACTGAGC CAGGCGTGTA GCGCTTGTCA 6060
CCAACCAGGC GCCACCATCA AGTGTTTCAA GTCGCGCTGC AACAGCCTGT ACCACCTGCC 6120
ATGCGCCATT CGCGAGGAGT GCGTCTTTTA CAAGAACAAG TCCGTGCACT GCAGCGTTCA 6180
TGGTCATGCT CATGCCGGCA TCACGATGGG TGCAGGAGCA GGCGCCACGA CTGGCGCCGG 6240
ATTAGGAGGC TCTGTGGCAG ATAATGAACT GAGCTCCCTG GTTGTCCACC GGAGAGTTTT 6300
TGTCGATCGG GATGAAAACC GTCAGGTGGC CACCGTCATG CACTATTCAG AGCTAAGCAA 6360
CCTGCTCCGT GTGGGCAACA TGACGTTCCT GAACGTGGGT CAGTTACTGC CGCATCAGCT 6420
GGAGGCCTTC CACACACCCC ACTACATCTA CCCCATTGGC TACAAGGTGA GTCGCTACTA 6480
CTGGTGCGTG CGACGACCCA ATCGTAGGTG TCGATACATT TGCAGTATCG CAGAGGCCGG 6540
ATGCAAGCCC GAGTTTCGCA TCCAGGTGCA GGACGCCGGC GACAAGGAGC CGGAGCGCGA 6600
GTTTCGGGGC AGTTCGCCCT CGGCGGTCTG GCAGCAGATT CTGCAGCCAA TCACGCGACT 6660
GCGTAAGGTG CACAAGTGGT TGCAGCTCTT TCCCCAGCAC ATCAGTGGTG AGGACCTATT 6720
TGGCCTAACG GAACCGGCCA TTGTGCGAAT CCTGGAAAGC CTCCCGGGCA TTGAGACGCT 6780
CACTGACTAC CGCTTCAAGT ACGGTCGCAA CCCGCTTCTT GAGTTCCCGC TAGCCATCAA 6840
TCCGTCTGGA GCGGCGCGTA CGGAACCCAA GCAACGACAG CTGCTCGTCT GGAGGAAGCC 6900
GCATACGCAA CGCACGGCCG GCAGCTGCAG CACGCAGCGG ATGGCCAACT CGGCTGCGAT 6960
TGCCGGAGAA GTGGCCTGCC CGTACAGCAA GCAGTTCGTG CATTCGAAGA GCTCCCAGTA 7020
CAAAAAGATG AAGCAGGAGT GGCGCAACAA CGTCTACTTG GCGAGATCTA AGATCCAGGG 7080
TCTTGGCTTG TATGCAGCTC GGGACATTGA AAAGCACACC ATGATAATCG AGTACATTGG 7140
CGAGGTTATC CGCACCGAGG TCTCCGAGAT ACGCGAGAAG CAGTACGAGT CCAAGAACCG 7200
TGGCATCTAC ATGTTCCGGC TGGATGAAGA CCGCGTGGTG GACGCCACTC TAAGCGGCGG 7260
GTTGGCGCGC TACATCAACC ATTCGTGCAA TCCCAACTGT GTTACCGAGA TAGTGGAGGT 7320
CGATCGCGAC GTGCGGATCA TAATATTCGC CAAGCGGAAG ATCTATCGCG GCGAGGAGCT 7380
CTCGTACGAC TACAAGTTCG ACATTGAGGA CGAGTCGCAC AAGATACCGT GCGCCTGTGG 7440
AGCGCCCAAC TGTCGCAAGT GGATGAACTA GAGTCGGGAG GAGCCTCTAG CGGAGGACCA 7500
AAGGAAGCGC AAGAAGCGGC GGCGAGCACG TCGCTCCCAG TGAACAGGAA CAGGAGTAGA 7560
GACAGGAACA GGAACAGGAC TTGTATCTGA TCAAGTAGCT AGATTCGCTA AGCATTATAG 7620
TTCGTGTACA TTTATATATA TATATATATA TATATATATA TATTTATATA TATATAGTTT 7680
ATATGCTATA TGCAGATATG CTCGTGGAGA GCATATGACC TTGTAAGTTT TGTATATGTG 7740
CCCACTGTAG CCAATTCGTA TCCTTTATAT CGCTCTTAAG TGCAAAAGTG GAGAGTGTCT 7800
TCATAGTTTA AATTGAATAA TTGCTATCGT TTCTACATAG AAAGAATATA AATGTTACTG 7860
CTAGGACACG ACCACCCCTG TAATGTATTT CGGACCCCCT CTCCTCACAC AGTCGCTGGA 7920
GCACCTAATT TTATTTGTTT TAGCACCATC TCCACATTCA TCACTACCAC CATTGCAATT 7980
ATCGCGAGGA AACTGACCGC CCCGATGGCC AACCCAAAAC TTGACTTTAT GCGTGTGTGC 8040
CTTCCCCTCT GTTTACCATT ATTATTATTA TCATAATTGT AGCGGTTATC TTTCAATATT 8100
CGGCCACTTT ACATGGGGAG CGATCCTTCT TTCGCTGCGT GTATCGTGCG CAACCTTCTT 8160
TGAATATATA CACTGATAAG GATATGAACA CCTACTTCTA TTTTATTTTA TTTAAATAGT 8220
TTGCGATTAC TTTTAAGTAC ATTAACTAAC TCCGAACAAC GTGTATTTTT CATCCCCTTA 8280
AATAGTAGCT AAGTAAATTT TATGCCACCA TTTT 8315
Sequence Source Ensembl
Keyword

KW-0010--Activator
KW-0025--Alternative splicing
KW-0156--Chromatin regulator
KW-0158--Chromosome
KW-0181--Complete proteome
KW-0217--Developmental protein
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0949--S-adenosyl-L-methionine
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0808--Transferase
--
Interpro

IPR003889--FYrich_C
IPR003888--FYrich_N
IPR015722--Histone-lys_MeTfrase_Trr
IPR003616--Post-SET_dom
IPR001214--SET_dom
PROSITE

PS51543--FYRC
PS51542--FYRN
PS50868--POST_SET
PS50280--SET
Pfam

PF05965--FYRC
PF05964--FYRN
PF00856--SET
Gene Ontology

GO:0044666--C:MLL3/4 complex
GO:0005634--C:nucleus
GO:0005700--C:polytene chromosome
GO:0005703--C:polytene chromosome puff
GO:0042054--F:histone methyltransferase activity
GO:0042800--F:histone methyltransferase activity (H3-K4 specific)
GO:0005102--F:receptor binding
GO:0003713--F:transcription coactivator activity
GO:0048749--P:compound eye development
GO:0051568--P:histone H3-K4 methylation
GO:0016571--P:histone methylation
GO:0035332--P:positive regulation of hippo signaling
GO:1900114--P:positive regulation of histone H3-K9 trimethylation
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0007458--P:progression of morphogenetic furrow involved in compound eye morphogenesis
GO:0035075--P:response to ecdysone
GO:0007224--P:smoothened signaling pathway
GO:0006351--P:transcription, DNA-templated
Orthology
WERAM ID Ensembl Protein ID Species Identity E-value Score
WERAM-Caj-0209 ENSCJAP00000036628.3 Callithrix jacchus 54 4e-178 624
WERAM-Fec-0096 ENSFCAP00000008002.3 Felis catus 54 8e-178 623
WERAM-Nol-0046 ENSNLEP00000005663.2 Nomascus leucogenys 54 2e-177 622
WERAM-Loa-0207 ENSLAFP00000021432.1 Loxodonta africana 54 2e-177 622
WERAM-Caf-0059 ENSCAFP00000007370.4 Canis familiaris 54 2e-177 622
WERAM-Bot-0193 ENSBTAP00000028347.5 Bos taurus 54 2e-177 621
WERAM-Mup-0098 ENSMPUP00000009152.1 Mustela putorius furo 54 2e-177 621
WERAM-Aim-0154 ENSAMEP00000014067.1 Ailuropoda melanoleuca 54 3e-177 621
WERAM-Hos-0018 ENSP00000347325.3 Homo sapiens 54 4e-177 620
WERAM-Ict-0124 ENSSTOP00000012342.2 Ictidomys tridecemlineatus 54 4e-177 620
WERAM-Gog-0210 ENSGGOP00000027941.1 Gorilla gorilla 54 5e-177 620
WERAM-Chs-0076 ENSCSAP00000002864.1 Chlorocebus sabaeus 54 6e-177 620
WERAM-Paa-0005 ENSPANP00000006150.1 Papio anubis 54 7e-177 620
WERAM-Orc-0115 ENSOCUP00000009766.3 Oryctolagus cuniculus 54 8e-177 620
WERAM-Pat-0168 ENSPTRP00000046674.3 Pan troglodytes 54 8e-177 620
WERAM-Mod-0039 ENSMODP00000005827.3 Monodelphis domestica 54 1e-176 619
WERAM-Anp-0025 ENSAPLP00000003226.1 Anas platyrhynchos 54 2e-176 619
WERAM-Fia-0086 ENSFALP00000007141.1 Ficedula albicollis 54 2e-176 618
WERAM-Ora-0065 ENSOANP00000009850.3 Ornithorhynchus anatinus 54 2e-176 618
WERAM-Gaga-0065 ENSGALP00000010110.4 Gallus gallus 54 3e-176 618
WERAM-Tas-0126 ENSTSYP00000013377.1 Tarsius syrichta 54 4e-176 617
WERAM-Tag-0008 ENSTGUP00000000641.1 Taeniopygia guttata 54 4e-176 617
WERAM-Mum-0152 ENSMUSP00000043874.7 Mus musculus 54 5e-176 617
WERAM-Myl-0122 ENSMLUP00000010086.2 Myotis lucifugus 53 1e-175 616
WERAM-Sah-0130 ENSSHAP00000013860.1 Sarcophilus harrisii 54 1e-175 615
WERAM-Cap-0018 ENSCPOP00000001682.2 Cavia porcellus 54 2e-175 615
WERAM-Sus-0158 ENSSSCP00000023447.1 Sus scrofa 54 3e-175 614
WERAM-Prc-0090 ENSPCAP00000008256.1 Procavia capensis 54 4e-175 614
WERAM-Leo-0127 ENSLOCP00000015481.1 Lepisosteus oculatus 54 7e-175 613
WERAM-Pes-0170 ENSPSIP00000020005.1 Pelodiscus sinensis 54 1e-174 613
WERAM-Eqc-0178 ENSECAP00000019090.1 Equus caballus 54 6e-174 610
WERAM-Otg-0226 ENSOGAP00000016765.1 Otolemur garnettii 53 2e-173 608
WERAM-Tut-0057 ENSTTRP00000004493.1 Tursiops truncatus 52 3e-173 608
WERAM-Dar-0080 ENSDARP00000053862.6 Danio rerio 51 1e-172 606
WERAM-Ova-0206 ENSOARP00000020382.1 Ovis aries 52 3e-172 605
WERAM-Dan-0166 ENSDNOP00000021359.1 Dasypus novemcinctus 52 4e-172 604
WERAM-Poa-0043 ENSPPYP00000005112.2 Pongo abelii 52 5e-172 603
WERAM-Lac-0079 ENSLACP00000010253.1 Latimeria chalumnae 53 6e-172 603
WERAM-Xet-0065 ENSXETP00000021458.2 Xenopus tropicalis 53 6e-172 603
WERAM-Mae-0064 ENSMEUP00000005938.1 Macropus eugenii 52 4e-171 601
WERAM-Asm-0054 ENSAMXP00000006762.1 Astyanax mexicanus 54 2e-170 598
WERAM-Tar-0144 ENSTRUP00000031120.1 Takifugu rubripes 51 7e-170 597
WERAM-Anc-0164 ENSACAP00000015233.2 Anolis carolinensis 52 8e-170 596
WERAM-Xim-0135 ENSXMAP00000011152.1 Xiphophorus maculatus 51 2e-169 595
WERAM-Ten-0184 ENSTNIP00000018122.1 Tetraodon nigroviridis 52 5e-169 593
WERAM-Pof-0076 ENSPFOP00000007738.1 Poecilia formosa 51 8e-169 593
WERAM-Ptv-0040 ENSPVAP00000004387.1 Pteropus vampyrus 52 1e-168 593
WERAM-Orn-0146 ENSONIP00000015272.1 Oreochromis niloticus 51 1e-168 593
WERAM-Orla-0036 ENSORLP00000004819.1 Oryzias latipes 52 1e-167 589
WERAM-Gaa-0092 ENSGACP00000011950.1 Gasterosteus aculeatus 50 2e-166 585
WERAM-Pem-0016 ENSPMAP00000002311.1 Petromyzon marinus 51 3e-166 585
WERAM-Gam-0044 ENSGMOP00000004922.1 Gadus morhua 50 5e-164 577
WERAM-Dio-0019 ENSDORP00000002189.1 Dipodomys ordii 51 9e-155 546
WERAM-Ran-0263 ENSRNOP00000069442.1 Rattus norvegicus 50 1e-154 546
WERAM-Cii-0007 ENSCINP00000003156.3 Ciona intestinalis 49 6e-150 530
WERAM-Ect-0018 ENSETEP00000001138.1 Echinops telfairi 50 1e-144 513
WERAM-Meg-0048 ENSMGAP00000004625.2 Meleagris gallopavo 51 3e-136 484
WERAM-Mam-0144 ENSMMUP00000020643.2 Macaca mulatta 49 2e-135 483
WERAM-Cis-0001 ENSCSAVP00000000096.1 Ciona savignyi 44 2e-126 452
WERAM-Mim-0010 ENSMICP00000000977.1 Microcebus murinus 58 2e-124 446
WERAM-Ocp-0133 ENSOPRP00000014011.2 Ochotona princeps 46 2e-115 416
WERAM-Vip-0002 ENSVPAP00000000152.1 Vicugna pacos 59 5e-98 358
WERAM-Chh-0008 ENSCHOP00000000593.1 Choloepus hoffmanni 57 3e-63 243
WERAM-Cae-0045 T12D8.1 Caenorhabditis elegans 34 9e-56 218
WERAM-Soa-0133 ENSSARP00000013142.1 Sorex araneus 38 3e-47 189
WERAM-Tub-0079 ENSTBEP00000009516.1 Tupaia belangeri 38 2e-46 187
WERAM-Ere-0115 ENSEEUP00000012211.1 Erinaceus europaeus 35 2e-45 183
WERAM-Cym-0008 CMD005CT Cyanidioschyzon merolae 28 4e-45 182
WERAM-Php-0016 PP1S133_30V6.1 Physcomitrella patens 53 2e-36 154
WERAM-Ors-0112 OS12T0613200-02 Oryza sativa 53 3e-36 153
WERAM-Org-0116 ORGLA12G0159200.1 Oryza glaberrima 53 3e-36 153
WERAM-Sei-0078 Si021071m Setaria italica 53 4e-36 152
WERAM-Orbr-0114 OB09G25870.1 Oryza brachyantha 38 1e-35 150
Created Date 25-Jun-2016