WERAM Information

Tag Content
WERAM ID WERAM-Ran-0028
Ensembl Protein ID ENSRNOP00000071341.1
Uniprot Accession A0A0G2K082; A0A0G2K082_RAT
Genbank Protein ID
Protein Name Histone deacetylase
Genbank Nucleotide ID
Gene Name HDAC9
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSRNOG00000004158.7 ENSRNOT00000086038.1 ENSRNOP00000071341.1
ENSRNOG00000004158.7 ENSRNOT00000005521.7 ENSRNOP00000005521.6
Details
Type Family Domain Substrates AA References (PMIDs)
HDAC Class-II Hist_deacetyl H2A; H2B; H3; H4 K 26395029; 26365275
Status Reviewed
Classification
Type Family E-value Score Start End
HDAC Class-II 1.40e-124 416 49 943
HDAC Class-I 2.30e-31 110 48 946
Organism Rattus norvegicus
NCBI Taxa ID 10116
Functional Description
(View)		 Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.
Domain Profile
  HDAC Class-II
           class-2.txt 33 ilsrlqeagllekleelkarkatkeelqlvHseehvelletaeklekeele 83
                           l  +q+++ ++k + +++ ++++e+l+  H++++ e+++ +++l   + +
  ENSRNOP00000071341.1 49 ELLLIQQQQQIQKQLLIAEFQKQHENLTRQHQAQLQEHIKLQQELLAIKQQ 99
                          444566666666666777777777777777766666666555543332222 PP
           class-2.txt   2 aglvydekmlkhqaleenkekhpEkpeRiqailsrlqeagllekleelkarkatkeelqlvHseehvelletaeklekeeles...... 84 
                           +g+ yd  mlkhq++++n+++hpE+++Riq+i+srlqe+gll+k+e++++rka++ee+qlvHse+h  l++t+ +l+ ++l+       
  ENSRNOP00000071341.1 635 TGIAYDCLMLKHQCICGNSTTHPEHAGRIQSIWSRLQETGLLNKCERIQGRKASLEEIQLVHSEHHSLLYGTS-PLDGQKLDPrtllgd 722
                           7899********************************************************************9.********99***** PP
           class-2.txt  85 .............ltvdsdsiylesksikaarlavGavlelvdkvlkgelkngfavvRPPGHHaeestamGFClfnnvavaakllqqkl 160
                                        l+vdsd+i++e +s+ aar+avG+v+el++kv++gelkngfavvRPPGHHaees+amGFC+fn+va++ak+l+++l
  ENSRNOP00000071341.1 723 dsrkffsslpcggLGVDSDTIWNELHSSGAARMAVGCVIELASKVASGELKNGFAVVRPPGHHAEESAAMGFCFFNSVAITAKYLRDQL 811
                           ***************************************************************************************** PP
           class-2.txt 161 kvkkilivDwDvHhGnGtqeifykdpkvlylSlHRydkgsffpesgsgavdevgegkgegfnvNvawnggl...mgdaeylaafrevvl 246
                           +++kilivD+DvHhGnGtq++fy dp++ly+SlHRyd+g+ffp  gsga++evg g geg+nvN+aw+ggl   mgd eyl afr+vv+
  ENSRNOP00000071341.1 812 NISKILIVDLDVHHGNGTQQAFYADPSILYISLHRYDEGNFFP--GSGAPNEVGVGLGEGYNVNIAWTGGLdppMGDVEYLEAFRTVVM 898
                           *******************************************..******************************************** PP
           class-2.txt 247 piakeFkPdlvlvsaGfDaaeg..dplgglsvtakcyatltkqllk 290
                           p+a+eF+Pd+vlvsaGfDa eg   plgg++vtakc ++l ++++k
  ENSRNOP00000071341.1 899 PVAREFDPDMVLVSAGFDALEGhtPPLGGYKVTAKC-KYLFQDFMK 943
                           **********************9889**********.667777665 PP
  HDAC Class-I
           class-1.txt 18 qkhpmkpkrlsltheLvlnyglskkleivkpkkasaeellkfhse 62
                          q+   ++++ ++ ++L+++   +++ ++++ ++a+ +e +k ++e
  ENSRNOP00000071341.1 48 QELLLIQQQQQIQKQLLIAEFQKQHENLTRQHQAQLQEHIKLQQE 92
                          444444555555555555555555555566666666665555543 PP
           class-1.txt  20 hpmkpkrlsltheLvlnyglskkleivkpkkasaeellkfhseeyieflkkvepenae............elskelkkfnvgedc.Pvf 95 
                           hp    r++ + + + + gl +k e+++ +kas ee++ +hse++  +  ++  + ++            ++ ++l   ++g d+  + 
  ENSRNOP00000071341.1 656 HPEHAGRIQSIWSRLQETGLLNKCERIQGRKASLEEIQLVHSEHHSLLYGTSPLDGQKldprtllgddsrKFFSSLPCGGLGVDSdTIW 744
                           66666666666666677777777777777777777777777665543333333333334444444443333333333334555542366 PP
           class-1.txt  96 dglfey..cqlitGasleaakkLnkkead..iainwaGGlhhakkseasGfcyvnDivlailellk..khkrvlyididlhhGDgveea 178
                           ++l++   +++  G  +e a+k+ ++e +   a+    G hha  s a Gfc+ n + ++   l+   + +++l +d+d+hhG+g ++a
  ENSRNOP00000071341.1 745 NELHSSgaARMAVGCVIELASKVASGELKngFAVVRPPG-HHAEESAAMGFCFFNSVAITAKYLRDqlNISKILIVDLDVHHGNGTQQA 832
                           777654225677899999999999887661245554444.************************9944567****************** PP
           class-1.txt 179 fyttdrvmtvsfhkyge.effPgtGdlsdvgaekgkyyavnvPlkdgid....DesyekifksviskvieafePeavvlqcGaDslagD 262
                           fy+   ++ +s+h+y+e +ffPg+G  ++vg++ g  y vn+  + g+d    D +y + f++v+ +v + f+P++v++  G D+l g 
  ENSRNOP00000071341.1 833 FYADPSILYISLHRYDEgNFFPGSGAPNEVGVGLGEGYNVNIAWTGGLDppmgDVEYLEAFRTVVMPVAREFDPDMVLVSAGFDALEGH 921
                           ***************8746***********************998887655559********************************976 PP
           class-1.txt 263 ..rlgefnlsikghaecvkfvksfn 285
                             +lg ++++ k +    +f+k ++
  ENSRNOP00000071341.1 922 tpPLGGYKVTAKCKYLFQDFMKCYD 946
                           337*******999999999999885 PP
Protein Sequence
(Fasta)		MHSMISSVDV KSEVPMGLEP ISPLDLRTDL RMMMPVVDPV VREKQLQQEL LLIQQQQQIQ 60
KQLLIAEFQK QHENLTRQHQ AQLQEHIKLQ QELLAIKQQQ ELLEKEQKLE QQRQEQEVER 120
HRREQQLPPL RGKDRGRERA VASTEVKQKL QEFLLSKSAT KDTPTNGKNH SVGRHPKLWY 180
TAAHHTSLDQ SSPPLSGTSP SYKYTLPGAQ DTKDDFPLRK TASEPNLKVR SRLKQKVAER 240
RSSPLLRRKD GNLVTSFKKR VFEVAESSVS SSSPGSGPSS PNNGPAGNVT ENEASVLPPT 300
PHPEQLVPQQ RILIHEDSMN LLSLYTSPSL PNITLGLPAV PSPLSASNSL KDKQKCETQM 360
LRQGVPLPGQ YGSGIAASSS HAHVAMEGKP NSSHQALLQH LLLKEQMRQQ KLLVAGGVPL 420
HPQSPLATKE RISPGIRGTH KLPRHRPLNR TQSAPLPQST LAQLVIQQQH QQFLEKQKQY 480
QQQIHMNKLL SKSIEQLKQP GSHLEEAEEE LQGDQAMEER ATSKDSGTGK DSSACVEDTL 540
GQVGAVKVKE EPVDSDEDAQ MQEMECGEQA AFMQQTPLLE SSHTRALSVH QARLAAAGID 600
GLEKHGLLSR THSSPAPSMS PHPAADCPRQ PASATGIAYD CLMLKHQCIC GNSTTHPEHA 660
GRIQSIWSRL QETGLLNKCE RIQGRKASLE EIQLVHSEHH SLLYGTSPLD GQKLDPRTLL 720
GDDSRKFFSS LPCGGLGVDS DTIWNELHSS GAARMAVGCV IELASKVASG ELKNGFAVVR 780
PPGHHAEESA AMGFCFFNSV AITAKYLRDQ LNISKILIVD LDVHHGNGTQ QAFYADPSIL 840
YISLHRYDEG NFFPGSGAPN EVGVGLGEGY NVNIAWTGGL DPPMGDVEYL EAFRTVVMPV 900
AREFDPDMVL VSAGFDALEG HTPPLGGYKV TAKCKYLFQD FMKCYDAIHH LEL 953
Nucleotide Sequence
(Fasta)		GGAACTTAAA GAGAAGGGTG ATAGAGATGT GGAGACAAAT TGATGATCCC AGATTTTCAG 60
ACGTGGAGAC AAATTGATGA TCCCAGATTT TCAAGTCCAA ATATAAGGAC CCACCATAGC 120
CAGAGCACTC TCAAGATTAA TACATGATGG AGTGGCCGGA CGGGAGCAGC TCTTGGCTCA 180
GCAAAGAATG CACAGTATGA TCAGCTCAGT GGACGTGAAA TCAGAGGTTC CTATGGGACT 240
GGAGCCCATC TCACCTTTAG ACCTAAGGAC AGACCTCAGG ATGATGATGC CTGTGGTGGA 300
TCCTGTCGTC CGCGAGAAGC AACTGCAGCA AGAGTTACTT CTTATCCAAC AGCAGCAGCA 360
AATCCAGAAG CAGCTCCTGA TAGCCGAGTT TCAGAAGCAG CACGAGAATT TGACAAGGCA 420
GCATCAAGCA CAACTTCAGG AGCACATCAA GTTACAACAG GAACTTCTAG CCATAAAACA 480
ACAGCAAGAA CTCCTAGAAA AGGAGCAGAA ACTGGAGCAG CAGAGGCAAG AACAGGAAGT 540
AGAGAGGCAT CGCAGAGAGC AGCAGCTTCC TCCTCTCAGA GGCAAAGATA GAGGACGAGA 600
AAGGGCGGTG GCAAGCACAG AGGTTAAGCA GAAGCTTCAA GAATTCCTAT TGAGTAAATC 660
AGCAACGAAA GACACTCCAA CCAATGGAAA GAATCATTCC GTGGGCCGCC ATCCCAAGCT 720
CTGGTACACG GCTGCCCACC ACACATCACT GGATCAAAGC TCTCCACCCC TCAGTGGAAC 780
GTCTCCATCC TACAAATACA CATTACCAGG AGCCCAAGAT ACCAAGGATG ATTTCCCCTT 840
GCGAAAAACA GCCTCAGAGC CCAACTTGAA GGTGCGGTCC AGGTTAAAAC AGAAAGTGGC 900
AGAGAGGAGA AGCAGCCCCT TACTCAGGCG GAAGGATGGA AATCTTGTCA CTTCATTCAA 960
GAAGCGAGTG TTTGAGGTGG CAGAATCCTC GGTCAGTAGC AGCTCTCCAG GGTCAGGTCC 1020
CAGTTCACCA AACAATGGGC CTGCTGGAAA TGTTACCGAA AACGAGGCTT CAGTTCTGCC 1080
TCCCACGCCT CACCCCGAGC AGCTGGTTCC ACAGCAGCGC ATTCTGATTC ACGAAGATTC 1140
CATGAACCTG CTGAGTCTCT ACACCTCCCC GTCCCTGCCC AATATCACCC TGGGACTTCC 1200
AGCAGTGCCA TCCCCACTCA GTGCTTCTAA TTCCCTCAAA GACAAGCAGA AGTGTGAGAC 1260
ACAGATGCTC AGACAAGGTG TCCCTCTGCC CGGCCAGTAT GGAAGTGGCA TTGCAGCATC 1320
CTCCAGCCAT GCTCATGTAG CAATGGAGGG CAAACCGAAC AGCAGTCACC AAGCTCTCCT 1380
GCAGCACCTC CTGCTGAAGG AACAAATGAG ACAGCAAAAG CTTCTTGTGG CTGGTGGAGT 1440
TCCATTACAC CCCCAGTCTC CTTTGGCAAC AAAAGAAAGA ATTTCACCAG GCATTAGAGG 1500
TACCCACAAA TTGCCCCGCC ACAGACCCCT CAATCGAACT CAGTCTGCAC CTTTGCCTCA 1560
GAGCACGCTG GCTCAGCTGG TCATTCAGCA GCAGCACCAG CAGTTCCTGG AGAAGCAGAA 1620
GCAATACCAG CAGCAGATCC ACATGAACAA ACTGCTATCG AAATCTATTG AGCAACTGAA 1680
GCAACCAGGC AGCCATCTTG AAGAGGCAGA GGAGGAGCTT CAGGGGGACC AAGCCATGGA 1740
AGAGAGAGCA ACGTCTAAGG ACAGCGGTAC CGGGAAGGAC AGCAGTGCTT GTGTGGAGGA 1800
CACACTGGGA CAAGTTGGGG CTGTGAAGGT CAAGGAGGAA CCCGTGGACA GCGACGAAGA 1860
TGCTCAGATG CAGGAAATGG AATGTGGGGA GCAGGCTGCT TTTATGCAAC AGACGCCCTT 1920
GCTGGAGTCC TCACACACGC GTGCACTCTC AGTGCACCAG GCTCGGCTGG CTGCAGCTGG 1980
CATCGATGGA TTAGAGAAAC ATGGACTCCT CTCCAGGACC CATTCTTCTC CTGCACCCTC 2040
CATGTCACCT CACCCAGCCG CAGACTGTCC CCGCCAGCCT GCCTCTGCCA CTGGAATTGC 2100
CTATGACTGT CTGATGCTGA AACACCAGTG CATCTGTGGC AATTCCACCA CCCACCCTGA 2160
GCATGCTGGG CGAATACAGA GCATCTGGTC ACGGCTGCAA GAAACCGGGC TGCTAAATAA 2220
ATGTGAGCGA ATTCAAGGTC GAAAAGCCAG CCTGGAGGAA ATTCAGCTTG TTCATTCTGA 2280
ACATCACTCA CTACTGTATG GCACCAGCCC CCTGGACGGA CAGAAGCTGG ACCCCAGGAC 2340
ACTCCTAGGT GATGATTCTC GAAAATTCTT TTCCTCGTTA CCTTGTGGTG GACTCGGGGT 2400
GGACAGTGAC ACCATTTGGA ATGAGCTGCA CTCGTCCGGT GCTGCACGCA TGGCTGTTGG 2460
CTGTGTCATT GAGCTGGCTT CCAAAGTGGC CTCAGGAGAG CTGAAGAATG GGTTTGCTGT 2520
TGTGAGGCCC CCAGGCCATC ATGCTGAAGA ATCTGCAGCC ATGGGGTTCT GCTTTTTTAA 2580
TTCAGTCGCA ATTACGGCCA AATACTTGAG AGACCAACTA AATATAAGCA AGATATTGAT 2640
CGTAGATCTG GATGTTCACC ATGGAAACGG TACACAGCAG GCCTTTTATG CTGACCCCAG 2700
CATCCTGTAC ATTTCACTCC ATCGCTATGA TGAAGGGAAC TTTTTCCCTG GCAGTGGCGC 2760
CCCGAATGAG GTTGGAGTAG GTCTGGGAGA AGGCTACAAT GTAAACATTG CCTGGACAGG 2820
CGGCCTTGAC CCCCCTATGG GAGATGTTGA GTACCTTGAA GCATTCAGGA CTGTCGTGAT 2880
GCCTGTGGCC AGAGAGTTTG ATCCAGACAT GGTCCTGGTT TCTGCTGGAT TTGATGCATT 2940
GGAAGGCCAC ACCCCTCCCC TAGGGGGTTA CAAAGTGACA GCAAAATGCA AGTATCTCTT 3000
TCAGGACTTC ATGAAATGCT ATGACGCCAT ACACCATTTA GAGCTTTAAG ATGCATACTA 3060
CCTTTTACGT GAGTTCAGTA AGCTTTGGGG GAGACGTTTG AAAGTGATTG GCATGGTATT 3120
TCTTGCTCTG TCTGTTTCTT GTCTCTGGAG AAATTTTCAC TGAAGAAAAG CAAAATGGTT 3180
TCCTATGGTG GACGTGATAG GCATATCGGA ACCTTCATGT ATTTTAGGAG TCTTAGTTTT 3240
CTTTTAAAGA CTAAAATGGT ATGACTTCCG TTTACGTTAC GTCTACTGAT CTGAGAACTC 3300
CGAAGTCTAG AGGAGCTACT GAGCTTTTCG CGAGGAGAAC GCAGTTGCTG CCTTTAGTGT 3360
ATTGGACATG GGGTGGGAAT AGACACTTGG CAACGATGTT CGGTTCGGGT TCAAATACAG 3420
ACTTGGTGGT GCTTCAGCAA TCCCAAGGGT CTCCGGGGTC AATGCTGCTC CTCTGCTGGT 3480
TGCAGAGACA AATTTTCTGG CTGCGTTCCA TAGCAGCCCG CTACCCAACA ACGAAACCAA 3540
ATTTCTGTTT CATTTCATTT GAAGACGATG GCACCATGGA ACTTAGCTTG AAAGGATCTT 3600
CTTTAAGAAC AATGTCTTGC TCTGTTATAA AAGCAAAGCC CATCTACAGT CCAAGCATAG 3660
AAATATACAT TGGCACCGTG TGTACCTACT ACGCAAGGAA AAACACGGTA AAACTGCACA 3720
GTGGATGGTA TCCAGTATGG TATGTTTCAG AGGTGGGGGC AGGGGTTAAG GAAGGCAAAC 3780
AACTCAAACA ACTCAAGCTG CTTTAAGTGG GAGAGACGAG CTTGGAGTGA ATGTGCTATA 3840
TTAATTTGAA AAGAGCCAAA GACAGAGATC CATGCCAACC TTTGTTTTGA GCTGGCTGCT 3900
CATGTGAGGG CATTTCTGCA CTCTAATTGT TCCAGTAACA TTGTTAGGTA GTGGCTATTT 3960
TTAACCTCCA TTATTTACCT AGGATTCTTG GTGCCTTGTT GTCTATGGAA AGCATATTGA 4020
AGCAGGCAAC TCCGCGCAAA CAATAAAATA TAGATAATGC ACAACTTTGC TGAAATTGAA 4080
TACAGAGGCA TTTTCTTGTA TTAAATATCT TTAGGGTTCT TCTGGTGATG TTGCTCTCAG 4140
AGGTTCCCTC AAATAAAAGC CATTCTTCCG GTTGCAGATA AGCCTCATTT GAGGCAAGGC 4200
TGCTGACTAG TTTATTTTGA ATAAAGAAAC TCAAATGATA CAAGACACAG GGAGAGAAAC 4260
AGAGAAATAA TGGAAAGAGG CCCTTCTCAT TAAACCCACA CAGCTCCCTC TGGAGTAGGA 4320
AAAATGCTGG GCCTTGAGTC CTTTTTTTAT TCTTGCCATG AGGTGGAGGG GGTTTAACAT 4380
GTCCATCTTT CAAAAATAGA AGGGACTAAT CATTGTGTTC AATTTTGAAA AATTAGTTTA 4440
AATCTCCAAT ATCACATTGA AAAGTAGAAT AAAAAAATAA CAGCAATGTG GTCTCTTCTG 4500
GTTCTAACAC TTCCTTTTTA GTGCCAGTCA GCTTTCACTG CTGTAATAAA ATGGCCGTGA 4560
TAGACAGCTT ATACAGTAGG TCGGGAAGGC TTGTCTCAGG TGACAGTGTT TGAGGTTGTA 4620
GTCCTTGGGA CTGTTGTTGG GAACCCGTGG TGAAGCTGTA CATATGGCGG GGAAACAAGT 4680
GGCAGAGTAC AACTGTTTAT CTCATTGAAA GTGACAGAAA GGATGGAAGG CAGGTTGGGG 4740
ATTTGGCTCA GTGGTAGAGC GCTTGCCTAG CAAGCAGAAG GCCCTGGGTT CAGTCCCCAG 4800
CTCCAAAAAA AAAAAAAAAA AAAAAGGATG GAAGGCACAA AGCCGGTATA ATTCTTTTCA 4860
AGAGTGTGTC TTCAGTGACC TAAAAGCCTT CTATAGGCCC CGCCTTTTAA AACTCCACCT 4920
CTTCCCTATA CTTCATCCTC AGGACGTCAG ACCCAAGTTC TCTCAAACAG GAAGCAATGA 4980
AGCCTTCAAC ACTTGGAATT TACTAATACA GCTGGATTTA TATAGGGTAC ATTTTCCTTT 5040
TCTAGCTCCC AAATAAATTT GAACATAGAA CCTTCTAGCT TTCCTCTTCT TCTGCTCAAG 5100
AAGACATGTG CTTCTCTGCC AGTGTTTATT ACCTAACAGA AGCAGGCACA CCTGAGGTCA 5160
TCAATATTTA ACAATTACTC ATTGGCCAAC TCTTTGCTAT TAATTAAGGA AAACACACAA 5220
TCAGGAGAGG GGATCTCAGA ATGCAGAGTA CAGGAGAGGA TGTCCTGAAT TGTTGATGGA 5280
TTTCATAACT GGGATTAAAA CAAAGTGTTT ATGGACTTGT ACTTGCTTTA AATTAAATGA 5340
GCCACACACT GATTTCTTCT TGCTGAGGAA AAAAATTATC TAGTAATATA CAAAAATGAT 5400
TGAAATGTGC ATTCAGAAGC TCATAATGGG GCCCGAACCC ACAAATACCA TCTGGGATAA 5460
CATGAACCCC AGCACCCACC TCTGAACAGC GGCATGTATC ATCTTAGGGA GGCTTCAGTC 5520
TGCTGGCTGT TTTCGCTATA GAAGTCAACA CCTTAACTGT GGGACCTGGG ATTGCTGCAA 5580
AGCCTTCCAG AGATTCCCTG CTGCCTCTGT ACTGGCTGGC TGCATGCAGA TGCAGTTCCC 5640
TTCAGCTTGA CAGACGGGCG ATTAAAATTG AGATCCCAGT TCTCCATGCC AGACGTCATC 5700
CTCCAAGTGT GGATCCCAGA ATAAAGTTGA AAATGGGGTA CAAATTTGAA GTAAATTGTC 5760
ACTAAACCAT ATGAAAACAA ATGTTCGACT AAACTTTTTT CTATTCTGGC TAAACTCATT 5820
CTTGCTCGAA GTAAAATCCT GGACGATTGG ATCTGAGGGC TGTTTTGAGG ATACTATCAT 5880
TTCAGACATC TGAAAATTTA ATTCCTTGGC ACATCAAATT GAATTTTTAC AGTACTTTAC 5940
TTTGTACTTT TGAAAAGAAA AGAACGATCA AGTCAAAACG ACAATGGATT TTGTTCATTT 6000
TAAACATCTA AATAGCTGCC CGACTCTAAA AGAAAAAAAG AAAGAAAGGC TGGTTCGACA 6060
TCAAAAGTTT CATCCTAAAT ACAGAGAGTT GATTTTACGT TAGAGAGGAT TCCCAACCAG 6120
GACTGTTTTC TTCTTCATTT TTTTTTTGTT ATACCTATGA AAATACAACA TGGTTTGGTT 6180
TGTGCTACAT TTGAAAATGT TGTTTCAAAA TGGAGTTTAT AGGTTTTTAT TTGGAATTTA 6240
TATTCTTAAA TCCAGAGCCA AGGTTAAGTT CCATCTAAGA AAGCAGAATA CTTTGCTCTA 6300
AGCCCAGAAC CCAATGTGGC CTTGAAATTA TCCATTTATC TTTCTAAATA TTCTGGTTCA 6360
TGTCCAACTG TCTTTGTGTT ATAGCTTAAG AAGTTTATAT ATATATATAT ATATATATGT 6420
ATAGGTATAT AGGTGTA 6438
Sequence Source Ensembl
Keyword

KW-0156--Chromatin regulator
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0678--Repressor
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
--
Interpro

IPR000286--His_deacetylse
IPR023801--His_deacetylse_dom
IPR024643--Hist_deacetylase_Gln_rich_N
IPR017320--Histone_deAcase_II_euk
PROSITE
Pfam

PF12203--HDAC4_Gln
PF00850--Hist_deacetyl
Gene Ontology

GO:0000118--C:histone deacetylase complex
GO:0046872--F:metal ion binding
GO:0032041--F:NAD-dependent histone deacetylase activity (H3-K14 specific)
GO:0008134--F:transcription factor binding
GO:0030182--P:neuron differentiation
GO:0006355--P:regulation of transcription, DNA-templated
GO:0001975--P:response to amphetamine
GO:0006351--P:transcription, DNA-templated
Orthology
WERAM ID Ensembl Protein ID Species Identity E-value Score
WERAM-Caf-0031 ENSCAFP00000003650.3 Canis familiaris 92 0.0 1456
WERAM-Aim-0096 ENSAMEP00000008994.1 Ailuropoda melanoleuca 92 0.0 1453
WERAM-Mup-0161 ENSMPUP00000013847.1 Mustela putorius furo 92 0.0 1452
WERAM-Nol-0183 ENSNLEP00000020216.1 Nomascus leucogenys 92 0.0 1449
WERAM-Pat-0158 ENSPTRP00000032389.5 Pan troglodytes 92 0.0 1449
WERAM-Eqc-0153 ENSECAP00000016533.1 Equus caballus 88 0.0 1445
WERAM-Mam-0095 ENSMMUP00000014626.2 Macaca mulatta 89 0.0 1444
WERAM-Hos-0016 ENSP00000410337.2 Homo sapiens 89 0.0 1443
WERAM-Caj-0009 ENSCJAP00000001947.2 Callithrix jacchus 91 0.0 1431
WERAM-Loa-0142 ENSLAFP00000012719.4 Loxodonta africana 91 0.0 1418
WERAM-Poa-0162 ENSPPYP00000019901.2 Pongo abelii 91 0.0 1414
WERAM-Orc-0142 ENSOCUP00000012429.3 Oryctolagus cuniculus 90 0.0 1409
WERAM-Tas-0117 ENSTSYP00000012457.1 Tarsius syrichta 86 0.0 1391
WERAM-Cap-0062 ENSCPOP00000004924.2 Cavia porcellus 89 0.0 1376
WERAM-Paa-0166 ENSPANP00000002081.1 Papio anubis 88 0.0 1343
WERAM-Bot-0044 ENSBTAP00000004971.5 Bos taurus 87 0.0 1335
WERAM-Ict-0021 ENSSTOP00000001380.2 Ictidomys tridecemlineatus 89 0.0 1335
WERAM-Gog-0153 ENSGGOP00000013334.2 Gorilla gorilla 88 0.0 1335
WERAM-Ova-0102 ENSOARP00000010345.1 Ovis aries 87 0.0 1334
WERAM-Tut-0166 ENSTTRP00000014151.1 Tursiops truncatus 83 0.0 1312
WERAM-Pes-0105 ENSPSIP00000013270.1 Pelodiscus sinensis 85 0.0 1281
WERAM-Ocp-0153 ENSOPRP00000015747.2 Ochotona princeps 82 0.0 1281
WERAM-Gaga-0107 ENSGALP00000017619.4 Gallus gallus 82 0.0 1273
WERAM-Soa-0055 ENSSARP00000005400.1 Sorex araneus 84 0.0 1265
WERAM-Ere-0042 ENSEEUP00000003697.1 Erinaceus europaeus 85 0.0 1258
WERAM-Fia-0119 ENSFALP00000010264.1 Ficedula albicollis 82 0.0 1253
WERAM-Mod-0016 ENSMODP00000001749.3 Monodelphis domestica 82 0.0 1239
WERAM-Anp-0079 ENSAPLP00000009519.1 Anas platyrhynchos 81 0.0 1233
WERAM-Myl-0074 ENSMLUP00000006040.2 Myotis lucifugus 86 0.0 1231
WERAM-Dio-0020 ENSDORP00000002354.1 Dipodomys ordii 79 0.0 1192
WERAM-Prc-0004 ENSPCAP00000000473.1 Procavia capensis 77 0.0 1107
WERAM-Meg-0105 ENSMGAP00000010668.1 Meleagris gallopavo 76 0.0 1083
WERAM-Leo-0108 ENSLOCP00000014009.1 Lepisosteus oculatus 71 0.0 1031
WERAM-Tag-0040 ENSTGUP00000002713.1 Taeniopygia guttata 74 0.0 969
WERAM-Vip-0084 ENSVPAP00000007862.1 Vicugna pacos 82 0.0 805
WERAM-Dar-0170 ENSDARP00000100072.2 Danio rerio 56 0.0 790
WERAM-Mum-0019 ENSMUSP00000102770.2 Mus musculus 55 0.0 774
WERAM-Chs-0068 ENSCSAP00000002314.1 Chlorocebus sabaeus 55 0.0 772
WERAM-Ora-0108 ENSOANP00000020481.2 Ornithorhynchus anatinus 55 0.0 771
WERAM-Otg-0108 ENSOGAP00000009396.2 Otolemur garnettii 54 0.0 771
WERAM-Mim-0009 ENSMICP00000000769.1 Microcebus murinus 87 0.0 770
WERAM-Sah-0166 ENSSHAP00000017733.1 Sarcophilus harrisii 56 0.0 770
WERAM-Lac-0155 ENSLACP00000018356.1 Latimeria chalumnae 56 0.0 768
WERAM-Sus-0169 ENSSSCP00000025173.1 Sus scrofa 56 0.0 768
WERAM-Dan-0156 ENSDNOP00000017844.1 Dasypus novemcinctus 55 0.0 766
WERAM-Fec-0140 ENSFCAP00000013207.3 Felis catus 56 0.0 765
WERAM-Xet-0035 ENSXETP00000010592.2 Xenopus tropicalis 55 0.0 745
WERAM-Anc-0099 ENSACAP00000009498.3 Anolis carolinensis 55 0.0 735
WERAM-Mae-0145 ENSMEUP00000015025.1 Macropus eugenii 52 0.0 697
WERAM-Orn-0049 ENSONIP00000005635.1 Oreochromis niloticus 51 0.0 694
WERAM-Xim-0022 ENSXMAP00000002092.1 Xiphophorus maculatus 50 0.0 688
WERAM-Pof-0029 ENSPFOP00000001978.1 Poecilia formosa 50 0.0 673
WERAM-Pem-0041 ENSPMAP00000005402.1 Petromyzon marinus 50 0.0 667
WERAM-Ptv-0048 ENSPVAP00000005230.1 Pteropus vampyrus 91 0.0 657
WERAM-Tub-0129 ENSTBEP00000014362.1 Tupaia belangeri 68 0.0 654
WERAM-Asm-0202 ENSAMXP00000018862.1 Astyanax mexicanus 51 0.0 649
WERAM-Tar-0171 ENSTRUP00000035900.1 Takifugu rubripes 51 4e-180 629
WERAM-Chh-0086 ENSCHOP00000009630.1 Choloepus hoffmanni 86 3e-176 616
WERAM-Gaa-0148 ENSGACP00000019223.1 Gasterosteus aculeatus 50 2e-165 580
WERAM-Ten-0172 ENSTNIP00000017010.1 Tetraodon nigroviridis 76 5e-145 513
WERAM-Orla-0199 ENSORLP00000022663.1 Oryzias latipes 68 4e-139 493
WERAM-Ect-0082 ENSETEP00000009275.1 Echinops telfairi 78 1e-138 491
WERAM-Gam-0063 ENSGMOP00000006368.1 Gadus morhua 61 2e-122 437
WERAM-Drm-0080 FBpp0290513 Drosophila melanogaster 62 3e-117 420
WERAM-Cii-0046 ENSCINP00000016829.3 Ciona intestinalis 52 2e-100 364
WERAM-Cae-0008 C10E2.3a Caenorhabditis elegans 52 3e-94 344
WERAM-Brr-0181 Bra035942.1-P Brassica rapa 45 3e-66 251
WERAM-Bro-0168 Bo9g014470.1 Brassica oleracea 45 6e-66 250
WERAM-Sol-0055 Solyc03g115150.2.1 Solanum lycopersicum 43 6e-64 243
WERAM-Lep-0079 LPERR07G18450.1 Leersia perrieri 43 6e-63 240
WERAM-Sem-0022 EFJ08599 Selaginella moellendorffii 42 7e-63 239
WERAM-Thc-0031 EOY22062 Theobroma cacao 43 5e-62 237
WERAM-Orgl-0076 OGLUM07G21150.1 Oryza glumaepatula 44 5e-62 237
WERAM-Ori-0088 BGIOSGA026083-PA Oryza indica 44 6e-62 236
WERAM-Arl-0149 scaffold_802745.1 Arabidopsis lyrata 44 7e-62 236
WERAM-Ors-0072 OS07T0602200-01 Oryza sativa 44 7e-62 236
WERAM-Orr-0082 ORUFI07G22240.1 Oryza rufipogon 44 7e-62 236
WERAM-Orni-0078 ONIVA07G19970.1 Oryza nivara 44 8e-62 236
Created Date 25-Jun-2016