WERAM Information

Tag Content
WERAM ID WERAM-Hos-0039
Ensembl Protein ID ENSP00000380136.3
Uniprot Accession Q92794; KAT6A_HUMAN; Q76L81
Genbank Protein ID NP_006757.2
Protein Name Histone acetyltransferase KAT6A
Genbank Nucleotide ID NM_006766.4
Gene Name KAT6A;MOZ;MYST3;RUNXBP2;ZNF220
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000083168.9 ENST00000396930.3 ENSP00000380136.3
ENSG00000083168.9 ENST00000265713.6 ENSP00000265713.2
ENSG00000083168.9 ENST00000406337.5 ENSP00000385888.1
ENSG00000083168.9 ENST00000418721.5 ENSP00000399638.1
ENSG00000083168.9 ENST00000485568.5 ENSP00000430606.1
Details
Type Family Domain Substrates AA References (PMIDs)
Ac_Reader Tandem-PHD PHD1;PHD2 H3K9; H3K14 K 26266342; 23063713
HAT MYST MYST-type HAT H3K9; H3K14; H4K5; H4K8; H4K12; H4K16 K 11742995; 25728777
Status Reviewed
Classification
Type Family E-value Score Start End
HAT MYST 4.30e-129 431.9 505 778
Me_Reader PHD 1.20e-12 50 207 311
Ac_Reader Tandem-PHD 2.70e-41 127 206 265
Organism Homo sapiens
NCBI Taxa ID 9606
Functional Description
(View)		 Histone acetyltransferase that acetylates lysine residues in histone H3 and histone H4 (in vitro). Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. May act as a transcriptional coactivator for RUNX1 and RUNX2. Acetylates p53/TP53 at 'Lys-120' and 'Lys-382' and controls its transcriptional activity via association with PML.
Domain Profile
  HAT MYST
           MYST.txt   2 kvkniekielgkyeiktwysspfpeelkklkklyicefclkytkskeslkrhlkkCklrkpPgneiyrkdklsvfevdGkkqklycqnlCll 93 
                        +v+  ++ie+gkyei+twyssp+p+e+++l+kly+cefclky+ks+++l++h+kkC +++pP+neiyrk+++svfevdG+ +++ycqnlCll
  ENSP00000380136.3 505 QVRCPSVIEFGKYEIHTWYSSPYPQEYSRLPKLYLCEFCLKYMKSRTILQQHMKKCGWFHPPANEIYRKNNISVFEVDGNVSTIYCQNLCLL 596
                        578899************************************************************************************** PP
           MYST.txt  94 aklfldhktlyydvepflFYvltetdekgahlvGyFskekesaekynlaCilvlPpyqrkGyGklLiefsYelsrkegkigsPekPLsdlgl 185
                        aklfldhktlyydvepflFYvlt++d kg+hlvGyFskek++++kyn++Ci++lP+yqrkGyG++Li+fsY+ls++eg++gsPekPLsdlg+
  ENSP00000380136.3 597 AKLFLDHKTLYYDVEPFLFYVLTQNDVKGCHLVGYFSKEKHCQQKYNVSCIMILPQYQRKGYGRFLIDFSYLLSKREGQAGSPEKPLSDLGR 688
                        ******************************************************************************************** PP
           MYST.txt 186 lsYrsyWkevllellkekeekkkitikelskatgiaveDivstleslnlikekkgqyillksekiveellklakskkkklkvdeeklkwkp 276
                        lsY++yWk+v+le+l  ++++k+i+ik+lsk tgi+++Di stl++l++++ +++q++++++ek++++++ + + + + ++vd+e+l+w+p
  ENSP00000380136.3 689 LSYMAYWKSVILECL-YHQNDKQISIKKLSKLTGICPQDITSTLHHLRMLDFRSDQFVIIRREKLIQDHMAKLQLNLRPVDVDPECLRWTP 778
                        ***************.99***********************************************************************97 PP
  Me_Reader PHD
            PHD.txt   2 tiClvC.gkddegeke....mvqCdeCddwfHlkCvklp..lsslp.egkswyCpsCke 52 
                        +iC +C g++++++++    ++ C  C +  H +C+k++  l ++  +   w C +Ck+
  ENSP00000380136.3 207 PICSFClGTKEQNREKkpeeLISCADCGNSGHPSCLKFSpeL-TVRvKALRWQCIECKT 264
                        69****65444443334778*****************99432.22224467******96 PP
            PHD.txt   3 iClvCgkddegekemvqCdeCddwfHlkCvklplsslpegkswyCpsCk 51 
                        +C  C++++++++ m+ Cd+Cd+ fH++C ++pl+++p+g  w+C+ C+
  ENSP00000380136.3 264 TCSSCRDQGKNADNMLFCDSCDRGFHMECCDPPLTRMPKG-MWICQICR 311
                        7****999999999**************************.*******8 PP
  Ac_Reader Tandem-PHD
           PHD1.txt   1 inicdfclGtkesnkkkkPeelvscadcGrsGhPsclkftlelteavkalkWqciecksc 60 
                        i+ic+fclGtke+n++kkPeel+scadcG+sGhPsclkf++elt++vkal+Wqcieck+c
  ENSP00000380136.3 206 IPICSFCLGTKEQNREKKPEELISCADCGNSGHPSCLKFSPELTVRVKALRWQCIECKTC 265
                        69********************************************************** PP
           PHD1.txt  17 kkPeelvscadcGrsGhPsclkftleltea 46 
                        k  ++++ c  c r  h  c    + lt  
  ENSP00000380136.3 273 KNADNMLFCDSCDRGFHMECCD--PPLTRM 300
                        56788999*9***999999964..455555 PP
           PHD1.txt   3 icdfcl 8  
                        +c+fcl
  ENSP00000380136.3 539 LCEFCL 544
                        59***9 PP
Protein Sequence
(Fasta)		MVKLANPLYT EWILEAIKKV KKQKQRPSEE RICNAVSSSH GLDRKTVLEQ LELSVKDGTI 60
LKVSNKGLNS YKDPDNPGRI ALPKPRNHGK LDNKQNVDWN KLIKRAVEGL AESGGSTLKS 120
IERFLKGQKD VSALFGGSAA SGFHQQLRLA IKRAIGHGRL LKDGPLYRLN TKATNVDGKE 180
SCESLSCLPP VSLLPHEKDK PVAEPIPICS FCLGTKEQNR EKKPEELISC ADCGNSGHPS 240
CLKFSPELTV RVKALRWQCI ECKTCSSCRD QGKNADNMLF CDSCDRGFHM ECCDPPLTRM 300
PKGMWICQIC RPRKKGRKLL QKKAAQIKRR YTNPIGRPKN RLKKQNTVSK GPFSKVRTGP 360
GRGRKRKITL SSQSASSSSE EGYLERIDGL DFCRDSNVSL KFNKKTKGLI DGLTKFFTPS 420
PDGRKARGEV VDYSEQYRIR KRGNRKSSTS DWPTDNQDGW DGKQENEERL FGSQEIMTEK 480
DMELFRDIQE QALQKVGVTG PPDPQVRCPS VIEFGKYEIH TWYSSPYPQE YSRLPKLYLC 540
EFCLKYMKSR TILQQHMKKC GWFHPPANEI YRKNNISVFE VDGNVSTIYC QNLCLLAKLF 600
LDHKTLYYDV EPFLFYVLTQ NDVKGCHLVG YFSKEKHCQQ KYNVSCIMIL PQYQRKGYGR 660
FLIDFSYLLS KREGQAGSPE KPLSDLGRLS YMAYWKSVIL ECLYHQNDKQ ISIKKLSKLT 720
GICPQDITST LHHLRMLDFR SDQFVIIRRE KLIQDHMAKL QLNLRPVDVD PECLRWTPVI 780
VSNSVVSEEE EEEAEEGENE EPQCQERELE ISVGKSVSHE NKEQDSYSVE SEKKPEVMAP 840
VSSTRLSKQV LPHDSLPANS QPSRRGRWGR KNRKTQERFG DKDSKLLLEE TSSAPQEQYG 900
ECGEKSEATQ EQYTESEEQL VASEEQPSQD GKPDLPKRRL SEGVEPWRGQ LKKSPEALKC 960
RLTEGSERLP RRYSEGDRAV LRGFSESSEE EEEPESPRSS SPPILTKPTL KRKKPFLHRR 1020
RRVRKRKHHN SSVVTETISE TTEVLDEPFE DSDSERPMPR LEPTFEIDEE EEEEDENELF 1080
PREYFRRLSS QDVLRCQSSS KRKSKDEEED EESDDADDTP ILKPVSLLRK RDVKNSPLEP 1140
DTSTPLKKKK GWPKGKSRKP IHWKKRPGRK PGFKLSREIM PVSTQACVIE PIVSIPKAGR 1200
KPKIQESEET VEPKEDMPLP EERKEEEEMQ AEAEEAEEGE EEDAASSEVP AASPADSSNS 1260
PETETKEPEV EEEEEKPRVS EEQRQSEEEQ QELEEPEPEE EEDAAAETAQ NDDHDADDED 1320
DGHLESTKKK ELEEQPTRED VKEEPGVQES FLDANMQKSR EKIKDKEETE LDSEEEQPSH 1380
DTSVVSEQMA GSEDDHEEDS HTKEELIELK EEEEIPHSEL DLETVQAVQS LTQEESSEHE 1440
GAYQDCEETL AACQTLQSYT QADEDPQMSM VEDCHASEHN SPISSVQSHP SQSVRSVSSP 1500
NVPALESGYT QISPEQGSLS APSMQNMETS PMMDVPSVSD HSQQVVDSGF SDLGSIESTT 1560
ENYENPSSYD STMGGSICGN SSSQSSCSYG GLSSSSSLTQ SSCVVTQQMA SMGSSCSMMQ 1620
QSSVQPAANC SIKSPQSCVV ERPPSNQQQQ PPPPPPQQPQ PPPPQPQPAP QPPPPQQQPQ 1680
QQPQPQPQQP PPPPPPQQQP PLSQCSMNNS FTPAPMIMEI PESGSTGNIS IYERIPGDFG 1740
AGSYSQPSAT FSLAKLQQLT NTIMDPHAMP YSHSPAVTSY ATSVSLSNTG LAQLAPSHPL 1800
AGTPQAQATM TPPPNLASTT MNLTSPLLQC NMSATNIGIP HTQRLQGQMP VKGHISIRSK 1860
SAPLPSAAAH QQQLYGRSPS AVAMQAGPRA LAVQRGMNMG VNLMPTPAYN VNSMNMNTLN 1920
AMNSYRMTQP MMNSSYHSNP AYMNQTAQYP MQMQMGMMGS QAYTQQPMQP NPHGNMMYTG 1980
PSHHSYMNAA GVPKQSLNGP YMRR 2004
Nucleotide Sequence
(Fasta)		ACTGTCTCCA AGATGGCGGC CGTGTCAGTT TGGGGCATCT CCGCGGTCCG GCCCGGGGCC 60
CCGGGATCTC GGCTGTCCTT CCTCCCGGAT TCTTTCTACT AATCCAGATA CTTGTTGAAG 120
TGCTGACTAG TTTCTTGGGG AAAGATGTCA AGGAAGAGTT GAAATTCCTA GACTGGTGAG 180
CAGAGATTGC GGAGTACAGA ATAGCCATCA CCCACTCTGG CATAAGATGC ACATTTTTCT 240
GCTCTGGAGC CGGGAATGAA ATATTCTTGA GTTCTTACAA CTTTATGACG AGACCCATGT 300
GTGGTGCTAT TGAGAAATTC ATTGGGAAGT TGGAAGACAT TTCAATCAAC AGGTTGTTTT 360
GGTTTCTATA GTACAATTGG GGTGGCATTC TGTTTTGTGA AAGGAGGAAG GACTTAGGCC 420
AGAAAACTCA TATGCTATGG TTAACTGGTT CCCAGCCTCC GAGAATCTTG TTTTCCATGG 480
TGTAAAACTT ACTCAGCATC AGGATAAGGG ATAACGACTC TATGGATATA CAGAATCCTT 540
CACCATGGTA AAACTCGCAA ACCCGCTTTA TACTGAGTGG ATTTTGGAGG CCATCAAAAA 600
AGTGAAAAAG CAGAAACAGC GTCCTTCAGA AGAAAGGATA TGCAATGCTG TGTCTTCATC 660
CCATGGCTTG GATCGTAAAA CTGTTTTAGA ACAATTGGAG TTGAGTGTTA AAGATGGAAC 720
AATTTTAAAA GTCTCAAATA AAGGACTCAA TTCCTATAAA GATCCTGATA ATCCTGGGCG 780
AATAGCACTT CCTAAGCCTC GGAACCATGG AAAATTGGAT AATAAACAAA ATGTGGATTG 840
GAATAAACTG ATAAAGCGGG CAGTTGAGGG CTTGGCAGAG TCTGGTGGCT CAACTTTGAA 900
AAGCATTGAA CGTTTTTTGA AAGGTCAGAA GGATGTGTCT GCATTATTCG GAGGCAGTGC 960
TGCCTCTGGC TTTCACCAGC AGTTACGATT GGCTATCAAA CGTGCCATTG GCCACGGCAG 1020
ACTCCTTAAA GATGGACCTC TTTATCGGCT CAACACTAAA GCAACCAACG TGGATGGGAA 1080
AGAGAGTTGT GAGTCTCTTT CCTGTTTACC TCCAGTGTCC CTTCTTCCAC ATGAAAAGGA 1140
TAAGCCGGTT GCTGAACCAA TCCCCATCTG TAGTTTCTGT CTTGGTACAA AAGAACAAAA 1200
CCGAGAAAAG AAGCCAGAGG AACTCATCTC CTGTGCCGAC TGTGGCAACA GTGGCCATCC 1260
ATCCTGTTTA AAGTTTTCCC CTGAACTAAC GGTTCGAGTG AAGGCCTTAC GGTGGCAGTG 1320
CATCGAGTGT AAAACATGCA GCTCCTGTCG AGATCAAGGC AAAAATGCGG ATAACATGCT 1380
CTTTTGTGAT TCATGTGACC GAGGTTTTCA CATGGAGTGT TGTGATCCGC CACTCACCCG 1440
TATGCCAAAA GGCATGTGGA TATGTCAAAT ATGTCGACCT AGGAAAAAAG GACGAAAACT 1500
TCTACAAAAG AAGGCAGCAC AGATAAAACG GCGCTATACT AATCCAATAG GACGTCCAAA 1560
AAACAGGTTA AAGAAACAAA ACACGGTATC AAAAGGTCCC TTCAGCAAAG TTCGAACTGG 1620
CCCTGGAAGG GGTAGGAAAC GAAAAATCAC TCTTTCCAGC CAATCAGCAT CATCATCATC 1680
AGAAGAAGGA TATTTAGAGC GGATAGATGG CTTGGACTTC TGCAGAGATA GCAATGTCTC 1740
CTTGAAGTTC AACAAGAAAA CCAAAGGGCT CATTGATGGC CTTACCAAAT TTTTTACCCC 1800
TTCCCCTGAT GGGCGGAAAG CTCGGGGGGA AGTGGTGGAC TACTCTGAGC AATATCGAAT 1860
CAGAAAGAGG GGCAACAGGA AATCAAGCAC TTCAGATTGG CCCACAGACA ATCAGGATGG 1920
CTGGGATGGC AAACAAGAAA ATGAGGAGCG ACTTTTTGGG AGCCAGGAAA TCATGACTGA 1980
GAAAGATATG GAATTATTTC GTGATATCCA AGAACAAGCA CTGCAGAAAG TTGGAGTGAC 2040
TGGTCCCCCT GATCCACAAG TCCGCTGTCC CTCTGTCATT GAGTTTGGGA AGTATGAAAT 2100
TCACACCTGG TACTCCTCCC CATATCCTCA AGAATACTCA AGGCTGCCCA AATTGTATCT 2160
TTGTGAATTT TGTCTAAAAT ATATGAAAAG TAGAACTATT CTGCAGCAGC ACATGAAGAA 2220
ATGTGGTTGG TTCCATCCTC CTGCCAATGA GATTTACAGA AAGAATAATA TTTCTGTCTT 2280
TGAGGTTGAT GGGAATGTGA GTACCATTTA TTGTCAAAAC CTGTGTCTTT TGGCAAAGTT 2340
GTTTCTTGAC CACAAAACCC TCTATTACGA TGTGGAGCCA TTTCTTTTTT ATGTACTAAC 2400
ACAGAATGAT GTCAAGGGCT GCCACCTTGT TGGCTACTTT TCTAAGGAAA AGCACTGCCA 2460
ACAGAAGTAC AATGTTTCCT GTATAATGAT TCTTCCTCAA TACCAGCGTA AGGGCTATGG 2520
CAGGTTTCTC ATCGATTTCA GTTATTTGTT ATCAAAGCGT GAAGGCCAAG CAGGGTCTCC 2580
AGAGAAACCG TTATCTGATC TGGGTCGTCT TTCCTACATG GCATATTGGA AAAGTGTAAT 2640
ATTGGAGTGC CTTTATCACC AAAATGACAA GCAGATCAGC ATTAAGAAGT TAAGCAAGTT 2700
GACTGGAATC TGCCCTCAAG ACATCACTTC CACACTCCAC CACCTACGAA TGCTGGACTT 2760
CCGTAGTGAC CAATTTGTGA TTATCCGCCG GGAAAAACTT ATCCAGGATC ACATGGCAAA 2820
GCTTCAGCTG AATTTGCGAC CTGTAGATGT AGATCCAGAA TGTTTGCGCT GGACTCCAGT 2880
CATAGTGTCC AACTCTGTGG TCTCAGAGGA GGAAGAAGAG GAGGCTGAGG AAGGAGAAAA 2940
CGAAGAGCCA CAGTGCCAGG AAAGAGAATT AGAGATCAGT GTGGGAAAGT CTGTGTCTCA 3000
TGAGAACAAA GAACAAGATT CTTATTCAGT AGAAAGTGAA AAGAAACCAG AAGTTATGGC 3060
TCCAGTCAGT TCTACACGTT TGAGCAAACA AGTCCTTCCT CATGATAGTC TTCCTGCAAA 3120
TAGCCAGCCA TCTCGGAGGG GCCGCTGGGG GAGGAAGAAC AGAAAAACCC AGGAACGTTT 3180
TGGTGATAAA GATTCTAAAC TGCTCTTGGA AGAGACGTCT TCAGCTCCTC AGGAACAATA 3240
TGGAGAATGT GGGGAGAAAT CAGAAGCCAC CCAGGAACAA TACACTGAAA GTGAAGAACA 3300
GCTGGTGGCT TCTGAGGAGC AGCCAAGCCA GGACGGGAAA CCTGACCTTC CCAAGAGAAG 3360
ACTCAGTGAG GGGGTTGAGC CCTGGCGAGG ACAGCTCAAG AAAAGCCCTG AGGCTCTGAA 3420
GTGCAGATTA ACAGAAGGAA GTGAGAGGCT GCCCCGTCGC TACAGTGAGG GTGACAGGGC 3480
TGTCCTCAGG GGCTTCAGTG AGAGCAGCGA GGAGGAGGAG GAGCCGGAAA GCCCTCGGTC 3540
AAGCTCGCCA CCAATTCTCA CAAAGCCCAC GCTGAAGCGA AAGAAACCAT TTCTCCACCG 3600
AAGGAGGAGA GTCCGAAAGC GCAAACACCA CAATAGCAGT GTAGTCACAG AAACTATTTC 3660
TGAGACCACT GAAGTGTTAG ATGAACCTTT TGAAGATTCT GACTCCGAGA GGCCAATGCC 3720
AAGATTAGAA CCCACGTTTG AGATCGATGA AGAAGAGGAG GAAGAGGATG AAAATGAACT 3780
TTTCCCTAGA GAATACTTCC GTCGTTTGTC TTCGCAGGAT GTACTCAGGT GTCAGTCCTC 3840
TTCTAAGAGG AAGTCTAAAG ATGAAGAAGA AGATGAAGAG TCAGATGATG CTGATGACAC 3900
TCCTATCTTA AAGCCAGTAT CTCTTTTGCG AAAACGTGAT GTGAAGAATT CTCCTCTTGA 3960
GCCAGATACA TCCACACCTT TGAAAAAGAA AAAGGGATGG CCCAAAGGCA AGAGCCGCAA 4020
ACCAATCCAC TGGAAGAAAA GACCTGGTCG AAAACCAGGA TTTAAGTTGA GTCGGGAAAT 4080
CATGCCAGTT TCTACTCAAG CATGCGTCAT TGAGCCCATC GTTTCCATTC CTAAAGCTGG 4140
ACGTAAACCC AAGATCCAGG AGAGTGAAGA AACTGTTGAG CCAAAAGAAG ACATGCCCCT 4200
ACCCGAGGAG AGGAAGGAGG AGGAGGAGAT GCAAGCAGAG GCAGAAGAGG CTGAAGAGGG 4260
TGAGGAAGAG GATGCAGCCA GCAGTGAAGT CCCAGCAGCC TCTCCAGCAG ACAGCAGCAA 4320
TAGTCCTGAG ACCGAAACCA AGGAGCCTGA GGTGGAGGAG GAAGAAGAGA AGCCCCGTGT 4380
CTCAGAGGAG CAGAGGCAGT CAGAGGAGGA GCAGCAGGAA TTAGAGGAGC CAGAGCCAGA 4440
GGAGGAGGAA GATGCAGCTG CAGAGACTGC CCAGAATGAC GACCACGACG CTGATGATGA 4500
GGATGATGGC CACCTGGAGT CCACAAAGAA AAAGGAGCTA GAGGAACAGC CCACGAGGGA 4560
AGATGTCAAG GAGGAGCCTG GTGTTCAAGA GTCTTTTTTA GATGCTAATA TGCAGAAGAG 4620
TAGGGAAAAG ATAAAGGATA AAGAGGAAAC CGAGCTGGAT TCCGAAGAGG AGCAGCCTTC 4680
CCATGACACG TCCGTGGTGT CAGAGCAGAT GGCTGGGTCT GAGGACGACC ACGAAGAAGA 4740
CTCCCACACT AAGGAAGAGT TAATCGAATT AAAAGAGGAG GAAGAGATTC CTCATAGTGA 4800
GCTGGATCTG GAAACTGTAC AGGCAGTGCA GTCTTTGACT CAAGAAGAAA GCAGTGAGCA 4860
TGAGGGCGCC TACCAGGACT GTGAGGAAAC TCTTGCGGCG TGTCAGACCC TGCAGAGTTA 4920
CACCCAGGCT GACGAGGACC CTCAGATGTC CATGGTTGAA GACTGTCATG CGTCAGAACA 4980
TAATAGCCCT ATCTCCTCCG TTCAGTCTCA CCCCAGCCAG TCAGTCCGTT CGGTCAGCAG 5040
TCCCAACGTG CCTGCCCTTG AGAGTGGCTA CACCCAGATC AGCCCAGAAC AAGGATCCCT 5100
GTCCGCACCC TCTATGCAGA ACATGGAGAC CAGCCCCATG ATGGATGTGC CTTCCGTATC 5160
AGACCACTCT CAGCAGGTGG TGGACAGCGG CTTCAGTGAC CTGGGCAGCA TTGAGAGCAC 5220
CACTGAAAAC TATGAGAACC CAAGCAGTTA CGACTCCACG ATGGGCGGCA GCATCTGTGG 5280
GAACAGCTCT TCCCAGAGCA GCTGCTCCTA CGGTGGGCTG TCGTCCTCCA GCAGCCTCAC 5340
CCAGAGCAGC TGTGTGGTCA CTCAGCAGAT GGCCAGCATG GGCAGCAGCT GCAGCATGAT 5400
GCAGCAGAGC AGCGTCCAGC CTGCTGCCAA CTGCAGCATC AAGTCACCTC AGAGCTGCGT 5460
GGTGGAGAGG CCTCCCAGTA ACCAGCAGCA GCAGCCGCCA CCACCGCCTC CACAGCAGCC 5520
ACAGCCGCCG CCGCCACAAC CACAACCAGC ACCACAGCCT CCACCACCCC AGCAGCAGCC 5580
GCAACAGCAG CCGCAGCCTC AGCCCCAGCA GCCTCCACCC CCACCCCCTC CCCAGCAGCA 5640
GCCCCCGCTG TCACAGTGTA GTATGAATAA CAGTTTCACC CCAGCTCCTA TGATCATGGA 5700
GATACCAGAA TCTGGAAGCA CTGGGAACAT AAGTATCTAT GAGAGGATTC CAGGGGATTT 5760
TGGTGCCGGC AGCTACTCTC AACCATCAGC CACCTTCAGC CTAGCCAAGC TGCAGCAGCT 5820
GACCAACACC ATTATGGACC CTCATGCCAT GCCTTATAGC CATTCTCCTG CTGTGACTTC 5880
CTATGCAACC AGTGTTTCTC TGTCCAATAC AGGACTGGCT CAGCTGGCTC CATCTCATCC 5940
CTTAGCTGGG ACTCCTCAAG CACAAGCCAC CATGACGCCA CCCCCAAACT TGGCATCCAC 6000
TACCATGAAC CTCACATCTC CTCTGCTTCA GTGCAACATG TCTGCCACCA ACATTGGCAT 6060
TCCTCACACG CAGAGATTGC AAGGGCAAAT GCCAGTGAAG GGGCACATTT CCATCCGCTC 6120
CAAGTCTGCG CCACTGCCCT CTGCGGCTGC TCACCAGCAG CAGCTGTATG GCCGTAGCCC 6180
ATCGGCAGTT GCCATGCAGG CTGGCCCTCG CGCACTGGCT GTTCAGCGTG GCATGAACAT 6240
GGGGGTTAAT CTGATGCCTA CTCCCGCCTA TAATGTCAAT TCCATGAATA TGAACACCTT 6300
GAATGCCATG AACAGCTATC GAATGACACA GCCCATGATG AACAGCAGTT ACCATAGTAA 6360
CCCTGCCTAC ATGAACCAGA CAGCACAGTA TCCTATGCAG ATGCAGATGG GAATGATGGG 6420
GAGCCAGGCC TATACCCAGC AGCCTATGCA GCCTAACCCT CATGGGAACA TGATGTACAC 6480
AGGCCCCTCC CATCACAGCT ACATGAACGC TGCTGGCGTG CCCAAGCAGT CACTCAACGG 6540
ACCTTACATG AGAAGATGAG CAAGATGAAC TTGCAATCAA AAACTTAAAT ATATATAAAT 6600
AAAGGAACCT TTTATACTGA CAAACCAGAG AAAAATGGAC CTTTTTCCAG TTAAAATATT 6660
GCTGTAGATT TAGAGGAATT TTTCTTTGGT TTATTTTATT TTTTAGAAAA CCTGATCTTC 6720
TCTTTTTTTG GGTTCATTTT GTTCTGGGTT TTGGTTTTCT TCACAATCTT GAACATTTTA 6780
CAGTAGAACT CATCTAAAAA TGGATTTGGG GATGGGGAAA CATGCACAAA ATCTTTTCAT 6840
AATTAAAAAG AGCCTTACTT TCTTTACATA CCACATGGAC AGAATTTGTG TAAAAGTGAA 6900
TTATCTTTAT TTTAAAATGT ATGTTTCCCC TCACTGTTTG CAGCTCCCAA TGTTGTCATT 6960
TTTAAATGTT ATATACATCT CAAGGGTTAA CCAGACCCTT TCCTCCAAAC CCAACCTTTC 7020
ATTTCCTACT TCATTCCAGC AGGAGGCACT TAGGGGAGAC TCGGATGGGG ACATGGAGAA 7080
CAACCCAAGC TCCTTAAACT TATTATTATT GTTAATATTA TTATTATTAT TATTAATAAA 7140
GTGAGGCAGG AAAATGCTTC TCCTTTTAAA ATCCCCTCCA CTCCTCACAC ACACACACCT 7200
CTTGAAACCC TTCCCCAAGA ATGTTTCTTT ATAGACGGAC TTCATTGAAA TCTTTGTTGT 7260
TCTTGAATCA AGTGTAATAT AATTTTTTTC TTCTTTTTTA AAATATTCCC ACTCAGCACT 7320
CAGAGACACA AAAATACTGT AAGTCTCAAT TAACAGCAGA ATCTCAGAGA AAAGCTGTTT 7380
GCAATCCAAA TCCAGCCTTT GGAGGAATAG AGATGGTCAA TTAACAATCA AAAAGAGGAG 7440
ATTAACCTCT TGTTTTTTTA CCACCTGGTG AATCAGCCAT AACGCACACA CACGCCACCC 7500
AGCCTCTTGT TTCTAGTATG TACTTTGAAA TGCTAACTGA GGGTCTTGAT GCTTGAGCCT 7560
TTGACTGATA AAACTCAAAT AGCAGTCCCC AGTGATTTGC CTCTTAGGTT CTTTCTTAAA 7620
TTGTTGGTGG ATGACTGTAC ATTTTAGTGA TTTGAAAAAT AACTGACAAA CCATTGAAAC 7680
AGTTTATTTT ATGTTGGAAG AGATGGCGCA GATGTGTGTC AGAAGGGAGA TCACGGTGTG 7740
AGTTTCGTAG CTATTTAAGT GATACATACC TCTAGTTTTT GTATGTCTTT TGAGATCCTG 7800
AGTTCATCCC CTGTGAATCA GAGTGCACAA GCACCTCTCC TGTGAGTGGC TAATGAGAAG 7860
AGGGACAGAC CGACCACCAG CACAGTAGGG CAGATCTGGA CAGCAGAATG TTATAACGCA 7920
AGTTCATGTG TTGCTCCCAA CTCCATTCTC TTTTCTCTCG TGCAACCAGT TTGCCCATTC 7980
TCTTCCTATT ACTTGCTCCA GGGATAGGTA AAAAAAAAAA AAAAAAAAAA AAAAATATAT 8040
ATATATATAT ATACACACAC ACACACACAC ACACACACAC ATATATATAT ATATATATTC 8100
CATCATTAGA AGATGGAAAC TATTATACCA CTTGGTATGT GCAGTCAAAT ATCCAAAAGG 8160
GGGAAGTACT GCTTAGAGAA ATATCTGTAA GCATTAAATT CTCTCCTTTA TTTGTACATT 8220
TTATATAGAT AAATTTTTAA AGTACTAATT AGGCATTAAC TTTTTTCAAA TGCACAGGTT 8280
TGTTGGTTTT TTTAATACAC TTTAATTGAC TTTCTCAAGC GTGCTAGGTA GAAACGCAGA 8340
ATTCCACATC TTCCCGCTCT CAGCTCTGAG CATGTGCAAG GCTGTGTAGG ACCCAGTTTC 8400
TCTGTATATA CTATTCCAGT TCCCAGTCAT CTATGTAGAA AGTGCACTGT GCTGCCATCG 8460
CCCTACATCT TCAGCTGTGT CATTGCTTCC TGGTTGGGGT GGGGACGGGG TGGGTCGGGA 8520
GGGAGGTATA TTGGGAGGAG GGTGGGTCAA GGCAGAAGGA GAAGCTGTTG AAATGAGGGC 8580
CGTGAAATCA GTTTCTGTTG GTTTGCGGTT GTGTTTGGTT TTGTTTGTTT CTTTATAAAA 8640
AATTCAATCG GGCAGCTCCC TTTTCCACAA GCCTCTTTGT GACTGTAGAA CTATTGTAGA 8700
AAAAAAAAGT TCTTTTCTAT ATTATAAAAG AAATTATCCA ACACAGTAAT ATTGGTACCT 8760
GTCATTTTTT CACTTCTGTT TAAAAAAAAT GTATTTTTAG CAAGATAACT TGGGTAATCT 8820
TCTAAAAAAG AAATTTAAAA ACTCACTGTT AGTGACTTTG ATGCCTTTTA AAATAAGAGC 8880
TTTTTCATTT CATTCCATCT TTAAAATTTT TTATCTTTGT TGTAGAATAT TAAAAACTAT 8940
TTTAAGAAAG ATAAATTCTC TTTAAAGAGA TCTCTAGCGT GTGTGAATAG AGCTCCAGAT 9000
GCCTCTAAAA GCCGCATGTA CAAAGGAAGC CACGTCTATC CTGTCTGTTT ATATTTGCTT 9060
TTCCTGTTTT GTAACCTCTT TGTACTTTGT TCATGGTGAC TTGTAAGCTA AGGGGAAGGG 9120
GTGCCTAGAT GCCTTTGTAT CTCTCCATGT CACGCGCTCC TGGGCCAGCC GGCCTCCCTT 9180
CCTCTCCTTG TATGTAATAC CTTTTTTTCC CCTTTCTAGC AAGTACTTTC AAAAGAACTC 9240
TGTACATTTT AACATAAAAA ATAAATTATG TTGAGCCATT TTGGA 9286
Sequence Source Ensembl
Keyword

KW-0002--3D-structure
KW-0007--Acetylation
KW-0010--Activator
KW-0012--Acyltransferase
KW-0156--Chromatin regulator
KW-0160--Chromosomal rearrangement
KW-0181--Complete proteome
KW-0991--Mental retardation
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-0621--Polymorphism
KW-0656--Proto-oncogene
KW-1185--Reference proteome
KW-0677--Repeat
KW-0678--Repressor
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger
--
Interpro

IPR016181--Acyl_CoA_acyltransferase
IPR002717--HAT_MYST-type
IPR005818--Histone_H1/H5_H15
IPR031280--KAT6A
IPR011991--WHTH_DNA-bd_dom
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS51504--H15
PS51726--MYST_HAT
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2
Pfam

PF01853--MOZ_SAS
PF00628--PHD
Gene Ontology

GO:0005794--C:Golgi apparatus
GO:0070776--C:MOZ/MORF histone acetyltransferase complex
GO:0005730--C:nucleolus
GO:0005654--C:nucleoplasm
GO:0000786--C:nucleosome
GO:0005634--C:nucleus
GO:0016605--C:PML body
GO:0016407--F:acetyltransferase activity
GO:0003677--F:DNA binding
GO:0004402--F:histone acetyltransferase activity
GO:0003713--F:transcription coactivator activity
GO:0008134--F:transcription factor binding
GO:0008270--F:zinc ion binding
GO:0090398--P:cellular senescence
GO:0006323--P:DNA packaging
GO:0016573--P:histone acetylation
GO:0043966--P:histone H3 acetylation
GO:0030099--P:myeloid cell differentiation
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0006334--P:nucleosome assembly
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0006473--P:protein acetylation
GO:1901796--P:regulation of signal transduction by p53 class mediator
GO:0006351--P:transcription, DNA-templated
Orthology
WERAM ID Ensembl Protein ID Species Identity E-value Score
WERAM-Pat-0172 ENSPTRP00000034594.5 Pan troglodytes 100 0.0 2172
WERAM-Poa-0174 ENSPPYP00000020800.2 Pongo abelii 99 0.0 2157
WERAM-Nol-0142 ENSNLEP00000015494.1 Nomascus leucogenys 99 0.0 2153
WERAM-Paa-0164 ENSPANP00000007027.1 Papio anubis 98 0.0 2138
WERAM-Gog-0052 ENSGGOP00000004590.2 Gorilla gorilla 98 0.0 2133
WERAM-Fec-0202 ENSFCAP00000017012.1 Felis catus 95 0.0 2078
WERAM-Caf-0067 ENSCAFP00000008454.4 Canis familiaris 95 0.0 2076
WERAM-Mup-0067 ENSMPUP00000005726.1 Mustela putorius furo 95 0.0 2074
WERAM-Aim-0066 ENSAMEP00000005789.1 Ailuropoda melanoleuca 95 0.0 2071
WERAM-Eqc-0057 ENSECAP00000007930.1 Equus caballus 94 0.0 2046
WERAM-Loa-0054 ENSLAFP00000004071.3 Loxodonta africana 92 0.0 2016
WERAM-Myl-0190 ENSMLUP00000015906.2 Myotis lucifugus 93 0.0 2009
WERAM-Bot-0050 ENSBTAP00000005242.5 Bos taurus 91 0.0 2004
WERAM-Ova-0021 ENSOARP00000003148.1 Ovis aries 89 0.0 1969
WERAM-Ptv-0164 ENSPVAP00000013957.1 Pteropus vampyrus 91 0.0 1953
WERAM-Mum-0121 ENSMUSP00000106324.1 Mus musculus 88 0.0 1942
WERAM-Sah-0187 ENSSHAP00000020344.1 Sarcophilus harrisii 89 0.0 1939
WERAM-Dio-0138 ENSDORP00000012841.1 Dipodomys ordii 89 0.0 1936
WERAM-Ran-0156 ENSRNOP00000037279.5 Rattus norvegicus 89 0.0 1920
WERAM-Ora-0008 ENSOANP00000001123.3 Ornithorhynchus anatinus 87 0.0 1905
WERAM-Ect-0123 ENSETEP00000014407.1 Echinops telfairi 93 0.0 1859
WERAM-Mim-0065 ENSMICP00000006346.1 Microcebus murinus 87 0.0 1828
WERAM-Orc-0007 ENSOCUP00000000635.2 Oryctolagus cuniculus 84 0.0 1798
WERAM-Tag-0076 ENSTGUP00000005580.1 Taeniopygia guttata 81 0.0 1796
WERAM-Anp-0054 ENSAPLP00000005897.1 Anas platyrhynchos 82 0.0 1794
WERAM-Prc-0131 ENSPCAP00000011682.1 Procavia capensis 90 0.0 1788
WERAM-Gaga-0039 ENSGALP00000005756.5 Gallus gallus 81 0.0 1785
WERAM-Fia-0083 ENSFALP00000006697.1 Ficedula albicollis 79 0.0 1783
WERAM-Meg-0033 ENSMGAP00000002954.2 Meleagris gallopavo 80 0.0 1776
WERAM-Mam-0094 ENSMMUP00000014290.2 Macaca mulatta 82 0.0 1733
WERAM-Mae-0035 ENSMEUP00000002978.1 Macropus eugenii 87 0.0 1706
WERAM-Anc-0133 ENSACAP00000012299.3 Anolis carolinensis 76 0.0 1678
WERAM-Ocp-0127 ENSOPRP00000013509.1 Ochotona princeps 80 0.0 1672
WERAM-Pes-0065 ENSPSIP00000008405.1 Pelodiscus sinensis 84 0.0 1671
WERAM-Chs-0182 ENSCSAP00000011159.1 Chlorocebus sabaeus 98 0.0 1610
WERAM-Cap-0131 ENSCPOP00000010518.2 Cavia porcellus 88 0.0 1596
WERAM-Tub-0015 ENSTBEP00000001544.1 Tupaia belangeri 98 0.0 1595
WERAM-Dan-0094 ENSDNOP00000009439.3 Dasypus novemcinctus 87 0.0 1538
WERAM-Vip-0046 ENSVPAP00000004212.1 Vicugna pacos 87 0.0 1457
WERAM-Tut-0027 ENSTTRP00000002105.1 Tursiops truncatus 87 0.0 1448
WERAM-Tas-0050 ENSTSYP00000004605.1 Tarsius syrichta 90 0.0 1335
WERAM-Leo-0160 ENSLOCP00000019211.1 Lepisosteus oculatus 77 0.0 1238
WERAM-Ten-0198 ENSTNIP00000019882.1 Tetraodon nigroviridis 75 0.0 1218
WERAM-Tar-0172 ENSTRUP00000036180.1 Takifugu rubripes 74 0.0 1209
WERAM-Dar-0048 ENSDARP00000014581.6 Danio rerio 73 0.0 1201
WERAM-Xim-0123 ENSXMAP00000010545.1 Xiphophorus maculatus 72 0.0 1184
WERAM-Orla-0165 ENSORLP00000019177.1 Oryzias latipes 69 0.0 1182
WERAM-Pof-0025 ENSPFOP00000001872.2 Poecilia formosa 71 0.0 1177
WERAM-Caj-0048 ENSCJAP00000007791.2 Callithrix jacchus 97 0.0 1174
WERAM-Gaa-0135 ENSGACP00000017301.1 Gasterosteus aculeatus 73 0.0 1163
WERAM-Gam-0083 ENSGMOP00000008636.1 Gadus morhua 73 0.0 1159
WERAM-Ere-0009 ENSEEUP00000000431.1 Erinaceus europaeus 85 0.0 1135
WERAM-Sus-0047 ENSSSCP00000007485.2 Sus scrofa 96 0.0 1133
WERAM-Ict-0179 ENSSTOP00000021229.1 Ictidomys tridecemlineatus 90 0.0 1125
WERAM-Otg-0021 ENSOGAP00000001038.2 Otolemur garnettii 95 0.0 872
WERAM-Chh-0072 ENSCHOP00000007845.1 Choloepus hoffmanni 83 0.0 857
WERAM-Soa-0009 ENSSARP00000000844.1 Sorex araneus 88 0.0 767
WERAM-Lac-0084 ENSLACP00000010819.1 Latimeria chalumnae 63 0.0 765
WERAM-Mod-0083 ENSMODP00000017666.2 Monodelphis domestica 69 0.0 751
WERAM-Orn-0193 ENSONIP00000019936.1 Oreochromis niloticus 70 3e-180 630
WERAM-Asm-0156 ENSAMXP00000015644.1 Astyanax mexicanus 68 8e-177 619
WERAM-Drm-0054 FBpp0072159 Drosophila melanogaster 56 1e-107 389
WERAM-Xet-0138 ENSXETP00000047416.3 Xenopus tropicalis 57 5e-103 374
WERAM-Pem-0064 ENSPMAP00000007030.1 Petromyzon marinus 55 2e-100 365
WERAM-Cii-0017 ENSCINP00000006517.3 Ciona intestinalis 52 7e-98 357
WERAM-Cis-0023 ENSCSAVP00000005035.1 Ciona savignyi 52 2e-95 349
WERAM-Zem-0080 GRMZM2G140288_P01 Zea mays 56 2e-87 322
WERAM-Art-0119 AT5G09740.1 Arabidopsis thaliana 56 8e-87 320
WERAM-Orl-0045 KN538920.1_FGP012 Oryza longistaminata 56 3e-86 318
WERAM-Bro-0183 Bo9g173870.1 Brassica oleracea 55 6e-86 317
WERAM-Arl-0101 fgenesh2_kg.6__ 927__ AT5G09740.1 Arabidopsis lyrata 55 6e-86 317
WERAM-Orbr-0089 OB07G28490.1 Oryza brachyantha 56 6e-86 317
WERAM-Brr-0045 Bra009399.1-P Brassica rapa 55 7e-86 317
WERAM-Sob-0038 Sb02g039960.1 Sorghum bicolor 56 7e-86 317
WERAM-Orp-0078 OPUNC07G21500.1 Oryza punctata 56 9e-86 317
WERAM-Ors-0074 OS07T0626600-01 Oryza sativa 56 1e-85 316
WERAM-Orr-0084 ORUFI07G24020.1 Oryza rufipogon 56 1e-85 316
WERAM-Orni-0080 ONIVA07G22490.1 Oryza nivara 56 1e-85 316
WERAM-Orm-0076 OMERI07G19290.1 Oryza meridionalis 56 1e-85 316
WERAM-Ori-0077 BGIOSGA023877-PA Oryza indica 56 2e-85 316
Created Date 25-Jun-2016