WERAM Information


Tag Content
WERAM ID WERAM-Hos-0221
Ensembl Protein ID ENSP00000330753.2
Uniprot Accession Q9NSI6; BRWD1_HUMAN; C9JK25; O43721; Q5R2V0; Q5R2V1; Q6P2D1; Q8TCV3; Q96QG9; Q96QH0; Q9NUK1
Genbank Protein ID NP_001007247.1; NP_061836.2; NP_387505.1
Protein Name Bromodomain and WD repeat-containing protein 1
Genbank Nucleotide ID NM_001007246.2; NM_018963.4; NM_033656.3
Gene Name BRWD1;C21orf107;WDR9
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000185658.13 ENST00000333229.6 ENSP00000330753.2
ENSG00000185658.13 ENST00000342449.7 ENSP00000344333.3
ENSG00000185658.13 ENST00000380800.7 ENSP00000370178.3
ENSG00000185658.13 ENST00000424441.1 ENSP00000415066.1
Details
Type Family Domain Substrates AA References (PMIDs)
Ac_Reader Bromodomain Bromodomain H3K9; H4K16 K 22464331; 26301565
Status Reviewed
Classification
Type Family E-value Score Start End
Ac_Reader Bromodomain 2.10e-45 154.9 1181 1398
Organism Homo sapiens
NCBI Taxa ID 9606
Functional Description
(View)
May be a transcriptional activator. May be involved in chromatin remodeling (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape.
Domain Profile
  Ac_Reader Bromodomain

          BROMO.txt    5 vsepFrepvdpqleipdYydiikePmdLstikerleegnYsspeefvkDvrlifnNakaynenkssv 71  
++ +F pvd+ +p+Y++++ P dL ti+ rl ++ Y++++ +v vr i +Na+++ne++s +
ENSP00000330753.2 1181 IAAAFAGPVDL-CTYPKYCTVVAYPTDLYTIRMRLVNRFYRRLSALVWEVRYIEHNARTFNEPESVI 1246
6889*******.9**************************************************9875 PP
BROMO.txt 2 ehevsepFrepvdpqleipdYydiikePmdLstikerleegnYsspeefvkDvrlifnNakaynenkss 70
++e+sepFr+pvd+ e+pdY+dii++Pmd+ t++e+l++gnY sp+ef kD+rlif+Nakay++nk s
ENSP00000330753.2 1331 QCEDSEPFRQPVDL-VEYPDYRDIIDTPMDFGTVRETLDAGNYDSPLEFCKDIRLIFSNAKAYTPNKRS 1398
689***********.6**************************************************987 PP

Protein Sequence
(Fasta)
MAEPSSARRP VPLIESELYF LIARYLSAGP CRRAAQVLVQ ELEQYQLLPK RLDWEGNEHN 60
RSYEELVLSN KHVAPDHLLQ ICQRIGPMLD KEIPPSISRV TSLLGAGRQS LLRTAKDCRH 120
TVWKGSAFAA LHRGRPPEMP VNYGSPPNLV EIHRGKQLTG CSTFSTAFPG TMYQHIKMHR 180
RILGHLSAVY CVAFDRTGHR IFTGSDDCLV KIWSTHNGRL LSTLRGHSAE ISDMAVNYEN 240
TMIAAGSCDK IIRVWCLRTC APVAVLQGHT GSITSLQFSP MAKGSQRYMV STGADGTVCF 300
WQWDLESLKF SPRPLKFTEK PRPGVQMLCS SFSVGGMFLA TGSTDHVIRM YFLGFEAPEK 360
IAELESHTDK VDSIQFCNNG DRFLSGSRDG TARIWRFEQL EWRSILLDMA TRISGDLSSE 420
EERFMKPKVT MIAWNQNDSI VVTAVNDHVL KVWNSYTGQL LHNLMGHADE VFVLETHPFD 480
SRIMLSAGHD GSIFIWDITK GTKMKHYFNM IEGQGHGAVF DCKFSQDGQH FACTDSHGHL 540
LIFGFGCSKP YEKIPDQMFF HTDYRPLIRD SNNYVLDEQT QQAPHLMPPP FLVDVDGNPH 600
PTKYQRLVPG RENSADEHLI PQLGYVATSD GEVIEQIISL QTNDNDERSP ESSILDGMIR 660
QLQQQQDQRM GADQDTIPRG LSNGEETPRR GFRRLSLDIQ SPPNIGLRRS GQVEGVRQMH 720
QNAPRSQIAT ERDLQAWKRR VVVPEVPLGI FRKLEDFRLE KGEEERNLYI IGRKRKTLQL 780
SHKSDSVVLV SQSRQRTCRR KYPNYGRRNR SWRELSSGNE SSSSVRHETS CDQSEGSGSS 840
EEDEWRSDRK SESYSESSSD SSSRYSDWTA DAGINLQPPL RTSCRRRITR FCSSSEDEIS 900
TENLSPPKRR RKRKKENKPK KENLRRMTPA ELANMEHLYE FHPPVWITDT TLRKSPFVPQ 960
MGDEVIYFRQ GHEAYIEAVR RNNIYELNPN KEPWRKMDLR DQELVKIVGI RYEVGPPTLC 1020
CLKLAFIDPA TGKLMDKSFS IRYHDMPDVI DFLVLRQFYD EARQRNWQSC DRFRSIIDDA 1080
WWFGTVLSQE PYQPQYPDSH FQCYIVRWDN TEIEKLSPWD MEPIPDNVDP PEELGASISV 1140
TTDELEKLLY KPQAGEWGQK SRDEECDRII SGIDQLLNLD IAAAFAGPVD LCTYPKYCTV 1200
VAYPTDLYTI RMRLVNRFYR RLSALVWEVR YIEHNARTFN EPESVIARSA KKITDQLLKF 1260
IKNQHCTNIS ELSNTSENDE QNAEDLDDSD LPKTSSGRRR VHDGKKSIRA TNYVESNWKK 1320
QCKELVNLIF QCEDSEPFRQ PVDLVEYPDY RDIIDTPMDF GTVRETLDAG NYDSPLEFCK 1380
DIRLIFSNAK AYTPNKRSKI YSMTLRLSAL FEEKMKKISS DFKIGQKFNE KLRRSQRFKQ 1440
RQNCKGDSQP NKSIRNLKPK RLKSQTKIIP ELVGSPTQST SSRTAYLGTH KTSAGISSGV 1500
TSGDSSDSAE SSERRKRNRP ITNGSTLSES EVEDSLATSL SSSASSSSEE SKESSRARES 1560
SSRSGLSRSS NLRVTRTRAA QRKTGPVSLA NGCGRKATRK RVYLSDSDNN SLETGEILKA 1620
RAGNNRKVLR KCAAVAANKI KLMSDVEENS SSESVCSGRK LPHRNASAVA RKKLLHNSED 1680
EQSLKSEIEE EELKDENQLL PVSSSHTAQS NVDESENRDS ESESDLRVAR KNWHANGYKS 1740
HTPAPSKTKF LKIESSEEDS KSHDSDHACN RTAGPSTSVQ KLKAESISEE ADSEPGRSGG 1800
RKYNTFHKNA SFFKKTKILS DSEDSESEEQ DREDGKCHKM EMNPISGNLN CDPIAMSQCS 1860
SDHGCETDLD SDDDKIEKPN NFMKDSASQD NGLSRKISRK RVCSSDSDSS LQVVKKSSKA 1920
RTGLLRITRR CAATAANKIK LMSDVEDVSL ENVHTRSKNG RKKPLHLACT TAKKKLSDCE 1980
GSVHCEVPSE QYACEGKPPD PDSEGSTKVL SQALNGDSDS EDMLNSEHKH RHTNIHKIDA 2040
PSKRKSSSVT SSGEDSKSHI PGSETDRTFS SESTLAQKAT AENNFEVELN YGLRRWNGRR 2100
LRTYGKAPFS KTKVIHDSQE TAEKEVKRKR SHPELENVKI SETTGNSKFR PDTSSKSSDL 2160
GSVTESDIDC TDNTKTKRRK TKGKAKVVRK EFVPRDREPN TKVRTCMHNQ KDAVQMPSET 2220
LKAKMVPEKV PRRCATVAAN KIKIMSNLKE TISGPENVWI RKSSRKLPHR NASAAAKKKL 2280
LNVYKEDDTT INSESEKELE DINRKMLFLR GFRSWKENAQ
Nucleotide Sequence
(Fasta)
AGGTCTTTGC CTCCGCGTCA CTTTCTCCTC ATCGAGTCCC CGGAGGCAGA GAGCTGAGCG 60
AGGTTCGCCT CCCCGGGCGG GACACGAGCT CCGGTCCTCT CTTGGCGCAA ACCCCCGCCC 120
CCCGCGGAGG GACTACTTTT CGTCTCCCGC GGAGGAACTA CTTCCTCCCC CGCGGAGGCG 180
TCGGTCCAGG CGGCGCGCAC GGTATGGCGG CGGCGGCGGC GGCGGCGGCG CGCGCCTGAG 240
AAGAGGGGAC GCCAGCCCGG TCAGGCCTCG GCGCGGCCTA CACGCTCCGC TCGCTCGCTC 300
GCTCCCGCCT CCCGCCCCGC GCCCGGCCAT GGCGGAGCCG TCGTCCGCCC GACGCCCGGT 360
GCCTCTCATC GAGTCGGAGC TGTACTTCCT TATCGCCCGG TACCTATCGG CGGGCCCGTG 420
TCGGAGAGCG GCCCAGGTGC TGGTGCAGGA GCTGGAGCAG TACCAGTTGT TGCCGAAGAG 480
ATTGGACTGG GAGGGCAACG AGCACAACAG GAGCTACGAG GAGTTGGTCT TGTCCAATAA 540
GCATGTGGCT CCTGATCATC TTTTGCAAAT CTGCCAGCGC ATCGGTCCTA TGTTGGATAA 600
AGAAATTCCA CCCAGTATTT CAAGAGTCAC TTCTTTACTT GGTGCAGGAA GGCAGTCTTT 660
GCTACGTACA GCAAAAGACT GCAGGCACAC AGTTTGGAAG GGCTCTGCCT TTGCTGCTCT 720
TCATAGAGGA AGACCTCCTG AAATGCCAGT GAATTATGGT TCCCCACCAA ATCTTGTGGA 780
GATACATCGA GGAAAACAAC TCACAGGGTG TTCCACTTTT AGTACAGCAT TTCCAGGAAC 840
TATGTATCAG CATATAAAAA TGCACAGAAG GATTCTCGGA CATCTATCTG CTGTTTACTG 900
TGTAGCATTT GATAGGACAG GACATAGAAT CTTTACAGGT TCAGATGACT GTTTGGTAAA 960
GATTTGGTCA ACACATAATG GCCGCTTGTT ATCTACATTA AGAGGTCATT CTGCAGAAAT 1020
TTCAGATATG GCAGTAAACT ATGAGAATAC AATGATTGCT GCGGGGAGCT GTGATAAAAT 1080
TATTAGAGTG TGGTGCTTGA GAACTTGTGC CCCAGTTGCT GTGCTCCAAG GACACACAGG 1140
ATCAATTACA TCTTTACAGT TTAGCCCGAT GGCCAAAGGC TCTCAAAGAT ACATGGTTTC 1200
CACTGGTGCT GATGGGACAG TTTGCTTTTG GCAATGGGAT TTAGAATCCT TAAAATTTAG 1260
CCCACGTCCC CTGAAGTTCA CTGAAAAGCC TAGGCCAGGC GTTCAAATGC TTTGTTCTTC 1320
TTTTAGTGTT GGTGGTATGT TTTTAGCCAC AGGTAGTACT GATCATGTAA TCAGAATGTA 1380
TTTTTTGGGT TTTGAAGCAC CCGAAAAAAT CGCAGAACTT GAAAGCCACA CTGATAAAGT 1440
AGATAGTATC CAATTTTGTA ACAATGGTGA TCGGTTCCTA AGTGGTAGCA GAGATGGAAC 1500
AGCACGGATT TGGAGATTTG AGCAGTTAGA ATGGAGGAGC ATTTTATTGG ATATGGCTAC 1560
CAGAATCTCA GGGGACTTAT CTTCCGAAGA GGAAAGGTTT ATGAAACCTA AAGTAACAAT 1620
GATAGCTTGG AATCAAAATG ATAGCATTGT TGTCACAGCT GTGAATGATC ATGTCCTCAA 1680
AGTGTGGAAT TCTTACACTG GACAACTGCT TCATAACTTA ATGGGACATG CTGATGAAGT 1740
ATTTGTTCTG GAGACACATC CCTTTGATTC CAGAATTATG TTATCTGCAG GACATGATGG 1800
CAGCATATTT ATATGGGATA TTACAAAAGG TACCAAGATG AAACATTATT TTAATATGAT 1860
TGAAGGACAA GGACATGGAG CTGTGTTTGA CTGTAAGTTT TCACAGGATG GACAGCATTT 1920
TGCCTGTACA GATTCTCATG GGCACCTTCT GATATTTGGT TTTGGATGCA GCAAACCATA 1980
TGAAAAGATT CCTGATCAGA TGTTCTTCCA TACTGACTAT CGACCACTTA TTAGAGATTC 2040
TAATAATTAT GTCTTAGATG AGCAAACTCA GCAGGCTCCT CATCTTATGC CTCCACCATT 2100
CTTGGTAGAT GTAGATGGAA ATCCTCATCC AACCAAGTAT CAGAGATTAG TACCAGGCCG 2160
AGAAAATTCT GCAGATGAAC ATTTGATTCC ACAGCTGGGC TATGTGGCAA CAAGTGATGG 2220
AGAGGTGATT GAACAAATTA TAAGCCTGCA AACCAATGAT AATGATGAAC GCAGCCCAGA 2280
ATCGAGTATT CTTGATGGAA TGATAAGACA GTTGCAGCAG CAGCAAGATC AGAGAATGGG 2340
AGCAGATCAG GATACTATTC CAAGAGGACT TTCAAATGGT GAAGAAACAC CCCGGAGAGG 2400
TTTTAGAAGG CTGAGCTTAG ACATTCAGTC CCCTCCAAAT ATTGGTCTGC GTCGTAGTGG 2460
ACAAGTTGAA GGTGTTCGTC AGATGCATCA AAACGCTCCA CGCAGTCAGA TTGCTACAGA 2520
ACGTGACCTG CAGGCTTGGA AACGAAGAGT GGTTGTACCA GAGGTACCAC TAGGCATATT 2580
TAGGAAGCTG GAAGACTTCC GATTAGAGAA AGGTGAAGAG GAAAGAAATC TTTATATAAT 2640
AGGAAGAAAA AGAAAGACTC TTCAGCTCTC ACATAAGTCG GATTCAGTGG TTTTGGTATC 2700
ACAGTCTAGA CAAAGGACAT GTAGGCGTAA ATATCCAAAT TATGGTAGAA GAAATCGTAG 2760
CTGGCGTGAG TTATCTTCTG GAAATGAGTC TTCAAGCTCT GTAAGACATG AGACTTCCTG 2820
TGATCAGAGT GAAGGTTCTG GTTCTTCAGA AGAGGATGAA TGGAGAAGTG ACAGAAAAAG 2880
TGAGAGTTAC AGCGAAAGTT CAAGTGACTC TTCATCTAGA TATTCCGATT GGACAGCTGA 2940
TGCGGGCATC AATTTGCAGC CTCCTTTAAG AACATCATGT CGTCGACGAA TTACTCGATT 3000
TTGTAGTAGT TCAGAAGATG AAATATCTAC TGAGAATTTA TCTCCTCCAA AAAGAAGACG 3060
AAAGAGAAAG AAAGAAAATA AGCCTAAGAA GGAGAATTTG CGGAGGATGA CTCCAGCAGA 3120
GCTTGCAAAT ATGGAGCATT TATATGAATT TCACCCTCCA GTTTGGATTA CTGACACCAC 3180
ACTTAGAAAA TCTCCTTTTG TTCCTCAAAT GGGTGATGAG GTAATATATT TTCGACAGGG 3240
TCATGAAGCT TATATTGAGG CTGTAAGAAG AAATAATATT TATGAACTGA ACCCTAATAA 3300
GGAGCCATGG AGAAAAATGG ATCTTAGGGA TCAAGAATTG GTTAAAATAG TTGGAATACG 3360
ATATGAAGTT GGGCCCCCTA CACTCTGTTG CCTAAAACTA GCATTTATAG ATCCAGCAAC 3420
TGGAAAACTT ATGGACAAAT CTTTCTCTAT TAGATATCAT GATATGCCAG ATGTTATTGA 3480
CTTTCTTGTA TTGCGTCAAT TTTATGATGA AGCAAGACAG AGGAATTGGC AGTCTTGTGA 3540
CAGATTCCGC TCTATTATTG ATGATGCTTG GTGGTTTGGA ACAGTGTTAA GTCAAGAGCC 3600
ATATCAACCA CAGTATCCTG ATAGTCATTT CCAGTGTTAT ATTGTTAGGT GGGATAATAC 3660
TGAAATTGAA AAACTTAGCC CATGGGACAT GGAACCAATT CCTGATAATG TTGATCCACC 3720
TGAAGAATTA GGAGCTAGTA TTTCTGTCAC AACAGATGAG CTAGAGAAAT TGCTCTATAA 3780
ACCACAAGCT GGTGAATGGG GTCAGAAATC AAGAGATGAA GAATGTGATA GAATTATCAG 3840
TGGTATAGAT CAACTTTTGA ATCTTGATAT AGCAGCAGCT TTTGCAGGCC CTGTTGATTT 3900
GTGTACATAC CCGAAGTACT GTACTGTAGT AGCTTATCCA ACCGATCTTT ACACAATTCG 3960
AATGAGACTT GTTAATCGAT TTTACAGGAG GCTGTCTGCG TTAGTTTGGG AAGTCAGATA 4020
TATAGAACAT AATGCCAGAA CATTTAACGA ACCTGAGAGT GTAATTGCAA GATCAGCTAA 4080
AAAGATAACT GACCAACTTT TAAAATTTAT CAAGAATCAA CACTGTACAA ATATCTCAGA 4140
ACTTTCTAAC ACATCTGAAA ATGATGAGCA AAATGCTGAG GATTTGGATG ATAGTGATCT 4200
TCCTAAAACA TCTTCTGGAA GGAGGAGAGT CCATGATGGG AAAAAAAGCA TCAGAGCTAC 4260
GAACTATGTT GAAAGCAACT GGAAGAAACA GTGTAAGGAA CTAGTGAACT TAATTTTTCA 4320
GTGTGAAGAT TCTGAACCAT TTAGACAACC TGTTGATTTG GTTGAATATC CAGACTACAG 4380
AGATATTATA GATACCCCAA TGGATTTTGG AACAGTAAGG GAAACTCTAG ATGCGGGAAA 4440
TTATGACAGC CCTTTGGAGT TTTGCAAAGA CATCCGGCTG ATATTTAGCA ATGCAAAAGC 4500
GTATACACCA AACAAAAGAT CAAAGATTTA TAGTATGACC TTGAGATTAT CTGCCTTATT 4560
TGAAGAAAAA ATGAAGAAAA TCTCTTCTGA TTTTAAAATT GGTCAAAAAT TCAATGAAAA 4620
ACTTCGAAGA AGCCAGAGGT TCAAGCAACG GCAAAATTGT AAAGGTGACA GTCAGCCTAA 4680
CAAAAGTATC AGAAACCTCA AGCCGAAGAG GTTAAAATCT CAGACAAAAA TAATTCCTGA 4740
GTTGGTAGGT TCTCCTACCC AGTCTACCTC AAGTAGGACA GCTTATCTTG GAACCCACAA 4800
GACAAGTGCT GGTATCTCTT CAGGTGTTAC TTCTGGTGAC TCTTCAGATT CAGCAGAATC 4860
ATCAGAAAGG AGGAAAAGAA ATAGACCTAT AACAAATGGT TCTACATTAT CTGAAAGTGA 4920
AGTGGAAGAT TCTTTAGCTA CCTCTTTGTC ATCGTCAGCT TCCAGTAGTT CTGAGGAAAG 4980
CAAAGAGAGT TCCAGAGCTC GTGAATCCTC CTCACGCAGT GGGCTATCCA GAAGCAGCAA 5040
TCTCAGGGTA ACCAGAACTA GAGCTGCTCA AAGAAAAACT GGTCCCGTTT CATTAGCAAA 5100
TGGATGTGGC AGAAAAGCCA CTCGAAAGAG AGTCTATTTA AGTGATTCTG ATAACAATTC 5160
ATTGGAGACT GGTGAAATTC TAAAAGCCAG AGCTGGAAAT AACCGAAAAG TCTTAAGGAA 5220
GTGTGCTGCT GTGGCTGCCA ATAAAATAAA GCTAATGAGT GATGTAGAAG AGAATTCTAG 5280
CTCTGAAAGT GTCTGTTCTG GTCGGAAGCT GCCTCACCGC AATGCTTCTG CTGTAGCTAG 5340
AAAAAAGTTA TTACATAATT CTGAAGATGA ACAGAGCTTA AAGTCAGAAA TTGAAGAAGA 5400
GGAGCTAAAA GATGAAAATC AACTATTACC AGTGTCCAGT TCTCACACTG CCCAGAGCAA 5460
TGTTGATGAA TCTGAAAACA GAGACTCAGA GTCAGAAAGT GATTTGCGGG TAGCCCGGAA 5520
AAATTGGCAT GCTAATGGTT ACAAGTCCCA TACTCCAGCA CCTTCAAAGA CAAAATTTCT 5580
TAAAATAGAG TCTTCTGAGG AAGACTCTAA AAGTCATGAT TCAGATCATG CATGTAACAG 5640
AACTGCTGGC CCATCAACGT CTGTGCAGAA ACTTAAGGCA GAGAGCATCT CAGAGGAAGC 5700
AGATTCTGAA CCAGGAAGAT CTGGTGGTAG GAAATACAAT ACATTTCACA AGAATGCGAG 5760
TTTCTTTAAA AAAACCAAGA TTCTGAGTGA CTCAGAAGAC TCTGAATCTG AAGAGCAAGA 5820
TAGAGAAGAT GGGAAATGTC ATAAAATGGA AATGAACCCA ATTTCAGGAA ATCTGAACTG 5880
TGACCCTATT GCTATGTCCC AGTGTTCCTC AGATCATGGA TGTGAAACTG ATTTAGATTC 5940
AGATGATGAC AAAATAGAAA AACCAAACAA TTTTATGAAA GATTCTGCAT CACAAGACAA 6000
TGGACTAAGC AGAAAAATTT CCAGGAAAAG GGTCTGTTCC AGTGACTCAG ACAGTAGTTT 6060
ACAGGTGGTT AAGAAATCAT CAAAAGCCAG AACAGGTCTC CTGAGGATTA CTCGAAGATG 6120
TGCAGCTACG GCTGCCAATA AGATCAAGCT CATGAGTGAT GTAGAAGATG TCAGTTTAGA 6180
AAATGTGCAC ACTAGAAGCA AAAATGGAAG GAAAAAACCT CTCCATCTTG CTTGTACTAC 6240
AGCTAAGAAG AAATTGAGTG ATTGTGAAGG AAGTGTACAT TGTGAAGTAC CAAGTGAACA 6300
GTATGCCTGT GAAGGCAAGC CACCTGATCC TGACTCCGAA GGTAGTACAA AAGTGCTTAG 6360
TCAGGCTCTA AATGGAGACT CAGACTCTGA AGATATGTTG AATTCAGAAC ACAAGCACAG 6420
GCATACCAAT ATTCACAAAA TAGATGCACC TTCTAAAAGA AAAAGTTCCT CTGTTACATC 6480
TTCAGGAGAA GATTCAAAAA GTCATATTCC AGGGAGTGAG ACTGATAGGA CATTTTCTTC 6540
AGAGTCAACC TTGGCACAAA AAGCTACTGC AGAGAATAAT TTTGAAGTGG AACTGAATTA 6600
TGGGCTGCGC AGGTGGAATG GCAGAAGACT CAGGACCTAT GGAAAGGCTC CTTTTAGTAA 6660
GACAAAAGTG ATTCATGATT CACAGGAAAC AGCAGAGAAG GAAGTAAAAA GGAAGAGATC 6720
GCATCCTGAA TTGGAAAATG TGAAAATCTC TGAAACAACT GGGAATTCAA AGTTTAGACC 6780
TGATACTAGT TCCAAATCAT CAGATTTGGG ATCTGTAACT GAATCAGATA TTGACTGTAC 6840
TGATAATACA AAAACCAAAA GGAGGAAAAC GAAAGGAAAA GCAAAAGTAG TTAGAAAAGA 6900
ATTTGTTCCT AGAGACAGAG AACCCAATAC AAAAGTGAGA ACATGTATGC ATAATCAGAA 6960
GGATGCAGTG CAGATGCCTA GTGAAACTCT GAAAGCAAAA ATGGTACCTG AGAAAGTTCC 7020
CCGCAGATGT GCTACTGTTG CTGCAAATAA AATAAAGATA ATGAGTAATC TAAAAGAAAC 7080
GATCTCAGGA CCAGAAAATG TCTGGATTAG GAAGAGTAGC AGAAAACTGC CCCATCGAAA 7140
TGCTTCTGCT GCGGCTAAGA AAAAATTACT GAATGTTTAT AAAGAGGATG ATACAACCAT 7200
AAATTCTGAA AGTGAAAAAG AGCTAGAAGA TATTAATAGA AAAATGCTTT TTTTAAGGGG 7260
GTTCAGATCC TGGAAAGAAA ATGCACAATA GTGACTATGA GAATGTAGAA GTGGCATCTG 7320
AAAACAATTG GTACACAAGT AAACTGGCAG TTACATTCTG CTCCCAGCTC TAAAATTACT 7380
CCCTTATTGG CATCTTTGGA GGAATTTTCT AAAAGCCATA ATCCAGTGGG TTCCTCCCAG 7440
TCAGCTCTTG TACAGACATG TGCTCTGGGG AATTCTGAGG AGGAAATAAA TTGCAGAGTC 7500
TGTAGGTGGA GAGGTGGAAA GAAAAGACAA ATGGCCTGCT ATAAGACTAC TATTCCTTTC 7560
CAGAATGCAA GGCCTTGAAG ACATGATTCC TTAGAGGAAG AATATAATGG GAAGTGTACA 7620
GGCTAGGAAG AACTTGAAGT GAACAAATTT CAAAATCTTA ACCTGATGCT AATTTTCAGG 7680
GTTCTCCATT ACAGTGTAAA AATTCAGACC ACGACAACTA TGGTGTCATG AGGAAAAAAA 7740
ATCAGGCATT TTTCCAAAGG AAGTGCTAAT GGGCCTATTT GACTTCTGAG TGAAGCAAAA 7800
ACTACCCAGA TCCATTCCCT ACAATTCACA TCCCCAAAGG TCAAAAACAA ACTAGGAGGA 7860
CCTGGGAATT TCAGCTGGAG ATACTGATTA TTGAGTTCTG AAGTAGAGTG TTGGAAATAG 7920
GCAATTAGAG AAAGTCCATT GATGTCATTT TGTTTATAAT ATTGCAGTTC ATACTGAATG 7980
ACCACTTGAT ATGACTAATT CAGGGAATAT ATATTTTTCT ATGAAAGCTA TGAATGTTAC 8040
TATCACGGCT TTTCCTTATT TTTACTTGTA TGTAGCAGCA TTTACAGAAA TGCCAAAAAT 8100
GTGCCTCATT AAGAGGCAGG TCTTAATCAG TTAGATAAAA ATAAAATGTA TAGCTTAAGA 8160
TCAAAACAGT CATATTTTTA GATACAGTGA AATCTTTTAT GTTTCTCTAC AGCACCTTAA 8220
AAATTAGAAC TTGAATACTT TGAGTAAACT TACTACAATC TCATCCCAAC AAACTTTAAT 8280
GGTAGCATGT TTGGCCTATT TCATTGTGGC CTGTACTAGG ATTAGAAAAT TTGGTCGTGG 8340
TATAACAAAG AAGTGTATTT ACAATAGGAT TTAATTTGTT GTTAATATGT ATTTGTTGAA 8400
ATTAAAATTG CCAGATTAAA TGAATATACT GTCGCATCTT TTTAACATAG TAACGTGTTA 8460
CTGGAAAAAT TAAGTTGTTG AAAGTAAGTT GTTTTCCCAT TTAAAAATAT CTGAATATAT 8520
GATTTGCATG TGTAAATCTG AAAAACTAAA CTACAGAAAC CTAGGGTTTT CTATTTCTTT 8580
TTTAAGTCAA ATGCATTTTT TTTTTTTTGT TATACAGATG AACCAAGTGT CTAAAATACT 8640
TGAGAAATTT GTGGTTGCAT GTCTGTTTTA AAAAAAAGGC TTTTTGTTTT TTAGCATAAG 8700
CCAGAATATT CTAACCTACT AAGTCTGTGT CCTTTGCTCC TTTTGTAGTA TACTTTCATC 8760
TAAATTACTG ATCCCCAATA TGTTGATACA CAGGTGAGAA AGGGAAGAAT TCCTAATAAA 8820
CTGCTATTAC TTTTAGGTGC ATGGGGTTTG ATTTTTGAGC TCTAATGAAA TGCTTAAACT 8880
TCTTTCCAGT TCAAATTTTA CACTTAATTT ATAATATTTA TTGAGTATAT TATGTCCTCA 8940
ACAAGTAACT ATAAAATGAA ATACTTAACT CGGTGAAGAC TATTTTATGC AAAGTTTTTT 9000
TTTTTTTTTT TTTTTTTTTT TAGCAATTTC AGTGTAATGA AAGAATTTAA GCTTTGAATT 9060
TATAATTTGC TGTGGTGGGG TTAATTTCTG TCAGTATTTG AGATTGTATT ATCAGTCTTG 9120
CATAATGAAA TCCTTTTTTG GCTAAGTATT TAATTCGAAC ATATTTGCCT TTTTAAAAAG 9180
TGCTTGGCCT AAACTTATTG TAACTGCATG AAATAAGCAT TTGCTTAAAA CTTAACATTG 9240
TAAAATTGTT CTCTCTGAAA TGTGTGCAGA ATTTAAATCA TGGCCAAATG TATTACTATT 9300
ACCCTATTTA CAGTAATTTG CTTTGCAGAA AATATTTCTT CATCATGGAA CTGTGAAATC 9360
AAATTGAAGA TCTTACTGGT AAAAATGACA AATTAACAAA AGGACTAAGA CAAGTGGTGC 9420
CCAAACAACC TTTTTATTCT GCAGTTCCAT CATCATAATA GACCAGTTAA CCCAGGAGTC 9480
CTAATGTTTT AAAACATCAT TGTGGTGATC TTGTTTATTC TATCTCACTA AGGATATCCA 9540
GTTTCCTAAG CTCTTACTGG CTAGCAATTT CGTCTTAATT TTATTGCTAA ATGTTCAAAT 9600
TTTGCTTCCA AACTCACTTT ATTTTTGCAG ATGTGTACAT CTGCTAAGTA CTAATTTTAT 9660
GTAAATGATT TTGTTGATTA TCTTTCCACA TCTTAAAATG TTTCTAACAG CTTTGAGATT 9720
TTATCTCAAC AGGCTCTCTC TGACCCCAAA GTAGTACTTA CCTTCGTGAC TACTGACAAA 9780
GTCACAAAAT GCAGGCGATG TCATGTATTT CGGTACAACT AAATCTAGGA AACGGTTTTT 9840
TCATTGCATT ACTGCATATT TTCATTTTCA TTTAAATTAT GTCCCCTTTT TCTCTTGCTT 9900
GAAACAGTGC TCCTCGAACT TTGTCTTCCA GCACATTTTA AAGAGAACCA ATTAAAGAAC 9960
AATCACACAT TCTGCTTATT AAAGGCTATT TAAAAAGAAA CATTTTGTAT TAGAAAATGG 10020
CCAACTTTAA AACACTATTT TTTACACTCA TAAAAATGTT TTTTAAATCG CCTTGACAAT 10080
CATCAGCTTT TGAAATGTGA ATTCCTATTG CCAGAGTAAA GGTCTCGTTT TTATACCACC 10140
A 10142
Sequence Source Ensembl
Keyword

KW-0002--3D-structure
KW-0010--Activator
KW-0025--Alternative splicing
KW-0103--Bromodomain
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0677--Repeat
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0853--WD repeat
--

Interpro

IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00439--Bromodomain
PF00400--WD40

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005730--C:nucleolus
GO:0005634--C:nucleus
GO:0007010--P:cytoskeleton organization
GO:0008360--P:regulation of cell shape
GO:0006357--P:regulation of transcription from RNA polymerase II promoter
GO:0006351--P:transcription, DNA-templated

Orthology
WERAM ID Ensembl Protein ID Species Identity E-value Score
WERAM-Pat-0113 ENSPTRP00000023944.2 Pan troglodytes 99 0.0 4174
WERAM-Gog-0027 ENSGGOP00000002515.2 Gorilla gorilla 99 0.0 4138
WERAM-Mam-0067 ENSMMUP00000011148.2 Macaca mulatta 98 0.0 4110
WERAM-Paa-0111 ENSPANP00000012971.1 Papio anubis 97 0.0 4092
WERAM-Poa-0096 ENSPPYP00000012751.1 Pongo abelii 98 0.0 4039
WERAM-Chs-0098 ENSCSAP00000004683.1 Chlorocebus sabaeus 98 0.0 3853
WERAM-Caj-0153 ENSCJAP00000000500.2 Callithrix jacchus 95 0.0 3804
WERAM-Bot-0127 ENSBTAP00000018087.5 Bos taurus 88 0.0 3705
WERAM-Caf-0112 ENSCAFP00000014769.3 Canis familiaris 89 0.0 3672
WERAM-Eqc-0185 ENSECAP00000020111.1 Equus caballus 90 0.0 3630
WERAM-Orc-0085 ENSOCUP00000007670.3 Oryctolagus cuniculus 88 0.0 3629
WERAM-Loa-0140 ENSLAFP00000012652.3 Loxodonta africana 87 0.0 3589
WERAM-Ptv-0172 ENSPVAP00000014795.1 Pteropus vampyrus 88 0.0 3559
WERAM-Ova-0101 ENSOARP00000010334.1 Ovis aries 86 0.0 3545
WERAM-Dan-0101 ENSDNOP00000010916.3 Dasypus novemcinctus 85 0.0 3536
WERAM-Cap-0122 ENSCPOP00000009683.2 Cavia porcellus 83 0.0 3502
WERAM-Tut-0170 ENSTTRP00000014567.1 Tursiops truncatus 87 0.0 3487
WERAM-Myl-0066 ENSMLUP00000005612.2 Myotis lucifugus 86 0.0 3435
WERAM-Vip-0068 ENSVPAP00000006198.1 Vicugna pacos 87 0.0 3398
WERAM-Aim-0160 ENSAMEP00000014853.1 Ailuropoda melanoleuca 85 0.0 3356
WERAM-Ran-0016 ENSRNOP00000002231.5 Rattus norvegicus 78 0.0 3237
WERAM-Mum-0050 ENSMUSP00000097101.2 Mus musculus 78 0.0 3231
WERAM-Nol-0146 ENSNLEP00000015923.1 Nomascus leucogenys 98 0.0 3088
WERAM-Fec-0213 ENSFCAP00000025404.1 Felis catus 83 0.0 3082
WERAM-Mup-0090 ENSMPUP00000008450.1 Mustela putorius furo 90 0.0 3022
WERAM-Otg-0099 ENSOGAP00000008563.2 Otolemur garnettii 87 0.0 2969
WERAM-Ora-0069 ENSOANP00000010247.1 Ornithorhynchus anatinus 70 0.0 2864
WERAM-Mod-0188 ENSMODP00000026232.4 Monodelphis domestica 70 0.0 2732
WERAM-Gaga-0146 ENSGALP00000025835.4 Gallus gallus 63 0.0 2402
WERAM-Tag-0073 ENSTGUP00000005249.1 Taeniopygia guttata 74 0.0 2363
WERAM-Fia-0069 ENSFALP00000005240.1 Ficedula albicollis 70 0.0 2357
WERAM-Meg-0147 ENSMGAP00000015414.2 Meleagris gallopavo 73 0.0 2337
WERAM-Pes-0042 ENSPSIP00000006404.1 Pelodiscus sinensis 61 0.0 2209
WERAM-Lac-0108 ENSLACP00000013539.1 Latimeria chalumnae 67 0.0 2132
WERAM-Anp-0130 ENSAPLP00000014499.1 Anas platyrhynchos 59 0.0 2066
WERAM-Anc-0052 ENSACAP00000005524.3 Anolis carolinensis 61 0.0 2035
WERAM-Tas-0092 ENSTSYP00000009706.1 Tarsius syrichta 90 0.0 2004
WERAM-Leo-0154 ENSLOCP00000018481.1 Lepisosteus oculatus 60 0.0 1754
WERAM-Soa-0064 ENSSARP00000006479.1 Sorex araneus 81 0.0 1736
WERAM-Dar-0037 ENSDARP00000018130.6 Danio rerio 58 0.0 1680
WERAM-Tar-0005 ENSTRUP00000001375.1 Takifugu rubripes 59 0.0 1674
WERAM-Orn-0014 ENSONIP00000001313.1 Oreochromis niloticus 59 0.0 1665
WERAM-Orla-0107 ENSORLP00000012981.1 Oryzias latipes 58 0.0 1665
WERAM-Ten-0114 ENSTNIP00000012568.1 Tetraodon nigroviridis 58 0.0 1640
WERAM-Gaa-0217 ENSGACP00000026878.2 Gasterosteus aculeatus 56 0.0 1639
WERAM-Mim-0118 ENSMICP00000012073.1 Microcebus murinus 83 0.0 1587
WERAM-Sah-0027 ENSSHAP00000002885.1 Sarcophilus harrisii 87 0.0 1466
WERAM-Chh-0023 ENSCHOP00000002306.1 Choloepus hoffmanni 80 0.0 1432
WERAM-Tub-0104 ENSTBEP00000012018.1 Tupaia belangeri 80 0.0 1376
WERAM-Prc-0058 ENSPCAP00000005712.1 Procavia capensis 71 0.0 1154
WERAM-Asm-0127 ENSAMXP00000012597.1 Astyanax mexicanus 70 0.0 1145
WERAM-Ict-0191 ENSSTOP00000022603.1 Ictidomys tridecemlineatus 96 0.0 1137
WERAM-Xim-0009 ENSXMAP00000001252.1 Xiphophorus maculatus 70 0.0 1111
WERAM-Mae-0110 ENSMEUP00000010547.1 Macropus eugenii 80 0.0 1110
WERAM-Xet-0079 ENSXETP00000025715.4 Xenopus tropicalis 66 0.0 1075
WERAM-Pof-0006 ENSPFOP00000000952.2 Poecilia formosa 62 0.0 1012
WERAM-Ect-0083 ENSETEP00000009469.1 Echinops telfairi 73 0.0 974
WERAM-Sus-0029 ENSSSCP00000004824.2 Sus scrofa 55 0.0 940
WERAM-Ere-0133 ENSEEUP00000014027.1 Erinaceus europaeus 57 0.0 924
WERAM-Dio-0125 ENSDORP00000011981.1 Dipodomys ordii 59 0.0 894
WERAM-Drm-0016 FBpp0083988 Drosophila melanogaster 50 0.0 656
WERAM-Ocp-0001 ENSOPRP00000000332.1 Ochotona princeps 60 8e-161 566
WERAM-Gam-0106 ENSGMOP00000011171.1 Gadus morhua 54 4e-157 554
WERAM-Cii-0032 ENSCINP00000012790.3 Ciona intestinalis 39 1e-107 390
WERAM-Pem-0055 ENSPMAP00000006254.1 Petromyzon marinus 55 1e-78 293
WERAM-Viv-0028 VIT_05s0077g01160.t01 Vitis vinifera 31 1e-77 290
WERAM-Bro-0130 Bo7g092740.1 Brassica oleracea 31 2e-77 289
WERAM-Brr-0054 Bra010036.1-P Brassica rapa 31 5e-77 288
WERAM-Arl-0008 Al_scaffold_0004_3445 Arabidopsis lyrata 31 2e-75 282
WERAM-Art-0060 AT2G47410.1 Arabidopsis thaliana 32 3e-75 282
WERAM-Glm-0194 GLYMA15G15220.2 Glycine max 30 2e-74 280
WERAM-Thc-0058 EOY06689 Theobroma cacao 31 5e-74 278
WERAM-Mua-0028 GSMUA_Achr11P20690_001 Musa acuminata 31 8e-74 277
WERAM-Tra-0184 Traes_5AS_1F04E10C7.2 Triticum aestivum 30 1e-73 277
WERAM-Prp-0095 EMJ23094 Prunus persica 30 1e-73 277
WERAM-Pot-0117 POPTR_0010s15260.1 Populus trichocarpa 31 3e-71 269
WERAM-Amt-0066 ERN16745 Amborella trichopoda 30 4e-71 268
WERAM-Php-0039 PP1S19_18V6.1 Physcomitrella patens 30 1e-69 263
WERAM-Osl-0029 ABO94205 Ostreococcus lucimarinus 29 2e-55 216
WERAM-Lab-0060 EDR06536 Laccaria bicolor 28 6e-33 142
WERAM-Scs-0019 EDO03008 Sclerotinia sclerotiorum 28 8e-33 141
WERAM-Ast-0012 CADATEAP00004711 Aspergillus terreus 29 3e-30 133
WERAM-Pytr-0032 EDU43562 Pyrenophora triticirepentis 28 7e-28 125
WERAM-Trv-0005 EHK19841 Trichoderma virens 30 1e-27 124
WERAM-Asfu-0041 CADAFUAP00009381 Aspergillus fumigatus 29 8e-27 121
WERAM-Chg-0036 EAQ86947 Chaetomium globosum 28 2e-25 116
WERAM-Sol-0007 Solyc01g060040.2.1 Solanum lycopersicum 29 2e-24 113
WERAM-Asn-0014 CADANIAP00002953 Aspergillus nidulans 26 2e-24 113
WERAM-Zyt-0022 Mycgr3P46654 Zymoseptoria tritici 27 1e-23 110
WERAM-Trr-0031 EGR47919 Trichoderma reesei 26 1e-22 107
Created Date 25-Jun-2016