Tag |
Content |
WERAM ID |
WERAM-Hos-0176 |
Ensembl Protein ID |
ENSP00000296302.7 |
Uniprot Accession |
Q86U86; PB1_HUMAN; A1L381; A1L382; A4FUJ7; Q1RMD1; Q1RMD2; Q96MS2; Q9H2T3; Q9H2T4; Q9H2T5; Q9H301; Q9H314 |
Genbank Protein ID |
NP_060783.3 |
Protein Name |
Protein polybromo-1 |
Genbank Nucleotide ID |
NM_018313.4 |
Gene Name |
PBRM1;BAF180;PB1 |
Ensembl Information |
|
Details |
Type |
Family |
Domain |
Substrates |
AA |
References (PMIDs) |
Ac_Reader |
Bromodomain |
Bromodomain |
H3K4; H3K9; H3K14; H3K18; H3K23 |
K |
22464331 |
|
Status |
Reviewed |
Classification |
Type |
Family |
E-value |
Score |
Start |
End |
Ac_Reader |
Bromodomain |
1.50e-93 |
309.1 |
69 |
862 |
|
Organism |
Homo sapiens |
NCBI Taxa ID |
9606 |
Functional Description (View)Functional Description
Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Acts as a negative regulator of cell proliferation. |
Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Acts as a negative regulator of cell proliferation.
|
Domain Profile |
Ac_Reader Bromodomain
BROMO.txt 6 sepF.repvdpqleipdYydiikePmdLstikerleegnYsspeefvkDvrlifnNakaynenkssv 71 +e F r p ++ + pdYy+++ +P+dL +i+++l+ ++Y +++ + +D++l+fnNak y++++s ENSP00000296302.7 69 CELFiRAPKRR--NQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPE 133 67785555555..9*************************************************9975 PP BROMO.txt 5 vsepFrepvdpqleipdYydiikePmdLstikerleegnYsspeefvkDvrlifnNakaynenkssv 71 +se F++ + ++pdYy iikeP+dL+ti +r+++g Y+s++ ++kD+ l+ +Nak+yne++s+v ENSP00000296302.7 204 ISELFQKLPSK-VQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQV 269 7999*776666.49*************************************************9987 PP BROMO.txt 5 vsepF.repvdpqleipdYydiikePmdLstikerleegnYsspeefvkDvrlifnNakaynenkssvq 72 ++epF + p+++ ++pdYy+ ik P+ L+ i+ +l++++Y++++ + D++l+f+Nak yn ++s ++ ENSP00000296302.7 404 IAEPFyHLPSKK--KYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIY 470 789**8888888..9************************************************999876 PP BROMO.txt 3 hevsepF.repvdpqleipdYydiikePmdLstikerleegnYsspeefvkDvrlifnNakaynenkssvq 72 +++++ F +p+++ ++pdYy+ii ePmdL+ i++++++ +Y e +++D++l+f+Na+ yne++s+v+ ENSP00000296302.7 540 RRLCDLFmVKPSKK--DYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVY 608 56677784455555..9***************************************************997 PP BROMO.txt 3 hevsepF.repvdpqleipdYydiikePmdLstikerleegnYsspeefvkDvrlifnNakaynenkssvq 72 +++s +F r p++ e+pdYy ik+Pmd+++i++ +++++Y++++ +v+D+ +fnNa +yne++s ++ ENSP00000296302.7 678 RRLSAIFlRLPSRS--ELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIY 746 78899996777777..9*************************************************99776 PP BROMO.txt 27 kePmdLstikerleegnYsspeefvkDvrlifnNakaynenkssvq 72 k P+ ++ i++++e+++Y++++ f +++ +++ a+ +n+ +s+++ ENSP00000296302.7 817 KPPLTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIY 862 579****************************************987 PP
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Protein Sequence (Fasta) | MGSKRRRATS PSSSVSGDFD DGHHSVSTPG PSRKRRRLSN LPTVDPIAVC HELYNTIRDY 60 KDEQGRLLCE LFIRAPKRRN QPDYYEVVSQ PIDLMKIQQK LKMEEYDDVN LLTADFQLLF 120 NNAKSYYKPD SPEYKAACKL WDLYLRTRNE FVQKGEADDE DDDEDGQDNQ GTVTEGSSPA 180 YLKEILEQLL EAIVVATNPS GRLISELFQK LPSKVQYPDY YAIIKEPIDL KTIAQRIQNG 240 SYKSIHAMAK DIDLLAKNAK TYNEPGSQVF KDANSIKKIF YMKKAEIEHH EMAKSSLRMR 300 TPSNLAAARL TGPSHSKGSL GEERNPTSKY YRNKRAVQGG RLSAITMALQ YGSESEEDAA 360 LAAARYEEGE SEAESITSFM DVSNPFYQLY DTVRSCRNNQ GQLIAEPFYH LPSKKKYPDY 420 YQQIKMPISL QQIRTKLKNQ EYETLDHLEC DLNLMFENAK RYNVPNSAIY KRVLKLQQVM 480 QAKKKELARR DDIEDGDSMI SSATSDTGSA KRKSKKNIRK QRMKILFNVV LEAREPGSGR 540 RLCDLFMVKP SKKDYPDYYK IILEPMDLKI IEHNIRNDKY AGEEGMIEDM KLMFRNARHY 600 NEEGSQVYND AHILEKLLKE KRKELGPLPD DDDMASPKLK LSRKSGISPK KSKYMTPMQQ 660 KLNEVYEAVK NYTDKRGRRL SAIFLRLPSR SELPDYYLTI KKPMDMEKIR SHMMANKYQD 720 IDSMVEDFVM MFNNACTYNE PESLIYKDAL VLHKVLLETR RDLEGDEDSH VPNVTLLIQE 780 LIHNLFVSVM SHQDDEGRCY SDSLAEIPAV DPNFPNKPPL TFDIIRKNVE NNRYRRLDLF 840 QEHMFEVLER ARRMNRTDSE IYEDAVELQQ FFIKIRDELC KNGEILLSPA LSYTTKHLHN 900 DVEKERKEKL PKEIEEDKLK REEEKREAEK SEDSSGAAGL SGLHRTYSQD CSFKNSMYHV 960 GDYVYVEPAE ANLQPHIVCI ERLWEDSAGE KWLYGCWFYR PNETFHLATR KFLEKEVFKS 1020 DYYNKVPVSK ILGKCVVMFV KEYFKLCPEN FRDEDVFVCE SRYSAKTKSF KKIKLWTMPI 1080 SSVRFVPRDV PLPVVRVASV FANADKGDDE KNTDNSEDSR AEDNFNLEKE KEDVPVEMSN 1140 GEPGCHYFEQ LHYNDMWLKV GDCVFIKSHG LVRPRVGRIE KVWVRDGAAY FYGPIFIHPE 1200 ETEHEPTKMF YKKEVFLSNL EETCPMTCIL GKCAVLSFKD FLSCRPTEIP ENDILLCESR 1260 YNESDKQMKK FKGLKRFSLS AKVVDDEIYY FRKPIVPQKE PSPLLEKKIQ LLEAKFAELE 1320 GGDDDIEEMG EEDSEVIEPP SLPQLQTPLA SELDLMPYTP PQSTPKSAKG SAKKEGSKRK 1380 INMSGYILFS SEMRAVIKAQ HPDYSFGELS RLVGTEWRNL ETAKKAEYEE RAAKVAEQQE 1440 RERAAQQQQP SASPRAGTPV GALMGVVPPP TPMGMLNQQL TPVAGMMGGY PPGLPPLQGP 1500 VDGLVSMGSM QPLHPGGPPP HHLPPGVPGL PGIPPPGVMN QGVAPMVGTP APGGSPYGQQ 1560 VGVLGPPGQQ APPPYPGPHP AGPPVIQQPT TPMFVAPPPK TQRLLHSEAY LKYIEGLSAE 1620 SNSISKWDQT LAARRRDVHL SKEQESRLPS HWLKSKGAHT TMADALWRLR DLMLRDTLNI 1680 RQAYNLENV 1689Protein Fasta Sequence
>ENSP00000296302.7|PBRM1;BAF180;PB1|Homo sapiens MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPAYLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHHEMAKSSLRMRTPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAALAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPISSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEERAAKVAEQQERERAAQQQQPSASPRAGTPVGALMGVVPPPTPMGMLNQQLTPVAGMMGGYPPGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALWRLRDLMLRDTLNIRQAYNLENV
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Nucleotide Sequence (Fasta) | CCATGGGTTC CAAGAGAAGA AGAGCTACCT CCCCTTCCAG CAGTGTCAGC GGGGACTTTG 60 ATGATGGGCA CCATTCTGTG TCAACACCAG GCCCAAGCAG GAAAAGGAGG AGACTTTCCA 120 ATCTTCCAAC TGTAGATCCT ATTGCCGTGT GCCATGAACT CTATAATACC ATCCGAGACT 180 ATAAGGATGA ACAGGGCAGA CTTCTCTGTG AGCTCTTCAT TAGGGCACCA AAGCGAAGAA 240 ATCAACCAGA CTATTATGAA GTGGTTTCTC AGCCCATTGA CTTGATGAAA ATCCAACAGA 300 AACTAAAAAT GGAAGAGTAT GATGATGTTA ATTTGCTGAC TGCTGACTTC CAGCTTCTTT 360 TTAACAATGC AAAGTCCTAT TATAAGCCAG ATTCTCCTGA ATATAAAGCC GCTTGCAAAC 420 TCTGGGATTT GTACCTTCGA ACAAGAAATG AGTTTGTTCA GAAAGGAGAA GCAGATGACG 480 AAGATGATGA TGAAGATGGG CAAGACAATC AGGGCACAGT GACTGAAGGA TCTTCTCCAG 540 CTTACTTGAA GGAGATCCTG GAGCAGCTTC TTGAAGCCAT AGTTGTAGCT ACAAATCCAT 600 CAGGACGTCT CATTAGCGAA CTTTTTCAGA AACTGCCTTC TAAAGTGCAA TATCCAGATT 660 ATTATGCAAT AATTAAGGAG CCTATAGATC TCAAGACCAT TGCCCAGAGG ATACAGAATG 720 GAAGCTACAA AAGTATTCAT GCAATGGCCA AAGATATAGA TCTCCTCGCA AAAAATGCCA 780 AAACTTATAA TGAGCCTGGC TCTCAAGTAT TCAAGGATGC AAATTCAATT AAAAAAATAT 840 TTTATATGAA AAAGGCTGAA ATTGAACATC ATGAAATGGC TAAGTCAAGT CTTCGAATGA 900 GGACTCCATC CAACTTGGCT GCAGCCAGAC TGACAGGTCC TTCACACAGT AAAGGCAGCC 960 TTGGTGAAGA GAGAAATCCC ACTAGCAAGT ATTACCGTAA TAAAAGAGCA GTACAAGGAG 1020 GTCGTTTATC AGCAATTACA ATGGCACTTC AATATGGCTC AGAAAGTGAA GAAGATGCTG 1080 CTTTAGCTGC TGCACGCTAT GAAGAGGGAG AGTCAGAAGC AGAAAGCATC ACTTCCTTTA 1140 TGGATGTTTC AAATCCTTTT TATCAGCTTT ATGACACAGT TAGGAGTTGT CGGAATAACC 1200 AAGGGCAGCT AATAGCTGAA CCTTTTTACC ATTTGCCTTC AAAGAAAAAA TACCCTGATT 1260 ATTACCAGCA AATTAAAATG CCCATATCAC TACAACAGAT CCGAACAAAA CTGAAGAATC 1320 AAGAATATGA AACTTTAGAT CATTTGGAGT GTGATCTGAA TTTAATGTTT GAAAATGCCA 1380 AACGCTATAA TGTGCCCAAT TCAGCCATCT ACAAGCGAGT TCTAAAATTG CAGCAAGTTA 1440 TGCAGGCAAA GAAGAAAGAG CTTGCCAGGA GAGACGATAT CGAGGACGGA GACAGCATGA 1500 TCTCTTCAGC CACCTCTGAT ACTGGTAGTG CCAAAAGAAA AAGTAAAAAG AACATAAGAA 1560 AGCAGCGAAT GAAAATCTTA TTCAATGTTG TTCTTGAAGC TCGAGAGCCA GGTTCAGGCA 1620 GAAGACTTTG TGACCTATTT ATGGTTAAAC CATCCAAAAA GGACTATCCT GATTATTATA 1680 AAATCATCTT GGAGCCAATG GACTTGAAAA TAATTGAGCA TAACATCCGC AATGACAAAT 1740 ATGCTGGTGA AGAGGGAATG ATAGAAGACA TGAAGCTGAT GTTCCGGAAT GCCAGGCACT 1800 ATAATGAGGA GGGCTCCCAG GTTTATAATG ATGCACATAT CCTGGAGAAG TTACTCAAGG 1860 AGAAAAGGAA AGAGCTGGGC CCACTGCCTG ATGATGATGA CATGGCTTCT CCCAAACTCA 1920 AGCTGAGTAG GAAGAGTGGC ATTTCTCCTA AAAAATCAAA ATACATGACT CCAATGCAGC 1980 AGAAACTAAA TGAGGTCTAT GAAGCTGTAA AGAACTATAC TGATAAGAGG GGTCGCCGCC 2040 TCAGTGCCAT ATTTCTGAGG CTTCCCTCTA GATCTGAGTT GCCTGACTAC TATCTGACTA 2100 TTAAAAAGCC CATGGACATG GAAAAAATTC GAAGTCACAT GATGGCCAAC AAGTACCAAG 2160 ATATTGACTC TATGGTTGAG GACTTTGTCA TGATGTTTAA TAATGCCTGT ACATACAATG 2220 AGCCGGAGTC TTTGATCTAC AAAGATGCTC TTGTTCTACA CAAAGTCCTG CTTGAAACAC 2280 GCAGAGACCT GGAGGGAGAT GAGGACTCTC ATGTCCCAAA TGTGACTTTG CTGATTCAAG 2340 AGCTTATCCA CAATCTTTTT GTGTCAGTCA TGAGTCATCA GGATGATGAG GGAAGATGCT 2400 ACAGCGATTC TTTAGCAGAA ATTCCTGCTG TGGATCCCAA CTTTCCTAAC AAACCACCCC 2460 TTACATTTGA CATAATTAGG AAGAATGTTG AAAATAATCG CTACCGTCGG CTTGATTTAT 2520 TTCAAGAGCA TATGTTTGAA GTATTGGAAC GAGCAAGAAG GATGAATCGG ACAGATTCAG 2580 AAATATATGA AGATGCAGTA GAACTTCAGC AGTTTTTTAT TAAAATTCGT GATGAACTCT 2640 GCAAAAATGG AGAGATTCTT CTTTCACCGG CACTCAGCTA TACCACAAAA CATTTGCATA 2700 ATGATGTGGA GAAAGAGAGA AAGGAAAAAT TGCCAAAAGA AATAGAGGAA GATAAACTAA 2760 AACGAGAAGA AGAAAAAAGA GAAGCTGAAA AGAGTGAAGA TTCCTCTGGT GCTGCAGGCC 2820 TCTCAGGCTT ACATCGCACA TACAGCCAGG ACTGTAGCTT TAAAAACAGC ATGTACCATG 2880 TTGGAGATTA CGTCTATGTG GAACCTGCAG AGGCCAACCT ACAACCACAT ATCGTCTGTA 2940 TTGAAAGACT GTGGGAGGAT TCAGCTGGTG AAAAATGGTT GTATGGCTGT TGGTTTTACC 3000 GACCAAATGA AACATTCCAC CTGGCTACAC GAAAATTTCT AGAAAAAGAA GTTTTTAAGA 3060 GTGACTATTA CAACAAAGTT CCAGTTAGTA AAATTCTAGG CAAGTGTGTG GTCATGTTTG 3120 TCAAGGAATA CTTTAAGTTA TGCCCAGAAA ACTTCCGAGA TGAGGATGTT TTTGTCTGTG 3180 AATCACGGTA TTCTGCCAAA ACCAAATCTT TTAAGAAAAT TAAACTGTGG ACCATGCCCA 3240 TCAGCTCAGT CAGGTTTGTC CCTCGGGATG TGCCTCTGCC TGTGGTTCGC GTGGCCTCTG 3300 TATTTGCAAA TGCAGATAAA GGTGATGATG AGAAGAATAC AGACAACTCA GAGGACAGTC 3360 GAGCTGAAGA CAATTTTAAC TTGGAAAAGG AAAAAGAAGA TGTCCCTGTG GAAATGTCCA 3420 ATGGTGAACC AGGTTGCCAC TACTTTGAGC AGCTCCATTA CAATGACATG TGGCTGAAGG 3480 TTGGCGACTG TGTCTTCATC AAGTCCCATG GCCTGGTGCG TCCTCGTGTG GGCAGAATTG 3540 AAAAAGTATG GGTTCGAGAT GGAGCTGCAT ATTTTTATGG CCCCATCTTC ATTCACCCAG 3600 AAGAAACAGA GCATGAGCCC ACAAAAATGT TCTACAAAAA AGAAGTATTT CTGAGTAATC 3660 TGGAAGAAAC CTGCCCCATG ACATGTATTC TCGGAAAGTG TGCTGTGTTG TCATTCAAGG 3720 ACTTCCTCTC CTGCAGGCCA ACTGAAATAC CAGAAAATGA CATTCTGCTT TGTGAGAGCC 3780 GCTACAATGA GAGCGACAAG CAGATGAAGA AATTCAAAGG ATTGAAGAGG TTTTCACTCT 3840 CTGCTAAAGT GGTAGATGAT GAAATTTACT ACTTCAGAAA ACCAATTGTT CCTCAGAAGG 3900 AGCCATCACC TTTGCTGGAA AAGAAGATCC AGTTGCTAGA AGCTAAATTT GCCGAGTTAG 3960 AAGGTGGAGA TGATGATATT GAAGAGATGG GAGAAGAAGA TAGTGAGGTC ATTGAACCTC 4020 CTTCTCTACC TCAGCTTCAG ACCCCCCTGG CCAGTGAGCT GGACCTCATG CCCTACACAC 4080 CCCCACAGTC TACCCCAAAG TCTGCCAAAG GCAGTGCAAA GAAGGAAGGC TCCAAACGGA 4140 AAATCAACAT GAGTGGCTAC ATCCTGTTCA GCAGTGAGAT GAGGGCTGTG ATTAAGGCCC 4200 AACACCCAGA CTACTCTTTC GGGGAGCTCA GCCGCCTGGT GGGGACAGAA TGGAGAAATC 4260 TTGAGACAGC CAAGAAAGCA GAATATGAAG AGCGGGCAGC TAAAGTTGCT GAGCAGCAGG 4320 AGAGAGAGCG AGCAGCACAG CAACAGCAGC CGAGTGCTTC TCCCCGAGCA GGCACCCCTG 4380 TGGGGGCTCT CATGGGGGTG GTGCCACCAC CAACACCAAT GGGGATGCTC AATCAGCAGT 4440 TGACACCTGT TGCAGGCATG ATGGGTGGCT ATCCGCCAGG CCTTCCACCT TTGCAGGGCC 4500 CAGTTGATGG CCTTGTTAGC ATGGGCAGCA TGCAGCCACT TCACCCTGGG GGGCCTCCAC 4560 CCCACCATCT TCCGCCAGGT GTGCCTGGCC TCCCGGGCAT CCCACCACCG GGTGTGATGA 4620 ACCAAGGAGT GGCCCCTATG GTAGGGACTC CAGCACCAGG TGGAAGTCCA TATGGACAAC 4680 AGGTGGGAGT TTTGGGGCCT CCAGGGCAGC AGGCACCACC TCCATATCCC GGCCCACATC 4740 CAGCTGGACC CCCTGTCATA CAGCAGCCAA CAACACCCAT GTTTGTAGCT CCCCCACCAA 4800 AGACCCAGCG GCTTCTTCAC TCAGAGGCCT ACCTGAAATA CATTGAAGGA CTCAGTGCGG 4860 AGTCCAACAG CATTAGCAAG TGGGATCAGA CACTGGCAGC TCGAAGACGC GACGTCCATT 4920 TGTCGAAAGA ACAGGAGAGC CGCCTACCCT CTCACTGGCT GAAAAGCAAA GGGGCCCACA 4980 CCACCATGGC AGATGCCCTC TGGCGCCTTC GAGATTTGAT GCTCCGGGAC ACCCTCAACA 5040 TTCGCCAAGC ATACAACCTA GAAAATGTTT AATCACATCA TTACGTTTCT TTTATATAGA 5100 AGCATAAAGA GTTGTGGATC AGTAGCCATT TTAGTTACTG GGGGT
5146Nucleotide Fasta Sequence
>ENSP00000296302.7|Bromodomain|Homo sapiens CCATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCAGGCCCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGACTATAAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGAAATCAACCAGACTATTATGAAGTGGTTTCTCAGCCCATTGACTTGATGAAAATCCAACAGAAACTAAAAATGGAAGAGTATGATGATGTTAATTTGCTGACTGCTGACTTCCAGCTTCTTTTTAACAATGCAAAGTCCTATTATAAGCCAGATTCTCCTGAATATAAAGCCGCTTGCAAACTCTGGGATTTGTACCTTCGAACAAGAAATGAGTTTGTTCAGAAAGGAGAAGCAGATGACGAAGATGATGATGAAGATGGGCAAGACAATCAGGGCACAGTGACTGAAGGATCTTCTCCAGCTTACTTGAAGGAGATCCTGGAGCAGCTTCTTGAAGCCATAGTTGTAGCTACAAATCCATCAGGACGTCTCATTAGCGAACTTTTTCAGAAACTGCCTTCTAAAGTGCAATATCCAGATTATTATGCAATAATTAAGGAGCCTATAGATCTCAAGACCATTGCCCAGAGGATACAGAATGGAAGCTACAAAAGTATTCATGCAATGGCCAAAGATATAGATCTCCTCGCAAAAAATGCCAAAACTTATAATGAGCCTGGCTCTCAAGTATTCAAGGATGCAAATTCAATTAAAAAAATATTTTATATGAAAAAGGCTGAAATTGAACATCATGAAATGGCTAAGTCAAGTCTTCGAATGAGGACTCCATCCAACTTGGCTGCAGCCAGACTGACAGGTCCTTCACACAGTAAAGGCAGCCTTGGTGAAGAGAGAAATCCCACTAGCAAGTATTACCGTAATAAAAGAGCAGTACAAGGAGGTCGTTTATCAGCAATTACAATGGCACTTCAATATGGCTCAGAAAGTGAAGAAGATGCTGCTTTAGCTGCTGCACGCTATGAAGAGGGAGAGTCAGAAGCAGAAAGCATCACTTCCTTTATGGATGTTTCAAATCCTTTTTATCAGCTTTATGACACAGTTAGGAGTTGTCGGAATAACCAAGGGCAGCTAATAGCTGAACCTTTTTACCATTTGCCTTCAAAGAAAAAATACCCTGATTATTACCAGCAAATTAAAATGCCCATATCACTACAACAGATCCGAACAAAACTGAAGAATCAAGAATATGAAACTTTAGATCATTTGGAGTGTGATCTGAATTTAATGTTTGAAAATGCCAAACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTTCTAAAATTGCAGCAAGTTATGCAGGCAAAGAAGAAAGAGCTTGCCAGGAGAGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCCACCTCTGATACTGGTAGTGCCAAAAGAAAAAGTAAAAAGAACATAAGAAAGCAGCGAATGAAAATCTTATTCAATGTTGTTCTTGAAGCTCGAGAGCCAGGTTCAGGCAGAAGACTTTGTGACCTATTTATGGTTAAACCATCCAAAAAGGACTATCCTGATTATTATAAAATCATCTTGGAGCCAATGGACTTGAAAATAATTGAGCATAACATCCGCAATGACAAATATGCTGGTGAAGAGGGAATGATAGAAGACATGAAGCTGATGTTCCGGAATGCCAGGCACTATAATGAGGAGGGCTCCCAGGTTTATAATGATGCACATATCCTGGAGAAGTTACTCAAGGAGAAAAGGAAAGAGCTGGGCCCACTGCCTGATGATGATGACATGGCTTCTCCCAAACTCAAGCTGAGTAGGAAGAGTGGCATTTCTCCTAAAAAATCAAAATACATGACTCCAATGCAGCAGAAACTAAATGAGGTCTATGAAGCTGTAAAGAACTATACTGATAAGAGGGGTCGCCGCCTCAGTGCCATATTTCTGAGGCTTCCCTCTAGATCTGAGTTGCCTGACTACTATCTGACTATTAAAAAGCCCATGGACATGGAAAAAATTCGAAGTCACATGATGGCCAACAAGTACCAAGATATTGACTCTATGGTTGAGGACTTTGTCATGATGTTTAATAATGCCTGTACATACAATGAGCCGGAGTCTTTGATCTACAAAGATGCTCTTGTTCTACACAAAGTCCTGCTTGAAACACGCAGAGACCTGGAGGGAGATGAGGACTCTCATGTCCCAAATGTGACTTTGCTGATTCAAGAGCTTATCCACAATCTTTTTGTGTCAGTCATGAGTCATCAGGATGATGAGGGAAGATGCTACAGCGATTCTTTAGCAGAAATTCCTGCTGTGGATCCCAACTTTCCTAACAAACCACCCCTTACATTTGACATAATTAGGAAGAATGTTGAAAATAATCGCTACCGTCGGCTTGATTTATTTCAAGAGCATATGTTTGAAGTATTGGAACGAGCAAGAAGGATGAATCGGACAGATTCAGAAATATATGAAGATGCAGTAGAACTTCAGCAGTTTTTTATTAAAATTCGTGATGAACTCTGCAAAAATGGAGAGATTCTTCTTTCACCGGCACTCAGCTATACCACAAAACATTTGCATAATGATGTGGAGAAAGAGAGAAAGGAAAAATTGCCAAAAGAAATAGAGGAAGATAAACTAAAACGAGAAGAAGAAAAAAGAGAAGCTGAAAAGAGTGAAGATTCCTCTGGTGCTGCAGGCCTCTCAGGCTTACATCGCACATACAGCCAGGACTGTAGCTTTAAAAACAGCATGTACCATGTTGGAGATTACGTCTATGTGGAACCTGCAGAGGCCAACCTACAACCACATATCGTCTGTATTGAAAGACTGTGGGAGGATTCAGCTGGTGAAAAATGGTTGTATGGCTGTTGGTTTTACCGACCAAATGAAACATTCCACCTGGCTACACGAAAATTTCTAGAAAAAGAAGTTTTTAAGAGTGACTATTACAACAAAGTTCCAGTTAGTAAAATTCTAGGCAAGTGTGTGGTCATGTTTGTCAAGGAATACTTTAAGTTATGCCCAGAAAACTTCCGAGATGAGGATGTTTTTGTCTGTGAATCACGGTATTCTGCCAAAACCAAATCTTTTAAGAAAATTAAACTGTGGACCATGCCCATCAGCTCAGTCAGGTTTGTCCCTCGGGATGTGCCTCTGCCTGTGGTTCGCGTGGCCTCTGTATTTGCAAATGCAGATAAAGGTGATGATGAGAAGAATACAGACAACTCAGAGGACAGTCGAGCTGAAGACAATTTTAACTTGGAAAAGGAAAAAGAAGATGTCCCTGTGGAAATGTCCAATGGTGAACCAGGTTGCCACTACTTTGAGCAGCTCCATTACAATGACATGTGGCTGAAGGTTGGCGACTGTGTCTTCATCAAGTCCCATGGCCTGGTGCGTCCTCGTGTGGGCAGAATTGAAAAAGTATGGGTTCGAGATGGAGCTGCATATTTTTATGGCCCCATCTTCATTCACCCAGAAGAAACAGAGCATGAGCCCACAAAAATGTTCTACAAAAAAGAAGTATTTCTGAGTAATCTGGAAGAAACCTGCCCCATGACATGTATTCTCGGAAAGTGTGCTGTGTTGTCATTCAAGGACTTCCTCTCCTGCAGGCCAACTGAAATACCAGAAAATGACATTCTGCTTTGTGAGAGCCGCTACAATGAGAGCGACAAGCAGATGAAGAAATTCAAAGGATTGAAGAGGTTTTCACTCTCTGCTAAAGTGGTAGATGATGAAATTTACTACTTCAGAAAACCAATTGTTCCTCAGAAGGAGCCATCACCTTTGCTGGAAAAGAAGATCCAGTTGCTAGAAGCTAAATTTGCCGAGTTAGAAGGTGGAGATGATGATATTGAAGAGATGGGAGAAGAAGATAGTGAGGTCATTGAACCTCCTTCTCTACCTCAGCTTCAGACCCCCCTGGCCAGTGAGCTGGACCTCATGCCCTACACACCCCCACAGTCTACCCCAAAGTCTGCCAAAGGCAGTGCAAAGAAGGAAGGCTCCAAACGGAAAATCAACATGAGTGGCTACATCCTGTTCAGCAGTGAGATGAGGGCTGTGATTAAGGCCCAACACCCAGACTACTCTTTCGGGGAGCTCAGCCGCCTGGTGGGGACAGAATGGAGAAATCTTGAGACAGCCAAGAAAGCAGAATATGAAGAGCGGGCAGCTAAAGTTGCTGAGCAGCAGGAGAGAGAGCGAGCAGCACAGCAACAGCAGCCGAGTGCTTCTCCCCGAGCAGGCACCCCTGTGGGGGCTCTCATGGGGGTGGTGCCACCACCAACACCAATGGGGATGCTCAATCAGCAGTTGACACCTGTTGCAGGCATGATGGGTGGCTATCCGCCAGGCCTTCCACCTTTGCAGGGCCCAGTTGATGGCCTTGTTAGCATGGGCAGCATGCAGCCACTTCACCCTGGGGGGCCTCCACCCCACCATCTTCCGCCAGGTGTGCCTGGCCTCCCGGGCATCCCACCACCGGGTGTGATGAACCAAGGAGTGGCCCCTATGGTAGGGACTCCAGCACCAGGTGGAAGTCCATATGGACAACAGGTGGGAGTTTTGGGGCCTCCAGGGCAGCAGGCACCACCTCCATATCCCGGCCCACATCCAGCTGGACCCCCTGTCATACAGCAGCCAACAACACCCATGTTTGTAGCTCCCCCACCAAAGACCCAGCGGCTTCTTCACTCAGAGGCCTACCTGAAATACATTGAAGGACTCAGTGCGGAGTCCAACAGCATTAGCAAGTGGGATCAGACACTGGCAGCTCGAAGACGCGACGTCCATTTGTCGAAAGAACAGGAGAGCCGCCTACCCTCTCACTGGCTGAAAAGCAAAGGGGCCCACACCACCATGGCAGATGCCCTCTGGCGCCTTCGAGATTTGATGCTCCGGGACACCCTCAACATTCGCCAAGCATACAACCTAGAAAATGTTTAATCACATCATTACGTTTCTTTTATATAGAAGCATAAAGAGTTGTGGATCAGTAGCCATTTTAGTTACTGGGGGT
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Sequence Source |
Ensembl |
Keyword |
KW-0002--3D-structure KW-0007--Acetylation KW-0025--Alternative splicing KW-0103--Bromodomain KW-0156--Chromatin regulator KW-0181--Complete proteome KW-0238--DNA-binding KW-1017--Isopeptide bond KW-0539--Nucleus KW-0597--Phosphoprotein KW-0621--Polymorphism KW-1185--Reference proteome KW-0677--Repeat KW-0804--Transcription KW-0805--Transcription regulation KW-0043--Tumor suppressor KW-0832--Ubl conjugation --
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Interpro |
IPR001025--BAH_dom IPR001487--Bromodomain IPR018359--Bromodomain_CS IPR009071--HMG_box_dom
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PROSITE |
PS51038--BAH PS00633--BROMODOMAIN_1 PS50014--BROMODOMAIN_2 PS50118--HMG_BOX_2
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Pfam |
PF01426--BAH PF00439--Bromodomain PF00505--HMG_box
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Gene Ontology |
GO:0090544--C:BAF-type complex GO:0000228--C:nuclear chromosome GO:0005654--C:nucleoplasm GO:0003682--F:chromatin binding GO:0003677--F:DNA binding GO:0006338--P:chromatin remodeling GO:0007067--P:mitotic nuclear division GO:0008285--P:negative regulation of cell proliferation GO:0006355--P:regulation of transcription, DNA-templated GO:0006351--P:transcription, DNA-templated
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Orthology |
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Created Date |
25-Jun-2016 |