WERAM Information

Tag Content
WERAM ID WERAM-Art-0136
Ensembl Protein ID AT5G43990.4
Uniprot Accession Q9FNC7; SUVR2_ARATH; Q0WKU5; Q941L4
Genbank Protein ID NP_001078702.1; NP_001078703.1; NP_568631.1
Protein Name Probable inactive histone-lysine N-methyltransferase SUVR2
Genbank Nucleotide ID NM_001085233.1; NM_001085234.1; NM_123766.2
Gene Name SUVR2
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
AT5G43990 AT5G43990.4 AT5G43990.4
AT5G43990 AT5G43990.1 AT5G43990.1
AT5G43990 AT5G43990.2 AT5G43990.2
AT5G43990 AT5G43990.3 AT5G43990.3
AT5G43990 AT5G43990.5 AT5G43990.5
Details
Type Family Domain Substrates AA References (PMIDs)
HMT SUV39 SET H3K9 K 20703330
Status Reviewed
Classification
Type Family E-value Score Start End
HMT SUV39 1.40e-32 113.6 109 679
Organism Arabidopsis thaliana
NCBI Taxa ID 3702
Functional Description
(View)		 Probable inactive histone-lysine methyltransferase that acts as regulator of transctiptional gene silencing independently of histone H3K9 methylation. Contributes to transcriptional gene silencing at RNA-directed DNA methylation (RdDM) target loci but also at RdDM-independent target loci. Forms a complex with SUVR1 and associates with the SNF2-related chromatin-remodeling proteins CHR19, CHR27, and CHR28, thereby mediating nucleosome positioning and transcriptional silencing. Does not possess histone-lysine methyltransferase activity in vitro, and the conserved catalytic sites of SUVR2 are dispensable for its function in transcriptional gene silencing.
Domain Profile
  HMT SUV39
    SUV39.txt  79 s 79 
                   
  AT5G43990.4 109 L 109
                  1 PP
    SUV39.txt   2 rLqvfktenk.GwGvrclddiakgsFvciyaGeiltddeaekegleegdeyladldskesvenlkegyesdvplssdssntrqekdkeeseyiidakk 98 
                  +Lqvf t n  GwG+r+l++++kg+Fvc+ aGeilt  e  ++ ++++ +  + ld+ + +                     +  +++++ + ++ ++
  AT5G43990.4 551 KLQVFFTPNGrGWGLRTLEKLPKGAFVCELAGEILTIPELFQR-ISDRPTSPVILDAYWGS---------------------EDISGDDKALSLEGTH 626
                  8********99******************************99.78888888888887664.....................445788999******* PP
    SUV39.txt  99 egnvgrflnHsc.spNlfvqnvfvdthdlrfprvafFaskrikagtELtwdYg 150
                  +gn++rf+nH+c ++Nl+  +v  +t+d++++++afF++++i+a++ELtwdYg
  AT5G43990.4 627 YGNISRFINHRClDANLIEIPVHAETTDSHYYHLAFFTTREIDAMEELTWDYG 679
                  ****************************************************6 PP
Protein Sequence
(Fasta)		MAPNLHIKKA FMAMRAMGIE DARVKPVLKN LLALYEKNWE LIAEDNYRVL ADAIFDSHED 60
QAIQESEEKK ADEVKEDEGC AAEVDRGKKK LHESIEDDED VMAESDRPLK RLRRRGEGGS 120
ALASPSLGSP TLEGPSINDE ENAPILLPYH PVPIENDHDA GELILTKVEP ITNMPLSSIP 180
DSVDRGDSSM LEIDKSNGHV EEKAGETVST ADGTTNDISP TTVARFSDHK LAATIEEPPA 240
LELASSASGE VKINLSFAPA TGGSNPHLPS MEELRRAMEE KCLRSYKILD PNFSVLGFMN 300
DICSCYLDLA TNGRDSANQL PKNLPFVTTN IDALKKSAAR MAYTSQASND VVEICSNEHM 360
RDAENGAVGD SMALVVVPEC QLSADEWRLI SSVGDISLGK ETVEIPWVNE VNDKVPPVFH 420
YIAQSLVYQD AAVKFSLGNI RDDQCCSSCC GDCLAPSMAC RCATAFNGFA YTVDGLLQED 480
FLEQCISEAR DPRKQMLLYC KECPLEKAKK EVILEPCKGH LKRKAIKECW SKCGCMKNCG 540
NRVVQQGIHN KLQVFFTPNG RGWGLRTLEK LPKGAFVCEL AGEILTIPEL FQRISDRPTS 600
PVILDAYWGS EDISGDDKAL SLEGTHYGNI SRFINHRCLD ANLIEIPVHA ETTDSHYYHL 660
AFFTTREIDA MEELTWDYGV PFNQDVFPTS PFHCQCGSDF CRVRKQISKG KNVKKRA 717
Nucleotide Sequence
(Fasta)		AACAAAAAGT CACAGTCGAA CAAGATACTG AGAAAGAAAC GAAATTTCAC CTGGCACTGT 60
CCTCGCGTGT ACTCTCACGC GCCGACGTAA TACTCTGCCG TCGTCACCGA CATTGTCTCT 120
ACGCCGTTGT CATTTGCTTA TTACGGCCAA GATTCTTCAC TAAGTAAGTC AAAATCGTGG 180
AATCCTTTCT CTGTACCGAG CTCGCTTTAA ACCCTAACCC TCTCGTCTCT GTACTTAAAA 240
CGATGGCACC TAATCTGCAT ATCAAGAAAG CATTTATGGC TATGAGGGCT ATGGGAATAG 300
AGGATGCGCG AGTGAAGCCG GTCTTGAAAA ACCTTCTCGC CCTTTACGAG AAAAACTGGG 360
AGTTAATTGC TGAAGACAAT TACAGGGTTC TTGCTGATGC TATCTTCGAT AGCCATGAAG 420
ATCAGGCTAT TCAAGAAAGC GAAGAAAAGA AGGCAGACGA AGTTAAAGAG GATGAAGGCT 480
GTGCCGCAGA AGTTGACAGA GGAAAGAAAA AGCTCCATGA ATCTATCGAG GATGACGAAG 540
ATGTTATGGC TGAGTCTGAT CGCCCTTTAA AGAGGCTGCG ACGCAGAGGT GAAGGAGGCT 600
CTGCTTTGGC AAGCCCTAGC TTGGGCAGTC CGACTTTAGA GGGACCTTCA ATTAATGACG 660
AAGAAAATGC TCCGATCCTA TTGCCATATC ATCCTGTACC AATTGAAAAT GACCATGATG 720
CTGGTGAGCT CATTCTTACA AAAGTCGAGC CCATTACAAA TATGCCTCTC AGTTCTATTC 780
CTGATTCAGT AGATAGAGGG GACTCTTCCA TGCTTGAGAT AGACAAATCA AATGGACATG 840
TGGAAGAGAA GGCTGGTGAA ACAGTAAGTA CTGCTGATGG TACTACCAAT GACATTTCTC 900
CTACAACTGT TGCGAGATTT AGTGATCACA AGCTAGCTGC AACCATAGAA GAACCTCCAG 960
CACTTGAATT AGCTTCTTCT GCTTCAGGCG AGGTGAAGAT TAATCTTAGT TTTGCTCCTG 1020
CAACTGGAGG ATCAAATCCC CATTTACCTT CTATGGAGGA ACTACGAAGA GCAATGGAGG 1080
AGAAGTGTCT CCGATCATAC AAAATACTGG ACCCCAACTT TTCTGTGCTT GGTTTTATGA 1140
ACGACATCTG TAGCTGCTAC CTGGACCTGG CAACAAACGG GAGAGATTCA GCTAACCAAT 1200
TGCCAAAAAA CTTGCCGTTT GTCACAACGA ACATTGATGC ATTGAAGAAA TCTGCAGCAA 1260
GGATGGCTTA TACTTCTCAG GCCAGTAATG ATGTTGTTGA AATCTGCAGC AACGAACATA 1320
TGCGTGATGC TGAAAACGGT GCAGTTGGTG ATTCCATGGC TTTGGTAGTT GTTCCTGAAT 1380
GCCAACTTTC TGCAGATGAG TGGAGATTGA TAAGCAGCGT CGGGGACATC AGTCTAGGGA 1440
AAGAAACTGT TGAGATTCCC TGGGTGAATG AGGTCAACGA CAAAGTTCCT CCAGTTTTCC 1500
ATTACATAGC CCAAAGTCTT GTGTATCAAG ATGCTGCAGT GAAGTTTTCG CTTGGGAATA 1560
TCAGGGATGA CCAATGCTGC TCCTCTTGCT GTGGAGATTG CTTGGCTCCG TCAATGGCAT 1620
GCAGATGTGC AACTGCTTTT AATGGCTTTG CATACACAGT AGATGGCCTC CTACAGGAAG 1680
ATTTTCTGGA ACAGTGTATC TCTGAGGCCC GTGATCCGCG GAAACAAATG TTACTGTATT 1740
GCAAAGAATG TCCTTTAGAG AAAGCCAAAA AAGAAGTAAT CCTGGAACCG TGCAAAGGGC 1800
ATCTAAAGAG AAAGGCCATT AAAGAATGTT GGAGCAAGTG TGGCTGCATG AAGAATTGTG 1860
GCAACCGAGT TGTCCAACAG GGCATTCACA ACAAGCTGCA GGTGTTTTTC ACGCCCAATG 1920
GGAGAGGCTG GGGACTCAGA ACTCTAGAAA AACTGCCTAA AGGAGCATTT GTCTGTGAGC 1980
TTGCTGGAGA GATATTGACC ATTCCAGAGT TGTTCCAACG CATCTCTGAC AGGCCTACTT 2040
CTCCAGTAAT ATTGGATGCG TACTGGGGTT CTGAAGACAT TTCAGGGGAT GACAAAGCAC 2100
TTTCTCTTGA AGGAACGCAC TATGGAAATA TTTCCAGGTT CATCAATCAC AGATGCTTAG 2160
ATGCAAATTT GATTGAGATC CCAGTTCATG CGGAGACTAC TGATTCACAC TACTATCATC 2220
TTGCATTCTT CACAACAAGA GAGATCGATG CTATGGAGGA ACTTACCTGG GATTATGGTG 2280
TCCCATTCAA CCAAGATGTG TTTCCCACGA GTCCGTTCCA TTGTCAATGT GGTAGCGACT 2340
TCTGCCGAGT CAGGAAGCAG ATTAGCAAAG GCAAGAATGT GAAGAAGCGA GCATGAGAGA 2400
GAGCTTTACA TTGGTAGGTT TTGAAGATAT GTGGTGGGCG CAAACTCCTT TTTGTTGTGA 2460
ATGAATTGGC AAAAAAATTC CAATCGAAAA ACGCTTTTTG TAAAAAATTC CGACAATGCA 2520
TATAAGCAAA GTCGCGGTCC ATAAAATAGG TAGGTAGCTA TCAGGATGAA ACTATAATCC 2580
TTAGAAACTG ATTCACTTTT GTGATATCAA AAACTCGTGT GAATATCTTA ATTTTGGTTC 2640
TAACGGCTAT GGCTTTTGGT TATGACTT 2669
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0156--Chromatin regulator
KW-0158--Chromosome
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0943--RNA-mediated gene silencing
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
--
Interpro

IPR007728--Pre-SET_dom
IPR001214--SET_dom
IPR025776--SUVR4/1/2
IPR018848--WIYLD_domain
PROSITE

PS51580--SAM_MT43_3
PS50280--SET
Pfam

PF05033--Pre-SET
PF00856--SET
PF10440--WIYLD
Gene Ontology

GO:0005694--C:chromosome
GO:0005634--C:nucleus
GO:0018024--F:histone-lysine N-methyltransferase activity
GO:0008270--F:zinc ion binding
GO:0031047--P:gene silencing by RNA
Orthology
WERAM ID Ensembl Protein ID Species Identity E-value Score
WERAM-Arl-0116 fgenesh2_kg.8__ 416__ AT5G43990.4 Arabidopsis lyrata 88 0.0 1214
WERAM-Brr-0164 Bra033710.1-P Brassica rapa 62 0.0 885
WERAM-Bro-0126 Bo7g066910.1 Brassica oleracea 61 0.0 874
WERAM-Pot-0034 POPTR_0002s25920.1 Populus trichocarpa 48 2e-148 523
WERAM-Thc-0012 EOX94337 Theobroma cacao 49 2e-145 513
WERAM-Mua-0037 GSMUA_Achr1P20340_001 Musa acuminata 41 2e-132 470
WERAM-Viv-0044 VIT_07s0005g04190.t01 Vitis vinifera 45 1e-129 461
WERAM-Met-0022 KEH42476 Medicago truncatula 39 6e-129 459
WERAM-Prp-0034 EMJ00908 Prunus persica 43 7e-128 455
WERAM-Glm-0159 GLYMA13G18851.1 Glycine max 43 3e-125 446
WERAM-Amt-0047 ERN15944 Amborella trichopoda 45 3e-122 437
WERAM-Orni-0102 ONIVA09G12590.1 Oryza nivara 38 4e-115 413
WERAM-Ors-0024 OS02T0621100-01 Oryza sativa 37 4e-115 412
WERAM-Orr-0025 ORUFI02G25800.1 Oryza rufipogon 38 6e-115 412
WERAM-Brd-0035 BRADI1G64870.1 Brachypodium distachyon 38 5e-114 409
WERAM-Lep-0050 LPERR04G26410.1 Leersia perrieri 45 5e-112 402
WERAM-Orm-0028 OMERI02G23960.1 Oryza meridionalis 37 4e-110 396
WERAM-Sob-0108 Sb07g023480.1 Sorghum bicolor 37 5e-110 396
WERAM-Orb-0049 OBART04G30870.1 Oryza barthii 45 1e-108 391
WERAM-Ori-0027 BGIOSGA008642-PA Oryza indica 44 1e-108 391
WERAM-Orgl-0048 OGLUM04G30830.1 Oryza glumaepatula 45 2e-108 390
WERAM-Org-0027 ORGLA02G0211700.1 Oryza glaberrima 44 2e-108 390
WERAM-Orl-0074 KN539582.1_FGP009 Oryza longistaminata 45 3e-108 390
WERAM-Orbr-0059 OB04G37970.1 Oryza brachyantha 44 4e-108 390
WERAM-Sol-0086 Solyc06g083760.2.1 Solanum lycopersicum 56 9e-107 385
WERAM-Sei-0074 Si019326m Setaria italica 43 2e-106 384
WERAM-Zem-0112 GRMZM2G318803_P01 Zea mays 37 2e-106 384
WERAM-Sot-0059 PGSC0003DMT400051920 Solanum tuberosum 57 2e-106 384
WERAM-Aet-0081 EMT14309 Aegilops tauschii 43 9e-104 375
WERAM-Tra-0082 Traes_2DL_651A6EFC9.1 Triticum aestivum 43 6e-103 372
WERAM-Tru-0094 TRIUR3_33156-P1 Triticum urartu 44 4e-101 366
WERAM-Hov-0084 MLOC_63852.1 Hordeum vulgare 45 9e-101 365
WERAM-Orp-0047 OPUNC04G28530.1 Oryza punctata 44 1e-98 358
WERAM-Php-0112 PP1S523_9V6.1 Physcomitrella patens 48 5e-78 289
WERAM-Sem-0006 EFJ20940 Selaginella moellendorffii 46 6e-71 266
WERAM-Pof-0219 ENSPFOP00000017761.1 Poecilia formosa 31 9e-32 136
WERAM-Cis-0009 ENSCSAVP00000000984.1 Ciona savignyi 33 9e-32 136
WERAM-Cii-0064 ENSCINP00000028043.2 Ciona intestinalis 34 1e-31 135
WERAM-Xim-0080 ENSXMAP00000007374.1 Xiphophorus maculatus 31 2e-31 134
WERAM-Sah-0144 ENSSHAP00000015022.1 Sarcophilus harrisii 32 5e-30 130
WERAM-Mod-0151 ENSMODP00000021357.3 Monodelphis domestica 32 6e-30 130
WERAM-Orla-0146 ENSORLP00000017297.1 Oryzias latipes 32 9e-30 129
WERAM-Dar-0154 ENSDARP00000089135.3 Danio rerio 30 2e-29 128
WERAM-Myl-0132 ENSMLUP00000010608.2 Myotis lucifugus 32 2e-29 128
WERAM-Orn-0153 ENSONIP00000016204.1 Oreochromis niloticus 31 3e-29 127
WERAM-Ten-0062 ENSTNIP00000007887.1 Tetraodon nigroviridis 31 3e-29 127
WERAM-Tar-0120 ENSTRUP00000025101.1 Takifugu rubripes 31 3e-29 127
WERAM-Anc-0114 ENSACAP00000010952.3 Anolis carolinensis 30 7e-29 126
WERAM-Mum-0143 ENSMUSP00000119057.2 Mus musculus 31 8e-29 126
WERAM-Cap-0085 ENSCPOP00000006136.2 Cavia porcellus 31 9e-29 126
WERAM-Loa-0059 ENSLAFP00000004284.2 Loxodonta africana 39 9e-29 126
WERAM-Caf-0160 ENSCAFP00000022855.3 Canis familiaris 39 9e-29 126
WERAM-Bot-0055 ENSBTAP00000006178.3 Bos taurus 39 9e-29 126
WERAM-Mam-0182 ENSMMUP00000012343.2 Macaca mulatta 39 1e-28 126
WERAM-Hos-0062 ENSP00000365877.3 Homo sapiens 39 1e-28 126
WERAM-Chs-0160 ENSCSAP00000009389.1 Chlorocebus sabaeus 39 1e-28 126
WERAM-Tut-0161 ENSTTRP00000013419.1 Tursiops truncatus 40 1e-28 126
WERAM-Ova-0026 ENSOARP00000003659.1 Ovis aries 40 1e-28 126
WERAM-Mup-0156 ENSMPUP00000013545.1 Mustela putorius furo 39 1e-28 126
WERAM-Ict-0133 ENSSTOP00000013735.2 Ictidomys tridecemlineatus 39 1e-28 125
WERAM-Otg-0219 ENSOGAP00000017526.1 Otolemur garnettii 39 1e-28 125
WERAM-Dan-0124 ENSDNOP00000016943.2 Dasypus novemcinctus 39 1e-28 125
WERAM-Nol-0077 ENSNLEP00000009588.2 Nomascus leucogenys 39 1e-28 125
WERAM-Soa-0126 ENSSARP00000012347.1 Sorex araneus 38 1e-28 125
WERAM-Dio-0152 ENSDORP00000013968.1 Dipodomys ordii 31 1e-28 125
WERAM-Ran-0046 ENSRNOP00000063511.3 Rattus norvegicus 31 2e-28 125
WERAM-Gam-0093 ENSGMOP00000009644.1 Gadus morhua 37 2e-28 125
WERAM-Fec-0013 ENSFCAP00000001127.3 Felis catus 31 2e-28 125
WERAM-Pes-0039 ENSPSIP00000006137.1 Pelodiscus sinensis 31 3e-28 124
WERAM-Poa-0147 ENSPPYP00000018412.2 Pongo abelii 40 3e-28 124
WERAM-Sus-0015 ENSSSCP00000001517.1 Sus scrofa 40 3e-28 124
WERAM-Orc-0065 ENSOCUP00000006046.3 Oryctolagus cuniculus 40 3e-28 124
WERAM-Pat-0148 ENSPTRP00000050361.3 Pan troglodytes 40 3e-28 124
WERAM-Aim-0146 ENSAMEP00000013634.1 Ailuropoda melanoleuca 40 3e-28 124
WERAM-Mim-0034 ENSMICP00000003271.1 Microcebus murinus 40 4e-28 124
WERAM-Eqc-0010 ENSECAP00000003787.1 Equus caballus 40 4e-28 124
WERAM-Ptv-0045 ENSPVAP00000004855.1 Pteropus vampyrus 40 4e-28 124
WERAM-Caj-0240 ENSCJAP00000004503.2 Callithrix jacchus 40 4e-28 124
WERAM-Ocp-0041 ENSOPRP00000003534.2 Ochotona princeps 40 4e-28 124
WERAM-Paa-0026 ENSPANP00000006203.1 Papio anubis 38 4e-28 124
WERAM-Gog-0222 ENSGGOP00000023434.1 Gorilla gorilla 38 4e-28 124
WERAM-Lac-0126 ENSLACP00000014864.1 Latimeria chalumnae 31 4e-28 124
WERAM-Fia-0077 ENSFALP00000005785.1 Ficedula albicollis 31 4e-28 124
WERAM-Gaga-0086 ENSGALP00000013792.4 Gallus gallus 31 4e-28 124
WERAM-Gaa-0188 ENSGACP00000023866.1 Gasterosteus aculeatus 30 5e-28 124
WERAM-Tag-0044 ENSTGUP00000002934.1 Taeniopygia guttata 31 5e-28 123
WERAM-Asm-0001 ENSAMXP00000000184.1 Astyanax mexicanus 38 6e-28 123
WERAM-Meg-0025 ENSMGAP00000001979.2 Meleagris gallopavo 31 7e-28 123
WERAM-Xet-0075 ENSXETP00000023873.2 Xenopus tropicalis 31 1e-27 122
WERAM-Leo-0011 ENSLOCP00000001939.1 Lepisosteus oculatus 30 1e-27 122
WERAM-Tas-0041 ENSTSYP00000004126.1 Tarsius syrichta 35 2e-26 118
Created Date 25-Jun-2016