WERAM Information


Tag Content
WERAM ID WERAM-Art-0108
Ensembl Protein ID AT4G29510.1
Uniprot Accession Q9SU94; ANM11_ARATH; O81813; Q8VZP0
Genbank Protein ID NP_194680.1
Protein Name Protein arginine N-methyltransferase 1.1
Genbank Nucleotide ID NM_119096.2
Gene Name PRMT11;ANM11
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
AT4G29510 AT4G29510.1 AT4G29510.1
Details
Type Family Domain Substrates AA References (PMIDs)
HMT PRMT PRMT-type H4R3 R 17666011
Status Reviewed
Classification
Type Family E-value Score Start End
HMT PRMT 1.50e-129 432.5 70 370
Organism Arabidopsis thaliana
NCBI Taxa ID 3702
Functional Description
(View)
Methylates (mono and asymmetric dimethylation) the guanidino nitrogens of arginyl residues present in a glycine and arginine-rich domain. Type I arginine methyltransferase active on both histones and non-histone proteins. Required for leaves and flowers development. Mediates the methylation of MBD7 and MED36A.
Domain Profile
  HMT PRMT

     PRMT.txt   2 qqylqslselLesgvyeemlkDevrtdaYreailknktllkdkvvldvGaGtGiLslfaakagarkvyavekspmakvarkvvkvnglkdrvtvikgk 99 
++y++s+s++ g++eemlkD vrt++Y+++i++nk+l+kdk+vldvGaGtGiLslf+akaga++vyave+s+ma++a+++vk+ng++d++tv+kgk
AT4G29510.1 70 DYYFDSYSHF---GIHEEMLKDVVRTKTYQNVIYQNKFLIKDKIVLDVGAGTGILSLFCAKAGAAHVYAVECSQMADMAKEIVKANGFSDVITVLKGK 164
89********...************************************************************************************* PP
PRMT.txt 100 veelelpkekvDiivSEllgsfllnEsllpsvlhardkfLkddglslPdkatlyvapiedtklykeekaefwksvygvdlsclekaaikeqfesplVd 197
+ee+elp++kvD+i+SE++g+fll+E++l+svl+ardk+L+++g++lPdka+l++++ied++ yke+k+efw+svyg+d+sc++k+a++e plVd
AT4G29510.1 165 IEEIELPTPKVDVIISEWMGYFLLFENMLDSVLYARDKWLVEGGVVLPDKASLHLTAIEDSE-YKEDKIEFWNSVYGFDMSCIKKKAMME----PLVD 257
**************************************************************.**************************9....9*** PP
PRMT.txt 198 tldkekllsepkkiftfdiskakesdeerelslelevkrnaslhglaayFdvqft.sektvvlStaPetkspathWkqavlyledpltvkegekis.. 292
t+d++++++++++++t+disk++++d++++++++l+++rn+++h+l+ayFdv+ft ++k +++St P ks+athWkq+vlyled+lt++ege+i+
AT4G29510.1 258 TVDQNQIVTDSRLLKTMDISKMSSGDASFTAPFKLVAQRNDYIHALVAYFDVSFTmCHKLLGFSTGP--KSRATHWKQTVLYLEDVLTICEGETITgt 353
*******************************************************************..***************************** PP
PRMT.txt 293 illlarkknsrdvdyel 309
+++ ++kkn+rd+d++l
AT4G29510.1 354 MSVSPNKKNPRDIDIKL 370
***************98 PP

Protein Sequence
(Fasta)
MTKNSNHDEN EFISFEPNQN TKIRFEDADE DEVAEGSGVA GEETPQDESM FDAGESADTA 60
EVTDDTTSAD YYFDSYSHFG IHEEMLKDVV RTKTYQNVIY QNKFLIKDKI VLDVGAGTGI 120
LSLFCAKAGA AHVYAVECSQ MADMAKEIVK ANGFSDVITV LKGKIEEIEL PTPKVDVIIS 180
EWMGYFLLFE NMLDSVLYAR DKWLVEGGVV LPDKASLHLT AIEDSEYKED KIEFWNSVYG 240
FDMSCIKKKA MMEPLVDTVD QNQIVTDSRL LKTMDISKMS SGDASFTAPF KLVAQRNDYI 300
HALVAYFDVS FTMCHKLLGF STGPKSRATH WKQTVLYLED VLTICEGETI TGTMSVSPNK 360
KNPRDIDIKL SYSLNGQHCK ISRTQHYKMR
Nucleotide Sequence
(Fasta)
AAAAACTTCA AATTAAAAGC TTCGTGTCTT CATAAAACCC TAATCTCGCG ACTTCGTCTC 60
TATCCCCAAA AACCCTTTCC TCTCTTCCTT CTTGTGTGAG ACCGAGAAAA AAAGATGACT 120
AAGAACAGTA ACCACGACGA GAATGAGTTC ATCAGCTTTG AACCAAATCA GAACACGAAG 180
ATACGCTTTG AAGATGCTGA TGAAGACGAA GTTGCTGAAG GGTCTGGTGT TGCCGGCGAG 240
GAAACTCCCC AAGATGAGTC CATGTTCGAC GCCGGAGAGA GCGCCGACAC CGCTGAAGTA 300
ACTGATGATA CCACCAGTGC CGATTACTAC TTCGATTCTT ACTCTCACTT TGGAATCCAT 360
GAAGAGATGT TGAAGGATGT TGTGAGAACA AAGACTTATC AGAATGTTAT TTATCAGAAC 420
AAGTTTCTTA TCAAGGACAA AATTGTTCTT GATGTTGGAG CTGGAACCGG AATTTTGTCT 480
CTGTTCTGTG CCAAGGCAGG AGCTGCTCAT GTCTACGCTG TTGAGTGTTC TCAAATGGCT 540
GACATGGCAA AGGAGATTGT TAAAGCTAAT GGATTTTCTG ATGTTATTAC GGTATTGAAA 600
GGGAAGATTG AGGAGATAGA GCTTCCCACT CCTAAAGTGG ATGTGATTAT ATCGGAATGG 660
ATGGGTTACT TTTTGTTGTT TGAAAATATG TTGGACAGTG TCTTGTATGC TCGTGATAAA 720
TGGCTTGTTG AAGGTGGAGT TGTGCTACCA GACAAAGCCT CTCTGCATCT TACAGCCATA 780
GAGGATTCAG AGTACAAAGA AGACAAAATC GAATTTTGGA ACAGTGTGTA TGGTTTTGAC 840
ATGTCATGTA TTAAGAAAAA AGCTATGATG GAACCACTTG TTGACACAGT CGACCAAAAC 900
CAAATCGTCA CCGATAGTAG GCTTCTAAAG ACGATGGATA TCTCAAAGAT GTCCTCTGGT 960
GATGCTTCCT TCACAGCTCC CTTTAAGCTT GTTGCACAAC GCAATGACTA CATCCACGCC 1020
CTTGTAGCCT ACTTTGATGT ATCGTTTACC ATGTGCCACA AGCTGCTGGG CTTCTCAACA 1080
GGACCGAAAT CCCGAGCTAC ACACTGGAAA CAAACAGTTC TGTATCTAGA AGATGTGTTA 1140
ACCATATGTG AGGGTGAGAC AATCACTGGA ACTATGTCCG TTTCTCCTAA CAAGAAGAAT 1200
CCTCGAGACA TTGACATAAA GCTAAGCTAT TCTTTGAATG GCCAGCATTG CAAGATCTCA 1260
AGGACCCAAC ACTACAAAAT GCGTTAAAGT TCTCTCATAA GAAGCAGAAC TTCAGAAGAT 1320
ACAATTCTCA TATTGTGATT TAGTTTTTAT ATTTCTTTTT CTCCAGATTA CAACTTTCCA 1380
TTTGCTTCAC ATTGCAACAT TTGCTTCATC TCAAGTTAAA TTAATGATTT TGCTCTAAAC 1440
CATCTCGTGT ATGTTCCTTG TTGATCACAA AACTGATGTC TGTCAACACT TTTCAATATT 1500
CTCTCCAAAA GATTATAGAA ACTAAAGGAA ATCTAC 1537
Sequence Source Ensembl
Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0808--Transferase
--

Interpro

IPR025799--Arg_MeTrfase
IPR029063--SAM-dependent_MTases

PROSITE

PS51678--SAM_MT_PRMT

Pfam
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0008469--F:histone-arginine N-methyltransferase activity
GO:0016274--F:protein-arginine N-methyltransferase activity
GO:0035242--F:protein-arginine omega-N asymmetric methyltransferase activity
GO:0034969--P:histone arginine methylation
GO:0019919--P:peptidyl-arginine methylation, to asymmetrical-dimethyl arginine
GO:0035246--P:peptidyl-arginine N-methylation
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated

Orthology
WERAM ID Ensembl Protein ID Species Identity E-value Score
WERAM-Arl-0104 fgenesh2_kg.7__ 1240__ AT4G29510.1 Arabidopsis lyrata 98 0.0 742
WERAM-Bro-0008 Bo1g016300.1 Brassica oleracea 93 0.0 706
WERAM-Brr-0058 Bra011118.1-P Brassica rapa 92 0.0 705
WERAM-Orp-0094 OPUNC09G06130.1 Oryza punctata 86 2e-176 615
WERAM-Orbr-0106 OB09G14680.1 Oryza brachyantha 85 4e-176 614
WERAM-Tra-0192 Traes_5BL_3A2322B2E.2 Triticum aestivum 79 1e-175 613
WERAM-Glm-0002 GLYMA01G00690.1 Glycine max 78 2e-175 612
WERAM-Prp-0065 EMJ03380 Prunus persica 78 2e-175 612
WERAM-Ors-0089 OS09T0359800-01 Oryza sativa 85 5e-175 611
WERAM-Ori-0105 BGIOSGA029907-PA Oryza indica 85 5e-175 611
WERAM-Orr-0104 ORUFI09G07750.1 Oryza rufipogon 85 8e-175 610
WERAM-Orm-0091 OMERI09G05740.1 Oryza meridionalis 85 8e-175 610
WERAM-Orni-0099 ONIVA09G06350.1 Oryza nivara 85 8e-175 610
WERAM-Thc-0106 EOY30515 Theobroma cacao 76 2e-174 608
WERAM-Orgl-0097 OGLUM09G07670.1 Oryza glumaepatula 85 2e-174 608
WERAM-Sol-0140 Solyc12g008760.1.1 Solanum lycopersicum 73 3e-174 608
WERAM-Sob-0026 Sb02g022770.1 Sorghum bicolor 84 4e-174 608
WERAM-Zem-0005 GRMZM2G003038_P01 Zea mays 81 7e-174 607
WERAM-Sei-0116 Si030136m Setaria italica 85 1e-173 606
WERAM-Brd-0106 BRADI4G28570.1 Brachypodium distachyon 85 1e-173 606
WERAM-Lep-0097 LPERR09G04910.1 Leersia perrieri 83 4e-172 601
WERAM-Aet-0089 EMT02681 Aegilops tauschii 76 8e-172 600
WERAM-Viv-0069 VIT_11s0016g02530.t01 Vitis vinifera 83 2e-171 599
WERAM-Tru-0021 TRIUR3_09095-P1 Triticum urartu 80 4e-171 598
WERAM-Pot-0165 POPTR_0018s06940.1 Populus trichocarpa 77 1e-170 596
WERAM-Mua-0092 GSMUA_Achr6P22570_001 Musa acuminata 82 3e-170 595
WERAM-Met-0146 AES77098 Medicago truncatula 77 3e-169 592
WERAM-Orb-0101 OBART09G07280.1 Oryza barthii 83 2e-167 585
WERAM-Sot-0025 PGSC0003DMT400021726 Solanum tuberosum 73 2e-163 572
WERAM-Hov-0038 MLOC_38219.1 Hordeum vulgare 85 2e-161 566
WERAM-Sem-0139 EFJ32427 Selaginella moellendorffii 78 3e-160 561
WERAM-Php-0086 PP1S34_403V6.1 Physcomitrella patens 76 9e-160 560
WERAM-Amt-0040 ERN15472 Amborella trichopoda 83 2e-158 555
WERAM-Chr-0036 EDP05986 Chlamydomonas reinhardtii 61 2e-128 456
WERAM-Xim-0130 ENSXMAP00000010881.1 Xiphophorus maculatus 58 6e-120 427
WERAM-Pof-0107 ENSPFOP00000009428.2 Poecilia formosa 58 6e-120 427
WERAM-Pem-0065 ENSPMAP00000007105.1 Petromyzon marinus 59 3e-119 425
WERAM-Orn-0089 ENSONIP00000009834.1 Oreochromis niloticus 57 7e-119 424
WERAM-Ten-0101 ENSTNIP00000011632.1 Tetraodon nigroviridis 60 8e-119 424
WERAM-Orla-0186 ENSORLP00000021497.1 Oryzias latipes 58 8e-119 424
WERAM-Leo-0175 ENSLOCP00000020823.1 Lepisosteus oculatus 59 3e-118 422
WERAM-Gam-0045 ENSGMOP00000004857.1 Gadus morhua 57 4e-118 422
WERAM-Dar-0103 ENSDARP00000059488.6 Danio rerio 59 5e-118 421
WERAM-Tar-0087 ENSTRUP00000016696.1 Takifugu rubripes 59 5e-118 421
WERAM-Loa-0165 ENSLAFP00000015131.3 Loxodonta africana 57 8e-118 421
WERAM-Ict-0181 ENSSTOP00000019319.1 Ictidomys tridecemlineatus 57 1e-117 420
WERAM-Hos-0111 ENSP00000406162.2 Homo sapiens 57 1e-117 420
WERAM-Fec-0064 ENSFCAP00000005652.3 Felis catus 57 1e-117 420
WERAM-Caf-0040 ENSCAFP00000005344.3 Canis familiaris 57 1e-117 420
WERAM-Tut-0070 ENSTTRP00000005225.1 Tursiops truncatus 57 1e-117 420
WERAM-Sah-0075 ENSSHAP00000008934.1 Sarcophilus harrisii 58 1e-117 420
WERAM-Xet-0021 ENSXETP00000006288.3 Xenopus tropicalis 59 1e-117 420
WERAM-Asm-0107 ENSAMXP00000010647.1 Astyanax mexicanus 59 1e-117 420
WERAM-Dio-0153 ENSDORP00000014041.1 Dipodomys ordii 57 2e-117 419
WERAM-Eqc-0106 ENSECAP00000012211.1 Equus caballus 58 2e-117 419
WERAM-Sus-0010 ENSSSCP00000000777.2 Sus scrofa 58 2e-117 419
WERAM-Otg-0123 ENSOGAP00000010681.2 Otolemur garnettii 59 3e-117 419
WERAM-Gog-0003 ENSGGOP00000000495.2 Gorilla gorilla 59 3e-117 419
WERAM-Cap-0171 ENSCPOP00000019509.1 Cavia porcellus 59 3e-117 419
WERAM-Bot-0068 ENSBTAP00000008734.4 Bos taurus 59 3e-117 419
WERAM-Myl-0186 ENSMLUP00000015587.2 Myotis lucifugus 59 3e-117 419
WERAM-Gaga-0125 ENSGALP00000021646.3 Gallus gallus 58 4e-117 418
WERAM-Aim-0060 ENSAMEP00000005316.1 Ailuropoda melanoleuca 58 5e-117 418
WERAM-Mum-0296 ENSMUSP00000103474.3 Mus musculus 56 5e-117 418
WERAM-Ova-0115 ENSOARP00000011324.1 Ovis aries 58 5e-117 418
WERAM-Ran-0233 ENSRNOP00000071703.1 Rattus norvegicus 58 6e-117 418
WERAM-Anp-0070 ENSAPLP00000008515.1 Anas platyrhynchos 58 6e-117 418
WERAM-Mod-0117 ENSMODP00000017005.2 Monodelphis domestica 59 8e-117 417
WERAM-Pat-0037 ENSPTRP00000007772.4 Pan troglodytes 58 9e-117 417
WERAM-Chs-0139 ENSCSAP00000007430.1 Chlorocebus sabaeus 58 9e-117 417
WERAM-Paa-0117 ENSPANP00000011666.1 Papio anubis 58 9e-117 417
WERAM-Dan-0129 ENSDNOP00000026224.1 Dasypus novemcinctus 58 9e-117 417
WERAM-Caj-0200 ENSCJAP00000035087.2 Callithrix jacchus 58 9e-117 417
WERAM-Mup-0100 ENSMPUP00000009285.1 Mustela putorius furo 58 9e-117 417
WERAM-Gaa-0048 ENSGACP00000006490.1 Gasterosteus aculeatus 56 1e-116 417
WERAM-Ocp-0019 ENSOPRP00000001852.1 Ochotona princeps 58 1e-116 417
WERAM-Tag-0160 ENSTGUP00000013567.1 Taeniopygia guttata 58 1e-116 417
WERAM-Anc-0044 ENSACAP00000004792.3 Anolis carolinensis 55 1e-116 416
WERAM-Poa-0039 ENSPPYP00000004741.2 Pongo abelii 58 2e-116 416
WERAM-Ere-0019 ENSEEUP00000001289.1 Erinaceus europaeus 58 2e-116 416
WERAM-Orc-0046 ENSOCUP00000004606.2 Oryctolagus cuniculus 57 2e-116 416
WERAM-Miv-0028 MVLG_04058T0 Microbotryum violaceum 58 8e-116 414
WERAM-Ora-0054 ENSOANP00000008251.2 Ornithorhynchus anatinus 58 8e-116 414
WERAM-Fia-0065 ENSFALP00000004971.1 Ficedula albicollis 58 3e-115 412
WERAM-Drm-0065 FBpp0081780 Drosophila melanogaster 55 3e-111 399
WERAM-Cis-0061 ENSCSAVP00000013969.1 Ciona savignyi 55 1e-110 397
WERAM-Mam-0022 ENSMMUP00000004045.2 Macaca mulatta 61 2e-110 396
WERAM-Mim-0117 ENSMICP00000011732.1 Microcebus murinus 59 5e-108 388
WERAM-Mae-0039 ENSMEUP00000003714.1 Macropus eugenii 57 4e-107 385
WERAM-Lac-0166 ENSLACP00000019867.1 Latimeria chalumnae 59 5e-102 368
WERAM-Nol-0137 ENSNLEP00000015037.1 Nomascus leucogenys 39 9e-51 198
Created Date 25-Jun-2016