| Tag |
Content |
| WERAM ID |
WERAM-Art-0051 |
| Ensembl Protein ID |
AT2G34880.1 |
| Uniprot Accession |
O64752; JMJ15_ARATH
|
| Genbank Protein ID |
NP_181034.1
|
| Protein Name |
Lysine-specific demethylase JMJ15 |
| Genbank Nucleotide ID |
NM_129041.1
|
| Gene Name |
JMJ15;JARID1family |
| Ensembl Information |
|
| Details |
| Type |
Family |
Domain |
Substrates |
AA |
References (PMIDs) |
| HDM |
JARID |
Jmjc |
H3K4me3 |
K |
22555401
|
|
| Status |
Reviewed |
| Classification |
| Type |
Family |
E-value |
Score |
Start |
End |
| HDM |
JARID |
6.10e-95 |
316.6 |
261 |
427 |
|
| Organism |
Arabidopsis thaliana |
| NCBI Taxa ID |
3702 |
Functional Description
(View)Functional Description
Histone demethylase that demethylates 'Lys-4' (H3K4me) of histone H3 with a specific activity for H3K4me3. No activity on H3K4me2, H3K4me1, H3K9me3/2, H3K27me3/2 and H3K36me3/2. Involved in the control of flowering time by demethylating H3K4me3 at the FLC locus and repressing its expression. The repression of FLC level and reduction in H3K4me3 at the FLC locus results in induction of the flowering activator FT, which is a downstream target of FLC. |
Histone demethylase that demethylates 'Lys-4' (H3K4me) of histone H3 with a specific activity for H3K4me3. No activity on H3K4me2, H3K4me1, H3K9me3/2, H3K27me3/2 and H3K36me3/2. Involved in the control of flowering time by demethylating H3K4me3 at the FLC locus and repressing its expression. The repression of FLC level and reduction in H3K4me3 at the FLC locus results in induction of the flowering activator FT, which is a downstream target of FLC.
|
| Domain Profile |
HDM JARID
JARID.txt 1 eyaesgwnlnnlpvleesvlahinadisgvkvpwlyvgmcfsafcwhvedhwsysinylhfgepkvwygvpgsaaekleevlkklapelfesqpdllh 98
+y++sgwnlnnl++l++s+l++++++isgv+vpwlyvgmcfs+fcwhved+++ys+ny+hfgepkvwygvpgs+a+ le++++k++p+lf++qpdllh
AT2G34880.1 261 KYISSGWNLNNLARLQGSLLSFEDCEISGVQVPWLYVGMCFSTFCWHVEDNHLYSLNYHHFGEPKVWYGVPGSHATGLEKAMRKHLPDLFDEQPDLLH 358
69************************************************************************************************ PP
JARID.txt 99 qlvtllnpnilkeegvpvyrtnqkagefvitfprayhsgfnqgfnfaeavnfatvdwlaagreavesys 167
+lvt+++p+ilk+egvpvyr++q+age+v+tfprayhsgfn+gfn+aeavn+a+vdwla+g++ave ys
AT2G34880.1 359 ELVTQFSPTILKNEGVPVYRAVQNAGEYVLTFPRAYHSGFNCGFNCAEAVNVAPVDWLAHGQNAVEIYS 427
*******************************************************************96 PP
|
Protein Sequence
(Fasta) | MEPFSAAQNK EDKDTSVEPP RRRCHRKNKG TNVEPPSSPY HPKVLARWDP ANEKRPDIGE 60
APVFHPTSEE FEDTLAYIEK IRPLAESFGI CRIVPPSNWS PPCRLKGDSI WKNKNFPTRV 120
QFVDLLQNRG PVKKKTPKGR KRKRGKYSRT VAPKKRNGSV SKSVSTPKAT EEENFGFESG 180
PEFTLEKFEK YAQDFKDSYF ERKDNVGDPS VEEIEGEYWR IIEKETNEVK VLYGTDLENP 240
ILGSGFSKGV KIPTRRNDMD KYISSGWNLN NLARLQGSLL SFEDCEISGV QVPWLYVGMC 300
FSTFCWHVED NHLYSLNYHH FGEPKVWYGV PGSHATGLEK AMRKHLPDLF DEQPDLLHEL 360
VTQFSPTILK NEGVPVYRAV QNAGEYVLTF PRAYHSGFNC GFNCAEAVNV APVDWLAHGQ 420
NAVEIYSQET RKTSLSHDKI LLGAAFEAVK SLSAHGEDNT KRFSWKRFCG KDGIITKAIE 480
ARLRMEEKRI EALGNGFSLV KMDKDFDSNC ERECISCFSD LHLSATGCKN CSSLEEYGCT 540
KHDICSCEGK DRFIFLRYTI DELSSLVRAL EGESDDLKAW LSKVMEGCSE TQKGESSGII 600
VKEKQVQEEC FDLNGECNKS SEICEDASIM DLAAYHVEPI NLGFLVVGKL WCNKHAIFPK 660
GFKSRVKFYN VQDPMRISYY VSEIVDAGLL GPLFKVTLEE SQDESFSYAS PQKCWEMVLL 720
RVKEEIMRRS NQKQDVHMLE SIDGLKMFGF RSPFIVQATE ALDPNHGQVE YWNHKNEKDS 780
LEMKDCFMSN SSQSLSKARL FGVDLN 806Protein Fasta Sequence
>AT2G34880.1|JMJ15;JARID1family|Arabidopsis thaliana
MEPFSAAQNKEDKDTSVEPPRRRCHRKNKGTNVEPPSSPYHPKVLARWDPANEKRPDIGEAPVFHPTSEEFEDTLAYIEKIRPLAESFGICRIVPPSNWSPPCRLKGDSIWKNKNFPTRVQFVDLLQNRGPVKKKTPKGRKRKRGKYSRTVAPKKRNGSVSKSVSTPKATEEENFGFESGPEFTLEKFEKYAQDFKDSYFERKDNVGDPSVEEIEGEYWRIIEKETNEVKVLYGTDLENPILGSGFSKGVKIPTRRNDMDKYISSGWNLNNLARLQGSLLSFEDCEISGVQVPWLYVGMCFSTFCWHVEDNHLYSLNYHHFGEPKVWYGVPGSHATGLEKAMRKHLPDLFDEQPDLLHELVTQFSPTILKNEGVPVYRAVQNAGEYVLTFPRAYHSGFNCGFNCAEAVNVAPVDWLAHGQNAVEIYSQETRKTSLSHDKILLGAAFEAVKSLSAHGEDNTKRFSWKRFCGKDGIITKAIEARLRMEEKRIEALGNGFSLVKMDKDFDSNCERECISCFSDLHLSATGCKNCSSLEEYGCTKHDICSCEGKDRFIFLRYTIDELSSLVRALEGESDDLKAWLSKVMEGCSETQKGESSGIIVKEKQVQEECFDLNGECNKSSEICEDASIMDLAAYHVEPINLGFLVVGKLWCNKHAIFPKGFKSRVKFYNVQDPMRISYYVSEIVDAGLLGPLFKVTLEESQDESFSYASPQKCWEMVLLRVKEEIMRRSNQKQDVHMLESIDGLKMFGFRSPFIVQATEALDPNHGQVEYWNHKNEKDSLEMKDCFMSNSSQSLSKARLFGVDLN |
Nucleotide Sequence
(Fasta) | ATGGAGCCTT TCAGTGCTGC TCAGAACAAA GAGGACAAGG ACACTAGCGT AGAACCTCCT 60
CGTAGGCGTT GTCATCGAAA GAACAAGGGC ACTAATGTAG AACCTCCTAG TAGTCCGTAT 120
CATCCGAAGG TTCTTGCTAG ATGGGATCCG GCTAATGAAA AGAGGCCAGA CATTGGTGAA 180
GCTCCAGTAT TCCACCCTAC ATCAGAGGAG TTTGAAGATA CGCTTGCTTA CATAGAAAAA 240
ATACGTCCCT TAGCTGAATC ATTTGGTATT TGTCGAATCG TGCCACCGTC GAATTGGTCT 300
CCTCCTTGCC GGCTTAAAGG GGATAGTATA TGGAAGAATA AAAATTTCCC AACCCGTGTT 360
CAGTTTGTTG ACCTGCTTCA GAACAGAGGA CCCGTGAAGA AGAAGACACC TAAAGGAAGG 420
AAACGGAAAC GAGGAAAATA CTCAAGAACC GTCGCCCCCA AGAAACGAAA TGGCTCTGTT 480
TCTAAATCAG TTTCTACCCC CAAGGCGACC GAAGAAGAGA ATTTTGGTTT CGAATCTGGT 540
CCAGAATTTA CTCTTGAGAA GTTTGAGAAA TACGCTCAAG ATTTCAAAGA CTCCTACTTT 600
GAAAGAAAAG ACAATGTTGG AGATCCATCT GTTGAGGAGA TCGAAGGAGA GTACTGGAGA 660
ATCATTGAGA AAGAAACAAA TGAAGTTAAG GTATTGTATG GGACGGATTT GGAGAATCCC 720
ATACTTGGAA GCGGTTTCTC CAAAGGGGTA AAAATTCCAA CCAGAAGAAA TGATATGGAT 780
AAATACATAT CTTCTGGTTG GAATTTGAAC AACCTCGCCC GTCTGCAGGG ATCTCTACTA 840
TCCTTTGAGG ATTGTGAGAT CTCAGGGGTT CAGGTGCCAT GGCTCTATGT GGGCATGTGC 900
TTTTCAACGT TTTGTTGGCA TGTTGAGGAC AATCATCTAT ATTCACTGAA CTATCATCAC 960
TTTGGCGAGC CAAAAGTATG GTACGGAGTT CCGGGAAGCC ATGCAACTGG GCTAGAGAAG 1020
GCAATGAGAA AACATCTACC AGATTTGTTC GATGAACAAC CTGATCTACT TCATGAACTG 1080
GTTACTCAGT TTTCTCCAAC GATTTTGAAA AATGAGGGAG TCCCGGTTTA TCGAGCTGTT 1140
CAGAATGCAG GGGAGTATGT TCTAACATTC CCTAGAGCAT ATCATTCGGG TTTCAACTGC 1200
GGATTCAACT GTGCAGAAGC GGTGAATGTG GCTCCGGTTG ATTGGCTGGC TCATGGACAG 1260
AATGCTGTGG AAATATATAG CCAAGAGACT CGGAAAACGT CTCTATCTCA TGACAAAATT 1320
CTCCTTGGAG CAGCTTTTGA AGCTGTTAAG TCCCTCTCAG CACATGGGGA AGATAATACA 1380
AAAAGGTTCA GCTGGAAGAG ATTCTGTGGG AAGGACGGTA TCATAACTAA GGCCATCGAG 1440
GCACGGTTAC GGATGGAAGA AAAAAGAATT GAGGCTCTTG GAAATGGTTT CAGCTTGGTA 1500
AAGATGGATA AAGACTTTGA TTCAAACTGT GAAAGGGAAT GCATCTCTTG CTTTAGTGAC 1560
TTGCATCTCT CTGCTACTGG CTGCAAGAAT TGCTCATCTC TCGAAGAATA TGGTTGCACG 1620
AAACACGATA TTTGTTCATG TGAAGGGAAA GACCGTTTCA TTTTTCTTCG TTACACCATA 1680
GATGAGTTAA GCTCATTGGT AAGAGCATTG GAAGGTGAAT CAGATGATCT AAAAGCTTGG 1740
CTTTCCAAAG TCATGGAAGG TTGTTCAGAG ACTCAGAAGG GAGAATCTAG TGGGATTATC 1800
GTTAAGGAAA AGCAGGTACA AGAAGAATGT TTTGATCTGA ATGGTGAGTG TAATAAATCT 1860
TCTGAGATAT GTGAGGATGC ATCCATCATG GACTTAGCTG CTTATCATGT TGAACCTATA 1920
AATCTTGGGT TCTTGGTCGT GGGAAAGCTT TGGTGTAACA AGCATGCTAT ATTTCCAAAA 1980
GGGTTTAAGA GTCGTGTTAA GTTCTATAAC GTGCAAGATC CAATGAGAAT AAGCTATTAC 2040
GTCTCTGAGA TTGTAGATGC AGGACTTCTG GGTCCACTCT TCAAGGTTAC TTTGGAAGAA 2100
TCTCAAGACG AGAGCTTCTC TTATGCCTCA CCTCAGAAGT GCTGGGAAAT GGTGTTGCTT 2160
AGAGTTAAGG AAGAGATCAT GAGACGCAGC AACCAAAAAC AAGATGTCCA TATGTTGGAA 2220
AGCATCGATG GGTTAAAAAT GTTTGGCTTT CGCTCTCCGT TTATTGTTCA GGCCACTGAG 2280
GCTCTTGACC CGAACCATGG CCAAGTGGAG TATTGGAACC ATAAGAATGA GAAGGATTCG 2340
CTGGAAATGA AAGATTGCTT CATGTCAAAT TCTTCCCAGA GCTTAAGCAA AGCAAGACTT 2400
TTTGGGGTTG ATTTGAATTG A
2422Nucleotide Fasta Sequence
>AT2G34880.1|JARID|Arabidopsis thaliana
ATGGAGCCTTTCAGTGCTGCTCAGAACAAAGAGGACAAGGACACTAGCGTAGAACCTCCTCGTAGGCGTTGTCATCGAAAGAACAAGGGCACTAATGTAGAACCTCCTAGTAGTCCGTATCATCCGAAGGTTCTTGCTAGATGGGATCCGGCTAATGAAAAGAGGCCAGACATTGGTGAAGCTCCAGTATTCCACCCTACATCAGAGGAGTTTGAAGATACGCTTGCTTACATAGAAAAAATACGTCCCTTAGCTGAATCATTTGGTATTTGTCGAATCGTGCCACCGTCGAATTGGTCTCCTCCTTGCCGGCTTAAAGGGGATAGTATATGGAAGAATAAAAATTTCCCAACCCGTGTTCAGTTTGTTGACCTGCTTCAGAACAGAGGACCCGTGAAGAAGAAGACACCTAAAGGAAGGAAACGGAAACGAGGAAAATACTCAAGAACCGTCGCCCCCAAGAAACGAAATGGCTCTGTTTCTAAATCAGTTTCTACCCCCAAGGCGACCGAAGAAGAGAATTTTGGTTTCGAATCTGGTCCAGAATTTACTCTTGAGAAGTTTGAGAAATACGCTCAAGATTTCAAAGACTCCTACTTTGAAAGAAAAGACAATGTTGGAGATCCATCTGTTGAGGAGATCGAAGGAGAGTACTGGAGAATCATTGAGAAAGAAACAAATGAAGTTAAGGTATTGTATGGGACGGATTTGGAGAATCCCATACTTGGAAGCGGTTTCTCCAAAGGGGTAAAAATTCCAACCAGAAGAAATGATATGGATAAATACATATCTTCTGGTTGGAATTTGAACAACCTCGCCCGTCTGCAGGGATCTCTACTATCCTTTGAGGATTGTGAGATCTCAGGGGTTCAGGTGCCATGGCTCTATGTGGGCATGTGCTTTTCAACGTTTTGTTGGCATGTTGAGGACAATCATCTATATTCACTGAACTATCATCACTTTGGCGAGCCAAAAGTATGGTACGGAGTTCCGGGAAGCCATGCAACTGGGCTAGAGAAGGCAATGAGAAAACATCTACCAGATTTGTTCGATGAACAACCTGATCTACTTCATGAACTGGTTACTCAGTTTTCTCCAACGATTTTGAAAAATGAGGGAGTCCCGGTTTATCGAGCTGTTCAGAATGCAGGGGAGTATGTTCTAACATTCCCTAGAGCATATCATTCGGGTTTCAACTGCGGATTCAACTGTGCAGAAGCGGTGAATGTGGCTCCGGTTGATTGGCTGGCTCATGGACAGAATGCTGTGGAAATATATAGCCAAGAGACTCGGAAAACGTCTCTATCTCATGACAAAATTCTCCTTGGAGCAGCTTTTGAAGCTGTTAAGTCCCTCTCAGCACATGGGGAAGATAATACAAAAAGGTTCAGCTGGAAGAGATTCTGTGGGAAGGACGGTATCATAACTAAGGCCATCGAGGCACGGTTACGGATGGAAGAAAAAAGAATTGAGGCTCTTGGAAATGGTTTCAGCTTGGTAAAGATGGATAAAGACTTTGATTCAAACTGTGAAAGGGAATGCATCTCTTGCTTTAGTGACTTGCATCTCTCTGCTACTGGCTGCAAGAATTGCTCATCTCTCGAAGAATATGGTTGCACGAAACACGATATTTGTTCATGTGAAGGGAAAGACCGTTTCATTTTTCTTCGTTACACCATAGATGAGTTAAGCTCATTGGTAAGAGCATTGGAAGGTGAATCAGATGATCTAAAAGCTTGGCTTTCCAAAGTCATGGAAGGTTGTTCAGAGACTCAGAAGGGAGAATCTAGTGGGATTATCGTTAAGGAAAAGCAGGTACAAGAAGAATGTTTTGATCTGAATGGTGAGTGTAATAAATCTTCTGAGATATGTGAGGATGCATCCATCATGGACTTAGCTGCTTATCATGTTGAACCTATAAATCTTGGGTTCTTGGTCGTGGGAAAGCTTTGGTGTAACAAGCATGCTATATTTCCAAAAGGGTTTAAGAGTCGTGTTAAGTTCTATAACGTGCAAGATCCAATGAGAATAAGCTATTACGTCTCTGAGATTGTAGATGCAGGACTTCTGGGTCCACTCTTCAAGGTTACTTTGGAAGAATCTCAAGACGAGAGCTTCTCTTATGCCTCACCTCAGAAGTGCTGGGAAATGGTGTTGCTTAGAGTTAAGGAAGAGATCATGAGACGCAGCAACCAAAAACAAGATGTCCATATGTTGGAAAGCATCGATGGGTTAAAAATGTTTGGCTTTCGCTCTCCGTTTATTGTTCAGGCCACTGAGGCTCTTGACCCGAACCATGGCCAAGTGGAGTATTGGAACCATAAGAATGAGAAGGATTCGCTGGAAATGAAAGATTGCTTCATGTCAAATTCTTCCCAGAGCTTAAGCAAAGCAAGACTTTTTGGGGTTGATTTGAATTGA
|
| Sequence Source |
Ensembl |
| Keyword |
KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0223--Dioxygenase
KW-0408--Iron
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0560--Oxidoreductase
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
--
|
| Interpro |
IPR003889--FYrich_C
IPR003888--FYrich_N
IPR003347--JmjC_dom
IPR003349--JmjN
IPR004198--Znf_C5HC2
|
| PROSITE |
PS51543--FYRC
PS51542--FYRN
PS51184--JMJC
PS51183--JMJN
|
| Pfam |
PF05965--FYRC
PF05964--FYRN
PF02373--JmjC
PF02375--JmjN
PF02928--zf-C5HC2
|
| Gene Ontology |
GO:0005634--C:nucleus
GO:0051213--F:dioxygenase activity
GO:0034647--F:histone demethylase activity (H3-trimethyl-K4 specific)
GO:0046872--F:metal ion binding
GO:0003700--F:transcription factor activity, sequence-specific DNA binding
GO:0009793--P:embryo development ending in seed dormancy
GO:0034721--P:histone H3-K4 demethylation, trimethyl-H3-K4-specific
GO:0009555--P:pollen development
GO:0009909--P:regulation of flower development
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated
|
| Orthology |
|
| Created Date |
25-Jun-2016 |
