WERAM Information


Tag Content
WERAM ID WERAM-Art-0030
Ensembl Protein ID AT1G76710.2
Uniprot Accession Q84WW6; ASHH1_ARATH; C0SV35; Q945S9; Q9SRE2
Genbank Protein ID NP_177797.2; NP_974158.1
Protein Name Histone-lysine N-methyltransferase ASHH1
Genbank Nucleotide ID NM_106321.3; NM_202429.1
Gene Name ASHH1;SDG26
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
AT1G76710 AT1G76710.2 AT1G76710.2
AT1G76710 AT1G76710.1 AT1G76710.1
Details
Type Family Domain Substrates AA References (PMIDs)
HMT SET2 SET H3K36 K 20703330; 26854085; 26484201
Status Reviewed
Classification
Type Family E-value Score Start End
HMT SET2 8.50e-51 171.8 90 206
HMT SET1 4.90e-32 111.3 98 206
Organism Arabidopsis thaliana
NCBI Taxa ID 3702
Functional Description
(View)
Histone methyltransferase involved in regulation of flowering time. Required for the expression of the SOC1/AGL20 gene. Required for histone H3 trimethylation on 'Lys-4' H3K4me3 at the SOC1 locus. Prevents trimethylation on 'Lys-27' H3K276me3 at the same locus.
Domain Profile
  HMT SET2

     SET2.txt   2 kveliktekkGyGlrakeeikkdefileYvGevidekeakkRlkeyeeekvkdfYlleldkdeviDatkkGnlaRfinhsCePncetqkwtvegelrv 99 
k++lik+e +G+Gl+a eeik+++fi+eY+Gevi++keakkR+++ye+++vkd+Y+++l+++e+iDatkkG+laRfinhsC+Pncet+kw+v ge+rv
AT1G76710.2 90 KTKLIKCEGRGWGLVALEEIKAGQFIMEYCGEVISWKEAKKRAQTYETHGVKDAYIISLNASEAIDATKKGSLARFINHSCRPNCETRKWNVLGEVRV 187
789*********************************************************************************************** PP
SET2.txt 100 glfakkkikkgeeltfdYn 118
g+fak++i+ ++el++dYn
AT1G76710.2 188 GIFAKESISPRTELAYDYN 206
******************8 PP

  HMT SET1

     SET1.txt  10 ikglglvakkeiekeelviEYvGevirsevadkrekeyekkeig.vylfrldedaevvvdatkkgniarfinhscepNceakvvavdgekkiviyakr 106
+g+glva +ei+++++++EY+Gevi+ ++a+kr ++ye+++++ y+ +l+ + +datkkg+ arfinhsc+pNce++ +v ge +++i+ak
AT1G76710.2 98 GRGWGLVALEEIKAGQFIMEYCGEVISWKEAKKRAQTYETHGVKdAYIISLNAS--EAIDATKKGSLARFINHSCRPNCETRKWNVLGEVRVGIFAKE 193
469*****************************************9*********..99**************************************** PP
SET1.txt 107 aIekgeeltydYk 119
+I+ +el ydY+
AT1G76710.2 194 SISPRTELAYDYN 206
************7 PP

Protein Sequence
(Fasta)
MQFSCDPDQE GDELPQYEHI YQNDFSYRKH KKQKEEDISI CECKFDFGDP DSACGERCLN 60
VITNTECTPG YCPCGVYCKN QKFQKCEYAK TKLIKCEGRG WGLVALEEIK AGQFIMEYCG 120
EVISWKEAKK RAQTYETHGV KDAYIISLNA SEAIDATKKG SLARFINHSC RPNCETRKWN 180
VLGEVRVGIF AKESISPRTE LAYDYNFEWY GGAKVRCLCG AVACSGFLGA KSRGFQEDTY 240
VWEDGDDRYS VDKIPVYDSA EDELTSEPSK NGESNTNEEK EKDISTENHL ESTALNIQQQ 300
SDSTPTPMEE DVVTETVKTE TSEDMKLLSQ NSQEDSSPKT AIVSRVHGNI SKIKSESLPK 360
KRGRPFSGGK TKNVAQKHVD IANVVQLLAT KEAQDEVLKY EEVKKEAAVR LSSLYDEIRP 420
AIEEHERDSQ DSVATSVAEK WIQASCNKLK AEFDLYSSVI KNIASTPIKP QDTKTKVAEA 480
GNEDHIKLLE AK 492
Nucleotide Sequence
(Fasta)
CCAATATCCA ATTTTGTGTG TTTGCAAATA AATATGTGTT AAGTAATGTG GTTTCGTTTC 60
TAGCTGCAAG TTTCTTCCTT TCCAAAGGTT TGTGTCGATC TTAAAATCCC AGAGTTTGAT 120
AAACCTAATT CTCTCCTTCC GTTTTTAATT TTGTAGAAAC TTGACCTATA CTAGGCCCTG 180
AGTCTGATTG CGAGAATCGC TGACAAAAAA ATGCAATTTT CTTGTGATCC TGATCAAGAA 240
GGAGATGAGC TGCCACAATA TGAACACATT TATCAAAATG ACTTCTCTTA TCGAAAGCAC 300
AAGAAACAAA AGGAAGAAGA TATATCTATC TGCGAATGCA AGTTTGATTT CGGAGACCCT 360
GACAGTGCTT GTGGTGAGAG ATGCCTCAAT GTCATTACCA ACACTGAATG TACTCCTGGT 420
TACTGCCCCT GTGGTGTCTA TTGCAAGAAT CAGAAGTTCC AAAAATGTGA ATACGCCAAA 480
ACAAAGTTGA TCAAGTGTGA AGGTCGTGGT TGGGGACTAG TGGCTCTTGA AGAGATAAAG 540
GCGGGGCAAT TTATAATGGA GTACTGTGGT GAAGTAATAT CATGGAAAGA AGCAAAGAAG 600
AGGGCTCAAA CTTATGAAAC TCATGGTGTC AAGGATGCAT ACATTATATC TCTCAATGCA 660
TCTGAGGCTA TTGATGCCAC TAAGAAGGGA AGCCTTGCTA GGTTTATAAA TCATTCATGT 720
AGACCAAATT GTGAGACGAG GAAGTGGAAT GTACTGGGAG AAGTTAGGGT TGGGATCTTT 780
GCAAAAGAGA GCATCTCTCC CCGGACCGAA TTGGCTTACG ACTATAATTT TGAATGGTAC 840
GGTGGTGCCA AAGTGCGTTG TCTCTGTGGT GCGGTTGCAT GCTCTGGATT TCTTGGAGCC 900
AAGTCTCGTG GCTTTCAGGA GGATACATAT GTATGGGAGG ATGGTGACGA TCGGTATTCA 960
GTTGATAAAA TTCCAGTCTA TGATTCTGCA GAGGACGAGC TTACATCTGA GCCTTCTAAG 1020
AATGGCGAGT CCAACACAAA TGAAGAGAAA GAGAAAGATA TCTCAACAGA GAACCATTTG 1080
GAGTCTACTG CTCTGAATAT TCAACAGCAA TCAGATTCAA CTCCAACTCC TATGGAGGAA 1140
GATGTCGTCA CGGAGACTGT TAAAACCGAA ACATCTGAAG ACATGAAGCT GCTCTCACAA 1200
AATTCACAAG AAGATTCATC GCCAAAGACT GCAATTGTAT CACGGGTTCA CGGTAACATT 1260
TCCAAGATCA AGTCCGAATC TCTTCCGAAG AAAAGAGGCA GGCCGTTTTC AGGCGGAAAA 1320
ACAAAGAATG TCGCTCAGAA GCATGTTGAC ATAGCGAATG TGGTTCAGCT ACTAGCAACC 1380
AAAGAAGCTC AAGATGAAGT TCTCAAATAC GAGGAGGTGA AGAAGGAAGC AGCAGTACGA 1440
CTCTCGTCAT TGTACGACGA GATAAGGCCG GCGATTGAGG AGCATGAAAG AGATAGCCAA 1500
GACAGTGTAG CAACAAGTGT GGCGGAGAAA TGGATACAAG CAAGCTGTAA TAAACTCAAG 1560
GCAGAGTTTG ATCTTTACTC TAGTGTAATA AAGAACATCG CTTCCACTCC CATCAAACCA 1620
CAAGACACAA AGACCAAAGT CGCGGAAGCA GGAAACGAAG ACCATATTAA ACTCTTGGAA 1680
GCCAAATGAG AATTAGCTCG GAAGGACACC TCTAATGGAC AAAAAAATAT CTTAAGAACT 1740
GGAAGCTAAC TTGGTTTACT TTTCACGTTT GAAAATGTAA TAAATATTTT TAAAATGAGA 1800
ACATTTTGTT GAAATTTAAA ATTTTAGTAA TCAAATTTTT ATTAATC 1848
Sequence Source Ensembl
Keyword

KW-0137--Centromere
KW-0156--Chromatin regulator
KW-0158--Chromosome
KW-0181--Complete proteome
KW-0287--Flowering
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
--

Interpro

IPR006560--AWS_dom
IPR003616--Post-SET_dom
IPR001214--SET_dom

PROSITE

PS51215--AWS
PS50868--POST_SET
PS50280--SET

Pfam

PF00856--SET

Gene Ontology

GO:0000775--C:chromosome, centromeric region
GO:0005634--C:nucleus
GO:0018024--F:histone-lysine N-methyltransferase activity
GO:0006281--P:DNA repair
GO:0009908--P:flower development
GO:0016571--P:histone methylation
GO:0010224--P:response to UV-B
GO:0010228--P:vegetative to reproductive phase transition of meristem

Orthology
WERAM ID Ensembl Protein ID Species Identity E-value Score
WERAM-Arl-0034 fgenesh1_pm.C_scaffold_2001622 Arabidopsis lyrata 91 0.0 930
WERAM-Brr-0080 Bra015723.1-P Brassica rapa 82 0.0 786
WERAM-Bro-0118 Bo6g120790.1 Brassica oleracea 83 0.0 782
WERAM-Pot-0069 POPTR_0005s21720.1 Populus trichocarpa 66 0.0 643
WERAM-Thc-0099 EOY16799 Theobroma cacao 65 0.0 638
WERAM-Glm-0117 GLYMA10G36720.1 Glycine max 62 2e-171 599
WERAM-Viv-0114 VIT_18s0072g00200.t01 Vitis vinifera 60 7e-171 597
WERAM-Met-0031 AES62318 Medicago truncatula 63 5e-166 581
WERAM-Mua-0009 GSMUA_Achr10P15910_001 Musa acuminata 60 4e-165 578
WERAM-Sei-0032 Si009854m Setaria italica 57 2e-159 559
WERAM-Orbr-0054 OB04G19910.1 Oryza brachyantha 56 4e-157 551
WERAM-Zem-0082 GRMZM2G147619_P03 Zea mays 56 3e-156 549
WERAM-Ors-0041 OS04T0429100-01 Oryza sativa 55 8e-156 547
WERAM-Org-0045 ORGLA04G0098200.1 Oryza glaberrima 56 8e-156 547
WERAM-Tra-0042 Traes_2AL_F2EFC6E67.1 Triticum aestivum 55 6e-155 544
WERAM-Sob-0087 Sb06g016720.1 Sorghum bicolor 55 9e-155 544
WERAM-Hov-0032 MLOC_34561.1 Hordeum vulgare 58 1e-154 543
WERAM-Brd-0124 BRADI5G10110.1 Brachypodium distachyon 54 2e-154 542
WERAM-Aet-0006 EMT26549 Aegilops tauschii 55 8e-154 541
WERAM-Amt-0021 ERN08697 Amborella trichopoda 59 1e-153 540
WERAM-Orr-0043 ORUFI04G14000.1 Oryza rufipogon 54 1e-152 537
WERAM-Lep-0046 LPERR04G09490.1 Leersia perrieri 54 5e-152 535
WERAM-Orp-0044 OPUNC04G10800.1 Oryza punctata 55 2e-151 533
WERAM-Orm-0046 OMERI04G11460.1 Oryza meridionalis 53 5e-151 531
WERAM-Orl-0067 KN539428.1_FGP003 Oryza longistaminata 54 5e-148 521
WERAM-Ori-0052 BGIOSGA016424-PA Oryza indica 55 5e-146 515
WERAM-Sol-0089 Solyc07g008460.2.1 Solanum lycopersicum 55 3e-139 492
WERAM-Prp-0112 EMJ00799 Prunus persica 78 2e-112 403
WERAM-Sot-0031 PGSC0003DMT400028500 Solanum tuberosum 54 1e-110 397
WERAM-Php-0067 PP1S28_356V6.1 Physcomitrella patens 44 1e-53 208
WERAM-Chr-0033 EDP02327 Chlamydomonas reinhardtii 41 2e-53 207
WERAM-Sem-0083 EFJ16223 Selaginella moellendorffii 44 8e-53 205
WERAM-Asm-0171 ENSAMXP00000016940.1 Astyanax mexicanus 42 1e-50 198
WERAM-Leo-0048 ENSLOCP00000006757.1 Lepisosteus oculatus 41 1e-50 197
WERAM-Pes-0163 ENSPSIP00000019522.1 Pelodiscus sinensis 40 1e-49 195
WERAM-Tar-0164 ENSTRUP00000035102.1 Takifugu rubripes 41 1e-49 194
WERAM-Orn-0031 ENSONIP00000003854.1 Oreochromis niloticus 41 2e-49 194
WERAM-Mod-0123 ENSMODP00000017559.3 Monodelphis domestica 40 4e-49 193
WERAM-Gaga-0059 ENSGALP00000008825.4 Gallus gallus 40 4e-49 192
WERAM-Anp-0041 ENSAPLP00000004480.1 Anas platyrhynchos 40 5e-49 192
WERAM-Sah-0117 ENSSHAP00000012598.1 Sarcophilus harrisii 40 5e-49 192
WERAM-Fia-0033 ENSFALP00000002007.1 Ficedula albicollis 40 7e-49 192
WERAM-Tag-0003 ENSTGUP00000000172.1 Taeniopygia guttata 40 7e-49 192
WERAM-Anc-0016 ENSACAP00000002203.3 Anolis carolinensis 39 1e-48 191
WERAM-Orla-0081 ENSORLP00000010328.1 Oryzias latipes 41 1e-48 191
WERAM-Xim-0177 ENSXMAP00000014226.1 Xiphophorus maculatus 40 1e-48 191
WERAM-Pof-0017 ENSPFOP00000001631.1 Poecilia formosa 40 1e-48 191
WERAM-Ict-0161 ENSSTOP00000016952.1 Ictidomys tridecemlineatus 40 2e-48 191
WERAM-Chs-0194 ENSCSAP00000012204.1 Chlorocebus sabaeus 40 2e-48 190
WERAM-Pat-0126 ENSPTRP00000025629.4 Pan troglodytes 40 2e-48 190
WERAM-Ran-0141 ENSRNOP00000028408.5 Rattus norvegicus 40 2e-48 190
WERAM-Mum-0177 ENSMUSP00000116313.2 Mus musculus 40 2e-48 190
WERAM-Hos-0212 ENSP00000386759.3 Homo sapiens 40 2e-48 190
WERAM-Gog-0197 ENSGGOP00000025052.2 Gorilla gorilla 40 2e-48 190
WERAM-Eqc-0058 ENSECAP00000007791.1 Equus caballus 40 3e-48 190
WERAM-Poa-0125 ENSPPYP00000015574.2 Pongo abelii 40 3e-48 190
WERAM-Osl-0018 ABP00208 Ostreococcus lucimarinus 41 3e-48 190
WERAM-Aim-0141 ENSAMEP00000013463.1 Ailuropoda melanoleuca 40 3e-48 190
WERAM-Ova-0043 ENSOARP00000005431.1 Ovis aries 40 3e-48 190
WERAM-Caf-0145 ENSCAFP00000019740.3 Canis familiaris 40 3e-48 190
WERAM-Bot-0037 ENSBTAP00000003838.5 Bos taurus 40 3e-48 190
WERAM-Fec-0157 ENSFCAP00000015869.2 Felis catus 40 3e-48 190
WERAM-Paa-0066 ENSPANP00000003313.1 Papio anubis 40 3e-48 190
WERAM-Mam-0194 ENSMMUP00000027793.2 Macaca mulatta 40 3e-48 190
WERAM-Nol-0062 ENSNLEP00000007605.1 Nomascus leucogenys 40 4e-48 190
WERAM-Lac-0058 ENSLACP00000008064.1 Latimeria chalumnae 40 4e-48 189
WERAM-Cap-0096 ENSCPOP00000007389.2 Cavia porcellus 40 4e-48 189
WERAM-Meg-0030 ENSMGAP00000002517.2 Meleagris gallopavo 40 5e-48 189
WERAM-Ocp-0056 ENSOPRP00000004800.1 Ochotona princeps 40 5e-48 189
WERAM-Dan-0009 ENSDNOP00000001031.3 Dasypus novemcinctus 40 5e-48 189
WERAM-Miv-0037 MVLG_05378T0 Microbotryum violaceum 43 6e-48 189
WERAM-Tut-0177 ENSTTRP00000015037.1 Tursiops truncatus 40 6e-48 189
WERAM-Tub-0124 ENSTBEP00000013685.1 Tupaia belangeri 40 6e-48 189
WERAM-Tas-0101 ENSTSYP00000010617.1 Tarsius syrichta 40 6e-48 189
WERAM-Loa-0040 ENSLAFP00000002747.3 Loxodonta africana 40 6e-48 189
WERAM-Dar-0144 ENSDARP00000114457.1 Danio rerio 39 7e-48 189
WERAM-Orc-0024 ENSOCUP00000002465.3 Oryctolagus cuniculus 40 7e-48 189
WERAM-Vip-0107 ENSVPAP00000009702.1 Vicugna pacos 40 8e-48 189
WERAM-Orgl-0024 OGLUM02G20630.1 Oryza glumaepatula 38 8e-48 188
WERAM-Myl-0114 ENSMLUP00000009203.2 Myotis lucifugus 39 1e-47 188
WERAM-Soa-0060 ENSSARP00000006011.1 Sorex araneus 40 1e-47 188
WERAM-Ptv-0035 ENSPVAP00000003990.1 Pteropus vampyrus 40 1e-47 188
WERAM-Orni-0022 ONIVA02G22370.1 Oryza nivara 41 1e-47 187
WERAM-Caj-0020 ENSCJAP00000004202.1 Callithrix jacchus 40 2e-47 187
WERAM-Nec-0001 EFNCRP00000000016 Neurospora crassa 44 2e-46 184
WERAM-Scs-0026 EDO04606 Sclerotinia sclerotiorum 42 2e-46 184
WERAM-Cii-0057 ENSCINP00000025949.2 Ciona intestinalis 35 3e-46 183
WERAM-Sus-0061 ENSSSCP00000009255.2 Sus scrofa 43 5e-46 182
WERAM-Tum-0015 CAZ82931 Tuber melanosporum 44 9e-46 182
WERAM-Lab-0050 EDR09647 Laccaria bicolor 39 1e-45 182
WERAM-Mup-0139 ENSMPUP00000012178.1 Mustela putorius furo 41 3e-45 180
WERAM-Xet-0165 ENSXETP00000005100.3 Xenopus tropicalis 42 4e-45 179
WERAM-Gaa-0041 ENSGACP00000006025.1 Gasterosteus aculeatus 40 4e-45 179
WERAM-Pem-0013 ENSPMAP00000002102.1 Petromyzon marinus 41 5e-45 179
WERAM-Prc-0109 ENSPCAP00000009738.1 Procavia capensis 41 5e-45 179
WERAM-Asfu-0029 CADAFUAP00006520 Aspergillus fumigatus 46 5e-45 179
WERAM-Asc-0008 CADACLAP00001395 Aspergillus clavatus 46 7e-45 179
WERAM-Otg-0116 ENSOGAP00000010251.2 Otolemur garnettii 41 7e-45 179
WERAM-Asn-0025 CADANIAP00006232 Aspergillus nidulans 46 1e-44 178
WERAM-Coi-0027 EAS30731 Coccidioides immitis 46 1e-44 177
WERAM-Chg-0015 EAQ91281 Chaetomium globosum 40 2e-44 177
WERAM-Fuo-0030 FOXG_09334P0 Fusarium oxysporum 42 2e-44 177
WERAM-Scp-0013 SPAC29B12.02c.1:pep Schizosaccharomyces pombe 40 2e-44 177
WERAM-Aso-0020 CADAORAP00004002 Aspergillus oryzae 45 4e-44 176
WERAM-Asf-0029 CADAFLAP00010840 Aspergillus flavus 45 5e-44 176
WERAM-Mel-0032 EGG05344 Melampsora laricipopulina 34 6e-44 176
WERAM-Kop-0006 CAY68124 Komagataella pastoris 40 6e-44 176
WERAM-Scj-0019 EEB07769 Schizosaccharomyces japonicus 44 1e-43 174
WERAM-Usm-0014 UM02500P0 Ustilago maydis 37 1e-43 174
WERAM-Ora-0074 ENSOANP00000011168.1 Ornithorhynchus anatinus 41 1e-43 174
WERAM-Asni-0036 CADANGAP00013329 Aspergillus niger 45 2e-43 174
WERAM-Dio-0131 ENSDORP00000012311.1 Dipodomys ordii 42 3e-43 174
WERAM-Put-0020 PTTG_08628P0 Puccinia triticina 37 3e-43 174
WERAM-Spr-0007 CBQ71244 Sporisorium reilianum 36 4e-43 173
Created Date 25-Jun-2016