WERAM Information

Tag Content
WERAM ID WERAM-Sac-0033
Ensembl Protein ID YMR069W
Uniprot Accession Q04751; NAT4_YEAST; D6VZP3
Genbank Protein ID NP_013785.1
Protein Name Histone-specific N-acetyltransferase NAT4
Genbank Nucleotide ID NM_001182567.1
Gene Name NAT4;NAA40;YMR069W;YM9916.08
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
YMR069W YMR069W YMR069W
Details
Type Family Domain Substrates AA References (PMIDs)
HAT GCN5 N-acetyltransferase K 21935442
Status Reviewed
Classification
Type Family E-value Score Start End
HAT GCN5 4.90e-49 164.9 91 274
Organism Saccharomyces cerevisiae
NCBI Taxa ID 559292
Functional Description
(View)		 Responsible for the acetylation of the N-terminal residues of histones H4 and H2A.
Domain Profile
  HAT GCN5
  GCN5.txt   1 kleksrvdevl.lvlvglqkvfeaqlprm.......kkeyiarlladrkhkslv.vikkdngvvggit.frlfeeegfvE..........vvyc...avas 78 
               kl+ksr+d+vl +++++++k+++a+++r+       +k+++a++la++k+++lv v+++dngv+g++t f+l+ee+g+vE          v+y+   +vas
   YMR069W  91 KLHKSRGDQVLdACVQLIDKHLGAKYRRAsrimygnRKPWKANKLAEMKSAGLVyVCYWDNGVLGAFTsFMLTEETGLVEgdalhevsvpVIYLyevHVAS 191
               59*************************************************************************************************** PP
  GCN5.txt  79 kervkGyGkrLlnh..lkevarktrri..kff...LT.fadn.......eaigyfkkqgfskeiklpksstigyikeyegatllece 150
               ++r++G+G+rLl+h  +++var+trr+  +ff   LT f+dn       ea+g+++++g+++    p+s+ti+++++++g+++++c+
   YMR069W 192 AHRGHGIGRRLLEHalCDGVARHTRRMcdNFFgvaLTvFSDNtrarrlyEALGFYRAPGSPA----PASPTIRHTRHGGGRVVVPCD 274
               ****************************8888******************************....********************7 PP
Protein Sequence
(Fasta)		MRSSVYSENT YNCIRTSKEH LTERRRVAMA PMFQHFLNLC VEKFPESIEH KDTDGNGNFT 60
TAILEREIIY IPEDDTDSID SVDSLKCINY KLHKSRGDQV LDACVQLIDK HLGAKYRRAS 120
RIMYGNRKPW KANKLAEMKS AGLVYVCYWD NGVLGAFTSF MLTEETGLVE GDALHEVSVP 180
VIYLYEVHVA SAHRGHGIGR RLLEHALCDG VARHTRRMCD NFFGVALTVF SDNTRARRLY 240
EALGFYRAPG SPAPASPTIR HTRHGGGRVV VPCDPLYYVY CLHMP 285
Nucleotide Sequence
(Fasta)		ATGCGTTCTT CGGTATATAG TGAGAACACT TACAACTGTA TACGAACATC GAAGGAGCAC 60
CTAACAGAAA GAAGGAGGGT CGCCATGGCG CCAATGTTCC AACATTTCTT AAACTTATGC 120
GTGGAAAAAT TTCCTGAATC CATCGAGCAC AAGGATACAG ATGGAAACGG TAACTTCACC 180
ACCGCTATTT TAGAAAGGGA GATTATCTAC ATCCCCGAAG ATGACACTGA CAGTATTGAC 240
AGCGTTGACA GCCTCAAGTG TATAAACTAC AAGCTGCACA AATCTCGCGG CGACCAAGTG 300
CTGGACGCCT GTGTGCAATT GATAGACAAG CACCTGGGCG CCAAGTATCG CCGGGCCTCG 360
CGCATTATGT ACGGCAACAG GAAACCATGG AAGGCAAACA AACTCGCAGA GATGAAAAGC 420
GCCGGCCTTG TGTATGTCTG TTACTGGGAC AACGGCGTGC TAGGTGCATT TACTTCATTC 480
ATGCTTACAG AGGAGACGGG TCTCGTCGAA GGTGACGCTT TACACGAGGT TAGCGTGCCC 540
GTGATATACC TTTACGAAGT ACATGTAGCT AGCGCGCACC GCGGGCATGG AATCGGTCGG 600
CGGCTACTGG AGCATGCACT GTGCGATGGC GTAGCTCGAC ACACCCGCCG CATGTGCGAC 660
AATTTCTTCG GTGTAGCACT CACCGTATTC AGTGATAACA CTCGGGCCCG GCGACTATAT 720
GAGGCGCTTG GGTTCTACCG CGCTCCGGGA TCACCCGCAC CAGCATCACC CACAATTCGT 780
CACACGCGAC ATGGTGGGGG ACGTGTAGTC GTGCCCTGCG ATCCGCTTTA TTACGTATAT 840
TGCCTTCACA TGCCGTGA 859
Sequence Source Ensembl
Keyword

KW-0012--Acyltransferase
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0808--Transferase
--
Interpro

IPR016181--Acyl_CoA_acyltransferase
IPR000182--GNAT_dom
PROSITE

PS51186--GNAT
Pfam

PF00583--Acetyltransf_1
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0004402--F:histone acetyltransferase activity
GO:0016573--P:histone acetylation
GO:0061187--P:regulation of chromatin silencing at rDNA
Orthology
Created Date 25-Jun-2016