WERAM Information

Tag Content
WERAM ID WERAM-Sac-0025
Ensembl Protein ID YKL005C
Uniprot Accession P36106; BYE1_YEAST; D6VXT2
Genbank Protein ID NP_012921.3
Protein Name Transcription factor BYE1
Genbank Nucleotide ID NM_001179571.3
Gene Name Bye1;YKL005C;YKL150
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
YKL005C YKL005C YKL005C
Details
Type Family Domain Substrates AA References (PMIDs)
Me_Reader PHD PHD-type H3K4me K 17142463
Status Reviewed
Classification
Type Family E-value Score Start End
Me_Reader PHD 9.90e-10 36.9 74 132
Organism Saccharomyces cerevisiae
NCBI Taxa ID 559292
Functional Description
(View)		 Negative regulator of transcription elongation.
Domain Profile
  Me_Reader PHD
  PHD.txt   3 iClvCgkddegeke.......mvqCdeCddwfHlkCvklplsslpeg.....kswyCpsCk 51 
               Cl Cg ++e+ +        mvqCd+Cd+w H+kC++  + ++  g     +++yC+ C 
  YKL005C  74 RCL-CGANNENYDAaeyshgdMVQCDGCDTWQHIKCMTDGKDTID-GlmsedSKYYCELCD 132
              698.97666653334478889*****************9933332.34555589******7 PP
Protein Sequence
(Fasta)		MSVRTSSRSN KGQNKYIEYL LQEETEAPKK KRTKKKVDSA IEKNKKSDSS QEPRKDTENV 60
RTDEVDEADE GYVRCLCGAN NENYDAAEYS HGDMVQCDGC DTWQHIKCMT DGKDTIDGLM 120
SEDSKYYCEL CDPSLYAHLE TSKEAEVSED EDYHDDVYKP VNDHDDNDAD VFLDEESPRK 180
RKRSPDSAKG IHIKSKQVKK SNGSKKRNKS IDAAKSDTAE NEMPTRKDFE SEKEHKLRYN 240
AEKMFSTLFS KFIVPETIEA KLYELPDGKD VISISQEFAH NLEEELYKAC LNVEFGTLDK 300
IYTEKVRSLY SNLKDKKNLE LKAHVVEGKL PLNKLVNMNA SELANPDLQE FKEKRDKIIL 360
ENFIVEVPDK PMYVKTHKGD ELIEDIAEPQ EDILYSKDSI RLHNIDSIDS DKSKIEQTHA 420
ISKEPSPSTI INEESLNCAF LYPGLGLEFT GYLNYIGASQ KLRRDIFKEA IGDGKLYVEG 480
RLPTTTAAPY LKEISCSRAI LVYQLFPSND SESKTTFADV VDSLENKGRI AGIKPKTRYE 540
KDFYIVPSKG GEIPEILKDI LGSHNDERSE RFSRMKSDER TLFAFVVVKQ EFIH 594
Nucleotide Sequence
(Fasta)		ATGTCTGTCC GTACTTCTTC AAGATCTAAT AAGGGTCAGA ATAAATATAT TGAGTATTTG 60
TTACAGGAGG AGACTGAAGC ACCAAAGAAA AAAAGAACTA AAAAGAAAGT TGATTCAGCC 120
ATAGAGAAGA ATAAGAAGTC TGATTCTTCT CAGGAGCCAA GGAAAGATAC TGAAAATGTA 180
AGAACAGACG AAGTAGACGA AGCGGATGAG GGCTATGTTA GATGTCTGTG TGGGGCGAAC 240
AATGAAAACT ACGATGCTGC AGAATATTCG CATGGCGACA TGGTACAGTG CGATGGCTGT 300
GACACTTGGC AGCATATTAA ATGTATGACT GATGGTAAAG ACACCATAGA TGGGCTAATG 360
AGTGAAGATT CTAAGTACTA CTGTGAATTG TGCGACCCAT CATTGTATGC ACATTTGGAA 420
ACGTCAAAGG AGGCAGAGGT TTCAGAGGAT GAAGATTACC ATGATGATGT TTACAAGCCC 480
GTAAATGACC ATGATGACAA TGATGCAGAT GTCTTTCTTG ATGAGGAAAG CCCTAGGAAA 540
CGAAAAAGGA GCCCCGATAG TGCCAAAGGA ATTCATATCA AATCCAAACA GGTGAAGAAA 600
TCCAATGGGT CAAAAAAAAG GAATAAAAGC ATTGATGCCG CCAAGTCTGA TACTGCCGAA 660
AACGAAATGC CTACTAGGAA AGATTTTGAA AGCGAAAAAG AACACAAACT GAGGTATAAT 720
GCAGAAAAAA TGTTCTCTAC CTTATTTAGC AAATTCATCG TTCCCGAAAC AATTGAGGCA 780
AAACTTTATG AGCTTCCTGA TGGGAAAGAC GTTATATCGA TATCGCAAGA GTTTGCGCAC 840
AATCTGGAAG AAGAACTTTA CAAAGCTTGC CTTAACGTCG AGTTTGGTAC TTTGGACAAG 900
ATATACACAG AGAAAGTGAG GTCGTTATAC TCTAATTTAA AGGATAAAAA AAATTTGGAA 960
CTGAAGGCAC ACGTTGTCGA GGGCAAATTG CCTTTAAATA AACTGGTGAA CATGAACGCA 1020
TCTGAACTCG CAAATCCTGA CTTACAAGAA TTTAAAGAGA AAAGGGATAA GATTATCTTA 1080
GAAAATTTTA TCGTGGAGGT ACCTGACAAA CCCATGTACG TTAAGACCCA CAAGGGTGAT 1140
GAGCTGATCG AAGATATCGC TGAACCTCAA GAGGATATTT TGTACTCAAA AGACAGCATA 1200
AGATTACACA ACATTGACAG TATCGACAGC GATAAGAGTA AAATAGAACA GACTCATGCC 1260
ATTTCGAAAG AACCCAGCCC AAGTACAATA ATCAACGAAG AATCTTTAAA CTGCGCATTT 1320
TTGTATCCCG GCTTAGGACT TGAGTTTACA GGTTACCTAA ACTACATTGG GGCTTCACAA 1380
AAGTTAAGAC GGGATATTTT CAAGGAAGCC ATTGGTGACG GAAAACTGTA TGTAGAAGGG 1440
CGCTTACCTA CAACCACTGC TGCACCATAT CTTAAGGAAA TTTCTTGCTC TAGAGCTATA 1500
TTAGTATACC AATTATTTCC TTCGAATGAT AGTGAAAGTA AGACAACTTT TGCCGACGTT 1560
GTAGACTCCC TGGAAAACAA AGGTCGCATT GCAGGTATAA AGCCAAAAAC TAGATACGAG 1620
AAGGATTTTT ATATCGTTCC ATCGAAGGGC GGTGAAATTC CTGAAATTTT GAAAGATATT 1680
TTAGGCAGTC ACAATGATGA AAGATCTGAG AGATTTTCGC GAATGAAATC AGATGAAAGA 1740
ACATTATTCG CATTTGTTGT CGTGAAACAG GAATTTATCC ATTAA 1786
Sequence Source Ensembl
Keyword

KW-0002--3D-structure
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0678--Repressor
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger
--
Interpro

IPR012921--SPOC_C
IPR003618--TFIIS_cen_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS51321--TFIIS_CENTRAL
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2
Pfam

PF00628--PHD
PF07744--SPOC
PF07500--TFIIS_M
Gene Ontology

GO:0005634--C:nucleus
GO:0003682--F:chromatin binding
GO:0035064--F:methylated histone binding
GO:0008270--F:zinc ion binding
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0006351--P:transcription, DNA-templated
Orthology
WERAM ID Ensembl Protein ID Species Identity E-value Score
WERAM-Cag-0035 CAG62772 Candida glabrata 30 9e-61 232
WERAM-Nec-0011 EFNCRP00000001625 Neurospora crassa 25 8e-11 66.2
WERAM-Phn-0025 SNOT_12292 Phaeosphaeria nodorum 33 1e-10 65.5
WERAM-Scj-0013 EEB06660 Schizosaccharomyces japonicus 42 2e-10 65.1
WERAM-Pem-0025 ENSPMAP00000003498.1 Petromyzon marinus 37 7e-09 60.1
WERAM-Pytr-0023 EDU49451 Pyrenophora triticirepentis 29 8e-09 59.7
WERAM-Kop-0002 CAY67515 Komagataella pastoris 40 1e-08 58.9
WERAM-Chg-0040 EAQ85398 Chaetomium globosum 32 2e-08 58.5
WERAM-Dar-0073 ENSDARP00000043439.5 Danio rerio 26 3e-08 57.8
WERAM-Caf-0179 ENSCAFP00000024919.4 Canis familiaris 35 4e-08 57.4
WERAM-Coi-0006 EAS35986 Coccidioides immitis 33 9e-08 56.2
WERAM-Asf-0021 CADAFLAP00009941 Aspergillus flavus 31 9e-08 56.2
WERAM-Fec-0122 ENSFCAP00000011217.3 Felis catus 37 1e-07 56.2
WERAM-Aim-0001 ENSAMEP00000000048.1 Ailuropoda melanoleuca 34 1e-07 55.8
WERAM-Ast-0018 CADATEAP00005962 Aspergillus terreus 28 1e-07 55.8
WERAM-Asni-0026 CADANGAP00008835 Aspergillus niger 31 1e-07 55.8
WERAM-Meg-0066 ENSMGAP00000006074.2 Meleagris gallopavo 40 2e-07 55.5
WERAM-Ect-0013 ENSETEP00000000939.1 Echinops telfairi 39 2e-07 55.1
WERAM-Mup-0063 ENSMPUP00000005424.1 Mustela putorius furo 35 2e-07 55.1
WERAM-Myl-0149 ENSMLUP00000012265.2 Myotis lucifugus 35 2e-07 55.1
WERAM-Asc-0032 CADACLAP00007799 Aspergillus clavatus 27 3e-07 54.7
WERAM-Anc-0096 ENSACAP00000009082.3 Anolis carolinensis 23 4e-07 54.3
WERAM-Otg-0100 ENSOGAP00000008607.2 Otolemur garnettii 37 4e-07 53.9
WERAM-Vip-0083 ENSVPAP00000007858.1 Vicugna pacos 37 5e-07 53.9
WERAM-Ocp-0053 ENSOPRP00000004587.1 Ochotona princeps 37 5e-07 53.9
WERAM-Hos-0093 ENSP00000357330.3 Homo sapiens 37 5e-07 53.9
WERAM-Pyt-0013 EFQ92822 Pyrenophora teres 28 5e-07 53.9
WERAM-Paa-0029 ENSPANP00000005654.1 Papio anubis 37 5e-07 53.5
WERAM-Pat-0013 ENSPTRP00000002411.3 Pan troglodytes 37 5e-07 53.5
WERAM-Chh-0018 ENSCHOP00000001855.1 Choloepus hoffmanni 37 5e-07 53.5
WERAM-Chs-0022 ENSCSAP00000016009.1 Chlorocebus sabaeus 37 5e-07 53.5
WERAM-Caj-0092 ENSCJAP00000015181.2 Callithrix jacchus 37 5e-07 53.5
WERAM-Poa-0004 ENSPPYP00000000864.2 Pongo abelii 37 5e-07 53.5
WERAM-Bot-0048 ENSBTAP00000005172.5 Bos taurus 37 5e-07 53.5
WERAM-Gog-0128 ENSGGOP00000010946.2 Gorilla gorilla 37 5e-07 53.5
WERAM-Ova-0035 ENSOARP00000004767.1 Ovis aries 37 5e-07 53.5
WERAM-Eqc-0151 ENSECAP00000016148.1 Equus caballus 37 5e-07 53.5
WERAM-Tub-0092 ENSTBEP00000010737.1 Tupaia belangeri 37 6e-07 53.5
WERAM-Sus-0043 ENSSSCP00000006936.2 Sus scrofa 37 6e-07 53.5
WERAM-Met-0101 AES88651 Medicago truncatula 38 6e-07 53.5
WERAM-Soa-0011 ENSSARP00000001033.1 Sorex araneus 37 6e-07 53.5
WERAM-Tut-0149 ENSTTRP00000012646.1 Tursiops truncatus 37 6e-07 53.5
WERAM-Mod-0150 ENSMODP00000021257.2 Monodelphis domestica 37 6e-07 53.5
WERAM-Cap-0050 ENSCPOP00000004321.2 Cavia porcellus 37 6e-07 53.5
WERAM-Dan-0138 ENSDNOP00000030955.1 Dasypus novemcinctus 37 6e-07 53.5
WERAM-Sah-0094 ENSSHAP00000010988.1 Sarcophilus harrisii 37 6e-07 53.5
WERAM-Orc-0146 ENSOCUP00000012882.3 Oryctolagus cuniculus 37 7e-07 53.5
WERAM-Scp-0049 SPCC645.13.1:pep Schizosaccharomyces pombe 38 7e-07 53.1
WERAM-Asm-0091 ENSAMXP00000009496.1 Astyanax mexicanus 35 7e-07 53.1
WERAM-Asn-0031 CADANIAP00008424 Aspergillus nidulans 28 8e-07 53.1
WERAM-Ved-0018 EGY14144 Verticillium dahliae 24 9e-07 52.8
WERAM-Ran-0136 ENSRNOP00000027629.6 Rattus norvegicus 33 1e-06 52.8
WERAM-Tum-0002 CAZ79493 Tuber melanosporum 31 1e-06 52.8
WERAM-Kll-0022 CAG99888 Kluyveromyces lactis 32 1e-06 52.8
WERAM-Mum-0089 ENSMUSP00000088451.4 Mus musculus 36 1e-06 52.4
WERAM-Mae-0076 ENSMEUP00000007694.1 Macropus eugenii 37 1e-06 52.4
WERAM-Lem-0036 CBX96221 Leptosphaeria maculans 28 1e-06 52.4
WERAM-Asfu-0006 CADAFUAP00001898 Aspergillus fumigatus 28 2e-06 52.0
WERAM-Tag-0191 ENSTGUP00000017698.1 Taeniopygia guttata 35 2e-06 52.0
WERAM-Mao-0034 MGG_12463T0 Magnaporthe oryzae 39 2e-06 52.0
WERAM-Gaa-0026 ENSGACP00000004363.3 Gasterosteus aculeatus 38 2e-06 52.0
WERAM-Anp-0113 ENSAPLP00000012903.1 Anas platyrhynchos 36 2e-06 51.6
WERAM-Gaga-0134 ENSGALP00000023545.4 Gallus gallus 36 2e-06 51.6
WERAM-Fia-0043 ENSFALP00000002960.1 Ficedula albicollis 36 3e-06 51.2
WERAM-Ptv-0188 ENSPVAP00000016847.1 Pteropus vampyrus 29 3e-06 51.2
WERAM-Mel-0025 EGG01272 Melampsora laricipopulina 30 4e-06 50.4
WERAM-Sem-0144 EFJ28610 Selaginella moellendorffii 33 8e-06 49.7
WERAM-Aso-0002 CADAORAP00000519 Aspergillus oryzae 25 9e-06 49.7
Created Date 25-Jun-2016