WERAM Information

Tag Content
WERAM ID WERAM-Cae-0010
Ensembl Protein ID K01G5.2a
Uniprot Accession G5EDE2; G5EDE2_CAEEL
Genbank Protein ID NP_001022652.1
Protein Name Chromo-domain protein
Genbank Nucleotide ID NM_001027481.4
Gene Name HPL-2;hpl-2K01G5.2a;CELE_K01G5.2
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
WBGene00001996 K01G5.2a K01G5.2a
WBGene00001996 K01G5.2b K01G5.2b
WBGene00001996 K01G5.2c K01G5.2c
Details
Type Family Domain Substrates AA References (PMIDs)
Me_Reader Chromodomain Chromo H3K9me2/3 K 24348272
Status Reviewed
Classification
Type Family E-value Score Start End
Me_Reader Chromodomain 6.70e-21 74.7 19 76
Organism Caenorhabditis elegans
NCBI Taxa ID 6239
Functional Description
(View)
Domain Profile
  Me_Reader Chromodomain
  Chromodomain.txt  1 FeverivdkkelrkgeveYlVrWkGynksddtWepeenLlckelleefekkkekkkkq 58
                      F+ve+++dk++ + g+ e+l++W+G+++sd++Wep+enL+c+e+l+efe++ +k++k 
          K01G5.2a 19 FMVEKVLDKRTGKAGRDEFLIQWQGFPESDSSWEPRENLQCVEMLDEFEREFSKREKP 76
                      99****************************************************9986 PP
Protein Sequence
(Fasta)		MSSKSTKRAK IEDPKDNVFM VEKVLDKRTG KAGRDEFLIQ WQGFPESDSS WEPRENLQCV 60
EMLDEFEREF SKREKPIRKR HSQKPEPSED QADPEEDKDE KKETNQNDKF SLEGKQLKCI 120
VGLTKGPGEL HFLCKFSDDT ARLLPAKEVN SRYPSQVIRY YESKLTIQDP KADEL 175
Nucleotide Sequence
(Fasta)		AGCAATTTCA AAAATGTCGA GCAAATCAAC AAAGCGAGCA AAAATCGAAG ATCCGAAGGA 60
CAACGTGTTC ATGGTGGAAA AAGTGCTGGA CAAGCGAACT GGAAAAGCCG GCAGAGACGA 120
ATTTCTCATA CAGTGGCAAG GATTCCCCGA GTCTGACTCT AGCTGGGAGC CGAGAGAGAA 180
TCTCCAGTGC GTCGAGATGT TGGACGAGTT TGAGAGGGAA TTTTCAAAGA GAGAGAAACC 240
AATTCGCAAA CGACACAGCC AGAAGCCCGA ACCTTCCGAA GATCAAGCGG ATCCAGAAGA 300
GGATAAAGAT GAAAAGAAGG AAACGAATCA AAATGACAAA TTCTCACTGG AAGGCAAGCA 360
GTTAAAATGC ATTGTCGGGC TCACCAAGGG ACCTGGGGAA CTTCATTTTC TGTGCAAATT 420
CAGTGATGAC ACGGCACGGC TTCTTCCAGC GAAGGAGGTG AACAGTCGCT ATCCGAGCCA 480
AGTTATCAGA TACTACGAAT CCAAGCTAAC AATCCAAGAC CCAAAAGCCG ACGAGCTTTA 540
ATCACTCCCC ACCCCGATAC ACGTGTTCAA TATCATGTTC TCTCATCTCA TTCCCATATT 600
CTTTTTGAAT TATCTTGTAA AATCTATACC AATTTTTGTG CTAACCCCTG AAATCGAGAC 660
TAAATATTAT TGAATCAATA AAAATTTCTT GAGACACA 699
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-1267--Proteomics identification
KW-1185--Reference proteome
--
Interpro

IPR000953--Chromo/shadow_dom
IPR017984--Chromo_dom_subgr
IPR023780--Chromo_domain
IPR008251--Chromo_shadow_dom
IPR016197--Chromodomain-like
PROSITE

PS50013--CHROMO_2
Pfam

PF00385--Chromo
PF01393--Chromo_shadow
Gene Ontology

GO:0000793--C:condensed chromosome
GO:0005720--C:nuclear heterochromatin
GO:0034399--C:nuclear periphery
GO:0005634--C:nucleus
GO:0016458--P:gene silencing
GO:0007281--P:germ cell development
GO:0008406--P:gonad development
GO:0046580--P:negative regulation of Ras protein signal transduction
GO:0040027--P:negative regulation of vulval development
GO:0002119--P:nematode larval development
GO:0040010--P:positive regulation of growth rate
GO:0045595--P:regulation of cell differentiation
GO:1900193--P:regulation of oocyte maturation
GO:0000003--P:reproduction
Orthology
WERAM ID Ensembl Protein ID Species Identity E-value Score
WERAM-Gam-0140 ENSGMOP00000014229.1 Gadus morhua 39 5e-21 97.4
WERAM-Orn-0050 ENSONIP00000005779.1 Oreochromis niloticus 39 2e-19 92.8
WERAM-Dar-0007 ENSDARP00000009789.7 Danio rerio 37 3e-19 91.7
WERAM-Drm-0034 FBpp0071221 Drosophila melanogaster 36 3e-19 91.7
WERAM-Bot-0058 ENSBTAP00000007283.4 Bos taurus 38 6e-19 90.9
WERAM-Xim-0006 ENSXMAP00000001021.1 Xiphophorus maculatus 36 2e-18 89.4
WERAM-Pof-0032 ENSPFOP00000002567.2 Poecilia formosa 36 2e-18 89.0
WERAM-Mup-0215 ENSMPUP00000018538.1 Mustela putorius furo 35 3e-18 88.6
WERAM-Sus-0215 ENSSSCP00000026206.1 Sus scrofa 36 4e-18 87.8
WERAM-Ptv-0001 ENSPVAP00000000296.1 Pteropus vampyrus 37 5e-18 87.4
WERAM-Poa-0044 ENSPPYP00000005247.2 Pongo abelii 37 5e-18 87.4
WERAM-Ten-0027 ENSTNIP00000005724.1 Tetraodon nigroviridis 38 5e-18 87.4
WERAM-Aim-0013 ENSAMEP00000000740.1 Ailuropoda melanoleuca 35 6e-18 87.4
WERAM-Ova-0173 ENSOARP00000017451.1 Ovis aries 35 6e-18 87.4
WERAM-Otg-0140 ENSOGAP00000012061.2 Otolemur garnettii 35 6e-18 87.4
WERAM-Sah-0103 ENSSHAP00000011342.1 Sarcophilus harrisii 38 6e-18 87.4
WERAM-Orla-0051 ENSORLP00000006270.1 Oryzias latipes 39 8e-18 87.0
WERAM-Cap-0091 ENSCPOP00000006971.2 Cavia porcellus 36 8e-18 87.0
WERAM-Anc-0142 ENSACAP00000013153.3 Anolis carolinensis 37 8e-18 87.0
WERAM-Xet-0081 ENSXETP00000026572.3 Xenopus tropicalis 37 1e-17 86.7
WERAM-Fec-0110 ENSFCAP00000009423.3 Felis catus 37 1e-17 86.7
WERAM-Caf-0078 ENSCAFP00000009868.3 Canis familiaris 37 1e-17 86.7
WERAM-Tub-0057 ENSTBEP00000007000.1 Tupaia belangeri 37 1e-17 86.7
WERAM-Paa-0083 ENSPANP00000000701.1 Papio anubis 37 1e-17 86.7
WERAM-Pat-0042 ENSPTRP00000008567.2 Pan troglodytes 37 1e-17 86.7
WERAM-Nol-0192 ENSNLEP00000021446.1 Nomascus leucogenys 37 1e-17 86.7
WERAM-Myl-0008 ENSMLUP00000000590.2 Myotis lucifugus 37 1e-17 86.7
WERAM-Mim-0051 ENSMICP00000004948.1 Microcebus murinus 37 1e-17 86.7
WERAM-Mam-0033 ENSMMUP00000006559.1 Macaca mulatta 37 1e-17 86.7
WERAM-Ict-0128 ENSSTOP00000013142.2 Ictidomys tridecemlineatus 37 1e-17 86.7
WERAM-Hos-0048 ENSP00000449207.1 Homo sapiens 37 1e-17 86.7
WERAM-Gog-0001 ENSGGOP00000000040.2 Gorilla gorilla 37 1e-17 86.7
WERAM-Eqc-0044 ENSECAP00000006177.1 Equus caballus 37 1e-17 86.7
WERAM-Chs-0059 ENSCSAP00000001750.1 Chlorocebus sabaeus 37 1e-17 86.7
WERAM-Caj-0199 ENSCJAP00000035012.1 Callithrix jacchus 37 1e-17 86.7
WERAM-Ect-0014 ENSETEP00000000985.1 Echinops telfairi 37 1e-17 86.3
WERAM-Dio-0098 ENSDORP00000009987.1 Dipodomys ordii 37 1e-17 86.3
WERAM-Prc-0021 ENSPCAP00000001721.1 Procavia capensis 37 1e-17 86.3
WERAM-Loa-0021 ENSLAFP00000001314.1 Loxodonta africana 37 1e-17 86.3
WERAM-Dan-0069 ENSDNOP00000007127.2 Dasypus novemcinctus 37 2e-17 85.9
WERAM-Ran-0184 ENSRNOP00000052163.2 Rattus norvegicus 37 2e-17 85.5
WERAM-Mum-0020 ENSMUSP00000104441.3 Mus musculus 37 2e-17 85.5
WERAM-Asm-0160 ENSAMXP00000015994.1 Astyanax mexicanus 37 2e-17 85.5
WERAM-Pes-0024 ENSPSIP00000004906.1 Pelodiscus sinensis 34 3e-17 85.1
WERAM-Gaa-0031 ENSGACP00000005142.1 Gasterosteus aculeatus 36 3e-17 85.1
WERAM-Tut-0053 ENSTTRP00000004253.1 Tursiops truncatus 36 3e-17 84.7
WERAM-Orc-0135 ENSOCUP00000011485.2 Oryctolagus cuniculus 37 4e-17 84.3
WERAM-Tar-0197 ENSTRUP00000040634.1 Takifugu rubripes 37 5e-17 84.3
WERAM-Pem-0038 ENSPMAP00000004890.1 Petromyzon marinus 34 6e-17 84.0
WERAM-Soa-0076 ENSSARP00000007237.1 Sorex araneus 34 7e-17 84.0
WERAM-Leo-0115 ENSLOCP00000014443.1 Lepisosteus oculatus 36 7e-17 84.0
WERAM-Tas-0030 ENSTSYP00000003062.1 Tarsius syrichta 36 9e-17 83.6
WERAM-Chh-0115 ENSCHOP00000012258.1 Choloepus hoffmanni 34 1e-16 83.2
WERAM-Mod-0004 ENSMODP00000000687.1 Monodelphis domestica 34 1e-16 83.2
WERAM-Ocp-0110 ENSOPRP00000010669.1 Ochotona princeps 34 1e-16 83.2
WERAM-Ora-0086 ENSOANP00000014578.2 Ornithorhynchus anatinus 34 2e-16 82.4
WERAM-Vip-0116 ENSVPAP00000010686.1 Vicugna pacos 37 2e-16 82.4
WERAM-Lac-0097 ENSLACP00000012217.1 Latimeria chalumnae 36 6e-16 80.9
WERAM-Tag-0045 ENSTGUP00000002967.1 Taeniopygia guttata 33 2e-15 79.3
WERAM-Meg-0109 ENSMGAP00000011085.1 Meleagris gallopavo 33 2e-15 79.3
WERAM-Anp-0098 ENSAPLP00000011741.1 Anas platyrhynchos 33 2e-15 79.3
WERAM-Gaga-0108 ENSGALP00000017958.3 Gallus gallus 33 2e-15 79.0
WERAM-Fia-0115 ENSFALP00000009927.1 Ficedula albicollis 33 2e-15 79.0
WERAM-Mae-0074 ENSMEUP00000007510.1 Macropus eugenii 36 3e-15 78.2
WERAM-Ere-0053 ENSEEUP00000004419.1 Erinaceus europaeus 39 2e-14 75.5
WERAM-Cii-0080 ENSCINP00000030026.1 Ciona intestinalis 33 4e-12 68.2
Created Date 25-Jun-2016