WERAM Information

Tag Content
WERAM ID WERAM-Hos-0013
Ensembl Protein ID ENSP00000419765.1
Uniprot Accession Q9H8M2; BRD9_HUMAN; A6NFY8; B4DMQ2; B4DR93; Q2XUS1; Q6UWU9; Q8IUS4; Q9H5Q5; Q9H7R9
Genbank Protein ID NP_001009877.2; NP_001304880.1; NP_076413.3
Protein Name Bromodomain-containing protein 9
Genbank Nucleotide ID NM_001009877.2; NM_001317951.1; NM_023924.4
Gene Name BRD9
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000028310.17 ENST00000467963.5 ENSP00000419765.1
ENSG00000028310.17 ENST00000483173.5 ENSP00000419845.1
ENSG00000028310.17 ENST00000489093.1 ENSP00000420722.1
Details
Type Family Domain Substrates AA References (PMIDs)
Ac_Reader Bromodomain Bromodomain H3 K 22464331; 25703523
Status Reviewed
Classification
Type Family E-value Score Start End
Ac_Reader Bromodomain 5.80e-19 70.2 160 223
Organism Homo sapiens
NCBI Taxa ID 9606
Functional Description
(View)		 May play a role in chromatin remodeling and regulation of transcription.
Domain Profile
  Ac_Reader Bromodomain
          BROMO.txt   8 pFrepvdpqleipdYydiikePmdLstikerleegnYsspeefvkDvrlifnNakaynenkssvq 72 
                        +F  pv   + +p Y  iik+Pmd+ t+k ++ +++Y+s++ef +D++l+++Na++yn++++ ++
  ENSP00000419765.1 160 FFAFPVTD-AIAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYY 223
                        6899****.8***************************************************9886 PP
Protein Sequence
(Fasta)		MGKKHKKHKA EWRSSYEDYA DKPLEKPLKL VLKVGGSEVT ELSGSGHDSS YYDDRSDHER 60
ERHKEKKKKK KKKSEKEKHL DDEERRKRKE EKKRKREREH CDTEGEADDF DPGKKVEVEP 120
PPDRPVRACR TQPAENESTP IQQLLEHFLR QLQRKDPHGF FAFPVTDAIA PGYSMIIKHP 180
MDFGTMKDKI VANEYKSVTE FKADFKLMCD NAMTYNRPDT VYYKLAKKIL HAGFKMMSKQ 240
AALLGNEDTA VEEPVPEVVP VQVETAKKSK KPSREVISCM FEPEGNACSL TDSTAEEHVL 300
ALVEHAADEA RDRINRFLPG GKMGYLKRNG DGSLLYSVVN TAEPDADEEE THPVDLSSLS 360
SKLLPGFTTL GFKDERRNKV TFLSSATTAL SMQNNSVFGD LKSDEMELLY SAYGDETGVQ 420
CALSLQEFVK DAGSYSKKVV DDLLDQITGG DHSRTLFQLK QRRNVPMKPP DEAKVGDTLG 480
DSSSSVLEFM SMKSYPDVSV DISMLSSLGK VKKELDPDDS HLNLDETTKL LQDLHEAQAE 540
RGGSRPSSNL SSLSNASERD QHHLGSPSRL SVGEQPDVTH DPYEFLQSPE PAASAKT 597
Nucleotide Sequence
(Fasta)		CTGCCGCGGC CCCGCCTCGC CCCGTTTCCG GCGCGGCCCA GCGAGCTCGG CAACCTCGGC 60
GCAGCGAGCG CGGGCGGCCA GCCAGGGCCA GGGGGCGGTG GCGGCCAAGG TCCGACCGGG 120
TGCCAGCTGT TCCCAGCCCC CGCCTCGGGC CCGCCGCCGG CGCCGCCATG GGCAAGAAGC 180
ACAAGAAGCA CAAGGCCGAG TGGCGCTCGT CCTACGAGGA TTATGCCGAC AAGCCCCTGG 240
AGAAGCCTCT AAAGCTAGTC CTGAAGGTCG GAGGAAGTGA AGTGACTGAA CTCTCAGGAT 300
CCGGCCACGA CTCCAGTTAC TATGATGACA GGTCAGACCA TGAGCGAGAG AGGCACAAAG 360
AAAAGAAAAA GAAGAAGAAG AAGAAGTCCG AGAAGGAGAA GCATCTGGAC GATGAGGAAA 420
GAAGGAAGCG AAAGGAAGAG AAGAAGCGGA AGCGAGAGAG GGAGCACTGT GACACGGAGG 480
GAGAGGCTGA CGACTTTGAT CCTGGGAAGA AGGTGGAGGT GGAGCCGCCC CCAGATCGGC 540
CAGTCCGAGC GTGCCGGACA CAGCCAGCCG AAAATGAGAG CACACCTATT CAGCAACTCC 600
TGGAACACTT CCTCCGCCAG CTTCAGAGAA AAGATCCCCA TGGATTTTTT GCTTTTCCTG 660
TCACGGATGC AATTGCTCCT GGATATTCAA TGATAATAAA ACATCCCATG GATTTTGGCA 720
CCATGAAAGA CAAAATTGTA GCTAATGAAT ACAAGTCAGT TACGGAATTT AAGGCAGATT 780
TCAAGCTGAT GTGTGATAAT GCAATGACAT ACAATAGGCC AGATACCGTG TACTACAAGT 840
TGGCGAAGAA GATCCTTCAC GCAGGCTTTA AGATGATGAG CAAACAGGCA GCTCTTTTGG 900
GCAATGAAGA TACAGCTGTT GAGGAACCTG TCCCTGAAGT TGTACCAGTA CAAGTAGAAA 960
CTGCCAAGAA ATCCAAAAAG CCGAGTAGAG AAGTTATCAG CTGCATGTTT GAGCCTGAAG 1020
GGAATGCCTG CAGCTTGACG GACAGTACCG CAGAGGAGCA CGTGCTGGCG CTGGTGGAGC 1080
ACGCAGCTGA CGAAGCTCGG GACAGGATCA ACCGGTTCCT CCCAGGCGGC AAGATGGGCT 1140
ATCTGAAGAG GAACGGGGAC GGGAGCCTGC TCTACAGCGT GGTCAACACG GCCGAGCCGG 1200
ACGCTGATGA GGAGGAGACC CACCCGGTGG ACTTGAGCTC GCTCTCCAGT AAGCTACTCC 1260
CAGGCTTCAC CACGCTGGGC TTCAAAGACG AGAGAAGAAA CAAAGTCACC TTTCTCTCCA 1320
GTGCCACTAC TGCGCTTTCG ATGCAGAATA ATTCAGTATT TGGCGACTTG AAGTCGGACG 1380
AGATGGAGCT GCTCTACTCA GCCTACGGAG ATGAGACAGG CGTGCAGTGT GCGCTGAGCC 1440
TGCAGGAGTT TGTGAAGGAT GCTGGGAGCT ACAGCAAGAA AGTGGTGGAC GACCTCCTGG 1500
ACCAGATCAC AGGCGGAGAC CACTCTAGGA CGCTCTTCCA GCTGAAGCAG AGAAGAAATG 1560
TTCCCATGAA GCCTCCAGAT GAAGCCAAGG TTGGGGACAC CCTAGGAGAC AGCAGCAGCT 1620
CTGTTCTGGA GTTCATGTCG ATGAAGTCCT ATCCCGACGT TTCTGTGGAT ATCTCCATGC 1680
TCAGCTCTCT GGGGAAGGTG AAGAAGGAGC TGGACCCTGA CGACAGCCAT TTGAACTTGG 1740
ATGAGACGAC GAAGCTCCTG CAGGACCTGC ACGAAGCACA GGCGGAGCGC GGCGGCTCTC 1800
GGCCGTCGTC CAACCTCAGC TCCCTGTCCA ACGCCTCCGA GAGGGACCAG CACCACCTGG 1860
GAAGCCCTTC TCGCCTGAGT GTCGGGGAGC AGCCAGACGT CACCCACGAC CCCTATGAGT 1920
TTCTTCAGTC TCCAGAGCCT GCGGCCTCTG CCAAGACCTA ACTCTAGACC ACCTTCAGCT 1980
CTTTTATTTT ATTTTTTTAG TTTTATTTTG CACGTGTAGA GTTTTTGTCA TCAGACAAGG 2040
ACTTTGATCC TGTCCCCTTT GGCATGCGGG AAGCAGCCGC GGGGAGGTAA TGAATTGTCT 2100
GTGGTATCAT GTCAGCAGAG TCTCCAAGCC CCACGAACCC TGAGGAGTGG AGTCAT 2157
Sequence Source Ensembl
Keyword

KW-0002--3D-structure
KW-0007--Acetylation
KW-0025--Alternative splicing
KW-0103--Bromodomain
KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0597--Phosphoprotein
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
--
Interpro

IPR001487--Bromodomain
IPR021900--DUF3512
PROSITE

PS50014--BROMODOMAIN_2
Pfam

PF00439--Bromodomain
PF12024--DUF3512
Gene Ontology

GO:0070577--F:lysine-acetylated histone binding
GO:0003676--F:nucleic acid binding
GO:0016568--P:chromatin modification
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated
Orthology
WERAM ID Ensembl Protein ID Species Identity E-value Score
WERAM-Chs-0204 ENSCSAP00000013448.1 Chlorocebus sabaeus 99 0.0 924
WERAM-Gog-0226 ENSGGOP00000028627.1 Gorilla gorilla 98 0.0 892
WERAM-Paa-0024 ENSPANP00000006332.1 Papio anubis 99 0.0 891
WERAM-Otg-0091 ENSOGAP00000007899.2 Otolemur garnettii 95 0.0 877
WERAM-Ran-0104 ENSRNOP00000021000.7 Rattus norvegicus 93 0.0 862
WERAM-Myl-0043 ENSMLUP00000003850.2 Myotis lucifugus 93 0.0 857
WERAM-Mum-0204 ENSMUSP00000096982.2 Mus musculus 92 0.0 852
WERAM-Poa-0136 ENSPPYP00000017101.1 Pongo abelii 96 0.0 847
WERAM-Bot-0072 ENSBTAP00000045723.3 Bos taurus 91 0.0 835
WERAM-Caf-0122 ENSCAFP00000015985.4 Canis familiaris 90 0.0 833
WERAM-Mam-0134 ENSMMUP00000019345.2 Macaca mulatta 94 0.0 832
WERAM-Pat-0136 ENSPTRP00000028621.5 Pan troglodytes 94 0.0 830
WERAM-Aim-0092 ENSAMEP00000008748.1 Ailuropoda melanoleuca 90 0.0 829
WERAM-Cap-0044 ENSCPOP00000003677.2 Cavia porcellus 93 0.0 820
WERAM-Fec-0104 ENSFCAP00000008843.3 Felis catus 89 0.0 817
WERAM-Nol-0116 ENSNLEP00000013308.1 Nomascus leucogenys 99 0.0 811
WERAM-Mup-0114 ENSMPUP00000010007.1 Mustela putorius furo 89 0.0 809
WERAM-Orc-0103 ENSOCUP00000008743.2 Oryctolagus cuniculus 90 0.0 803
WERAM-Meg-0016 ENSMGAP00000001389.2 Meleagris gallopavo 87 0.0 800
WERAM-Ora-0066 ENSOANP00000010046.4 Ornithorhynchus anatinus 89 0.0 791
WERAM-Sah-0092 ENSSHAP00000010784.1 Sarcophilus harrisii 89 0.0 791
WERAM-Mod-0007 ENSMODP00000000954.2 Monodelphis domestica 89 0.0 791
WERAM-Gaga-0115 ENSGALP00000020415.4 Gallus gallus 83 0.0 790
WERAM-Fia-0162 ENSFALP00000013817.1 Ficedula albicollis 88 0.0 786
WERAM-Caj-0043 ENSCJAP00000007069.2 Callithrix jacchus 90 0.0 778
WERAM-Eqc-0091 ENSECAP00000011046.1 Equus caballus 88 0.0 778
WERAM-Tag-0101 ENSTGUP00000006978.1 Taeniopygia guttata 87 0.0 777
WERAM-Anp-0083 ENSAPLP00000009753.1 Anas platyrhynchos 87 0.0 770
WERAM-Anc-0098 ENSACAP00000009199.2 Anolis carolinensis 87 0.0 763
WERAM-Ict-0188 ENSSTOP00000016314.1 Ictidomys tridecemlineatus 88 0.0 761
WERAM-Tut-0102 ENSTTRP00000008534.1 Tursiops truncatus 84 0.0 755
WERAM-Dan-0111 ENSDNOP00000013727.3 Dasypus novemcinctus 85 0.0 752
WERAM-Dio-0031 ENSDORP00000003260.1 Dipodomys ordii 84 0.0 715
WERAM-Mae-0041 ENSMEUP00000003755.1 Macropus eugenii 85 0.0 704
WERAM-Lac-0018 ENSLACP00000002817.1 Latimeria chalumnae 74 0.0 701
WERAM-Ect-0073 ENSETEP00000007999.1 Echinops telfairi 81 0.0 696
WERAM-Pes-0017 ENSPSIP00000004110.1 Pelodiscus sinensis 83 0.0 668
WERAM-Leo-0076 ENSLOCP00000009834.1 Lepisosteus oculatus 69 0.0 655
WERAM-Ova-0170 ENSOARP00000017152.1 Ovis aries 71 0.0 652
WERAM-Ptv-0009 ENSPVAP00000001336.1 Pteropus vampyrus 75 3e-177 619
WERAM-Tar-0173 ENSTRUP00000036328.1 Takifugu rubripes 69 2e-176 616
WERAM-Pof-0002 ENSPFOP00000000191.2 Poecilia formosa 68 7e-176 614
WERAM-Ten-0214 ENSTNIP00000021580.1 Tetraodon nigroviridis 69 1e-175 613
WERAM-Dar-0040 ENSDARP00000023970.6 Danio rerio 68 2e-175 613
WERAM-Xim-0174 ENSXMAP00000014105.1 Xiphophorus maculatus 67 2e-175 612
WERAM-Orla-0080 ENSORLP00000010152.3 Oryzias latipes 66 1e-174 610
WERAM-Orn-0030 ENSONIP00000003814.1 Oreochromis niloticus 66 2e-172 603
WERAM-Gam-0186 ENSGMOP00000018080.1 Gadus morhua 66 9e-168 587
WERAM-Xet-0089 ENSXETP00000028698.3 Xenopus tropicalis 66 5e-166 581
WERAM-Gaa-0085 ENSGACP00000011339.2 Gasterosteus aculeatus 66 2e-165 580
WERAM-Tub-0038 ENSTBEP00000004572.1 Tupaia belangeri 70 6e-161 565
WERAM-Loa-0032 ENSLAFP00000002159.3 Loxodonta africana 87 4e-160 562
WERAM-Tas-0012 ENSTSYP00000001436.1 Tarsius syrichta 60 5e-108 389
WERAM-Ocp-0079 ENSOPRP00000006857.2 Ochotona princeps 75 1e-80 298
WERAM-Pem-0045 ENSPMAP00000005437.1 Petromyzon marinus 40 8e-76 282
WERAM-Soa-0004 ENSSARP00000000368.1 Sorex araneus 83 3e-65 247
WERAM-Chh-0076 ENSCHOP00000008281.1 Choloepus hoffmanni 34 5e-59 226
WERAM-Sus-0148 ENSSSCP00000019491.1 Sus scrofa 33 1e-54 212
WERAM-Asm-0207 ENSAMXP00000019404.1 Astyanax mexicanus 32 9e-54 209
WERAM-Cii-0025 ENSCINP00000009862.3 Ciona intestinalis 34 1e-52 205
WERAM-Drm-0043 FBpp0079111 Drosophila melanogaster 29 5e-42 169
WERAM-Prc-0106 ENSPCAP00000009591.1 Procavia capensis 66 9e-41 166
WERAM-Vip-0021 ENSVPAP00000002042.1 Vicugna pacos 65 9e-40 162
WERAM-Cis-0073 ENSCSAVP00000015900.1 Ciona savignyi 58 4e-32 137
WERAM-Cae-0034 C01H6.7a.1 Caenorhabditis elegans 27 1e-25 115
WERAM-Ere-0101 ENSEEUP00000010459.1 Erinaceus europaeus 68 1e-22 105
WERAM-Zem-0032 GRMZM2G044044_P01 Zea mays 45 5e-20 97.1
WERAM-Php-0061 PP1S259_122V6.1 Physcomitrella patens 43 7e-20 96.7
WERAM-Tra-0090 Traes_2DS_3F067BAD4.1 Triticum aestivum 46 9e-20 96.3
WERAM-Aet-0035 EMT27625 Aegilops tauschii 46 1e-19 95.9
WERAM-Tru-0069 TRIUR3_26466-P1 Triticum urartu 46 1e-19 95.9
WERAM-Mua-0140 GSMUA_Achr9P11570_001 Musa acuminata 44 1e-19 95.5
WERAM-Sei-0099 Si028722m Setaria italica 44 4e-19 94.0
WERAM-Prp-0036 EMJ02406 Prunus persica 46 6e-19 93.6
WERAM-Sol-0075 Solyc06g051210.2.1 Solanum lycopersicum 48 6e-19 93.2
WERAM-Viv-0118 VIT_18s0122g01220.t01 Vitis vinifera 47 1e-18 92.4
WERAM-Orbr-0086 OB07G21800.1 Oryza brachyantha 46 1e-18 92.4
WERAM-Orni-0075 ONIVA07G14220.1 Oryza nivara 43 1e-18 92.4
WERAM-Org-0077 ORGLA07G0130400.1 Oryza glaberrima 43 1e-18 92.4
WERAM-Orb-0077 OBART07G15930.1 Oryza barthii 43 1e-18 92.4
WERAM-Ori-0086 BGIOSGA025787-PA Oryza indica 43 1e-18 92.4
WERAM-Orm-0072 OMERI07G12350.1 Oryza meridionalis 43 1e-18 92.0
WERAM-Orgl-0074 OGLUM07G15680.1 Oryza glumaepatula 46 1e-18 92.0
WERAM-Orp-0074 OPUNC07G14740.1 Oryza punctata 46 1e-18 92.0
WERAM-Amt-0042 ERN17379 Amborella trichopoda 46 2e-18 92.0
WERAM-Glm-0096 GLYMA08G43053.1 Glycine max 33 3e-18 90.9
WERAM-Spr-0041 CBQ70925 Sporisorium reilianum 42 5e-18 90.5
WERAM-Pot-0050 POPTR_0004s21620.1 Populus trichocarpa 45 5e-18 90.5
WERAM-Brd-0013 BRADI1G26420.1 Brachypodium distachyon 43 5e-18 90.5
WERAM-Met-0062 AES70383 Medicago truncatula 41 1e-17 89.0
WERAM-Art-0142 AT5G55040.2 Arabidopsis thaliana 42 1e-17 89.0
WERAM-Arl-0110 fgenesh2_kg.8__ 1402__ AT5G55040.2 Arabidopsis lyrata 42 1e-17 89.0
WERAM-Usm-0035 UM05887P0 Ustilago maydis 41 2e-17 88.6
WERAM-Sot-0044 PGSC0003DMT400040444 Solanum tuberosum 46 2e-17 88.6
WERAM-Thc-0025 EOX98890 Theobroma cacao 41 5e-17 87.0
WERAM-Sob-0034 Sb02g034450.1 Sorghum bicolor 38 6e-17 86.7
WERAM-Mim-0029 ENSMICP00000002767.1 Microcebus murinus 45 7e-17 86.3
WERAM-Orr-0029 ORUFI03G02210.1 Oryza rufipogon 41 1e-16 85.9
WERAM-Orl-0024 KN538737.1_FGP053 Oryza longistaminata 41 1e-16 85.9
WERAM-Lep-0103 LPERR09G14620.1 Leersia perrieri 43 1e-16 85.9
WERAM-Bro-0125 Bo7g061450.1 Brassica oleracea 43 1e-16 85.5
WERAM-Ors-0027 OS03T0130800-01 Oryza sativa 41 2e-16 85.1
WERAM-Brr-0126 Bra025837.1-P Brassica rapa 43 2e-16 84.7
Created Date 25-Jun-2016