WERAM Information

Tag Content
WERAM ID WERAM-Hos-0218
Ensembl Protein ID ENSP00000397911.2
Uniprot Accession Q9H930; SP14L_HUMAN; Q2M375; Q4ZG65; Q9BSP3
Genbank Protein ID NP_001295091.1; NP_001295092.1; NP_612411.4; XP_006712918.1
Protein Name Nuclear body protein SP140-like protein
Genbank Nucleotide ID NM_001308162.1; NM_001308163.1; NM_138402.4; XM_006712855.1
Gene Name SP140L
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000185404.16 ENST00000415673.6 ENSP00000397911.2
ENSG00000185404.16 ENST00000243810.10 ENSP00000243810.7
ENSG00000185404.16 ENST00000396563.8 ENSP00000379811.5
Details
Type Family Domain Substrates AA References (PMIDs)
Ac_Reader Bromodomain Bromodomain K 25593309
Status Reviewed
Classification
Type Family E-value Score Start End
Ac_Reader Bromodomain 2.00e-19 71.7 484 554
Organism Homo sapiens
NCBI Taxa ID 9606
Functional Description
(View)
Domain Profile
  Ac_Reader Bromodomain
          BROMO.txt   1 kehevsepFrepvdpqleipdYydi......ikePmdLstikerleegnYsspeefvkDvrlifnNakaynenkssvq 72 
                        +++++s++F       ++ip+Yy+i      +kePm+L++ik+rl+e+ Y ++e fv+D+rlif+N++a +++k+++q
  ENSP00000397911.2 484 YCCSESSFF-------AKIPYYYYIreacqgLKEPMWLDKIKKRLNEHGYPQVEGFVQDMRLIFQNHRASYKYKDFGQ 554
                        566666666.......4677******************************************************9986 PP
Protein Sequence
(Fasta)		MAGGGSDLST RGLNGGVSQV ANEMNHLPAH SQSLQRLFTE DQDVDEGLVY DTVFKHFKRH 60
KLEISNAIKK TFPFLEGLRD RELITNKMFE DSEDSCRNLV PVQRVVYNVL SELEKTFNLS 120
VLEALFSEVN MQEYPDLIHI YKSFKNAIQD KLSFQESDRK EREERPDIKL SLKQGEVPES 180
PEARKESDQA CGKMDTVDIA NNSTLGKPKR KRRKKKGHGW SRMGTRTQKN NQQNDNSKAD 240
GQLVSSEKKA NMNLKDLSKI RGRKRGKPGT HFTQSDRAPQ KRVRSRASRK HKDETVDFQA 300
PLLPVTCGGV KGILHKEKLE QGTLAKCIQT EDGKWFTPME FEIKGGYARS KNWRLSVRCG 360
GWPLRRLMEE GSLPNPPRIY YRNKKRILKS QNNSSVDPCM RNLDECEVCR DGGELFCCDT 420
CSRVFHEDCH IPPVESEKTP WNCIFCRMKE SPGSQQCCQE SEVLERQMCP EEQLKCEFLL 480
LKVYCCSESS FFAKIPYYYY IREACQGLKE PMWLDKIKKR LNEHGYPQVE GFVQDMRLIF 540
QNHRASYKYK DFGQMGLRLE AEFEKDFKEV FAIQETNGNS
Nucleotide Sequence
(Fasta)		AGGGCAGCCA CACTGCACGC AGGCTGGGCC GACTGGGGAG CTCATAGGCC AGGCTCTGAC 60
ACCCAGGCAG GGCCTAGGGT GGGACGATGG CAGGTGGGGG CAGCGACCTG AGCACCAGGG 120
GGCTGAACGG AGGTGTTTCA CAAGTAGCAA ATGAGATGAA CCATCTTCCT GCACACAGCC 180
AAAGTCTGCA AAGGCTGTTC ACGGAAGACC AGGATGTAGA TGAGGGACTT GTCTATGACA 240
CTGTATTCAA GCACTTCAAA AGACATAAGC TGGAGATATC AAATGCAATA AAAAAGACAT 300
TTCCATTCCT TGAGGGCCTC CGCGATCGGG AACTCATCAC AAATAAAATG TTTGAAGATT 360
CTGAAGATTC TTGTAGAAAC CTGGTCCCTG TACAAAGAGT GGTGTACAAT GTTCTCAGTG 420
AACTGGAGAA GACATTTAAC CTGTCAGTTT TGGAAGCACT GTTCAGCGAG GTCAACATGC 480
AGGAATACCC CGATTTAATT CACATTTATA AAAGCTTCAA AAATGCAATC CAAGACAAAT 540
TGTCTTTCCA AGAAAGTGAT CGAAAAGAAA GGGAAGAGAG GCCTGACATC AAACTAAGTC 600
TTAAACAAGG AGAAGTGCCA GAAAGCCCGG AAGCAAGGAA GGAAAGTGAC CAAGCATGTG 660
GCAAAATGGA TACTGTGGAT ATTGCAAACA ACTCTACTTT GGGAAAACCC AAGAGGAAAA 720
GAAGAAAAAA GAAGGGGCAT GGCTGGAGCA GAATGGGAAC GAGAACGCAG AAAAACAACC 780
AACAAAATGA TAACAGCAAA GCCGATGGCC AGCTGGTCTC GAGTGAAAAG AAGGCGAACA 840
TGAATCTGAA AGACCTTTCC AAGATTAGGG GGAGAAAGAG AGGCAAACCT GGAACCCACT 900
TTACTCAGAG TGACAGAGCT CCACAGAAAA GAGTCCGATC AAGAGCTTCA AGAAAGCACA 960
AAGATGAAAC TGTGGATTTT CAGGCTCCTT TACTTCCAGT GACCTGTGGT GGGGTGAAGG 1020
GAATTTTACA TAAGGAGAAA TTGGAACAAG GAACCTTGGC AAAGTGTATA CAGACTGAGG 1080
ATGGAAAATG GTTCACCCCC ATGGAATTTG AAATCAAAGG AGGCTACGCA AGATCAAAGA 1140
ACTGGAGGCT GAGTGTGCGC TGTGGCGGGT GGCCCCTACG ACGGCTGATG GAGGAAGGAT 1200
CTCTACCTAA TCCTCCAAGA ATATATTACA GGAACAAAAA GAGAATACTG AAGTCTCAAA 1260
ACAATAGCTC AGTTGACCCT TGTATGAGAA ACTTGGATGA GTGTGAGGTG TGCCGGGACG 1320
GAGGGGAGCT GTTCTGTTGC GACACTTGTT CAAGAGTCTT CCATGAGGAC TGCCACATCC 1380
CACCTGTGGA AAGTGAGAAG ACCCCGTGGA ATTGCATCTT CTGCAGGATG AAGGAGTCTC 1440
CGGGAAGCCA ACAGTGTTGT CAGGAATCTG AGGTCCTGGA GAGGCAGATG TGTCCTGAGG 1500
AACAGTTGAA ATGTGAGTTC CTCCTCTTGA AAGTCTATTG CTGTTCTGAG AGCTCCTTTT 1560
TTGCCAAGAT TCCATACTAT TATTATATTA GAGAGGCGTG TCAAGGCCTG AAGGAGCCCA 1620
TGTGGTTGGA TAAAATCAAG AAAAGGCTGA ATGAGCACGG TTACCCCCAA GTGGAGGGGT 1680
TTGTACAAGA CATGCGCCTC ATCTTCCAGA ACCACAGGGC CTCTTACAAG TATAAGGATT 1740
TTGGCCAAAT GGGACTTAGA CTGGAGGCTG AATTTGAGAA GGATTTCAAG GAAGTGTTTG 1800
CTATTCAGGA AACAAATGGG AACAGTTGAC TGGTTTAGTG GATGCTGAAG GCCTTCAGGA 1860
AATATGCTAC TGGTTGCCAC TGACTTCAAA CTGAGAGCAC TTGGGAAATA GCACATGCAG 1920
GGAGAGGCTT TTCTCTGAGC CTCCCTCATC TGCCCAAAAA CAAATCCTCA AAAGAAATTT 1980
GATCATCATG AATCCCATCC CCAAGAATCT CATCAACCAG GGAAGAGGAA CTGAGATCAC 2040
AGGGAAGGAG ATTGGAGGTG ATACCAGCAC AGACAGACTC TCACCTCTTC TCCTGAGGTC 2100
TGCTCCAGAC AACATTTATT ACTCACAAGA CCTTTTTCCT CCGTTTTTTT TTTGAGATGG 2160
AGTCTCACAC AGTCACCCGG GATTGGAATG CAATGGCGCG ATCTCAGCTC ACTGCAACCT 2220
CTGCCTCCCG GATTCAAGTG ATTCTCCTGT CTCAGCCTCC CAAGTAGCTG GGATTACAGT 2280
GCCTGCCACC ATGCCCAGCT AATTTTTTGC ATTTTTAGTA GAGACGGGGT TTCACTATGT 2340
TGGCCAGGCT GGTCTCGAAC TCCTGACCTC ATGAGCCGCC CGCCTTGGCC TCCCAAAGTG 2400
CTGGGACGTG ACAGGAGTGA GCCACCACAC CTGGCCACTC GCAAGACCTT TTATCTGAAA 2460
ACCAGCCAAG CTTTATTCAC GACACACTTC TTCCCTTCAC TCTCCCACTT CTGTGGTCAA 2520
CTCCCTGCAG AACTCCCAAA CTGCCGTTCT TTTCGATAGC TCACGATGGT GTATGAGTGT 2580
CAATCATCTG ACCCTTCTTG GAGTCTCATA TTTCGTGGAA CTCCTGTGCA AACATATATT 2640
ATTAAATTTT TTTTCCTCCT GTCAA 2666
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger
--
Interpro

IPR001487--Bromodomain
IPR004865--HSR_dom
IPR000770--SAND_dom
IPR010919--SAND_dom-like
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS50014--BROMODOMAIN_2
PS51414--HSR
PS50864--SAND
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2
Pfam

PF00439--Bromodomain
PF00628--PHD
PF01342--SAND
PF03172--Sp100
Gene Ontology

GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0008270--F:zinc ion binding
Orthology
WERAM ID Ensembl Protein ID Species Identity E-value Score
WERAM-Pat-0102 ENSPTRP00000022251.4 Pan troglodytes 98 0.0 1169
WERAM-Gog-0031 ENSGGOP00000002852.2 Gorilla gorilla 98 0.0 1159
WERAM-Chs-0080 ENSCSAP00000003145.1 Chlorocebus sabaeus 84 0.0 995
WERAM-Caj-0238 ENSCJAP00000024464.2 Callithrix jacchus 82 0.0 964
WERAM-Mam-0102 ENSMMUP00000015993.2 Macaca mulatta 87 0.0 708
WERAM-Poa-0114 ENSPPYP00000014816.1 Pongo abelii 87 0.0 706
WERAM-Caf-0118 ENSCAFP00000015760.3 Canis familiaris 61 0.0 660
WERAM-Paa-0172 ENSPANP00000006222.1 Papio anubis 79 0.0 639
WERAM-Aim-0187 ENSAMEP00000017451.1 Ailuropoda melanoleuca 68 4e-159 558
WERAM-Mim-0141 ENSMICP00000014357.1 Microcebus murinus 70 1e-158 557
WERAM-Eqc-0184 ENSECAP00000019711.1 Equus caballus 53 4e-154 542
WERAM-Tut-0106 ENSTTRP00000008817.1 Tursiops truncatus 67 4e-153 538
WERAM-Fec-0029 ENSFCAP00000002319.3 Felis catus 68 6e-152 535
WERAM-Loa-0030 ENSLAFP00000001920.4 Loxodonta africana 69 3e-151 532
WERAM-Sus-0120 ENSSSCP00000017226.2 Sus scrofa 66 4e-149 525
WERAM-Ova-0216 ENSOARP00000022188.1 Ovis aries 59 9e-146 514
WERAM-Otg-0206 ENSOGAP00000020888.1 Otolemur garnettii 64 3e-138 489
WERAM-Mup-0049 ENSMPUP00000004382.1 Mustela putorius furo 62 2e-136 483
WERAM-Mum-0221 ENSMUSP00000079095.4 Mus musculus 45 4e-135 479
WERAM-Ict-0054 ENSSTOP00000004707.2 Ictidomys tridecemlineatus 62 4e-134 476
WERAM-Ptv-0050 ENSPVAP00000005420.1 Pteropus vampyrus 59 8e-130 461
WERAM-Cap-0119 ENSCPOP00000009466.2 Cavia porcellus 58 9e-121 431
WERAM-Prc-0057 ENSPCAP00000005387.1 Procavia capensis 66 2e-117 420
WERAM-Myl-0020 ENSMLUP00000001755.2 Myotis lucifugus 57 7e-115 412
WERAM-Ran-0148 ENSRNOP00000031057.6 Rattus norvegicus 53 4e-110 395
WERAM-Nol-0155 ENSNLEP00000016673.1 Nomascus leucogenys 54 3e-109 393
WERAM-Tas-0089 ENSTSYP00000009104.1 Tarsius syrichta 50 1e-107 388
WERAM-Dan-0044 ENSDNOP00000004457.3 Dasypus novemcinctus 49 2e-101 367
WERAM-Bot-0222 ENSBTAP00000054823.1 Bos taurus 74 2e-83 307
WERAM-Tub-0049 ENSTBEP00000005765.1 Tupaia belangeri 43 2e-81 301
WERAM-Ere-0052 ENSEEUP00000004410.1 Erinaceus europaeus 47 3e-73 273
WERAM-Vip-0071 ENSVPAP00000006559.1 Vicugna pacos 47 1e-72 271
WERAM-Ocp-0089 ENSOPRP00000007990.1 Ochotona princeps 53 2e-70 264
WERAM-Sah-0029 ENSSHAP00000003206.1 Sarcophilus harrisii 48 4e-59 226
WERAM-Lac-0066 ENSLACP00000008975.1 Latimeria chalumnae 39 4e-49 193
WERAM-Mod-0208 ENSMODP00000038934.1 Monodelphis domestica 38 2e-42 171
WERAM-Ect-0021 ENSETEP00000001537.1 Echinops telfairi 67 8e-38 155
WERAM-Ora-0139 ENSOANP00000030270.1 Ornithorhynchus anatinus 49 5e-37 153
WERAM-Dar-0193 ENSDARP00000108373.1 Danio rerio 34 2e-36 151
WERAM-Soa-0030 ENSSARP00000003044.1 Sorex araneus 44 2e-34 144
WERAM-Leo-0114 ENSLOCP00000014415.1 Lepisosteus oculatus 37 9e-32 135
WERAM-Pof-0069 ENSPFOP00000006195.2 Poecilia formosa 34 6e-31 133
WERAM-Orn-0097 ENSONIP00000010786.1 Oreochromis niloticus 31 2e-27 121
WERAM-Tar-0059 ENSTRUP00000012635.1 Takifugu rubripes 38 1e-24 112
WERAM-Ten-0081 ENSTNIP00000009576.1 Tetraodon nigroviridis 37 7e-24 109
WERAM-Xim-0010 ENSXMAP00000001247.1 Xiphophorus maculatus 30 2e-23 108
WERAM-Meg-0128 ENSMGAP00000013880.2 Meleagris gallopavo 39 2e-23 107
WERAM-Tag-0017 ENSTGUP00000001056.1 Taeniopygia guttata 35 3e-23 107
WERAM-Dio-0037 ENSDORP00000004316.1 Dipodomys ordii 38 4e-23 107
WERAM-Anp-0085 ENSAPLP00000010241.1 Anas platyrhynchos 30 4e-23 107
WERAM-Gaa-0204 ENSGACP00000025078.1 Gasterosteus aculeatus 39 5e-23 107
WERAM-Pes-0149 ENSPSIP00000017710.1 Pelodiscus sinensis 39 9e-23 105
WERAM-Orc-0070 ENSOCUP00000006290.2 Oryctolagus cuniculus 38 1e-22 105
WERAM-Gaga-0120 ENSGALP00000020886.4 Gallus gallus 39 1e-22 105
WERAM-Xet-0078 ENSXETP00000025313.3 Xenopus tropicalis 35 2e-22 105
WERAM-Fia-0050 ENSFALP00000003601.1 Ficedula albicollis 29 2e-22 104
WERAM-Gam-0174 ENSGMOP00000017205.1 Gadus morhua 35 2e-21 101
WERAM-Anc-0023 ENSACAP00000002604.2 Anolis carolinensis 30 2e-21 101
WERAM-Asm-0192 ENSAMXP00000018335.1 Astyanax mexicanus 34 2e-21 101
WERAM-Orla-0118 ENSORLP00000014098.1 Oryzias latipes 36 6e-21 100
WERAM-Chh-0017 ENSCHOP00000001525.1 Choloepus hoffmanni 30 5e-20 97.1
WERAM-Drm-0020 FBpp0083320 Drosophila melanogaster 35 2e-18 91.3
WERAM-Cii-0027 ENSCINP00000010542.3 Ciona intestinalis 37 8e-18 89.4
Created Date 25-Jun-2016