WERAM Information


Tag Content
WERAM ID WERAM-Hos-0179
Ensembl Protein ID ENSP00000362372.4
Uniprot Accession Q6RI45; BRWD3_HUMAN; C9IZ39; C9J3F3; Q2T9J6; Q5JRN1; Q6RI37; Q6RI42; Q6RI44; Q8N916
Genbank Protein ID NP_694984.4; XP_011529205.1; XP_011529206.1
Protein Name Bromodomain and WD repeat-containing protein 3
Genbank Nucleotide ID NM_153252.4; XM_011530903.1; XM_011530904.1
Gene Name BRWD3;BRODL
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000165288.10 ENST00000373275.4 ENSP00000362372.4
Details
Type Family Domain Substrates AA References (PMIDs)
Ac_Reader Bromodomain Bromodomain K 22464331
Status Reviewed
Classification
Type Family E-value Score Start End
Ac_Reader Bromodomain 1.60e-48 164.9 1161 1412
Organism Homo sapiens
NCBI Taxa ID 9606
Functional Description
(View)
Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape.
Domain Profile
  Ac_Reader Bromodomain

          BROMO.txt    4 evsepFrepvdpqleipdYydiikePmdLstikerleegnYsspeefvkDvrlifnNakaynenkssv 71  
++++pF pvd+ +p Y++++ P dL+ti++rle++ Y++++ ++ vr i +Na+++ne++s +
ENSP00000362372.4 1161 DFASPFAVPVDL-SAYPLYCTVVAYPTDLNTIRRRLENRFYRRISALMWEVRYIEHNARTFNEPDSPI 1227
5789********.7**************************************************9976 PP
BROMO.txt 1 kehevsepFrepvdpqleip.........................dYydiikePmdLstikerleegnYsspeefvkDvrlifnNakayn 65
+e+e+sepFr+p+d+ l++p dY+d+i++P+d+st+ke+le+gnY+sp+ef+kDvr+ifnN+kay+
ENSP00000362372.4 1317 YEREDSEPFRQPADL-LSYPghqeqegessesvvperqqdsslseDYQDVIDTPVDFSTVKETLEAGNYGSPLEFYKDVRQIFNNSKAYT 1405
79*************.9************************************************************************* PP
BROMO.txt 66 enkssvq 72
+nk+s++
ENSP00000362372.4 1406 SNKKSRI 1412
****986 PP

Protein Sequence
(Fasta)
MAAAPTQIEA ELYYLIARFL QSGPCNKSAQ VLVQELEEHQ LIPRRLDWEG KEHRRSFEDL 60
VAANAHIPPD YLLKICERIG PLLDKEIPQS VPGVQTLLGV GRQSLLRDAK DCKSTLWNGS 120
AFAALHRGRP PELPVNYVKP PNVVNITSAR QLTGCSRFGH IFPSSAYQHI KMHKRILGHL 180
SSVYCVAFDR SGRRIFTGSD DCLVKIWATD DGRLLATLRG HSAEISDMAV NYENTLIAAG 240
SCDKVVRVWC LRTCAPVAVL QGHSASITSI QFCPSTKGTN RYLTSTGADG TICFWQWHVK 300
TMKFRDRPVK FTERSRPGVQ ISCSSFSSGG MFITTGSTDH VIRIYYLGSE VPEKIAELES 360
HTDKVVAVQF CNNGDSLRFV SGSRDGTARI WQYQQQEWKS IVLDMATKMT GNNLPSGEDK 420
ITKLKVTMVA WDRYDTTVIT AVNNFLLKVW NSITGQLLHT LSGHDDEVFV LEAHPFDQRI 480
ILSAGHDGNI FIWDLDRGTK IRNYFNMIEG QGHGAVFDCK FSPDGNHFAC TDSHGHLLLF 540
GFGCSKYYEK IPDQMFFHTD YRPLIRDANN YVLDEQTQQA PHLMPPPFLV DVDGNPHPTK 600
FQRLVPGREN CKDEQLIPQL GYVANGDGEV VEQVIGQQTN DQDESILDGI IRELQREQDL 660
RLINEGDVPH LPVNRAYSVN GALRSPNMDI SSSPNIRLRR HSSQIEGVRQ MHNNAPRSQM 720
ATERDLMAWS RRVVVNELNN GVSRVQEECR TAKGDIEISL YTVEKKKKPS YTTQRNDYEP 780
SCGRSLRRTQ RKRQHTYQTR SNIEHNSQAS CQNSGVQEDS DSSSEEDETV GTSDASVEDP 840
VVEWQSESSS SDSSSEYSDW TADAGINLQP PKRQTRQTTR KICSSSDEEN LKSLEERQKK 900
PKQTRKKKGG LVSIAGEPNE EWFAPQWILD TIPRRSPFVP QMGDELIYFR QGHEAYVRAV 960
RKSKIYSVNL QKQPWNKMDL REQEFVKIVG IKYEVGPPTL CCLKLAFLDP ISGKMTGESF 1020
SIKYHDMPDV IDFLVLHQFY NEAKERNWQI GDRFRSIIDD AWWFGTVESQ QPFQPEYPDS 1080
SFQCYSVHWD NNEREKMSPW DMEPIPEGTA FPDEVGAGVP VSQEELTALL YKPQEGEWGA 1140
HSRDEECERV IQGINHLLSL DFASPFAVPV DLSAYPLYCT VVAYPTDLNT IRRRLENRFY 1200
RRISALMWEV RYIEHNARTF NEPDSPIVKA AKIVTDVLLR FIGDQSCTDI LDTYNKIKAE 1260
ERNSTDAEED TEIVDLDSDG PGTSSGRKVK CRGRRQSLKC NPDAWKKQCK ELLSLIYERE 1320
DSEPFRQPAD LLSYPGHQEQ EGESSESVVP ERQQDSSLSE DYQDVIDTPV DFSTVKETLE 1380
AGNYGSPLEF YKDVRQIFNN SKAYTSNKKS RIYSMMLRLS ALFESHIKNI ISEYKSAIQS 1440
QKRRRPRYRK RLRSSSSSLS SSGAPSPKGK QKQMKLQPKN DQNTSVSHAR TSSPFSSPVS 1500
DAAEGLSLYL LDDEPDGPFS SSSFGGYSRS GNSHDPGKAK SFRNRVLPVK QDHSLDGPLT 1560
NGDGREPRTG IKRKLLSASE EDENMGGEDK EKKETKEKSH LSTSESGELG SSLSSESTCG 1620
SDSDSESTSR TDQDYVDGDH DYSKFIQTRP KRKLRKQHGN GKRNWKTRGT GGRGRWGRWG 1680
RWSRGGRGRG GRGRGSRGRG GGGTRGRGRG RGGRGASRGA TRAKRARIAD DEFDTMFSGR 1740
FSRLPRIKTR NQGRRTVLYN DDSDNDNFVS TEDPLNLGTS RSGRVRKMTE KARVSHLMGW 1800
NY 1802
Nucleotide Sequence
(Fasta)
CTCTCCTTCC TCCTCCGCCT CCTCAGCTCT TGGGCTAGAA TATCTATGGG TCGAAACGTG 60
ATGCGATGAA TTCGAGAGAG AGCGAAACTA GGACGAGGAG TGCGGCGGAA GCGGCGGGAC 120
TCCCGGGCAT GGGGGCTTCA CCACAATAGA GGCAGCGCCC CCACCCGCCC CCGCCAGCCC 180
CTCCGGAGCG AAGCCCCCAA ACCCCCTCGG GAAAAGGATG GCGGCAGCAC CTACCCAGAT 240
CGAAGCCGAG CTGTATTACC TGATCGCTAG GTTCTTGCAG TCTGGACCCT GCAACAAATC 300
CGCTCAGGTG CTAGTGCAGG AGCTCGAGGA GCATCAGCTG ATTCCGCGCC GCTTAGATTG 360
GGAGGGGAAA GAGCACCGAA GAAGCTTCGA GGATCTGGTG GCAGCAAATG CACACATTCC 420
TCCAGACTAC CTCCTTAAAA TTTGTGAGAG AATTGGTCCT TTACTAGATA AAGAGATCCC 480
TCAGAGTGTT CCTGGGGTAC AGACATTATT AGGTGTTGGT CGGCAGTCTC TGCTACGGGA 540
TGCCAAAGAC TGTAAGAGTA CACTATGGAA TGGGTCTGCT TTTGCGGCTC TGCATAGAGG 600
CAGACCTCCA GAACTACCTG TAAATTATGT GAAACCTCCA AATGTGGTGA ATATCACCTC 660
TGCCAGGCAA TTAACCGGCT GTAGTCGCTT TGGTCATATT TTCCCTTCAT CTGCTTACCA 720
GCACATTAAG ATGCATAAGA GAATTCTGGG GCACTTGTCA TCTGTCTACT GTGTAGCATT 780
TGACCGAAGC GGGAGAAGAA TTTTTACAGG TTCAGATGAC TGTTTAGTAA AAATTTGGGC 840
TACAGATGAT GGACGCCTTC TTGCTACACT TCGTGGACAC TCTGCTGAAA TTTCTGACAT 900
GGCTGTTAAC TATGAAAACA CTCTTATTGC TGCAGGCAGC TGTGATAAGG TAGTAAGAGT 960
ATGGTGTCTT CGAACTTGTG CACCCGTTGC AGTCCTTCAG GGCCATTCAG CTTCTATTAC 1020
TTCCATACAG TTTTGTCCAT CAACTAAAGG CACAAACAGA TACCTCACTT CTACTGGTGC 1080
TGATGGAACA ATCTGTTTCT GGCAATGGCA TGTAAAAACA ATGAAGTTTA GAGATCGCCC 1140
GGTGAAATTT ACTGAGAGAT CCAGACCTGG AGTCCAGATA TCTTGTTCAT CTTTCAGTTC 1200
TGGTGGTATG TTCATTACAA CTGGTAGTAC TGACCATGTG ATTAGAATAT ATTATTTGGG 1260
TTCTGAGGTT CCTGAGAAAA TTGCTGAATT AGAGTCACAT ACGGATAAAG TTGTTGCTGT 1320
TCAGTTCTGT AACAATGGAG ACAGTTTAAG ATTTGTTAGT GGAAGTCGAG ATGGAACGGC 1380
AAGAATTTGG CAGTATCAGC AACAAGAATG GAAGAGTATA GTGCTAGACA TGGCTACTAA 1440
AATGACTGGC AATAATTTGC CATCTGGAGA AGACAAGATC ACTAAACTTA AGGTGACTAT 1500
GGTGGCCTGG GATCGCTATG ATACCACAGT TATTACTGCA GTGAACAATT TTCTTTTGAA 1560
AGTGTGGAAT TCTATCACAG GACAGCTTCT TCATACATTA TCTGGACATG ATGATGAAGT 1620
ATTCGTTCTA GAAGCCCATC CATTTGATCA AAGGATCATA CTTTCAGCAG GTCATGATGG 1680
GAACATTTTT ATTTGGGACC TTGACCGGGG GACCAAAATT CGGAATTACT TTAACATGAT 1740
TGAAGGCCAA GGCCATGGTG CGGTGTTTGA TTGTAAATTT TCACCAGATG GAAACCATTT 1800
TGCCTGCACA GATTCTCATG GACATTTGCT GCTTTTTGGT TTTGGATGCA GTAAATACTA 1860
CGAAAAGATT CCAGATCAGA TGTTCTTCCA CACGGATTAT CGTCCTCTTA TTCGTGATGC 1920
CAATAACTAT GTATTGGATG AACAAACCCA ACAAGCTCCT CACCTCATGC CTCCTCCATT 1980
TTTGGTGGAT GTTGATGGAA ATCCTCATCC CACAAAATTC CAACGGTTGG TACCAGGACG 2040
GGAAAATTGT AAAGATGAAC AGCTTATACC ACAGCTGGGA TATGTGGCTA ATGGTGATGG 2100
TGAGGTAGTA GAACAGGTAA TTGGGCAGCA AACCAATGAC CAAGATGAGA GCATTCTTGA 2160
TGGAATAATC AGGGAGCTGC AGAGAGAACA AGACCTGAGA CTAATTAATG AAGGAGATGT 2220
TCCACATTTA CCAGTTAATA GAGCATACTC TGTTAATGGT GCTCTGAGAA GTCCAAACAT 2280
GGACATATCT TCTTCCCCAA ACATCAGGCT TCGAAGACAT AGTAGTCAAA TTGAAGGTGT 2340
TAGACAAATG CATAACAATG CTCCTCGGAG CCAGATGGCC ACTGAAAGAG ATCTCATGGC 2400
GTGGAGCAGA AGAGTGGTGG TCAATGAACT AAATAATGGG GTTAGTAGGG TACAGGAAGA 2460
ATGTCGAACT GCAAAAGGTG ACATAGAAAT CAGTCTTTAT ACAGTTGAAA AGAAGAAAAA 2520
GCCATCTTAC ACTACTCAAA GGAATGATTA TGAGCCTAGC TGTGGGCGTT CTTTACGCAG 2580
GACACAGCGC AAACGTCAGC ATACTTACCA AACACGGTCC AACATAGAGC ATAATTCACA 2640
GGCATCATGT CAAAATTCAG GTGTACAGGA AGACTCAGAC AGTTCTTCAG AGGAAGATGA 2700
AACTGTTGGC ACAAGTGACG CTTCGGTAGA GGATCCTGTT GTTGAATGGC AAAGTGAAAG 2760
TTCTTCCAGT GACTCATCAA GTGAATATTC TGATTGGACA GCAGATGCTG GAATAAATTT 2820
ACAACCCCCA AAAAGACAAA CCAGACAGAC AACACGTAAA ATATGCAGCA GCTCTGATGA 2880
GGAAAATTTG AAGTCCCTAG AAGAAAGGCA GAAGAAACCT AAGCAGACTA GAAAGAAGAA 2940
AGGAGGACTG GTTTCTATAG CAGGTGAGCC TAATGAAGAA TGGTTTGCCC CTCAGTGGAT 3000
CTTGGATACT ATACCCCGAC GTTCCCCATT TGTCCCACAA ATGGGAGATG AGCTTATCTA 3060
TTTTAGGCAA GGACATGAAG CTTATGTTCG GGCTGTAAGG AAATCGAAAA TATACAGTGT 3120
TAATTTACAA AAACAGCCAT GGAACAAAAT GGATCTCAGG GAGCAAGAGT TTGTTAAGAT 3180
TGTAGGAATC AAATATGAGG TTGGCCCACC CACACTGTGC TGCTTGAAGC TTGCATTTCT 3240
GGACCCAATT TCAGGCAAAA TGACTGGAGA ATCTTTTTCC ATTAAGTATC ATGACATGCC 3300
GGATGTCATT GACTTCCTTG TGCTACATCA GTTTTATAAT GAAGCCAAAG AAAGGAACTG 3360
GCAGATTGGT GATAGATTCC GCAGTATAAT AGATGACGCC TGGTGGTTTG GGACTGTGGA 3420
GAGTCAGCAG CCTTTTCAAC CAGAGTATCC TGATAGTTCT TTCCAGTGTT ACAGTGTTCA 3480
CTGGGACAAT AATGAGAGAG AAAAGATGAG CCCATGGGAT ATGGAGCCAA TTCCAGAAGG 3540
AACTGCCTTT CCAGATGAAG TTGGTGCTGG TGTTCCTGTC TCCCAGGAAG AATTGACTGC 3600
TTTGCTATAC AAACCCCAGG AAGGAGAGTG GGGGGCTCAT TCCAGAGACG AAGAATGTGA 3660
ACGGGTTATT CAGGGCATCA ACCACCTTCT TTCCCTGGAT TTTGCCAGCC CTTTTGCTGT 3720
TCCAGTGGAT CTCAGTGCCT ACCCCTTGTA TTGTACTGTA GTTGCTTATC CAACTGACCT 3780
CAATACCATC AGGCGGAGAC TTGAAAATCG CTTTTACAGG AGAATATCAG CATTAATGTG 3840
GGAGGTACGC TATATTGAAC ATAATGCCAG GACTTTCAAT GAGCCAGACA GTCCTATAGT 3900
TAAAGCAGCT AAAATTGTAA CTGATGTCTT ACTTCGATTT ATTGGGGATC AGAGCTGTAC 3960
TGATATACTG GATACTTATA ATAAAATTAA AGCAGAAGAA CGAAACAGTA CTGATGCAGA 4020
GGAGGATACA GAAATTGTTG ATTTAGATTC AGACGGTCCT GGTACTTCAT CTGGAAGAAA 4080
GGTCAAATGC CGAGGCAGAA GACAGTCTTT AAAGTGTAAT CCTGATGCTT GGAAAAAACA 4140
ATGCAAGGAA CTATTGAGCC TCATTTATGA ACGTGAAGAC TCGGAGCCAT TTCGACAGCC 4200
AGCTGATCTT CTTTCTTACC CAGGTCATCA GGAGCAAGAG GGAGAATCCT CAGAGTCTGT 4260
TGTTCCAGAA AGACAACAAG ATTCATCTCT TTCTGAGGAT TATCAAGATG TTATAGATAC 4320
TCCTGTGGAC TTCAGCACTG TGAAAGAAAC TTTGGAAGCA GGAAACTATG GTAGTCCTCT 4380
GGAATTTTAT AAGGATGTTC GCCAAATATT CAACAACTCC AAAGCTTATA CCTCTAATAA 4440
AAAGTCAAGG ATCTATAGCA TGATGCTGCG ATTATCTGCC TTATTTGAAA GTCATATCAA 4500
AAATATCATC TCTGAATATA AGTCAGCAAT CCAGAGTCAG AAGAGGAGAA GGCCACGGTA 4560
CAGAAAACGT CTAAGAAGCA GCAGCAGTTC ATTATCTAGT AGTGGAGCAC CTAGTCCAAA 4620
AGGGAAGCAG AAACAAATGA AGTTGCAGCC TAAAAATGAC CAGAATACCT CAGTATCTCA 4680
TGCCAGGACT AGCTCTCCTT TCTCATCTCC TGTTTCAGAT GCTGCTGAAG GGCTTTCACT 4740
ATATCTACTT GATGATGAGC CAGATGGGCC ATTTTCTTCA TCGAGCTTCG GTGGATATAG 4800
CCGAAGTGGA AATAGCCATG ACCCAGGGAA AGCCAAATCA TTTCGGAATA GAGTTTTGCC 4860
AGTTAAACAA GATCACTCCC TTGATGGACC CCTTACAAAT GGTGATGGCA GAGAGCCCCG 4920
GACAGGAATC AAGAGAAAAC TACTTAGTGC ATCAGAAGAA GATGAAAACA TGGGAGGAGA 4980
AGATAAAGAG AAAAAAGAAA CAAAAGAGAA ATCTCATTTA TCCACCTCAG AGAGTGGAGA 5040
GTTAGGATCC AGTTTAAGTT CTGAAAGTAC CTGTGGTTCT GACTCTGACT CTGAATCAAC 5100
TTCCAGAACA GATCAAGATT ACGTAGATGG AGACCATGAT TATAGCAAAT TCATACAAAC 5160
CAGACCTAAA AGAAAACTCA GAAAGCAACA TGGCAATGGA AAAAGAAATT GGAAGACCAG 5220
AGGCACAGGA GGAAGAGGCA GATGGGGAAG ATGGGGTAGA TGGAGTAGAG GAGGCAGAGG 5280
AAGAGGAGGC AGGGGACGAG GGAGTCGAGG AAGAGGTGGA GGTGGCACTA GGGGGAGGGG 5340
AAGAGGGAGA GGAGGAAGAG GTGCTTCTAG AGGAGCTACC AGAGCCAAAC GAGCACGTAT 5400
TGCAGATGAT GAATTTGATA CCATGTTTTC AGGACGTTTC AGTAGACTGC CTCGAATTAA 5460
AACAAGAAAC CAAGGCAGGA GGACTGTTTT ATATAATGAT GATTCTGATA ATGACAATTT 5520
TGTGTCCACT GAGGATCCTC TGAATCTTGG TACATCCAGA TCAGGCAGAG TGCGTAAAAT 5580
GACAGAAAAA GCCAGGGTTA GCCATCTCAT GGGATGGAAT TATTAACAGT TAATAAATTT 5640
AGAATAACTT AAAAAATTCA ATGGCCTTCT ACTGCAGGGA ATTTACCAGG AAATCTACAA 5700
AGCAAGTTGT GTGGGGACTT CTGCTTCCTT TCACATTGGT GCTTTTCCAT TTATGCCAGT 5760
ATACATTTGT TTCAAGACTT TTGATCTCCA CACTTCATTT GTTCAAATAA GCCTTACTCA 5820
TTAGGCCTTA AATTAAAAGA AATTCTGCCC ACACACACAC AAACACATAC ACACACATAC 5880
ACACACACAG ACACACACAC ACGAAACACA ACACAGACAC TACAGATTTA CTACATTAAA 5940
GGAGCATTCA GCTTCTTAAG AGTAGCATGA CATTTTTATC TCAATAGAAT AGCCCTCTTT 6000
TGCTTTTGTA TCACAGAAGT ATAGCACCTT CTTACAGAGT TTTATATAGT TTGTTTTTGC 6060
CATTTTGATT CCTATACCCA GTAATAATAA CTTTTGCACA ATACACCAAT CCTAAAGGCA 6120
GCTATTAAAT GTTTACAGTT TCTATATTGT AAGAGCGATC TGGATTATTT TACTCTTCCC 6180
AGGCCAAACT TTCATGACTT GTACTGAACT GAAGTATATA TTTATACTAC AGTTTTTTGG 6240
GGGGTGGGGG GATCTTGATA TGCTTTTCAT TGATTTGCAT AATTCACGTT AAAGGTGAGA 6300
AAGGGTTGGT GCCTTGTAAA TATGTAGCAG ATCTTCGTGG TGTGTTCTGA TGTGTGCATT 6360
AACTTTATTA AAAAAGAATA CTTGAGGTAT CAATCTAGAC AAGGTGCCAA ATGCAAAAGT 6420
TTCCCGCATC AATTTTTTTC CTATCACATT TTATTGCATT AATAGAATTT GTGTAGCTTA 6480
AATAACTTAA ACATTTGAAA AATCCTCATC CACAAAGAAC AACTTCTTTG AACAGTAGCT 6540
CAGCTACCTC TTAACTACAA CTACTGGAAA CATTAAGGAA AATAGATGCT GTTATTCCTT 6600
ACTGACTAAG GAGAAATAGA ACAAGCTTAG TAGGAATGAA TACCCCATAA GTTATAAGCT 6660
GAGAGGTTGT TAATAATTGT ATTGGCTCTC AAATTAATAA TTGTAATTAA CAAAGTTTCA 6720
TAAATATAGT ATGCTCTACC ACCTTAGGCT TTCTTAGAAC ATATTTGTGT AAGTAGACTT 6780
GGGCTACTGC TTATATATTT CTGCTCCACT TACCATTTAA CAGCTGTGAG TTGCTGGTTT 6840
TCATTTGAAT CTTAAAATTT AACAAAGCAC CTGGTTTGAT TTGGAATGTT TTGGCTAGCT 6900
AGTATTATGA ATCAACTTAT AGATTCTGCT CATATCATTC CAAAGGGTTC TTCTGTTCTA 6960
GTCTTTCAGG AAAGAACCTT ATTGCACTGC ACACTCATGT TGTGAATCAT TATTTTATAG 7020
ATAAAAAACA TCTTTAAAAA CCCTTATTGT CTTGTTTACA GCAGTAGAGT GCACATGGTT 7080
CCATAAGTGA GCTTGAGTTC CAAGGTCAGT TTTACTCCCC AAATTTAATA TTACAGATTT 7140
GTTCATTTGT TAGATACTTA CATTTCTGAG GTAAGAGGGA TAATAGCAAT TTCTGTTTCT 7200
GTAACAGCAA ATTTGTTGCA CTTAGATCAG GCTCATGGGA TAAAACAGAC TTCTTAGTAT 7260
ATACCTAGCT ATCCCAGGAT ATTTCTTAAG CTAATGTGTT TGTCTCATGC TTTCAATCAT 7320
TTCATGCATC TGAAAACCCT TAAGTGCAGA GGAAGGCGTA CACACATAAA ACTTTGCTTT 7380
TTTGGTAGGG TCGGCAGTAG GGTTATTCTT GGACTAACAT CTTTAAGCAG TTTTCACTTG 7440
CAGTGGAAAT GATGTTCAGG CTTTAAGAGA AAGTATTGTG AATTGTTAAT GGCACTAACT 7500
TCTGTTACTA GACAGCAGAC CAAGCTATTT TTTTGTTGTA GTCTTTTTTT CACTAAACCA 7560
AAACTACTTC TGGTTGTAAC TCAGCTGCCA CTTTAAACCA TAGTAGAGAT TCAAAACGTT 7620
CCTATTTGAA ACTACATTTG ATTTTTGCTA AAATGTGCTG TTTCGGTTAT TTATCTCTTG 7680
GGCATTTAGA CTAAATTGTG CCTGTATTCC TGAAATCAAT AATACTTTGG CTTATCCTGA 7740
TCTAAGTAAC ATAGTTACTT AAATTCCTGG ATATACCCAA ATATGGATCA CATGTATCAT 7800
TTTAGTTTGA AATTTTTTGT TGACATTCTT CTATGAAGAG CTGACCTCTT GAAATGTAGA 7860
AGAATTGACA TTTGTGTGAT TTTGGCTATC TGGAGCTTTA TTTATAATTT ATTTTGAAAA 7920
ATAAAAATGC CACATTTATT TCCCAAATGT CAAGATTTTC TAGAATTAGA TAATTAGAAT 7980
AATAAGGCTG AAGACATTTT AAAGCATATT TTATATGTAG TGAAATACTG TGAAAATATT 8040
AGTGAACAGC ATTTTGCTGT AATGTTTATT TCAGTTATTA AGATTTAAAG AGTTAGTCAT 8100
CAGGGTATGT TAGATAAACA TAGTTATCAT TTATTAAACA AACAGATAAT TTTCTGTTTG 8160
CATGCAAATT ATTTTAATAA GTGTGAAAAT AAAAGTTTGG AAGATAGTAT TTTTACTTTT 8220
ATATCTGGAC TTTTTTTTCC CCCAATTTAC ACTTTGCTTT CTTGTAATAC CACCTCCTGT 8280
GAATGTGTTG TAATTAGTAT CACATTGATT ACTTTATCAT TTTAATTTCT TTGAGGCCCT 8340
TTAAACCTAC GTAAAATCTG GGTCCAGCCA TAGCAAAGCA AGTACAAAAT GAACAAAGAA 8400
TTTTGAAGAA AAGCCTAAAT CTTAAATTGC TAAGAAAAAA CACTGTTATA TTTAGGCCCG 8460
TGAGAGCATA TACATGTATA AACCTAATCC TATGCTAGAT ATGAATAGTC AGTGAGCTGT 8520
AATATTTCTC ATAAATGCTA ATAATGTTTA AATTCCCAGC TTTAAGATCT TAGTGTGTGT 8580
ATATATTTAT AAAATCTGAA TTGTGTGTTT CTTCTATGGC TTACTGTGTG TTTCTCTTTC 8640
AGCAATAGGA TGCTCTCTAA AACATTCACT AGCCTACTAG CCTACTTACT AAATTTTTGT 8700
ATATGTGTGT TTGTGCACTT GTATGTGTGT AAAGTTTTTT CCCCAACTTG ACACACCTTA 8760
TCTCAGACAT TCAAAAAAAG AGAACATTTT GTATGGAGGA CAGTCTGCCA ACTTTTTGCC 8820
TCTCTACAGC TCTTAGCCTG TATATTTACT GCTTGATCAT TCATTATGCC TTCTAGATAA 8880
CCAGTCCAGG TTTTGTCATA TACCTGTGTC CCTCTATTCT TTTTATTTCC CTTTTTAATT 8940
TTTTTTCTTT TTTTTCCCTC CCCAGAAATC AGGCTTGTGT TGGAATTCTT CTCTATAATA 9000
CTTTGTTTCC CGCAGATGCA AAGTAACAAA GTAACTGAGT AAAATTAGAA ATCTCATTCT 9060
GCACAACTGT GCGCTCAGAT ATTTAACTCA GCCTTCTAAT ACTTTTAAGT ACGTTTCTGT 9120
TATTTATCTT TTTGTTGTTT TTGTTTTAAT CCCATAGATT GTCATCAGAC AATAATAGAG 9180
TGATTGAGAG AGAAAGATAT AAATGCCACT TCTAACTTTT TGATAAAACT TTTTTGAGCA 9240
TTTTTCAAAA ATTTGTATGT TTGTGGTAAT GGGGAATTAA ACACCTTTTA CAGCTGATGT 9300
ATGTTGGAAA TCATTTTATG TACATTTACC AACTGGTACT TATCTTCAAG TTGGAATTTT 9360
CACATCCATA AAAGGGAGAC TTGCATCATA TATAATTTTC AGTATACTTT GCTGTCCAGC 9420
CTTTTAAACA ATTACAGTAA CATTTTGAGT TCTGTGATGA ATAGTTCTAG GGGAAGGGAT 9480
GGAACTTTCG ACATGTAAAG TCCATTGTTT TAAATGCTAA CCCCATCCCC AATATTTTTG 9540
TGGAACGTGA GGCTTTATGA AAGGTTTATC AGAAATAGAA TATTCTAAAG TCACTTTTAT 9600
GGCTTATTTC AAAAACTAGT GTGAAAGTAT TTTCATGCTT TTTTGTTTCT CATCTTTTAG 9660
CAAAGCTTCT TTACCAAGTT TTGATTAAAT TGCAATATAA AATTAAGTTT TTTCACGGTG 9720
CTATATTTTG TGGAATATGG GTAGCACTCA GGTTTCTTTC TTTTTTCTTT TCTCCTTCCT 9780
TCTTCCTTCA TTCCTTCATT CCTCCCTCCC CCCTCCCTCC CTCCCTCTCT TCCTTCCCTC 9840
CTTCCTTCCT TCCTCACCTC GGCCTCCCAA AGTGCTGGGA TTACAGGCAT GAGCCACCGT 9900
GCCCGGCCTA TATACCCTTA TTCTTGATTA TTTCTTTTTT CATCTTTTCA ATCCTGCTTA 9960
CTTTTATCCT CACTTTTCTT TCTGCCATGA AAACTGCACC TAATTTACCA CACTTAAGAT 10020
TGGCAATTTT TGATTCATTG ATGGGAGAAG TACAGTAGAA AGGCCCTGCA GTTTAGAATT 10080
AAGTTGTGTT TGTTTATTTA CATGTATGCC CATTTCTTCT AAATTAAATC TAGAATGTGA 10140
GACTTTGACA TATAAAAGCA TGATAAGTAT TTTCTTAAAA AATAAGACTA TTGATACATA 10200
ATGAAACCAC CATTGGTAAT TGAATTTTAA AATGATATGC AAAAATATTT AGAAATCCAG 10260
TTGGGAAATG TGTTTTTGCA TATGTCACCA GATACACATT AGGCAGTACT ACAAATGTTA 10320
ATTCTTAAAC AATACTGTGG TGATGGCAAT CAGTAATTTA TTTCTTTGTC CTGTAACTTA 10380
TCATTCTTGT CTTTTGTAAT GTCTTACACA GTATTAACAT AACTGTACCT TTTTTTTGTT 10440
CTTGGTATCC ATACATTTTA AGATGGAAAA TCAGTTCATA GTTGATATGA TATTGTATAT 10500
GGGCAAAATG TCCGTTAAAC TAAAATTCAG TAAAAAAGGT AATATAAACT GGCTTGATTT 10560
ATAAAAGATG TTTTGTTTGG CAGTTATCAG TCATTATAAG CAATTATCTT CAAAGACAAA 10620
AAAACTGGAC TAATTTGTTG CCATTCTTTA TGGGATGTTT ACAATAAAAT TCCAAGTTGT 10680
TTGGAATCAA TTGCACTCTT GCTGCTTTAT GCCTTAATTT ATGTACCAGA GAAAAATTAA 10740
CCAGAAGAAA GAAATATGGA GTTACCTATT CAGCTTTAGA GATTGTAACA TGTAACTCTT 10800
AGGTCTTTCT TGTTTCTTTG TCATAGAATA TTTTATTACT ATTACTTTTT AATCTGAGAA 10860
ACTAGGATGC TTCTTCCTAT CAAAGAAAAG GTTTTGTTTT TTGTTTTCAT CTTAGACATT 10920
GCAAATATTC TTTGGGTCAC TTTTAGGATA ATAAATATGA TGTTTACACT TTAAATGTGG 10980
GCTGCTTGGT GCATTCAATA ACAGCCTGCA AAGCATTTGT CAACATTTTG TTTTGCAGAG 11040
CTTTTCAAAA TGAATAGATC TCTAACATAT TTATGACTTA CAACTTTTAA CAGCTGAGTT 11100
ATATGTACCT GACATTTTAA AATGTATAGT AAGATTACCT ACATTGTAAA TGGTGCTTTA 11160
ATTCAGTGTA AGTGTAGGAG AGAGAGAAGT GAGGTGAGAT GATCTGAATG CTCTAACAGG 11220
AACATTCATA ACTATATAGT TACCCAGAAT TTGTCTCCCA GTGGCAAACA TTCCACTAGG 11280
TTCAAGATAA ATAAGCTGGC CAAAGACTGG ACTGTATCTT TGATATATAT ATACTGTGTA 11340
TTTTGTGTAT TTAGAATAAA AAAAATGCAT TTAGGAAAAA A 11382
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0103--Bromodomain
KW-0160--Chromosomal rearrangement
KW-0181--Complete proteome
KW-0225--Disease mutation
KW-0991--Mental retardation
KW-0597--Phosphoprotein
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat
--

Interpro

IPR001487--Bromodomain
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50014--BROMODOMAIN_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00439--Bromodomain
PF00400--WD40

Gene Ontology

GO:0005634--C:nucleus
GO:0007010--P:cytoskeleton organization
GO:0008360--P:regulation of cell shape
GO:0006357--P:regulation of transcription from RNA polymerase II promoter

Orthology
WERAM ID Ensembl Protein ID Species Identity E-value Score
WERAM-Nol-0024 ENSNLEP00000002950.1 Nomascus leucogenys 99 0.0 3071
WERAM-Paa-0144 ENSPANP00000008356.1 Papio anubis 99 0.0 3068
WERAM-Chs-0129 ENSCSAP00000006875.1 Chlorocebus sabaeus 99 0.0 3063
WERAM-Pat-0189 ENSPTRP00000037945.4 Pan troglodytes 99 0.0 3015
WERAM-Poa-0206 ENSPPYP00000022954.1 Pongo abelii 97 0.0 3006
WERAM-Mup-0143 ENSMPUP00000012519.1 Mustela putorius furo 97 0.0 2987
WERAM-Myl-0061 ENSMLUP00000005131.2 Myotis lucifugus 97 0.0 2980
WERAM-Caf-0186 ENSCAFP00000025568.3 Canis familiaris 97 0.0 2976
WERAM-Fec-0159 ENSFCAP00000025131.1 Felis catus 97 0.0 2974
WERAM-Ova-0006 ENSOARP00000000769.1 Ovis aries 96 0.0 2972
WERAM-Otg-0142 ENSOGAP00000012190.2 Otolemur garnettii 95 0.0 2972
WERAM-Loa-0035 ENSLAFP00000002269.3 Loxodonta africana 96 0.0 2962
WERAM-Mam-0092 ENSMMUP00000014099.2 Macaca mulatta 96 0.0 2939
WERAM-Mum-0215 ENSMUSP00000123588.1 Mus musculus 94 0.0 2921
WERAM-Ran-0020 ENSRNOP00000050434.5 Rattus norvegicus 94 0.0 2915
WERAM-Dan-0068 ENSDNOP00000007123.3 Dasypus novemcinctus 93 0.0 2864
WERAM-Tut-0100 ENSTTRP00000008495.1 Tursiops truncatus 93 0.0 2845
WERAM-Cap-0113 ENSCPOP00000008878.2 Cavia porcellus 89 0.0 2753
WERAM-Tas-0079 ENSTSYP00000007991.1 Tarsius syrichta 90 0.0 2724
WERAM-Bot-0148 ENSBTAP00000021597.4 Bos taurus 96 0.0 2700
WERAM-Eqc-0034 ENSECAP00000005860.1 Equus caballus 97 0.0 2683
WERAM-Gaga-0077 ENSGALP00000011572.4 Gallus gallus 82 0.0 2496
WERAM-Pes-0083 ENSPSIP00000010615.1 Pelodiscus sinensis 82 0.0 2450
WERAM-Tag-0037 ENSTGUP00000002638.1 Taeniopygia guttata 82 0.0 2424
WERAM-Fia-0058 ENSFALP00000004241.1 Ficedula albicollis 80 0.0 2421
WERAM-Ptv-0155 ENSPVAP00000012908.1 Pteropus vampyrus 98 0.0 2355
WERAM-Mod-0034 ENSMODP00000005304.3 Monodelphis domestica 76 0.0 2299
WERAM-Anc-0087 ENSACAP00000008364.3 Anolis carolinensis 79 0.0 2229
WERAM-Anp-0077 ENSAPLP00000009324.1 Anas platyrhynchos 80 0.0 2227
WERAM-Orc-0044 ENSOCUP00000004488.2 Oryctolagus cuniculus 95 0.0 2108
WERAM-Leo-0154 ENSLOCP00000018481.1 Lepisosteus oculatus 69 0.0 2090
WERAM-Sah-0194 ENSSHAP00000020977.1 Sarcophilus harrisii 82 0.0 1992
WERAM-Dar-0076 ENSDARP00000027753.10 Danio rerio 67 0.0 1928
WERAM-Orn-0048 ENSONIP00000005611.1 Oreochromis niloticus 67 0.0 1927
WERAM-Pof-0235 ENSPFOP00000019570.2 Poecilia formosa 67 0.0 1915
WERAM-Tar-0160 ENSTRUP00000034294.1 Takifugu rubripes 65 0.0 1907
WERAM-Gaa-0217 ENSGACP00000026878.2 Gasterosteus aculeatus 66 0.0 1895
WERAM-Ten-0142 ENSTNIP00000014771.1 Tetraodon nigroviridis 66 0.0 1886
WERAM-Orla-0096 ENSORLP00000011752.3 Oryzias latipes 67 0.0 1882
WERAM-Xim-0147 ENSXMAP00000012195.1 Xiphophorus maculatus 67 0.0 1873
WERAM-Gog-0041 ENSGGOP00000004047.2 Gorilla gorilla 93 0.0 1872
WERAM-Asm-0067 ENSAMXP00000007227.1 Astyanax mexicanus 68 0.0 1859
WERAM-Ora-0069 ENSOANP00000010247.1 Ornithorhynchus anatinus 63 0.0 1821
WERAM-Lac-0024 ENSLACP00000004089.1 Latimeria chalumnae 61 0.0 1800
WERAM-Caj-0153 ENSCJAP00000000500.2 Callithrix jacchus 62 0.0 1796
WERAM-Meg-0147 ENSMGAP00000015414.2 Meleagris gallopavo 62 0.0 1789
WERAM-Xet-0079 ENSXETP00000025715.4 Xenopus tropicalis 60 0.0 1770
WERAM-Soa-0103 ENSSARP00000009798.1 Sorex araneus 83 0.0 1474
WERAM-Vip-0028 ENSVPAP00000002708.1 Vicugna pacos 89 0.0 1457
WERAM-Dio-0029 ENSDORP00000003106.1 Dipodomys ordii 82 0.0 1416
WERAM-Ere-0133 ENSEEUP00000014027.1 Erinaceus europaeus 83 0.0 1345
WERAM-Mae-0125 ENSMEUP00000012711.1 Macropus eugenii 77 0.0 1137
WERAM-Aim-0144 ENSAMEP00000013622.1 Ailuropoda melanoleuca 65 0.0 1079
WERAM-Prc-0035 ENSPCAP00000003322.1 Procavia capensis 70 0.0 1013
WERAM-Ict-0049 ENSSTOP00000004095.2 Ictidomys tridecemlineatus 95 0.0 991
WERAM-Sus-0029 ENSSSCP00000004824.2 Sus scrofa 59 0.0 976
WERAM-Tub-0011 ENSTBEP00000001116.1 Tupaia belangeri 77 0.0 891
WERAM-Drm-0016 FBpp0083988 Drosophila melanogaster 49 0.0 668
WERAM-Mim-0071 ENSMICP00000006862.1 Microcebus murinus 82 0.0 643
WERAM-Chh-0023 ENSCHOP00000002306.1 Choloepus hoffmanni 77 3e-175 614
WERAM-Ocp-0001 ENSOPRP00000000332.1 Ochotona princeps 61 5e-171 600
WERAM-Gam-0106 ENSGMOP00000011171.1 Gadus morhua 54 2e-162 571
WERAM-Ect-0083 ENSETEP00000009469.1 Echinops telfairi 68 5e-150 530
WERAM-Cii-0032 ENSCINP00000012790.3 Ciona intestinalis 38 3e-109 394
WERAM-Pem-0055 ENSPMAP00000006254.1 Petromyzon marinus 54 4e-75 281
WERAM-Viv-0028 VIT_05s0077g01160.t01 Vitis vinifera 30 4e-74 278
WERAM-Tra-0184 Traes_5AS_1F04E10C7.2 Triticum aestivum 31 2e-72 272
WERAM-Brr-0054 Bra010036.1-P Brassica rapa 30 3e-72 272
WERAM-Art-0060 AT2G47410.1 Arabidopsis thaliana 30 4e-72 271
WERAM-Arl-0008 Al_scaffold_0004_3445 Arabidopsis lyrata 30 9e-72 270
WERAM-Bro-0130 Bo7g092740.1 Brassica oleracea 30 9e-72 270
WERAM-Prp-0095 EMJ23094 Prunus persica 31 1e-70 267
WERAM-Glm-0194 GLYMA15G15220.2 Glycine max 30 1e-70 266
WERAM-Pot-0117 POPTR_0010s15260.1 Populus trichocarpa 31 5e-70 264
WERAM-Amt-0066 ERN16745 Amborella trichopoda 30 2e-69 262
WERAM-Mua-0028 GSMUA_Achr11P20690_001 Musa acuminata 29 1e-68 259
WERAM-Php-0039 PP1S19_18V6.1 Physcomitrella patens 29 6e-67 254
WERAM-Thc-0058 EOY06689 Theobroma cacao 31 8e-66 250
WERAM-Osl-0029 ABO94205 Ostreococcus lucimarinus 26 1e-50 200
WERAM-Scs-0031 EDN94244 Sclerotinia sclerotiorum 30 1e-32 140
WERAM-Lab-0060 EDR06536 Laccaria bicolor 30 3e-29 129
WERAM-Ast-0012 CADATEAP00004711 Aspergillus terreus 28 7e-29 128
WERAM-Pytr-0032 EDU43562 Pyrenophora triticirepentis 28 9e-29 127
WERAM-Trv-0005 EHK19841 Trichoderma virens 31 2e-28 126
WERAM-Chg-0036 EAQ86947 Chaetomium globosum 29 1e-26 120
WERAM-Asn-0014 CADANIAP00002953 Aspergillus nidulans 26 1e-24 114
WERAM-Trr-0031 EGR47919 Trichoderma reesei 29 1e-23 110
WERAM-Asfu-0043 CADAFUAP00009687 Aspergillus fumigatus 26 9e-23 107
WERAM-Zyt-0022 Mycgr3P46654 Zymoseptoria tritici 24 4e-22 105
Created Date 25-Jun-2016