WERAM Information

Tag Content
WERAM ID WERAM-Hos-0123
Ensembl Protein ID ENSP00000347821.4
Uniprot Accession Q8TE76; MORC4_HUMAN; A1YR23; A1YR24; H7BXF1; Q5JUK7; Q96MZ2; Q9HAI7
Genbank Protein ID NP_001078823.1; NP_078933.3
Protein Name MORC family CW-type zinc finger protein 4
Genbank Nucleotide ID NM_001085354.2; NM_024657.4
Gene Name MORC4;ZCWCC2
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000133131.14 ENST00000355610.8 ENSP00000347821.4
ENSG00000133131.14 ENST00000255495.7 ENSP00000255495.7
Details
Type Family Domain Substrates AA References (PMIDs)
Me_Reader ZF-CW CW-type H3K4me2 K 26933034
Status Reviewed
Classification
Type Family E-value Score Start End
Me_Reader ZF-CW 3.40e-26 93.3 421 471
Organism Homo sapiens
NCBI Taxa ID 9606
Functional Description
(View)
Domain Profile
  Me_Reader ZF-CW
          ZF-CW.txt   2 geekvWvqCddClKWRrLpgevdasvlsekWiCinNsdvrynnCsvpeEsl 52 
                        +++++WvqCd+ClKWR+Lpg++d+s+l+++W+C++Ns+++y++CsvpeE++
  ENSP00000347821.4 421 VPDQTWVQCDECLKWRKLPGKIDPSMLPARWFCYYNSHPKYRRCSVPEEQE 471
                        689**********************************************96 PP
Protein Sequence
(Fasta)		MLLYRGAPAG PGAPGCGLAR PGGGPQAFGI RLSTMSPRYL QSNSSSHTRP FSAIAELLDN 60
AVDPDVSART VFIDVEEVKN KSCLTFTDDG CGMTPHKLHR MLSFGFTDKV IKKSQCPIGV 120
FGNGFKSGSM RLGKDALVFT KNGGTLTVGL LSQTYLECVQ AQAVIVPIVP FNQQNKKMII 180
TEDSLPSLEA ILNYSIFNRE NDLLAQFDAI PGKKGTRVLI WNIRRNKNGK SELDFDTDQY 240
DILVSDFDTE EKMTGGVTSE LPETEYSLRA FCGILYMKPR MKIFLRQKKV TTQMIAKSLA 300
NVEYDTYKPT FTNKQVRITF GFSCKNSNQF GIMMYHNNRL IKSFEKVGCQ VKPTRGEGVG 360
VIGVIECNFL KPAYNKQDFE YTKEYRLTIN ALAQKLNAYW KEKTSQDNFE TSTVARPIPK 420
VPDQTWVQCD ECLKWRKLPG KIDPSMLPAR WFCYYNSHPK YRRCSVPEEQ ELTDEDLCLS 480
KAKKQEQTVE EKKKMPMENE NHQVFSNPPK ILTVQEMAGL NNKTIGYEGI HSPSVLPSGG 540
EESRSPSLQL KPLDSSVLQF SSKYKWILGE EPVEKRRRLQ NEMTTPSLDY SMPAPYRRVE 600
APVAYPEGEN SHDKSSSERS TPPYLFPEYP EASKNTGQNR EVSILYPGAK DQRQGSLLPE 660
ELEDQMPRLV AEESNRGSTT INKEEVNKGP FVAVVGVAKG VRDSGAPIQL IPFNREELAE 720
RRKAVESWNP VPYSVASAAI PAAAIGEKAR GYEESEGHNT PKLKNQRELE ELKRTTEKLE 780
RVLAERNLFQ QKVEELEQER NHWQSEFKKV QHELVIYSTQ EAEGLYWSKK HMGYRQAEFQ 840
ILKAELERTK EEKQELKEKL KETETHLEML QKAQVSYRTP EGDDLERALA KLTRLRIHVS 900
YLLTSVLPHL ELREIGYDSE QVDGILYTVL EANHILD 937
Nucleotide Sequence
(Fasta)		ATATTTCTGT ACGGCCCAGA GGCAGCCCGG GCAGTCGCCG GGTCGGTAGA GGTGCTGACA 60
GGGCGGAGCC GCCGCTTGCC TCAGCCGGCC TCACCCCTCC CGCCCGGGAC AGGTGGCTGG 120
AGCGCGCTCC GCCTCCGCCA GCTGCGAGTG GGAGCGAGGG AGGGCCGGTC CCGGACGGTC 180
GCCGCCAGCT GCGAGTGGAA GTGAGCGAGG GCTAGTCCCG GACCGCCGGG CCAGGGGTCC 240
GGCGGCAGCA GACGGGTACC GTGGCGGCCA AAAAAATGCT CCTGTACCGA GGGGCCCCCG 300
CCGGCCCTGG CGCGCCGGGC TGCGGGCTGG CCCGGCCCGG CGGCGGCCCG CAGGCCTTCG 360
GGATCCGCCT GAGCACGATG AGCCCCCGCT ACCTCCAGAG CAACTCCAGC AGCCACACGC 420
GACCCTTCAG TGCCATCGCG GAGCTGCTAG ATAATGCTGT AGATCCAGAT GTATCTGCCA 480
GGACGGTCTT TATAGATGTT GAGGAGGTCA AGAATAAATC TTGTTTGACC TTTACCGATG 540
ATGGATGTGG GATGACACCT CATAAACTAC ACCGAATGCT CAGCTTTGGC TTTACAGATA 600
AAGTAATAAA GAAGAGCCAG TGTCCCATTG GGGTCTTTGG TAATGGTTTC AAGTCAGGCT 660
CCATGCGGCT AGGAAAGGAC GCCCTTGTCT TCACCAAGAA TGGGGGTACT CTCACTGTTG 720
GACTTCTATC ACAGACCTAT CTGGAATGTG TCCAGGCCCA GGCAGTTATT GTACCAATTG 780
TTCCATTCAA CCAGCAAAAC AAAAAAATGA TTATTACCGA GGATTCATTG CCCAGCCTAG 840
AAGCCATCTT GAACTATTCC ATTTTCAACC GTGAAAATGA CCTGCTGGCC CAGTTTGATG 900
CCATCCCAGG CAAAAAAGGC ACTCGTGTTC TCATTTGGAA CATCCGCAGA AATAAAAATG 960
GAAAATCTGA GTTGGACTTT GATACAGATC AATATGACAT CCTGGTATCA GACTTTGACA 1020
CAGAAGAAAA AATGACTGGC GGTGTTACCT CTGAGCTACC AGAAACAGAA TATTCTTTAA 1080
GGGCATTTTG TGGTATTCTA TACATGAAGC CACGCATGAA AATTTTTCTG CGTCAAAAGA 1140
AGGTGACTAC CCAGATGATT GCCAAGAGCC TGGCCAATGT AGAATATGAT ACATATAAAC 1200
CTACCTTCAC AAATAAGCAG GTGAGAATCA CCTTTGGGTT CTCTTGCAAG AATAGTAACC 1260
AGTTTGGAAT AATGATGTAT CATAACAACC GACTCATAAA ATCTTTTGAG AAGGTGGGGT 1320
GCCAGGTGAA GCCAACTCGT GGAGAAGGTG TAGGAGTAAT TGGAGTCATT GAGTGCAATT 1380
TCCTAAAACC TGCCTACAAC AAACAAGACT TTGAGTATAC CAAGGAGTAC CGGCTAACAA 1440
TAAATGCCCT TGCCCAGAAG CTCAATGCTT ACTGGAAGGA AAAAACATCT CAAGATAATT 1500
TTGAGACCTC AACTGTAGCC AGGCCAATAC CGAAGGTTCC TGACCAGACA TGGGTTCAGT 1560
GTGATGAGTG TCTTAAATGG AGAAAGCTTC CTGGGAAGAT TGATCCATCC ATGTTACCTG 1620
CAAGATGGTT TTGTTATTAT AATTCCCATC CAAAGTACAG GAGATGCTCT GTTCCAGAGG 1680
AACAAGAACT CACTGATGAA GACCTGTGCT TGAGCAAAGC TAAGAAACAA GAACAAACTG 1740
TTGAGGAGAA GAAGAAGATG CCTATGGAAA ATGAGAACCA CCAGGTATTC AGTAATCCAC 1800
CAAAGATCCT TACTGTTCAA GAAATGGCTG GATTGAATAA CAAGACAATT GGATATGAGG 1860
GAATTCATAG CCCTAGTGTG CTTCCTTCTG GTGGAGAAGA AAGCAGATCA CCATCTCTTC 1920
AACTTAAGCC TCTGGATTCC AGTGTTTTAC AGTTTTCCAG TAAGTACAAA TGGATCCTAG 1980
GTGAAGAACC GGTGGAGAAA CGAAGAAGGC TCCAGAATGA GATGACAACA CCTTCTCTAG 2040
ATTATTCCAT GCCTGCTCCT TACAGGAGGG TAGAAGCACC TGTTGCCTAC CCAGAAGGGG 2100
AGAACAGCCA TGATAAATCG AGTTCTGAGA GAAGTACACC ACCATACCTT TTCCCAGAAT 2160
ACCCAGAAGC AAGCAAGAAT ACAGGTCAGA ATAGGGAGGT TTCAATTCTG TATCCAGGGG 2220
CCAAAGACCA ACGCCAGGGG TCCCTGCTTC CTGAAGAATT AGAAGATCAG ATGCCAAGAT 2280
TGGTGGCAGA AGAATCTAAC AGAGGTAGCA CAACCATAAA CAAAGAAGAA GTCAACAAGG 2340
GACCTTTTGT AGCTGTTGTG GGTGTTGCCA AAGGTGTTAG AGATTCAGGA GCTCCCATTC 2400
AGCTGATCCC TTTTAACAGA GAGGAGCTTG CTGAGAGACG AAAAGCAGTT GAATCCTGGA 2460
ACCCAGTGCC TTATTCTGTG GCCTCTGCTG CAATCCCTGC TGCAGCCATT GGGGAGAAAG 2520
CAAGAGGCTA TGAGGAGAGC GAAGGTCATA ATACACCAAA GTTGAAGAAC CAGAGAGAGC 2580
TGGAAGAATT GAAGAGAACC ACAGAAAAAT TGGAACGTGT TTTGGCTGAA AGGAATTTGT 2640
TCCAGCAAAA GGTGGAGGAG CTGGAACAGG AGAGGAATCA CTGGCAGTCT GAATTCAAGA 2700
AAGTCCAACA TGAATTGGTG ATCTACAGTA CCCAGGAGGC GGAAGGCTTG TACTGGAGCA 2760
AGAAACACAT GGGTTATCGC CAAGCTGAAT TCCAGATTCT GAAAGCTGAG CTGGAAAGAA 2820
CCAAAGAGGA AAAGCAAGAG TTAAAAGAGA AACTGAAGGA AACAGAGACA CACCTGGAAA 2880
TGCTGCAGAA GGCTCAGGTC TCCTACCGGA CCCCAGAGGG AGATGACCTA GAAAGGGCTT 2940
TGGCAAAGCT TACGCGGCTA CGTATCCACG TCAGCTATCT CCTTACTTCT GTCCTCCCTC 3000
ACTTGGAGCT TCGTGAGATC GGGTATGACT CAGAACAAGT GGATGGGATC CTGTACACGG 3060
TGCTGGAGGC AAATCACATA CTGGATTGAG CACCAGACTG TATACCCTTC TCTTCTCTTA 3120
TCTTCTGTCT GTTCTCTTTT CTCTCCCTCC CTCACGTCTC TCTCTCTCTC TCTCTCTCTC 3180
TCTCTCTCTC TCTCTCACCC TCACCTTTAT GCCTTATATA GAGAATCTCT GTGTAAATCC 3240
TGGCTCATAA TCAGTCTCCT TTTTATCAGT TTTGGTGTGG AGAAAGAGGC CAGTTTAAAT 3300
AGGCTTTCAA GAGTCTAGGG TCAGAAAAGC AATAGTCACT AAGCTAGGTG ACCTGAAAGC 3360
TTTAATTTTC ATGACCTGGA TATGTGGTCT ATTGTATATC TTTTTCTGAA ATGGTTTGTA 3420
TTCATTTAGG TTAGATCAAT CAGCAGATAT TGGGTCCGGT ATACCAGGTA TTATTTTGGG 3480
GTAAGCTAAC AAGTACAACT CATGTTTGCA GCCTTCGAAG ATGTAACAAT CTCGTTGGAA 3540
ACATAAGACA TACATCACAT TATACACAAA AGTGTATGAT ATGTACAACT GAGTGGTACA 3600
GATATGACAT GGAAGATCTG GGGGAGGAAG TTCAAGGAAG GCACCACACC AGAAATGGGA 3660
CCTAAATTAA GGCTTAAAGA ATGAGCATGG CCACACTGTC AGTGAGTGTT CTTTAGGTGG 3720
TAGGACTATG GTTGATATTT TTCTTCTTCC TATCTTCCTG CCTTTTTCAG ATTTTCAATA 3780
TTAAACTTGT TATTCTTACA TTGGAAAAAA ATAAATTGTT TTTAAAAAGA TCAA 3835
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger
--
Interpro

IPR003594--HATPase_C
IPR011124--Znf_CW
PROSITE

PS51050--ZF_CW
Pfam

PF07496--zf-CW
Gene Ontology

GO:0005654--C:nucleoplasm
GO:0008270--F:zinc ion binding
Orthology
WERAM ID Ensembl Protein ID Species Identity E-value Score
WERAM-Chs-0112 ENSCSAP00000005411.1 Chlorocebus sabaeus 97 0.0 1634
WERAM-Mam-0114 ENSMMUP00000017277.2 Macaca mulatta 97 0.0 1620
WERAM-Orc-0127 ENSOCUP00000010875.3 Oryctolagus cuniculus 91 0.0 1538
WERAM-Loa-0116 ENSLAFP00000010331.3 Loxodonta africana 90 0.0 1515
WERAM-Aim-0039 ENSAMEP00000002915.1 Ailuropoda melanoleuca 90 0.0 1507
WERAM-Dan-0109 ENSDNOP00000013350.3 Dasypus novemcinctus 89 0.0 1491
WERAM-Paa-0186 ENSPANP00000009630.1 Papio anubis 98 0.0 1490
WERAM-Ova-0203 ENSOARP00000020250.1 Ovis aries 88 0.0 1490
WERAM-Mup-0037 ENSMPUP00000003708.1 Mustela putorius furo 89 0.0 1483
WERAM-Cap-0121 ENSCPOP00000009591.2 Cavia porcellus 86 0.0 1451
WERAM-Nol-0158 ENSNLEP00000016813.1 Nomascus leucogenys 92 0.0 1446
WERAM-Fec-0062 ENSFCAP00000005504.3 Felis catus 89 0.0 1436
WERAM-Poa-0208 ENSPPYP00000023066.2 Pongo abelii 99 0.0 1391
WERAM-Otg-0135 ENSOGAP00000011893.2 Otolemur garnettii 87 0.0 1379
WERAM-Eqc-0078 ENSECAP00000009922.1 Equus caballus 89 0.0 1373
WERAM-Ptv-0033 ENSPVAP00000003922.1 Pteropus vampyrus 84 0.0 1362
WERAM-Tas-0067 ENSTSYP00000006126.1 Tarsius syrichta 89 0.0 1354
WERAM-Caf-0191 ENSCAFP00000026515.3 Canis familiaris 88 0.0 1342
WERAM-Dio-0161 ENSDORP00000015212.1 Dipodomys ordii 80 0.0 1341
WERAM-Tut-0088 ENSTTRP00000007136.1 Tursiops truncatus 87 0.0 1320
WERAM-Mum-0120 ENSMUSP00000033811.7 Mus musculus 79 0.0 1246
WERAM-Gog-0136 ENSGGOP00000011626.2 Gorilla gorilla 99 0.0 1246
WERAM-Ict-0122 ENSSTOP00000012216.2 Ictidomys tridecemlineatus 88 0.0 1185
WERAM-Ect-0121 ENSETEP00000014203.1 Echinops telfairi 72 0.0 1169
WERAM-Pat-0191 ENSPTRP00000045043.3 Pan troglodytes 94 0.0 1107
WERAM-Ran-0257 ENSRNOP00000073417.1 Rattus norvegicus 78 0.0 1045
WERAM-Ere-0045 ENSEEUP00000003901.1 Erinaceus europaeus 78 0.0 975
WERAM-Vip-0057 ENSVPAP00000005364.1 Vicugna pacos 90 0.0 963
WERAM-Prc-0141 ENSPCAP00000012642.1 Procavia capensis 84 0.0 883
WERAM-Tub-0119 ENSTBEP00000013254.1 Tupaia belangeri 82 0.0 858
WERAM-Caj-0088 ENSCJAP00000014813.2 Callithrix jacchus 82 0.0 779
WERAM-Pes-0019 ENSPSIP00000004174.1 Pelodiscus sinensis 67 5e-173 605
WERAM-Lac-0119 ENSLACP00000014407.1 Latimeria chalumnae 45 1e-171 601
WERAM-Ora-0004 ENSOANP00000000609.2 Ornithorhynchus anatinus 69 3e-169 593
WERAM-Soa-0020 ENSSARP00000002072.1 Sorex araneus 70 2e-163 573
WERAM-Gaga-0145 ENSGALP00000025794.4 Gallus gallus 58 1e-151 534
WERAM-Meg-0146 ENSMGAP00000015395.1 Meleagris gallopavo 57 1e-150 531
WERAM-Mod-0189 ENSMODP00000026271.3 Monodelphis domestica 57 2e-150 530
WERAM-Ocp-0091 ENSOPRP00000008186.2 Ochotona princeps 57 9e-148 521
WERAM-Xet-0087 ENSXETP00000028509.3 Xenopus tropicalis 55 3e-147 520
WERAM-Anp-0132 ENSAPLP00000014493.1 Anas platyrhynchos 57 6e-147 519
WERAM-Tag-0069 ENSTGUP00000004962.1 Taeniopygia guttata 56 6e-147 519
WERAM-Bot-0112 ENSBTAP00000015758.4 Bos taurus 56 2e-146 517
WERAM-Myl-0142 ENSMLUP00000011489.2 Myotis lucifugus 58 5e-146 516
WERAM-Sus-0083 ENSSSCP00000012835.2 Sus scrofa 56 1e-144 511
WERAM-Anc-0135 ENSACAP00000012415.3 Anolis carolinensis 55 4e-144 509
WERAM-Leo-0063 ENSLOCP00000008264.1 Lepisosteus oculatus 55 2e-139 494
WERAM-Dar-0117 ENSDARP00000091859.3 Danio rerio 52 4e-136 483
WERAM-Orn-0194 ENSONIP00000020127.1 Oreochromis niloticus 52 2e-131 467
WERAM-Pof-0008 ENSPFOP00000022200.1 Poecilia formosa 51 2e-129 461
WERAM-Asm-0132 ENSAMXP00000012850.1 Astyanax mexicanus 51 2e-125 448
WERAM-Xim-0044 ENSXMAP00000004148.1 Xiphophorus maculatus 50 3e-125 447
WERAM-Fia-0132 ENSFALP00000010864.1 Ficedula albicollis 56 6e-123 439
WERAM-Ten-0171 ENSTNIP00000016946.1 Tetraodon nigroviridis 52 2e-122 437
WERAM-Tar-0137 ENSTRUP00000029898.1 Takifugu rubripes 51 3e-122 437
WERAM-Gaa-0029 ENSGACP00000004852.1 Gasterosteus aculeatus 49 1e-117 421
WERAM-Chh-0109 ENSCHOP00000011938.1 Choloepus hoffmanni 52 1e-112 405
WERAM-Mae-0140 ENSMEUP00000014217.1 Macropus eugenii 49 3e-74 277
WERAM-Osl-0014 ABO99126 Ostreococcus lucimarinus 34 6e-36 150
WERAM-Lep-0028 LPERR02G16340.1 Leersia perrieri 42 1e-08 59.7
WERAM-Mim-0033 ENSMICP00000003055.1 Microcebus murinus 50 1e-07 56.2
WERAM-Sol-0077 Solyc06g059960.2.1 Solanum lycopersicum 31 2e-07 56.2
WERAM-Bro-0120 Bo6g121240.1 Brassica oleracea 39 2e-07 55.8
WERAM-Arl-0052 fgenesh2_kg.2__ 2024__ AT1G77300.1 Arabidopsis lyrata 41 3e-07 55.1
WERAM-Thc-0097 EOY16446 Theobroma cacao 41 3e-07 55.1
WERAM-Chr-0033 EDP02327 Chlamydomonas reinhardtii 43 3e-07 55.1
WERAM-Sah-0006 ENSSHAP00000000215.1 Sarcophilus harrisii 47 5e-07 54.7
WERAM-Art-0032 AT1G77300.1 Arabidopsis thaliana 39 5e-07 54.7
WERAM-Pot-0026 POPTR_0002s07930.1 Populus trichocarpa 37 5e-07 54.7
WERAM-Brr-0078 Bra015678.1-P Brassica rapa 30 7e-07 53.9
WERAM-Sei-0057 Si016071m Setaria italica 33 9e-07 53.5
Created Date 25-Jun-2016