Tag |
Content |
WERAM ID |
WERAM-Hos-0129 |
Ensembl Protein ID |
ENSP00000346175.5 |
Uniprot Accession |
Q96T68; SETB2_HUMAN; Q5TC65; Q5TC66; Q5W0A7; Q659A7; Q86UD6; Q96AI6 |
Genbank Protein ID |
NP_001153780.1; NP_114121.2; XP_011533571.1; XP_011533572.1; XP_011533573.1 |
Protein Name |
Histone-lysine N-methyltransferase SETDB2 |
Genbank Nucleotide ID |
NM_001160308.2; NM_031915.2; XM_011535269.1; XM_011535270.1; XM_011535271.1 |
Gene Name |
SETDB2;CLLD8;CLLL8;KMT1F;C13orf4 |
Ensembl Information |
|
Details |
|
Status |
Reviewed |
Classification |
Type |
Family |
E-value |
Score |
Start |
End |
HMT |
SUV39 |
2.80e-57 |
195.2 |
71 |
694 |
|
Organism |
Homo sapiens |
NCBI Taxa ID |
9606 |
Functional Description (View)Functional Description
Histone methyltransferase involved in left-right axis specification in early development and mitosis. Specifically trimethylates 'Lys-9' of histone H3 (H3K9me3). H3K9me3 is a specific tag for epigenetic transcriptional repression that recruits HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Contributes to H3K9me3 in both the interspersed repetitive elements and centromere-associated repeats. Plays a role in chromosome condensation and segregation during mitosis. |
Histone methyltransferase involved in left-right axis specification in early development and mitosis. Specifically trimethylates 'Lys-9' of histone H3 (H3K9me3). H3K9me3 is a specific tag for epigenetic transcriptional repression that recruits HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Contributes to H3K9me3 in both the interspersed repetitive elements and centromere-associated repeats. Plays a role in chromosome condensation and segregation during mitosis.
|
Domain Profile |
HMT SUV39
SUV39.txt 79 sntrqekdkeese 91 +++++ + ++++ ENSP00000346175.5 71 ASQKEVNAQSSDP 83 2222222222222 PP SUV39.txt 1 vrLqvfktenkGwGvrclddiakgsFvciyaGeiltddeaeke.gl...eegdeyladldskesv..enlkegyesdvplssdss....... 79 vrLqvfkte+kGwGvrclddi++g+Fvciy+G++l+++++ek+ g+ +++++++++ sk+++ +++++++++ +pl+ +++ ENSP00000346175.5 367 VRLQVFKTEQKGWGVRCLDDIDRGTFVCIYSGRLLSRANTEKSyGIdenGRDENTMKNIFSKKRKleVACSDCEVEVLPLGLETHprtakte 458 79****************************************976676688999********999999************************ PP SUV39.txt 80 ............................................................................................ 79 ENSP00000346175.5 459 kcppkfsnnpkeltvetkydnisriqyhsvirdpesktaifqhngkkmefvssesvtpedndgfkpprehlnsktkgaqkdsssnhvdefed 550 ******************************************************************************************** PP SUV39.txt 80 .........................................................................ntrqekdkeeseyiidakk 98 +++ +k+++ +++++da+k ENSP00000346175.5 551 nlliesdviditkyreetpprsrcnqattldnqnikkaievqiqkpqegrstacqrqqvfcdeellsetkntsSDSLTKFNKGNVFLLDATK 642 ***********************************************************************999999*************** PP SUV39.txt 99 egnvgrflnHscspNlfvqnvfvdthdlrfprvafFaskrikagtELtwdYg 150 egnvgrflnHsc+pNl+vqnvfv+th+++fp vafF+++++ka+tELtwdYg ENSP00000346175.5 643 EGNVGRFLNHSCCPNLLVQNVFVETHNRNFPLVAFFTNRYVKARTELTWDYG 694 ***************************************************6 PP
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Protein Sequence (Fasta) | MGEKNGDAKT FWMELEDDGK VDFIFEQVQN VLQSLKQKIK DGSATNKEYI QAMILVNEAT 60 IINSSTSIKG ASQKEVNAQS SDPMPVTQKE QENKSNAFPS TSCENSFPED CTFLTTENKE 120 ILSLEDKVVD FREKDSSSNL SYQSHDCSGA CLMKMPLNLK GENPLQLPIK CHFQRRHAKT 180 NSHSSALHVS YKTPCGRSLR NVEEVFRYLL ETECNFLFTD NFSFNTYVQL ARNYPKQKEV 240 VSDVDISNGV ESVPISFCNE IDSRKLPQFK YRKTVWPRAY NLTNFSSMFT DSCDCSEGCI 300 DITKCACLQL TARNAKTSPL SSDKITTGYK YKRLQRQIPT GIYECSLLCK CNRQLCQNRV 360 VQHGPQVRLQ VFKTEQKGWG VRCLDDIDRG TFVCIYSGRL LSRANTEKSY GIDENGRDEN 420 TMKNIFSKKR KLEVACSDCE VEVLPLGLET HPRTAKTEKC PPKFSNNPKE LTVETKYDNI 480 SRIQYHSVIR DPESKTAIFQ HNGKKMEFVS SESVTPEDND GFKPPREHLN SKTKGAQKDS 540 SSNHVDEFED NLLIESDVID ITKYREETPP RSRCNQATTL DNQNIKKAIE VQIQKPQEGR 600 STACQRQQVF CDEELLSETK NTSSDSLTKF NKGNVFLLDA TKEGNVGRFL NHSCCPNLLV 660 QNVFVETHNR NFPLVAFFTN RYVKARTELT WDYGYEAGTV PEKEIFCQCG VNKCRKKIL 719Protein Fasta Sequence
>ENSP00000346175.5|SETDB2;CLLD8;CLLL8;KMT1F;C13orf4|Homo sapiens MGEKNGDAKTFWMELEDDGKVDFIFEQVQNVLQSLKQKIKDGSATNKEYIQAMILVNEATIINSSTSIKGASQKEVNAQSSDPMPVTQKEQENKSNAFPSTSCENSFPEDCTFLTTENKEILSLEDKVVDFREKDSSSNLSYQSHDCSGACLMKMPLNLKGENPLQLPIKCHFQRRHAKTNSHSSALHVSYKTPCGRSLRNVEEVFRYLLETECNFLFTDNFSFNTYVQLARNYPKQKEVVSDVDISNGVESVPISFCNEIDSRKLPQFKYRKTVWPRAYNLTNFSSMFTDSCDCSEGCIDITKCACLQLTARNAKTSPLSSDKITTGYKYKRLQRQIPTGIYECSLLCKCNRQLCQNRVVQHGPQVRLQVFKTEQKGWGVRCLDDIDRGTFVCIYSGRLLSRANTEKSYGIDENGRDENTMKNIFSKKRKLEVACSDCEVEVLPLGLETHPRTAKTEKCPPKFSNNPKELTVETKYDNISRIQYHSVIRDPESKTAIFQHNGKKMEFVSSESVTPEDNDGFKPPREHLNSKTKGAQKDSSSNHVDEFEDNLLIESDVIDITKYREETPPRSRCNQATTLDNQNIKKAIEVQIQKPQEGRSTACQRQQVFCDEELLSETKNTSSDSLTKFNKGNVFLLDATKEGNVGRFLNHSCCPNLLVQNVFVETHNRNFPLVAFFTNRYVKARTELTWDYGYEAGTVPEKEIFCQCGVNKCRKKIL
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Nucleotide Sequence (Fasta) | CCTGCGCTCG GGAGGTTTGG GCGGCTTGGC GTCGGAGGAG AGCCCCACCC GCGGAGGAAC 60 CCAGCCTTGC CAACGGAGCT GGCGGAGCTC ACTCCTCAGG TCAGGCGGGC GGCGTAGAAA 120 ACGCAGCGGA GCCAGGTGAA ACCAAGGCAC CGCCGTGGCT GGCCCCCGAC AGTTCCTCTA 180 GCCGGGAGGT TGGAGGAGCT GAAAACGCCG CGGAGCCCTC GGCCGCCCGA GCAGGGGCTG 240 GACCCCAGCC CTTGCAGCCT CCCTTCTCCT GGCACCCAAG TGCAGTCCTG GCTGCAGAAG 300 GGGCCGCGGG CGCACTGAGT TTCCAACCTC CATTTCAGCC TGTCTGTCTC AGGGTGCAGC 360 CTTAATGAGA GGTGATTCCT AAGCTGCTGG GAACCTGAGG TTGTCAAAGG GGCGGCAGGA 420 AATGGACAGC AGTATAAAAC CCAGAAGCAG AACTTGAAGG TTAAACCACT AGCCCATTTC 480 ACAGAATGTT TCATCCATTT GTGGACCAAA AGATGGAGTT GGTTTTTATT TTTAAAAAGA 540 TAATGTTAAT GATCTGATAC CACTACAAAT ATTTACGTGA GAAGATTCAT GGACTTGTCT 600 TTTGGTTGGA CTGTCACTCA TTTCTGAAAG TTTCTTCAGC CACAATTTCT ATTTGAAAAT 660 TCAAGTATCA AAGGATACCA GGTTTAGAAT GGTATAATGA TGTATTTTGT CTGAGGACTG 720 CAAATTTTAT AGAGACCACA GTTGGATTCC AGTGATATTC TGCAATCAAA GTGATTTGAT 780 AAACCTAATT TTGAAGCATT TTATATTTAT AAGCGACATC AAAAGATGGG AGAAAAAAAT 840 GGCGATGCAA AAACTTTCTG GATGGAGCTA GAAGATGATG GAAAAGTGGA CTTCATTTTT 900 GAACAAGTAC AAAATGTGCT GCAGTCACTG AAACAAAAGA TCAAAGATGG GTCTGCCACC 960 AATAAAGAAT ACATCCAAGC AATGATTCTA GTGAATGAAG CAACTATAAT TAACAGTTCA 1020 ACATCAATAA AGGGAGCATC ACAGAAAGAA GTGAATGCCC AAAGCAGTGA TCCTATGCCT 1080 GTGACTCAGA AGGAACAGGA AAACAAATCC AATGCATTTC CCTCTACATC ATGTGAAAAC 1140 TCCTTTCCAG AAGACTGTAC ATTTCTAACA ACAGAAAATA AGGAAATTCT CTCTCTTGAA 1200 GATAAAGTTG TAGACTTTAG AGAAAAAGAC TCATCTTCGA ATTTATCTTA CCAAAGTCAT 1260 GACTGCTCTG GTGCTTGTCT GATGAAAATG CCACTGAACT TGAAGGGAGA AAACCCTCTG 1320 CAGCTGCCAA TCAAATGTCA CTTCCAAAGA CGACATGCAA AGACAAACTC TCATTCTTCA 1380 GCACTCCACG TGAGTTATAA AACCCCTTGT GGAAGGAGTC TACGAAACGT GGAGGAAGTT 1440 TTTCGTTACC TGCTTGAGAC AGAGTGTAAC TTTTTATTTA CAGATAACTT TTCTTTCAAT 1500 ACCTATGTTC AGTTGGCTCG GAATTACCCA AAGCAAAAAG AAGTTGTTTC TGATGTGGAT 1560 ATTAGCAATG GAGTGGAATC AGTGCCCATT TCTTTCTGTA ATGAAATTGA CAGTAGAAAG 1620 CTCCCACAGT TTAAGTACAG AAAGACTGTG TGGCCTCGAG CATATAATCT AACCAACTTT 1680 TCCAGCATGT TTACTGATTC CTGTGACTGC TCTGAGGGCT GCATAGACAT AACAAAATGT 1740 GCATGTCTTC AACTGACAGC AAGGAATGCC AAAACTTCCC CCTTGTCAAG TGACAAAATA 1800 ACCACTGGAT ATAAATATAA AAGACTACAG AGACAGATTC CTACTGGCAT TTATGAATGC 1860 AGCCTTTTGT GCAAATGTAA TCGACAATTG TGTCAAAACC GAGTTGTCCA ACATGGTCCT 1920 CAAGTGAGGT TACAGGTGTT CAAAACTGAG CAGAAGGGAT GGGGTGTACG CTGTCTAGAT 1980 GACATTGACA GAGGGACATT TGTTTGCATT TATTCAGGAA GATTACTAAG CAGAGCTAAC 2040 ACTGAAAAAT CTTATGGTAT TGATGAAAAC GGGAGAGATG AGAATACTAT GAAAAATATA 2100 TTTTCAAAAA AGAGGAAATT AGAAGTTGCA TGTTCAGATT GTGAAGTTGA AGTTCTCCCA 2160 TTAGGATTGG AAACACATCC TAGAACTGCT AAAACTGAGA AATGTCCACC AAAGTTCAGT 2220 AATAATCCCA AGGAGCTTAC TGTGGAAACG AAATATGATA ATATTTCAAG AATTCAATAT 2280 CATTCAGTTA TTAGAGATCC TGAATCCAAG ACAGCCATTT TTCAACACAA TGGGAAAAAA 2340 ATGGAATTTG TTTCCTCGGA GTCTGTCACT CCAGAAGATA ATGATGGATT TAAACCACCC 2400 CGAGAGCATC TGAACTCTAA AACCAAGGGA GCACAAAAGG ACTCAAGTTC AAACCATGTT 2460 GATGAGTTTG AAGATAATCT GCTGATTGAA TCAGATGTGA TAGATATAAC TAAATATAGA 2520 GAAGAAACTC CACCAAGGAG CAGATGTAAC CAGGCGACCA CATTGGATAA TCAGAATATT 2580 AAAAAGGCAA TTGAGGTTCA AATTCAGAAA CCCCAAGAGG GACGATCTAC AGCATGTCAA 2640 AGACAGCAGG TATTTTGTGA TGAAGAGTTG CTAAGTGAAA CCAAGAATAC TTCATCTGAT 2700 TCTCTAACAA AGTTCAATAA AGGGAATGTG TTTTTATTGG ATGCCACAAA AGAAGGAAAT 2760 GTCGGCCGCT TCCTTAATCA TAGTTGTTGC CCAAATCTCT TGGTACAGAA TGTTTTTGTA 2820 GAAACACACA ACAGGAATTT TCCATTGGTG GCATTCTTCA CCAACAGGTA TGTGAAAGCA 2880 AGAACAGAGC TAACATGGGA TTATGGCTAT GAAGCTGGGA CTGTGCCTGA GAAGGAAATC 2940 TTCTGCCAAT GTGGGGTTAA TAAATGTAGA AAAAAAATAT TATAAATATG TAACTAACGC 3000 CTGTTTGTGA AATTAGCTTA TCAGGCTGAA ATTAAAGCCA TGCAAAAGAA GGTCTAGGTC 3060 CATCAAGGAA ATTCCCCTCC GTTTTCCTTT GTCATGGGGT TTATGTTTTA TTTCAGATTT 3120 TATTTGTGTG ACTTAGAAAT TCCAGGAACA CAATTAGGAT ATTTTCATAC ACATAGGGTA 3180 TCTTGTTCAC TGCTGTGCTA CTTTACATGA GTAGGATGGA AGTGTATATT TTATATGAAA 3240 TACCACTGTA CAATTTATAA TTTATTTACA AATTATATAT TAAGAGAAAC AAATGTCATA 3300 ACAGAACTCA GCTGTTTCTA ATTGCTTTTG TGACTGTTAC CTTTTAGTTC ATGCCCCCCC 3360 AAAGAGCTAA ATTTCACATT TTTACCTACA AAATTGATTT TTAATTCCTG GCAAATAATT 3420 TACCATTATG AGCTACAAGG TGGGCAACAG CGCCTGAGGA TCTAATTTTA TGCATATTAC 3480 TCCCAAGTAT TTTAACACTT GTTGGAGAAG CAATATCTGG ATCGATAAAA CACTGTCCCA 3540 TCAACCATTT GAGTGGGGAG AGGGAGAAGC TCTTCTGTAA GTAAGATTCT GGCAAGCTCT 3600 TTGAAATGAG TCTTCTTTCC CACAGATTTT CTCTACTCTT TCTATACAAA CAGATAGGAG 3660 AAGAGGGAAT AGAAACCTGG AGGAACTTGA ATATTTTTGT TCTAGATAGA GATACAGTTA 3720 CTGAAAAGGA AACCTAGAAA GTAGTCACAC GTTGCTTATT TAGGCCAGAA GTAATTGTAC 3780 TGGGCAAAAA TTTCACTTAA AAAACACAAG AAGTCCAGGT ATGGTGGCTC AGACCTGTAA 3840 TCCCAGCACT TTGAGAGGCC GAGGCAGGTG GATTACTTGA GCCTAGGGGT TCAAGACCAG 3900 CTTGGGCAAC ATGTCAAAAC CCTGTCTCTA CAAAAAATAC AAAAATTAGC CTGGCATGAT 3960 GGCATGTGCC CGTAGTCTCA GCTACTCAGG AGTGAGGTGG GAGGATCATT TGAGCTCAGA 4020 AGGTCAAGGC TGCAATGAGA CATAATTTCA CCATAGTACT TCCAGCCTGG GCAATAGAGC 4080 AAGACTCTCT CTCAAAAAAA ACAGCACACA CACACACACA CGAAAACAAT TCTGAACTAT 4140 GAAATCTGAA ACAGCCCCTT GGTATCTCCT GGGCATGATT TGCAAATCTT TTTTTTTTAC 4200 AGAAAAAAGG CAAAGAGTAA GCACTTTGCC ATAGGTTACT TGGCCGTGAT CATCTATCTA 4260 GTGGAAAAGG GGACTGGGAA GCCCAAGCAG ACTGGGAAAC CAGACAGCTA GGAAAAGGAG 4320 CAAAACATAG CCCAGCAACC TACAGATGAA GAAAGTTGAG AAATCCATTT ATTCACCATA 4380 GAGACGCAGG AATTTCAGGC AATGCACTAA AATGAAATGG GGGAAAAAAG CTTGATCAGT 4440 ATGGGAACCA TTTTTGTGCA AAAGGGAATA TTATGGATCA GCCAGTATTT CTTTGAGCTC 4500 TGCCTGTGGA GTCCATTTGA CCTTTAGAAA TATGAGGTAT TCTGTCAGTT TTATCTTCTT 4560 GGAGAAATTT CTCCTAAAAT CTTGATTTGC TTTAGTCTGG ACTGGTTCAT AGCCATCATC 4620 TTCCATCAGT ACCCCAGAGA TTCACTTTGT CTCTTATGTG GGATCTGTTT CCAGTTAGAT 4680 GCCATTATTT TCCTTTTCCT TGGTTTACTC TTCCACATAT TGGTAAAGCT CTTCCAATAG 4740 CTTTTGGAAA GGAAAAATGA AAAGTAAATG TTTTGAATCT CTGTGTGTTT GACAATGTCT 4800 TTATTTTACC CTTATACCTG ATTGCTGTTT TGGTTGGCAA GGTATAGGAT TCTTTAGTGG 4860 TCTCCATGCC CAGTTTTGAA GACATCTGCT AGCTTTCAGT GCTGTTGCTG TGGAGTCTGA 4920 AAATCTGTCT TCTGGCTTCC AGGGTGACTA CTGGAAATTG AATGCCATTC TGTTCCTTCT 4980 CTTTTGCATA TATAATCCAT TTTTATCTCT CTTGAAGCTT ATAGGTTTAT CTTTGTCTCA 5040 ATGTTCTGTC CCTGTTAAGA GTCCATTTTC ATCCTTTGTA CTAGGTGCCT GGTGGGATCA 5100 TTCCGTCTGA AACTAATGAT TTCCCATCTC TTCACTGTTT CTGGAATTCC TGTTTTCCAG 5160 ATGTTAGACC TCCAGAATTT GATCTCTAAT TTTCCTATCT TTTCTCTTAA CTTTCAGCTC 5220 TGTCTTCTTG CTAGGACCTT TTCCTAGGAG CATTTCTCAA TTTAATCTTC CAGTTCATCT 5280 GTTGCATTTT ATTTTTCTAG TCTCATATTG TCTCATATTT TTAATTTCTA AGAGCTCCCC 5340 TTCTCCGAAT ATTCTTTTTT TTTAATAGCA TCCTATTTTG GCTCATGGTT GCAGTATTTT 5400 ATCTCCTTGA AGATGTTTGT GTGTTTATGT ATGTATATGC ACACACGTAT ACATACACAT 5460 ACAGGCATGC ATCTCTGTAT TCTTTCGGCA TAATCTGTGT CCTCCAGGGT TTGTTTCTTT 5520 GTTTCCCCTG TATGTTTGTT TTGGTCGTTC ACATTATAGG CTTTCCTCAG AGTTAATGGT 5580 CTTGGTAGTC TACTCATATT TAAGTGTGGA ACACCAAAAA GCTTACTATA AGCTGAGAGT 5640 GTGGTAAAGG GCTCTTTGTT TTACTATGAC CTACCTGAGC TATCTTGCTG GGGAACACCC 5700 TAATGTCAGT CTCTTTATAA AGGGCCTTTC ATTTTGGCCT GGCAAGAAAT ACTCTTTCAT 5760 CCTCCTGCAT GGAGGGCAAA AAAAAATTTA AAAATTGGCT GCTAGGGTCT GTCTGCTCAC 5820 TTCCCTGTTT TGCAGACCCC ACACTCTTCT GCAATTCATT TCATAGTTGT CAAGACTATA 5880 CAAATTGTCC TTTTTAATGT TCTCTCTTCT GCTATCCCTA GTTGGCAGTC TTCCTCTTTA 5940 CAACCTGCTG AAAGTGGAAG ACCTCCAGTT TTCCTTTAAT TCCTCAGCAA ACCACCAACT 6000 ATTATATGTC TTTTTTCCAG AACAACTTAT TTTTTAACTA TAATTATATG CATTTATGTT 6060 AGATTCACTG AAAACCTCAT CTTGTATGGT GCTCTGTACC CTATGGGTGC TAAATAAAGG 6120 CTTGCTACTG GCAACTGGA
Nucleotide Fasta Sequence
>ENSP00000346175.5|SUV39|Homo sapiens CCTGCGCTCGGGAGGTTTGGGCGGCTTGGCGTCGGAGGAGAGCCCCACCCGCGGAGGAACCCAGCCTTGCCAACGGAGCTGGCGGAGCTCACTCCTCAGGTCAGGCGGGCGGCGTAGAAAACGCAGCGGAGCCAGGTGAAACCAAGGCACCGCCGTGGCTGGCCCCCGACAGTTCCTCTAGCCGGGAGGTTGGAGGAGCTGAAAACGCCGCGGAGCCCTCGGCCGCCCGAGCAGGGGCTGGACCCCAGCCCTTGCAGCCTCCCTTCTCCTGGCACCCAAGTGCAGTCCTGGCTGCAGAAGGGGCCGCGGGCGCACTGAGTTTCCAACCTCCATTTCAGCCTGTCTGTCTCAGGGTGCAGCCTTAATGAGAGGTGATTCCTAAGCTGCTGGGAACCTGAGGTTGTCAAAGGGGCGGCAGGAAATGGACAGCAGTATAAAACCCAGAAGCAGAACTTGAAGGTTAAACCACTAGCCCATTTCACAGAATGTTTCATCCATTTGTGGACCAAAAGATGGAGTTGGTTTTTATTTTTAAAAAGATAATGTTAATGATCTGATACCACTACAAATATTTACGTGAGAAGATTCATGGACTTGTCTTTTGGTTGGACTGTCACTCATTTCTGAAAGTTTCTTCAGCCACAATTTCTATTTGAAAATTCAAGTATCAAAGGATACCAGGTTTAGAATGGTATAATGATGTATTTTGTCTGAGGACTGCAAATTTTATAGAGACCACAGTTGGATTCCAGTGATATTCTGCAATCAAAGTGATTTGATAAACCTAATTTTGAAGCATTTTATATTTATAAGCGACATCAAAAGATGGGAGAAAAAAATGGCGATGCAAAAACTTTCTGGATGGAGCTAGAAGATGATGGAAAAGTGGACTTCATTTTTGAACAAGTACAAAATGTGCTGCAGTCACTGAAACAAAAGATCAAAGATGGGTCTGCCACCAATAAAGAATACATCCAAGCAATGATTCTAGTGAATGAAGCAACTATAATTAACAGTTCAACATCAATAAAGGGAGCATCACAGAAAGAAGTGAATGCCCAAAGCAGTGATCCTATGCCTGTGACTCAGAAGGAACAGGAAAACAAATCCAATGCATTTCCCTCTACATCATGTGAAAACTCCTTTCCAGAAGACTGTACATTTCTAACAACAGAAAATAAGGAAATTCTCTCTCTTGAAGATAAAGTTGTAGACTTTAGAGAAAAAGACTCATCTTCGAATTTATCTTACCAAAGTCATGACTGCTCTGGTGCTTGTCTGATGAAAATGCCACTGAACTTGAAGGGAGAAAACCCTCTGCAGCTGCCAATCAAATGTCACTTCCAAAGACGACATGCAAAGACAAACTCTCATTCTTCAGCACTCCACGTGAGTTATAAAACCCCTTGTGGAAGGAGTCTACGAAACGTGGAGGAAGTTTTTCGTTACCTGCTTGAGACAGAGTGTAACTTTTTATTTACAGATAACTTTTCTTTCAATACCTATGTTCAGTTGGCTCGGAATTACCCAAAGCAAAAAGAAGTTGTTTCTGATGTGGATATTAGCAATGGAGTGGAATCAGTGCCCATTTCTTTCTGTAATGAAATTGACAGTAGAAAGCTCCCACAGTTTAAGTACAGAAAGACTGTGTGGCCTCGAGCATATAATCTAACCAACTTTTCCAGCATGTTTACTGATTCCTGTGACTGCTCTGAGGGCTGCATAGACATAACAAAATGTGCATGTCTTCAACTGACAGCAAGGAATGCCAAAACTTCCCCCTTGTCAAGTGACAAAATAACCACTGGATATAAATATAAAAGACTACAGAGACAGATTCCTACTGGCATTTATGAATGCAGCCTTTTGTGCAAATGTAATCGACAATTGTGTCAAAACCGAGTTGTCCAACATGGTCCTCAAGTGAGGTTACAGGTGTTCAAAACTGAGCAGAAGGGATGGGGTGTACGCTGTCTAGATGACATTGACAGAGGGACATTTGTTTGCATTTATTCAGGAAGATTACTAAGCAGAGCTAACACTGAAAAATCTTATGGTATTGATGAAAACGGGAGAGATGAGAATACTATGAAAAATATATTTTCAAAAAAGAGGAAATTAGAAGTTGCATGTTCAGATTGTGAAGTTGAAGTTCTCCCATTAGGATTGGAAACACATCCTAGAACTGCTAAAACTGAGAAATGTCCACCAAAGTTCAGTAATAATCCCAAGGAGCTTACTGTGGAAACGAAATATGATAATATTTCAAGAATTCAATATCATTCAGTTATTAGAGATCCTGAATCCAAGACAGCCATTTTTCAACACAATGGGAAAAAAATGGAATTTGTTTCCTCGGAGTCTGTCACTCCAGAAGATAATGATGGATTTAAACCACCCCGAGAGCATCTGAACTCTAAAACCAAGGGAGCACAAAAGGACTCAAGTTCAAACCATGTTGATGAGTTTGAAGATAATCTGCTGATTGAATCAGATGTGATAGATATAACTAAATATAGAGAAGAAACTCCACCAAGGAGCAGATGTAACCAGGCGACCACATTGGATAATCAGAATATTAAAAAGGCAATTGAGGTTCAAATTCAGAAACCCCAAGAGGGACGATCTACAGCATGTCAAAGACAGCAGGTATTTTGTGATGAAGAGTTGCTAAGTGAAACCAAGAATACTTCATCTGATTCTCTAACAAAGTTCAATAAAGGGAATGTGTTTTTATTGGATGCCACAAAAGAAGGAAATGTCGGCCGCTTCCTTAATCATAGTTGTTGCCCAAATCTCTTGGTACAGAATGTTTTTGTAGAAACACACAACAGGAATTTTCCATTGGTGGCATTCTTCACCAACAGGTATGTGAAAGCAAGAACAGAGCTAACATGGGATTATGGCTATGAAGCTGGGACTGTGCCTGAGAAGGAAATCTTCTGCCAATGTGGGGTTAATAAATGTAGAAAAAAAATATTATAAATATGTAACTAACGCCTGTTTGTGAAATTAGCTTATCAGGCTGAAATTAAAGCCATGCAAAAGAAGGTCTAGGTCCATCAAGGAAATTCCCCTCCGTTTTCCTTTGTCATGGGGTTTATGTTTTATTTCAGATTTTATTTGTGTGACTTAGAAATTCCAGGAACACAATTAGGATATTTTCATACACATAGGGTATCTTGTTCACTGCTGTGCTACTTTACATGAGTAGGATGGAAGTGTATATTTTATATGAAATACCACTGTACAATTTATAATTTATTTACAAATTATATATTAAGAGAAACAAATGTCATAACAGAACTCAGCTGTTTCTAATTGCTTTTGTGACTGTTACCTTTTAGTTCATGCCCCCCCAAAGAGCTAAATTTCACATTTTTACCTACAAAATTGATTTTTAATTCCTGGCAAATAATTTACCATTATGAGCTACAAGGTGGGCAACAGCGCCTGAGGATCTAATTTTATGCATATTACTCCCAAGTATTTTAACACTTGTTGGAGAAGCAATATCTGGATCGATAAAACACTGTCCCATCAACCATTTGAGTGGGGAGAGGGAGAAGCTCTTCTGTAAGTAAGATTCTGGCAAGCTCTTTGAAATGAGTCTTCTTTCCCACAGATTTTCTCTACTCTTTCTATACAAACAGATAGGAGAAGAGGGAATAGAAACCTGGAGGAACTTGAATATTTTTGTTCTAGATAGAGATACAGTTACTGAAAAGGAAACCTAGAAAGTAGTCACACGTTGCTTATTTAGGCCAGAAGTAATTGTACTGGGCAAAAATTTCACTTAAAAAACACAAGAAGTCCAGGTATGGTGGCTCAGACCTGTAATCCCAGCACTTTGAGAGGCCGAGGCAGGTGGATTACTTGAGCCTAGGGGTTCAAGACCAGCTTGGGCAACATGTCAAAACCCTGTCTCTACAAAAAATACAAAAATTAGCCTGGCATGATGGCATGTGCCCGTAGTCTCAGCTACTCAGGAGTGAGGTGGGAGGATCATTTGAGCTCAGAAGGTCAAGGCTGCAATGAGACATAATTTCACCATAGTACTTCCAGCCTGGGCAATAGAGCAAGACTCTCTCTCAAAAAAAACAGCACACACACACACACACGAAAACAATTCTGAACTATGAAATCTGAAACAGCCCCTTGGTATCTCCTGGGCATGATTTGCAAATCTTTTTTTTTTACAGAAAAAAGGCAAAGAGTAAGCACTTTGCCATAGGTTACTTGGCCGTGATCATCTATCTAGTGGAAAAGGGGACTGGGAAGCCCAAGCAGACTGGGAAACCAGACAGCTAGGAAAAGGAGCAAAACATAGCCCAGCAACCTACAGATGAAGAAAGTTGAGAAATCCATTTATTCACCATAGAGACGCAGGAATTTCAGGCAATGCACTAAAATGAAATGGGGGAAAAAAGCTTGATCAGTATGGGAACCATTTTTGTGCAAAAGGGAATATTATGGATCAGCCAGTATTTCTTTGAGCTCTGCCTGTGGAGTCCATTTGACCTTTAGAAATATGAGGTATTCTGTCAGTTTTATCTTCTTGGAGAAATTTCTCCTAAAATCTTGATTTGCTTTAGTCTGGACTGGTTCATAGCCATCATCTTCCATCAGTACCCCAGAGATTCACTTTGTCTCTTATGTGGGATCTGTTTCCAGTTAGATGCCATTATTTTCCTTTTCCTTGGTTTACTCTTCCACATATTGGTAAAGCTCTTCCAATAGCTTTTGGAAAGGAAAAATGAAAAGTAAATGTTTTGAATCTCTGTGTGTTTGACAATGTCTTTATTTTACCCTTATACCTGATTGCTGTTTTGGTTGGCAAGGTATAGGATTCTTTAGTGGTCTCCATGCCCAGTTTTGAAGACATCTGCTAGCTTTCAGTGCTGTTGCTGTGGAGTCTGAAAATCTGTCTTCTGGCTTCCAGGGTGACTACTGGAAATTGAATGCCATTCTGTTCCTTCTCTTTTGCATATATAATCCATTTTTATCTCTCTTGAAGCTTATAGGTTTATCTTTGTCTCAATGTTCTGTCCCTGTTAAGAGTCCATTTTCATCCTTTGTACTAGGTGCCTGGTGGGATCATTCCGTCTGAAACTAATGATTTCCCATCTCTTCACTGTTTCTGGAATTCCTGTTTTCCAGATGTTAGACCTCCAGAATTTGATCTCTAATTTTCCTATCTTTTCTCTTAACTTTCAGCTCTGTCTTCTTGCTAGGACCTTTTCCTAGGAGCATTTCTCAATTTAATCTTCCAGTTCATCTGTTGCATTTTATTTTTCTAGTCTCATATTGTCTCATATTTTTAATTTCTAAGAGCTCCCCTTCTCCGAATATTCTTTTTTTTTAATAGCATCCTATTTTGGCTCATGGTTGCAGTATTTTATCTCCTTGAAGATGTTTGTGTGTTTATGTATGTATATGCACACACGTATACATACACATACAGGCATGCATCTCTGTATTCTTTCGGCATAATCTGTGTCCTCCAGGGTTTGTTTCTTTGTTTCCCCTGTATGTTTGTTTTGGTCGTTCACATTATAGGCTTTCCTCAGAGTTAATGGTCTTGGTAGTCTACTCATATTTAAGTGTGGAACACCAAAAAGCTTACTATAAGCTGAGAGTGTGGTAAAGGGCTCTTTGTTTTACTATGACCTACCTGAGCTATCTTGCTGGGGAACACCCTAATGTCAGTCTCTTTATAAAGGGCCTTTCATTTTGGCCTGGCAAGAAATACTCTTTCATCCTCCTGCATGGAGGGCAAAAAAAAATTTAAAAATTGGCTGCTAGGGTCTGTCTGCTCACTTCCCTGTTTTGCAGACCCCACACTCTTCTGCAATTCATTTCATAGTTGTCAAGACTATACAAATTGTCCTTTTTAATGTTCTCTCTTCTGCTATCCCTAGTTGGCAGTCTTCCTCTTTACAACCTGCTGAAAGTGGAAGACCTCCAGTTTTCCTTTAATTCCTCAGCAAACCACCAACTATTATATGTCTTTTTTCCAGAACAACTTATTTTTTAACTATAATTATATGCATTTATGTTAGATTCACTGAAAACCTCATCTTGTATGGTGCTCTGTACCCTATGGGTGCTAAATAAAGGCTTGCTACTGGCAACTGGA
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Sequence Source |
Ensembl |
Keyword |
KW-0025--Alternative splicing KW-0131--Cell cycle KW-0132--Cell division KW-0156--Chromatin regulator KW-0158--Chromosome KW-0181--Complete proteome KW-0217--Developmental protein KW-0479--Metal-binding KW-0489--Methyltransferase KW-0498--Mitosis KW-0539--Nucleus KW-0621--Polymorphism KW-1185--Reference proteome KW-0949--S-adenosyl-L-methionine KW-0808--Transferase KW-0862--Zinc --
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Interpro |
IPR016177--DNA-bd_dom IPR001739--Methyl_CpG_DNA-bd IPR007728--Pre-SET_dom IPR001214--SET_dom
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PROSITE |
PS50982--MBD PS50867--PRE_SET PS50280--SET
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Pfam |
PF01429--MBD PF05033--Pre-SET PF00856--SET
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Gene Ontology |
GO:0005694--C:chromosome GO:0005654--C:nucleoplasm GO:0005634--C:nucleus GO:0003677--F:DNA binding GO:0046974--F:histone methyltransferase activity (H3-K9 specific) GO:0018024--F:histone-lysine N-methyltransferase activity GO:0008270--F:zinc ion binding GO:0051301--P:cell division GO:0007059--P:chromosome segregation GO:0001947--P:heart looping GO:0051567--P:histone H3-K9 methylation GO:0070986--P:left/right axis specification GO:0007067--P:mitotic nuclear division GO:0045892--P:negative regulation of transcription, DNA-templated
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Orthology |
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Created Date |
25-Jun-2016 |