WERAM Information

Tag Content
WERAM ID WERAM-Hos-0149
Ensembl Protein ID ENSP00000275034.3
Uniprot Accession Q8WWQ0; PHIP_HUMAN; A7J992; B2RPK4; Q05CQ9; Q5VVH4; Q66I29; Q69YV1; Q8NBZ5; Q96H52; Q96ME2; Q9H261
Genbank Protein ID NP_060404.3
Protein Name PH-interacting protein
Genbank Nucleotide ID NM_017934.5
Gene Name PHIP;WDR11;ndrp
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000146247.13 ENST00000275034.4 ENSP00000275034.3
Details
Type Family Domain Substrates AA References (PMIDs)
Ac_Reader Bromodomain Bromodomain K 22464331
Status Reviewed
Classification
Type Family E-value Score Start End
Ac_Reader Bromodomain 1.60e-48 164.9 1179 1403
Organism Homo sapiens
NCBI Taxa ID 9606
Functional Description
(View)		 Probable regulator of the insulin and insulin-like growth factor signaling pathways. Stimulates cell proliferation through regulation of cyclin transcription and has an anti-apoptotic activity through AKT1 phosphorylation and activation. Plays a role in the regulation of cell morphology and cytoskeletal organization.
Domain Profile
  Ac_Reader Bromodomain
          BROMO.txt    4 evsepFrepvdpqleipdYydiikePmdLstikerleegnYsspeefvkDvrlifnNakaynenkssv 71  
                         +++++F  pvd+ + +p Y++++  P dLstik+rle++ Y++++ ++  vr i +N +++ne++s +
  ENSP00000275034.3 1179 DIASAFVAPVDL-QAYPMYCTVVAYPTDLSTIKQRLENRFYRRVSSLMWEVRYIEHNTRTFNEPGSPI 1245
                         6789********.8**************************************************9875 PP
          BROMO.txt    2 ehevsepFrepvdpqleipdYydiikePmdLstikerleegnYsspeefvkDvrlifnNakaynenkssvq 72  
                         ++e+sepFr+pvd+ le+pdY+dii++Pmd+ t++e+le+gnY+sp e+ kDvrlif+N+kay++ k s++
  ENSP00000275034.3 1334 QCEDSEPFRQPVDL-LEYPDYRDIIDTPMDFATVRETLEAGNYESPMELCKDVRLIFSNSKAYTPSKRSRI 1403
                         689***********.9***************************************************9875 PP
Protein Sequence
(Fasta)		MSCERKGLSE LRSELYFLIA RFLEDGPCQQ AAQVLIREVA EKELLPRRTD WTGKEHPRTY 60
QNLVKYYRHL APDHLLQICH RLGPLLEQEI PQSVPGVQTL LGAGRQSLLR TNKSCKHVVW 120
KGSALAALHC GRPPESPVNY GSPPSIADTL FSRKLNGKYR LERLVPTAVY QHMKMHKRIL 180
GHLSSVYCVT FDRTGRRIFT GSDDCLVKIW ATDDGRLLAT LRGHAAEISD MAVNYENTMI 240
AAGSCDKMIR VWCLRTCAPL AVLQGHSASI TSLQFSPLCS GSKRYLSSTG ADGTICFWLW 300
DAGTLKINPR PAKFTERPRP GVQMICSSFS AGGMFLATGS TDHIIRVYFF GSGQPEKISE 360
LEFHTDKVDS IQFSNTSNRF VSGSRDGTAR IWQFKRREWK SILLDMATRP AGQNLQGIED 420
KITKMKVTMV AWDRHDNTVI TAVNNMTLKV WNSYTGQLIH VLMGHEDEVF VLEPHPFDPR 480
VLFSAGHDGN VIVWDLARGV KIRSYFNMIE GQGHGAVFDC KCSPDGQHFA CTDSHGHLLI 540
FGFGSSSKYD KIADQMFFHS DYRPLIRDAN NFVLDEQTQQ APHLMPPPFL VDVDGNPHPS 600
RYQRLVPGRE NCREEQLIPQ MGVTSSGLNQ VLSQQANQEI SPLDSMIQRL QQEQDLRRSG 660
EAVISNTSRL SRGSISSTSE VHSPPNVGLR RSGQIEGVRQ MHSNAPRSEI ATERDLVAWS 720
RRVVVPELSA GVASRQEEWR TAKGEEEIKT YRSEEKRKHL TVPKENKIPT VSKNHAHEHF 780
LDLGESKKQQ TNQHNYRTRS ALEETPRPSE EIENGSSSSD EGEVVAVSGG TSEEEERAWH 840
SDGSSSDYSS DYSDWTADAG INLQPPKKVP KNKTKKAESS SDEEEESEKQ KQKQIKKEKK 900
KVNEEKDGPI SPKKKKPKER KQKRLAVGEL TENGLTLEEW LPSTWITDTI PRRCPFVPQM 960
GDEVYYFRQG HEAYVEMARK NKIYSINPKK QPWHKMELRE QELMKIVGIK YEVGLPTLCC 1020
LKLAFLDPDT GKLTGGSFTM KYHDMPDVID FLVLRQQFDD AKYRRWNIGD RFRSVIDDAW 1080
WFGTIESQEP LQLEYPDSLF QCYNVCWDNG DTEKMSPWDM ELIPNNAVFP EELGTSVPLT 1140
DGECRSLIYK PLDGEWGTNP RDEECERIVA GINQLMTLDI ASAFVAPVDL QAYPMYCTVV 1200
AYPTDLSTIK QRLENRFYRR VSSLMWEVRY IEHNTRTFNE PGSPIVKSAK FVTDLLLHFI 1260
KDQTCYNIIP LYNSMKKKVL SDSEDEEKDA DVPGTSTRKR KDHQPRRRLR NRAQSYDIQA 1320
WKKQCEELLN LIFQCEDSEP FRQPVDLLEY PDYRDIIDTP MDFATVRETL EAGNYESPME 1380
LCKDVRLIFS NSKAYTPSKR SRIYSMSLRL SAFFEEHISS VLSDYKSALR FHKRNTITKR 1440
RKKRNRSSSV SSSAASSPER KKRILKPQLK SESSTSAFST PTRSIPPRHN AAQINGKTES 1500
SSVVRTRSNR VVVDPVVTEQ PSTSSAAKTF ITKANASAIP GKTILENSVK HSKALNTLSS 1560
PGQSSFSHGT RNNSAKENME KEKPVKRKMK SSVLPKASTL SKSSAVIEQG DCKNNALVPG 1620
TIQVNGHGGQ PSKLVKRGPG RKPKVEVNTN SGEIIHKKRG RKPKKLQYAK PEDLEQNNVH 1680
PIRDEVLPSS TCNFLSETNN VKEDLLQKKN RGGRKPKRKM KTQKLDADLL VPASVKVLRR 1740
SNRKKIDDPI DEEEEFEELK GSEPHMRTRN QGRRTAFYNE DDSEEEQRQL LFEDTSLTFG 1800
TSSRGRVRKL TEKAKANLIG W 1821
Nucleotide Sequence
(Fasta)		GTTGTTTCCT CCTCCTCCTC CTCCGCCTCC GCCGCCGTTG CTTGAATGGT GGAGCCGAAG 60
CTCGGCTCGT GAACACACAC TGACAGCTAT AGGGCAGGCG GCGGCACCGT CCCCGCTTCC 120
CCTCGGCGGC GGGGTGTCCC GTCGGCGGCC CTGAAGTGAC CCATAAACAT GTCTTGTGAG 180
AGGAAAGGCC TCTCGGAGCT GCGATCGGAG CTCTACTTCC TCATCGCCCG GTTCCTGGAA 240
GATGGACCCT GTCAGCAGGC GGCTCAGGTG CTGATCCGCG AGGTGGCCGA GAAGGAGCTG 300
CTGCCCCGGC GCACCGACTG GACCGGGAAG GAGCATCCCA GGACCTACCA GAATCTGGTG 360
AAGTATTACA GACACTTAGC ACCTGATCAC TTGCTGCAAA TATGTCATCG ACTAGGACCT 420
CTTCTTGAAC AAGAAATTCC TCAAAGTGTT CCTGGAGTAC AAACTTTATT AGGAGCTGGA 480
AGACAGTCTT TACTACGCAC AAATAAAAGC TGCAAGCATG TTGTGTGGAA AGGATCTGCT 540
CTGGCTGCGT TGCACTGTGG AAGACCACCT GAGTCACCAG TTAACTATGG TAGCCCACCC 600
AGCATTGCGG ATACTCTGTT TTCAAGGAAG CTGAATGGGA AATACAGACT TGAGCGACTT 660
GTTCCAACTG CAGTGTATCA GCACATGAAA ATGCATAAAC GAATTCTTGG ACACTTGTCA 720
TCTGTGTACT GTGTAACTTT TGATCGAACT GGCAGACGGA TATTTACTGG TTCTGATGAC 780
TGTCTTGTGA AAATATGGGC AACAGATGAT GGGAGGTTGT TAGCTACCTT AAGAGGACAT 840
GCTGCTGAAA TATCAGACAT GGCTGTAAAC TATGAGAATA CCATGATAGC AGCTGGAAGT 900
TGTGATAAAA TGATCCGAGT CTGGTGTCTT CGAACCTGTG CACCTTTGGC TGTTCTTCAG 960
GGCCATAGTG CATCTATTAC ATCACTACAG TTCTCACCAT TGTGCAGTGG CTCAAAGAGA 1020
TATCTATCTT CTACTGGGGC AGATGGCACT ATTTGTTTTT GGCTCTGGGA TGCTGGAACC 1080
CTTAAAATAA ACCCAAGACC TGCAAAATTT ACAGAGCGCC CTCGGCCTGG AGTTCAAATG 1140
ATCTGTTCTT CTTTTAGTGC TGGTGGAATG TTTCTGGCGA CGGGAAGCAC AGATCATATT 1200
ATTCGGGTTT ATTTTTTTGG ATCAGGTCAG CCAGAGAAAA TATCAGAATT GGAGTTTCAT 1260
ACTGACAAAG TTGACAGTAT CCAGTTTTCC AACACTAGTA ACAGGTTTGT AAGTGGCAGT 1320
CGTGATGGGA CAGCACGTAT TTGGCAATTT AAACGAAGAG AGTGGAAGAG CATTTTGTTG 1380
GATATGGCTA CTCGTCCAGC AGGCCAAAAC CTTCAAGGAA TAGAAGATAA AATCACAAAA 1440
ATGAAGGTTA CTATGGTAGC TTGGGATCGA CATGACAATA CAGTTATAAC TGCAGTTAAT 1500
AACATGACTC TGAAAGTTTG GAATTCTTAC ACTGGTCAAC TAATTCATGT CCTGATGGGT 1560
CATGAAGATG AGGTATTTGT TCTTGAACCA CACCCGTTCG ATCCTAGAGT TCTCTTTTCT 1620
GCTGGTCATG ATGGAAACGT GATAGTGTGG GATCTGGCAA GAGGAGTCAA AATACGATCT 1680
TATTTCAATA TGATTGAAGG CCAAGGACAT GGCGCAGTAT TTGACTGCAA ATGCTCTCCT 1740
GATGGTCAGC ATTTTGCATG CACAGACTCT CATGGACATC TTTTAATTTT TGGCTTTGGG 1800
TCCAGTAGCA AATATGACAA GATAGCAGAT CAGATGTTCT TTCATAGTGA TTATCGGCCA 1860
CTTATTCGTG ATGCCAACAA TTTTGTATTA GATGAACAGA CTCAGCAAGC ACCTCATCTT 1920
ATGCCTCCCC CTTTTTTGGT TGATGTTGAT GGTAACCCTC ATCCATCAAG ATATCAAAGA 1980
TTAGTTCCTG GCCGTGAAAA TTGCAGGGAG GAGCAACTCA TCCCTCAGAT GGGAGTAACT 2040
TCCTCAGGAC TGAATCAAGT TTTAAGTCAG CAAGCAAACC AGGAGATCAG CCCACTGGAC 2100
AGCATGATTC AAAGACTACA ACAGGAGCAA GACCTGAGAC GTTCTGGTGA AGCAGTTATC 2160
AGTAATACCA GCCGTTTAAG TAGAGGCTCC ATAAGTTCTA CCTCAGAGGT TCATTCACCA 2220
CCAAACGTAG GACTAAGACG TAGTGGACAA ATTGAAGGTG TACGGCAAAT GCACAGCAAC 2280
GCACCAAGAA GTGAAATAGC CACAGAGCGG GATCTGGTAG CTTGGAGTCG AAGGGTGGTA 2340
GTACCCGAGC TATCAGCTGG TGTAGCCAGT AGGCAAGAAG AATGGAGAAC TGCAAAGGGA 2400
GAAGAAGAAA TAAAGACTTA CAGGTCAGAA GAGAAAAGAA AACACTTAAC TGTTCCAAAA 2460
GAGAATAAAA TACCCACTGT CTCAAAGAAT CATGCTCATG AGCATTTCCT GGATCTTGGA 2520
GAATCCAAAA AGCAACAGAC AAATCAACAC AATTATCGTA CAAGATCTGC ATTGGAAGAG 2580
ACTCCTAGAC CCTCAGAAGA GATAGAAAAT GGCAGTAGTT CTTCAGATGA AGGCGAAGTA 2640
GTTGCTGTCA GTGGTGGAAC ATCCGAAGAA GAAGAGAGAG CATGGCACAG TGATGGCAGT 2700
TCTAGTGACT ACTCCAGTGA TTACTCTGAC TGGACAGCAG ATGCAGGAAT TAATCTGCAG 2760
CCACCAAAGA AAGTTCCTAA GAATAAAACC AAGAAAGCAG AAAGCAGTTC AGATGAAGAA 2820
GAAGAATCTG AAAAACAGAA GCAAAAACAG ATTAAAAAGG AAAAGAAAAA AGTAAATGAA 2880
GAAAAAGATG GACCAATATC ACCAAAGAAA AAGAAGCCCA AAGAAAGAAA ACAAAAGAGA 2940
TTGGCTGTGG GAGAACTAAC TGAAAATGGT TTGACATTAG AAGAATGGTT GCCATCAACA 3000
TGGATTACAG ATACCATTCC CCGAAGATGT CCATTTGTGC CACAGATGGG TGATGAGGTT 3060
TATTATTTCC GACAAGGACA TGAAGCCTAT GTCGAAATGG CCCGGAAAAA TAAAATATAT 3120
AGTATCAATC CCAAAAAACA ACCATGGCAT AAAATGGAGC TACGGGAACA AGAACTTATG 3180
AAAATAGTTG GCATAAAGTA TGAAGTGGGA TTACCTACCC TTTGCTGCCT TAAACTTGCT 3240
TTTCTAGATC CTGATACTGG TAAACTGACT GGCGGATCAT TTACCATGAA ATACCATGAT 3300
ATGCCTGACG TTATAGATTT CCTAGTCTTG AGACAACAAT TTGATGATGC AAAATACAGG 3360
CGATGGAATA TAGGTGACCG CTTCAGGTCT GTCATAGATG ATGCCTGGTG GTTTGGAACA 3420
ATCGAAAGCC AGGAACCTCT TCAACTTGAG TACCCTGATA GTCTGTTTCA ATGCTACAAT 3480
GTTTGCTGGG ACAATGGAGA TACAGAAAAG ATGAGTCCTT GGGATATGGA GCTTATACCT 3540
AATAATGCTG TATTTCCTGA AGAACTAGGT ACCAGTGTTC CTTTAACTGA TGGTGAGTGC 3600
AGATCACTAA TCTATAAACC TCTTGATGGA GAATGGGGTA CCAATCCCAG GGATGAAGAA 3660
TGTGAAAGAA TTGTGGCAGG AATAAACCAG TTGATGACAC TAGATATTGC CTCAGCATTT 3720
GTGGCCCCCG TGGATCTGCA AGCCTATCCC ATGTATTGCA CAGTAGTGGC ATATCCAACG 3780
GATCTAAGTA CAATTAAACA AAGACTGGAA AACAGGTTTT ACAGGCGGGT TTCTTCCCTA 3840
ATGTGGGAAG TTCGATATAT AGAGCATAAT ACACGAACAT TTAATGAGCC TGGAAGCCCT 3900
ATTGTGAAAT CTGCTAAATT CGTGACTGAT CTTCTTCTAC ATTTTATAAA GGATCAGACT 3960
TGTTATAACA TAATTCCACT TTATAATTCA ATGAAGAAGA AAGTTTTGTC TGATTCTGAG 4020
GATGAAGAGA AAGATGCTGA TGTGCCAGGA ACTTCTACTC GAAAAAGGAA GGACCATCAG 4080
CCTAGAAGAA GATTACGTAA TAGAGCCCAG TCTTACGATA TTCAAGCATG GAAGAAACAG 4140
TGTGAAGAAT TGTTAAATCT CATATTTCAA TGTGAAGATT CAGAGCCTTT CCGTCAGCCG 4200
GTAGATCTCC TTGAATATCC AGACTACAGA GACATCATTG ACACTCCAAT GGATTTTGCT 4260
ACCGTTAGAG AAACTTTAGA GGCTGGGAAT TATGAGTCAC CAATGGAGTT ATGTAAAGAT 4320
GTCAGACTTA TTTTCAGTAA TTCCAAAGCA TATACACCAA GCAAAAGATC AAGGATTTAC 4380
AGCATGAGTT TGCGCCTGTC TGCTTTCTTT GAAGAACACA TTAGTTCAGT TTTATCAGAT 4440
TATAAATCTG CTCTTCGTTT TCATAAAAGA AATACCATAA CCAAAAGGAG GAAGAAAAGA 4500
AACAGAAGCA GCTCTGTTTC CAGTAGTGCT GCATCAAGCC CTGAAAGGAA AAAAAGGATC 4560
TTAAAACCCC AGCTAAAATC AGAAAGCTCT ACCTCTGCAT TCTCTACACC TACACGATCA 4620
ATACCGCCAA GACACAATGC TGCTCAGATA AACGGTAAAA CAGAATCTAG TTCTGTGGTT 4680
CGAACCAGAA GCAACCGAGT GGTTGTAGAT CCAGTTGTCA CTGAGCAACC ATCTACTTCT 4740
TCAGCTGCAA AGACTTTTAT TACAAAAGCT AATGCATCTG CAATACCAGG GAAAACAATA 4800
CTAGAGAATT CTGTGAAACA TTCCAAAGCT TTGAATACTC TTTCCAGTCC TGGTCAATCC 4860
AGTTTTAGTC ATGGCACTAG GAATAATTCT GCAAAAGAAA ACATGGAAAA GGAAAAGCCA 4920
GTCAAACGTA AAATGAAGTC ATCTGTACTC CCAAAGGCGT CCACTCTTTC AAAGTCATCA 4980
GCTGTCATTG AGCAAGGAGA TTGTAAGAAC AACGCTCTTG TACCAGGAAC CATTCAAGTA 5040
AATGGCCATG GAGGACAGCC ATCAAAACTT GTGAAGAGGG GACCTGGAAG GAAACCTAAA 5100
GTAGAAGTTA ATACCAATAG TGGTGAAATT ATACACAAGA AAAGGGGTAG AAAGCCCAAA 5160
AAGCTACAGT ATGCAAAGCC AGAAGATTTA GAGCAAAATA ATGTGCATCC CATCAGAGAT 5220
GAAGTACTTC CTTCTTCAAC ATGCAATTTT CTTTCTGAAA CTAATAATGT AAAGGAAGAT 5280
TTGTTACAGA AAAAGAATCG TGGAGGTAGG AAGCCCAAAA GGAAGATGAA GACACAAAAA 5340
TTAGATGCAG ATCTCCTAGT CCCTGCAAGT GTCAAAGTGT TAAGGAGAAG TAACCGAAAA 5400
AAGATAGATG ATCCTATAGA TGAGGAAGAA GAGTTTGAAG AACTCAAAGG CTCTGAACCC 5460
CACATGAGAA CTAGAAATCA AGGTCGAAGG ACAGCTTTCT ATAATGAGGA TGACTCTGAA 5520
GAGGAGCAAA GGCAGCTGTT GTTCGAAGAC ACCTCTTTAA CTTTTGGAAC TTCTAGTAGA 5580
GGACGAGTCC GAAAGTTGAC TGAAAAAGCA AAAGCTAATT TAATTGGTTG GTAACTTGTA 5640
CCAAAATATT TTACTTCAAA ATCTATAAAG CAGGTACAGT TAAGGAATAA GTAGAACTAA 5700
GGCTTCTGCT TCCTTGCTGC TGTGGTGGAG TAGGGAATGT TATGATTTGA TTTGCAAAAA 5760
AAAAAAAAAA AAAAAAAACA AACTTACGAG ACACTTCACT TCTTTAAATG AATATATATA 5820
TATATATATA AATATATACA TATATATTTT AAATGTTTGC TATTTATTGC CCTTAGATAG 5880
GTTATGCATT TTCACATTCA TTTCATTCAC TGTTTGAAAC GAAAGAAATT GATCTATAAT 5940
GAATTCCTGA TTTATTTATA GAAAAGACAA TTCTGCTACA CTCTTTAGGA GCATAATATT 6000
CCTAGTGATA GAGCATTTCA TGTTAAAATG AATTATTTTT GACCAAGTGA GGTACATTTC 6060
TATTGATACA AGTCATGCCC CTAAAAGATA GATGTTATAC AGAGTAGCAG TGAATTAAGA 6120
AATGTTTCCT CTAAAAGATA AATATAAAAT TTCCACCATT TGATACCCTA AACAGTTTAA 6180
TTTTAATTAT AGAATGTTCA TCTACAAAGT ATCTAGAGGA GGCTTTTGCT TTATTCCATT 6240
TCTGCCAAAC AAGAGAAAAT GTACTGATGA AGGGAAACAT ATCCACATTG GAAAACATTT 6300
GACTGTCTAA TTTTTCAGAC CTTGATTCTT ATATCACTCA ATCTCTGTTT ATTGTGCCAA 6360
AGACTGAGAA TCAGTGCAGT GGAAAGCCTG TTTTTGACGT CAGGACAGCA TACACTTTTC 6420
AATATTGGAA AGGCTATATA TTCTAAAGAG CAAGTTATTA AAGAGTTATG CTGAGATATA 6480
TCTTTTTTTG GTACTAATAG AAAATAATGC ACTGGTGGGT CCTTTGACAG AGATGTTCTA 6540
GAGGAAATGT TTAAGTGGTT AAAGGATTCA AGGAAAATAC AGGAAAAAAG GTATGGGATT 6600
TGATGTTTAC TTGTTGATCT GGATTAATGT CATTTCTAAA CTTTAGACAT ATCTAATAGC 6660
CTAAAATGAC TTACAAAGAA ACGTGTCTGT GTGTGTATGT GTATATATTG ATAAATGGGT 6720
ATAATTAAAT ATATATACAA ACACATACTT ATATACTATT ACCCAGGTAT AAATTCTTTT 6780
TTCAGGATTT TTTAGATAGC AGTAGAATAA AAATAATTTT AAAATGTCAT ACTTTATAGT 6840
TTAATTTTAA GGGGGAAATT GGTTATTTTC AATTATTAAA GGTTAAAATA GGCCAAATCA 6900
CTTTTTATGC AATCATGTTT TATACAGTGG TCTCATTGCA CATTGTGTTT TTTCTGCACT 6960
TTTTACGGTA TCCTTATCAT GCTGGTATGT CAATATACAC CCTAAAGAAA AACTCCATTT 7020
AATGATTGTG CCTTGTATTC TATTATTTTT TGCATCATTA GTAAAATTAA GTTGTCTATT 7080
GTAAATGATA ACTATATGAC TTAGGAGAAT GTATTGCTAT ATGTACTGCT ATGGAAAAGG 7140
AAAGCAGTTA TTTATTTGTT TATGGTACAG TTAGTTATTT TATACCTTAA AAACCAACAT 7200
ACTTACCATT TCTATTGTTT AAAAATTACT GTCCATTTTT TTAAAAATTT AAAGAATGTA 7260
GTATTTTCTG AGGACTGGTA TGGTACAAAA ATGTAATCAA AATTTTCAGA TACTACATTT 7320
TTAAAAAGTG AGGATGGGGA AAATATGTAT CAGCATGACC CTGATGTAGA AAAATAAAGT 7380
CTGCAATTGA ACCTTGGCAA AATACATTAC ATAATTATTT CTGATAAGGA TAAATATTAG 7440
CTGTCATTTA ACTGTCGTGA AGAATGAAAA AGTGATACAT TTGGGCTTTT TAGATCATTT 7500
GTAACTAAAT TTGTACAGAA ATTCTCCTGT GAAATTAAGT AAACCATTTT CCAGATCTTG 7560
ACTGCATTGC TGAGATTTTG CAGTTGAAAA ATAATTTCAA ATTTTTCAGG TTTTTTGTAT 7620
ATTTATTTTT TTCTAACAAA TATATTTAAC TATAAAATTA AAATTCAGTA GTTAAACTCT 7680
TCATAATGCA GAAATGGATG GCTTGATTGT ATAGAAAAAT GAGTCTTTCA GTTACACCAT 7740
TCTTGAAAAT AATAGTGTAT GTTTGAAATT TGTCATTAAT TAGTTGCTTT TGAAGGCAAT 7800
CTATTTGAAA TATGTAATTT CCTGATGTTA TCTGCATTGT GTTAAGAAAA AAATAATAGG 7860
CTATAAAATC AATTTTTGTA AAAAAAATGT ACAGTTTTAA GTTGTGTACA GAAAAAGGAA 7920
GAGCGTACAC AGTCTTAGAG TGGAATATAC CTCTAGTACA GTGTATGTGT TAATTCCAAC 7980
TCAAGCAAAG AAATGAGTAT TTACCATCTT TCCTATAACA TGTAAATGTA TTATTCCTGT 8040
TCTACAGACA CTGTATATTT ATGACCTTAT TTGGACATTA TTAGACACTG GTTTCTTAGT 8100
AAAGCACAGT AACTTGGATC AGATTCTTTG TAACCGAAAC ACTTAAACAT GTATTAGTAA 8160
TACCAATATA TTTAGATTTT ATATTTTTAT AATTTAGCTT CTATGCATTA CAGAAGTTGA 8220
ATTAAGAAAT TTAAGTCATC ACCATATTTT TGTTTTCTTT ACCACTTGGG AAAATAATCC 8280
TCTTTGAGGC AGTAACACTA TGTATGTACT GTTAATAGGC CAGAAAGAAA TATTGGCAGT 8340
TGTCTTAGGT AAGCAATAAA AACATCTCCA ATTTACTGAA AGTTCAGAAA TATAACTCTT 8400
ACATGCATGG AAAGTGTAAA CCAATTTAGG TATTTCTAAG TACCCAACCC TAGTATTCTC 8460
TCCCTCAACT CCAACATTCT CAAGTCCCAG ATGAAAAGTT TCAGTGGAGC ATTAGTTTAA 8520
ATATTTAGTC TAATCAGAGA CTCACAGCCC TGGGCAATAG ATACATAGCT TTTTAAAATT 8580
TTATCCTTTG TGACCTGCTA TAGTGGCATT GGACTATTTT CTGCATGTAT TATAAACTAA 8640
AGATTGGCCT TATTTCAATT GTTTTTATTG CACAACTTCA CTACAAATTT AAAGACTGCT 8700
GGCATTATTA TAAAACTGTC TTCCTCCAAT CCAAGTAAAT AAGTATGTGG AATATTTGTG 8760
AGCTGGATTA GGTAACATCT GAGACTTGGG ATTGACTAAA TTTAGTTATC ACTTGGAAAT 8820
GAATTACATA AGATACAGTA ATCAGAGAAA ATATCTTTAT GCAGCATGTA TGTTAACATC 8880
TAGAACTGTC CCTCATCTGC AGTGCAGTAG AGGAATCAGA CATTTTAAGA AATGTATTCA 8940
AATATTTTTA TCTTATATGT TAGCAGCATT TACATGTTTT CAGATATGAT TTGTAATATA 9000
AATTAATTTC TCCAGTTAAC AATGTTTACT TCAATTCTGA CATTCCATTT TATACATATA 9060
TACCTACTGT ATATCTCTCT CAAATGTCAG CTAGAAGCAA CTTTTTCAGT TTTCTATCTA 9120
ATGAAAACGG ATATATTCTG AATGTTTTTG TTACCTGAAA TTTATTTTTG AGTAGGTTGA 9180
AAGGACCAAG ATACTTGAGT GATTAAAGGA CTGTAAGTGT TCTGCTTATA TGCAGGAGTT 9240
ACATGATTTT AAAAGTCATA ATAGGGGAAG TAGTTTTATC ATCTGATTAC TCCTATTAAC 9300
CTAAAAAGTA TTTCTAACAT AACAGATTGA GCAGTGGTTT TGTTACACTT AGGCAAGAAT 9360
TTATTTTCCC ATTAAAATTT GAAAAATACA CTTTTCTTTG CTTCTACCCT TGCAGTTTCC 9420
CTTAGTTCCC CTAATTTCCA AGTGATCTGA ACTAAAATTA ATATTACATT TACTAAGAAA 9480
CTATTTTTGT TAATTATACT GAGCAAAGTT TGCTCCAAAT GAAAAGTCAT TACGAACTAT 9540
GTATAGTACC CAAGAAAAGG TCAAATTGAG TCAGAAGACT GTAAGTACCA CTTTTGGCGC 9600
TCCAGAGATA AACCTTGTAC ACACTGCAGT AGAACAGTGA GTAGAAAATA TGAGCTATAA 9660
ATAGATATTA TTTTTAGTTT TGATAGCTCT GTGTTGAAAT ACTTTTTTAA TGCAGATAAA 9720
AATTATCAGG AAATTAACCT TATGGCACAG ACCAAATACT TAGTGCATGG CTGAGTTTCT 9780
ACAATTCAAG GAGCCAAGAA AATAGGTTCA AGATGGAATA TAGTACATGC ATATAAGGCA 9840
GATGCACACA TGCTGGTTAC TTTAAGATTG TGTGTGTTGA TTAGTCACAA TGATAGACTA 9900
TAACATGAGA CAATACAAAG TTACATTTTT GGACCATATT AAAACTGCAA GAAGACAGGG 9960
GTCTTACTGA AGATCTTTTA GAAAACTTAA ATCCTGTCAC AGGATATTTA GACATGTGTA 10020
GAATGTAGCT CAATTTTTAA AAAGTAACTG ACCTAGAGGG TGAAAGTTGA AACTGACACA 10080
TTTTCAAATT AAGATTATGC TTATTTTGTA CAGAAAACAA TGTTTAAACA CAAGCAGATC 10140
TGTTGTATGT AATAAGTAAC ACAGAGTTTT AAAACAAATT AATTATTTAG CTTTATTGAA 10200
GTTTGTTTTT TTCCTTCCGA ACCTGGAGTA TCATATTATA AACAGCAGTT TCACACCAGA 10260
ATAGCAGTGC CCTTTCTTTT TGTACATACT GATTGGACCT TTCTTTACTG TTACGTGGAC 10320
ACTTTCTATG TTAGTTTTGA TGCATAATTC TTTGAATCCT TTTATACAAA CTAGAATGTA 10380
TGTGTAAGAA TACCTGTCCC TGCAATGTAG TAACTACAAA CTTATTTTTA AATAAATAGA 10440
AAACTTGTTT TTCTAAGCTA 10461
Sequence Source Ensembl
Keyword

KW-0002--3D-structure
KW-0007--Acetylation
KW-0103--Bromodomain
KW-0181--Complete proteome
KW-1017--Isopeptide bond
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0677--Repeat
KW-0832--Ubl conjugation
KW-0853--WD repeat
--
Interpro

IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR028738--PHIP
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF00439--Bromodomain
PF00400--WD40
Gene Ontology

GO:0070062--C:extracellular exosome
GO:0005634--C:nucleus
GO:0005158--F:insulin receptor binding
GO:0070577--F:lysine-acetylated histone binding
GO:0007010--P:cytoskeleton organization
GO:0008286--P:insulin receptor signaling pathway
GO:0043066--P:negative regulation of apoptotic process
GO:2001237--P:negative regulation of extrinsic apoptotic signaling pathway
GO:0008284--P:positive regulation of cell proliferation
GO:0043568--P:positive regulation of insulin-like growth factor receptor signaling pathway
GO:0045840--P:positive regulation of mitotic nuclear division
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0022604--P:regulation of cell morphogenesis
GO:0008360--P:regulation of cell shape
GO:0001932--P:regulation of protein phosphorylation
Orthology
WERAM ID Ensembl Protein ID Species Identity E-value Score
WERAM-Poa-0151 ENSPPYP00000018794.1 Pongo abelii 100 0.0 3405
WERAM-Chs-0205 ENSCSAP00000013465.1 Chlorocebus sabaeus 99 0.0 3392
WERAM-Paa-0174 ENSPANP00000005100.1 Papio anubis 99 0.0 3391
WERAM-Nol-0135 ENSNLEP00000015026.1 Nomascus leucogenys 99 0.0 3355
WERAM-Gog-0017 ENSGGOP00000001684.2 Gorilla gorilla 100 0.0 3321
WERAM-Pat-0153 ENSPTRP00000031388.3 Pan troglodytes 100 0.0 3306
WERAM-Caf-0035 ENSCAFP00000004153.3 Canis familiaris 96 0.0 3284
WERAM-Dan-0114 ENSDNOP00000014552.3 Dasypus novemcinctus 95 0.0 3282
WERAM-Mum-0127 ENSMUSP00000034787.5 Mus musculus 95 0.0 3272
WERAM-Mam-0164 ENSMMUP00000022610.2 Macaca mulatta 99 0.0 3268
WERAM-Aim-0144 ENSAMEP00000013622.1 Ailuropoda melanoleuca 96 0.0 3239
WERAM-Eqc-0068 ENSECAP00000009059.1 Equus caballus 97 0.0 3209
WERAM-Loa-0012 ENSLAFP00000000673.3 Loxodonta africana 96 0.0 3175
WERAM-Bot-0194 ENSBTAP00000034268.2 Bos taurus 96 0.0 3171
WERAM-Otg-0040 ENSOGAP00000002620.2 Otolemur garnettii 97 0.0 3152
WERAM-Sus-0029 ENSSSCP00000004824.2 Sus scrofa 93 0.0 3146
WERAM-Tut-0004 ENSTTRP00000000220.1 Tursiops truncatus 91 0.0 3096
WERAM-Ran-0053 ENSRNOP00000011864.6 Rattus norvegicus 93 0.0 3096
WERAM-Fec-0105 ENSFCAP00000008896.3 Felis catus 97 0.0 3074
WERAM-Sah-0091 ENSSHAP00000010660.1 Sarcophilus harrisii 91 0.0 3071
WERAM-Vip-0055 ENSVPAP00000005245.1 Vicugna pacos 94 0.0 3048
WERAM-Mup-0211 ENSMPUP00000017978.1 Mustela putorius furo 96 0.0 2966
WERAM-Tag-0154 ENSTGUP00000012976.1 Taeniopygia guttata 86 0.0 2956
WERAM-Ova-0066 ENSOARP00000007402.1 Ovis aries 96 0.0 2944
WERAM-Fia-0042 ENSFALP00000002760.1 Ficedula albicollis 85 0.0 2918
WERAM-Orc-0159 ENSOCUP00000014110.3 Oryctolagus cuniculus 95 0.0 2895
WERAM-Anp-0019 ENSAPLP00000003113.1 Anas platyrhynchos 86 0.0 2872
WERAM-Gaga-0144 ENSGALP00000025563.4 Gallus gallus 85 0.0 2638
WERAM-Tas-0114 ENSTSYP00000011675.1 Tarsius syrichta 85 0.0 2622
WERAM-Xet-0079 ENSXETP00000025715.4 Xenopus tropicalis 76 0.0 2616
WERAM-Mod-0173 ENSMODP00000026231.3 Monodelphis domestica 96 0.0 1704
WERAM-Myl-0059 ENSMLUP00000004914.2 Myotis lucifugus 98 0.0 1650
WERAM-Anc-0040 ENSACAP00000004649.3 Anolis carolinensis 91 0.0 1608
WERAM-Ptv-0063 ENSPVAP00000006428.1 Pteropus vampyrus 95 0.0 1603
WERAM-Cap-0084 ENSCPOP00000006044.2 Cavia porcellus 98 0.0 1599
WERAM-Ora-0009 ENSOANP00000001488.1 Ornithorhynchus anatinus 94 0.0 1597
WERAM-Soa-0067 ENSSARP00000006747.1 Sorex araneus 92 0.0 1535
WERAM-Tub-0112 ENSTBEP00000012496.1 Tupaia belangeri 93 0.0 1504
WERAM-Lac-0024 ENSLACP00000004089.1 Latimeria chalumnae 84 0.0 1498
WERAM-Prc-0035 ENSPCAP00000003322.1 Procavia capensis 87 0.0 1477
WERAM-Dio-0125 ENSDORP00000011981.1 Dipodomys ordii 85 0.0 1440
WERAM-Leo-0168 ENSLOCP00000020035.1 Lepisosteus oculatus 81 0.0 1430
WERAM-Ere-0011 ENSEEUP00000000574.1 Erinaceus europaeus 85 0.0 1412
WERAM-Mim-0002 ENSMICP00000000123.1 Microcebus murinus 85 0.0 1391
WERAM-Dar-0037 ENSDARP00000018130.6 Danio rerio 78 0.0 1364
WERAM-Ten-0114 ENSTNIP00000012568.1 Tetraodon nigroviridis 76 0.0 1336
WERAM-Orn-0014 ENSONIP00000001313.1 Oreochromis niloticus 76 0.0 1335
WERAM-Orla-0107 ENSORLP00000012981.1 Oryzias latipes 76 0.0 1335
WERAM-Tar-0005 ENSTRUP00000001375.1 Takifugu rubripes 76 0.0 1326
WERAM-Pof-0006 ENSPFOP00000000952.2 Poecilia formosa 75 0.0 1316
WERAM-Ict-0146 ENSSTOP00000020521.1 Ictidomys tridecemlineatus 94 0.0 1229
WERAM-Ect-0008 ENSETEP00000000455.1 Echinops telfairi 84 0.0 1147
WERAM-Pes-0083 ENSPSIP00000010615.1 Pelodiscus sinensis 66 0.0 1088
WERAM-Asm-0127 ENSAMXP00000012597.1 Astyanax mexicanus 61 0.0 1081
WERAM-Meg-0147 ENSMGAP00000015414.2 Meleagris gallopavo 61 0.0 1077
WERAM-Caj-0153 ENSCJAP00000000500.2 Callithrix jacchus 61 0.0 1068
WERAM-Xim-0009 ENSXMAP00000001252.1 Xiphophorus maculatus 61 0.0 1065
WERAM-Gaa-0217 ENSGACP00000026878.2 Gasterosteus aculeatus 59 0.0 1007
WERAM-Chh-0039 ENSCHOP00000004772.1 Choloepus hoffmanni 83 0.0 866
WERAM-Mae-0125 ENSMEUP00000012711.1 Macropus eugenii 58 0.0 850
WERAM-Ocp-0001 ENSOPRP00000000332.1 Ochotona princeps 80 0.0 768
WERAM-Gam-0106 ENSGMOP00000011171.1 Gadus morhua 68 0.0 709
WERAM-Drm-0016 FBpp0083988 Drosophila melanogaster 51 0.0 668
WERAM-Cii-0032 ENSCINP00000012790.3 Ciona intestinalis 38 5e-104 377
WERAM-Pem-0055 ENSPMAP00000006254.1 Petromyzon marinus 63 1e-90 333
WERAM-Viv-0028 VIT_05s0077g01160.t01 Vitis vinifera 32 5e-81 301
WERAM-Brr-0054 Bra010036.1-P Brassica rapa 33 9e-81 300
WERAM-Bro-0130 Bo7g092740.1 Brassica oleracea 33 4e-80 298
WERAM-Glm-0194 GLYMA15G15220.2 Glycine max 32 7e-80 297
WERAM-Art-0139 AT5G49430.1 Arabidopsis thaliana 33 3e-79 295
WERAM-Tra-0184 Traes_5AS_1F04E10C7.2 Triticum aestivum 32 9e-79 293
WERAM-Arl-0118 fgenesh2_kg.8__ 815__ AT5G49430.1 Arabidopsis lyrata 33 2e-78 292
WERAM-Prp-0095 EMJ23094 Prunus persica 32 2e-78 292
WERAM-Mua-0028 GSMUA_Achr11P20690_001 Musa acuminata 31 8e-78 290
WERAM-Pot-0117 POPTR_0010s15260.1 Populus trichocarpa 33 8e-77 287
WERAM-Amt-0066 ERN16745 Amborella trichopoda 32 1e-76 286
WERAM-Thc-0058 EOY06689 Theobroma cacao 33 1e-71 270
WERAM-Php-0039 PP1S19_18V6.1 Physcomitrella patens 30 6e-70 264
WERAM-Osl-0029 ABO94205 Ostreococcus lucimarinus 28 1e-52 206
WERAM-Scs-0020 EDO03054 Sclerotinia sclerotiorum 32 4e-34 145
WERAM-Chg-0036 EAQ86947 Chaetomium globosum 31 5e-32 138
WERAM-Ast-0012 CADATEAP00004711 Aspergillus terreus 30 1e-31 137
WERAM-Trv-0038 EHK19817 Trichoderma virens 29 1e-30 134
WERAM-Lab-0060 EDR06536 Laccaria bicolor 31 2e-30 133
WERAM-Asn-0014 CADANIAP00002953 Aspergillus nidulans 29 1e-28 127
WERAM-Pytr-0040 EDU46056 Pyrenophora triticirepentis 28 8e-28 124
WERAM-Asfu-0043 CADAFUAP00009687 Aspergillus fumigatus 27 8e-27 121
WERAM-Trr-0031 EGR47919 Trichoderma reesei 26 4e-24 112
WERAM-Zyt-0022 Mycgr3P46654 Zymoseptoria tritici 27 2e-23 109
Created Date 25-Jun-2016