WERAM Information

Tag Content
WERAM ID WERAM-Hos-0052
Ensembl Protein ID ENSP00000262519.8
Uniprot Accession O15047; SET1A_HUMAN; A6NP62; Q6PIF3; Q8TAJ6
Genbank Protein ID NP_055527.1; XP_005255780.1; XP_006721169.1; XP_011544296.1; XP_011544297.1; XP_011544298.1
Protein Name Histone-lysine N-methyltransferase SETD1A
Genbank Nucleotide ID NM_014712.2; XM_005255723.1; XM_006721106.2; XM_011545994.1; XM_011545995.1; XM_011545996.1
Gene Name SETD1A;Set1;KMT2F;Set1A
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000099381.16 ENST00000262519.12 ENSP00000262519.8
Details
Type Family Domain Substrates AA References (PMIDs)
HMT SET1 SET H3K4 K 20889125; 26886794; 25537518
Status Reviewed
Classification
Type Family E-value Score Start End
HMT SET1 3.20e-46 158.6 1568 1685
Organism Homo sapiens
NCBI Taxa ID 9606
Functional Description
(View)		 Histone methyltransferase that specifically methylates 'Lys-4' of histone H3, when part of the SET1 histone methyltransferase (HMT) complex, but not if the neighboring 'Lys-9' residue is already methylated. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. The non-overalpping localization with SETD1B suggests that SETD1A and SETD1B make non-redundant contributions to the epigenetic control of chromatin structure and gene expression.
Domain Profile
  HMT SET1
           SET1.txt    1 kelevakskikglglvakkeiekeelviEYvGevirsevadkrekeyekkeig.vylfrldedaevvvdatkkgniarfinhscepNcea 89  
                         k+l++ +s+i+++gl+a+++i+++e+viEYvG+ ir++vad+rek+y +++ig +ylfr+d+d  +++datk+gn arfinh+c+pNc+a
  ENSP00000262519.8 1568 KKLRFGRSRIHEWGLFAMEPIAADEMVIEYVGQNIRQMVADMREKRYVQEGIGsSYLFRVDHD--TIIDATKCGNLARFINHCCTPNCYA 1655
                         68999************************************************9*********..************************* PP
           SET1.txt   90 kvvavdgekkiviyakraIekgeeltydYk 119 
                         kv++++++kkiviy+k+ I  +ee+tydYk
  ENSP00000262519.8 1656 KVITIESQKKIVIYSKQPIGVDEEITYDYK 1685
                         *****************************7 PP
Protein Sequence
(Fasta)		MDQEGGGDGQ KAPSFQWRNY KLIVDPALDP ALRRPSQKVY RYDGVHFSVN DSKYIPVEDL 60
QDPRCHVRSK NRDFSLPVPK FKLDEFYIGQ IPLKEVTFAR LNDNVRETFL KDMCRKYGEV 120
EEVEILLHPR TRKHLGLARV LFTSTRGAKE TVKNLHLTSV MGNIIHAQLD IKGQQRMKYY 180
ELIVNGSYTP QTVPTGGKAL SEKFQGSGAA TETAESRRRS SSDTAAYPAG TTAVGTPGNG 240
TPCSQDTSFS SSRQDTPSSF GQFTPQSSQG TPYTSRGSTP YSQDSAYSSS TTSTSFKPRR 300
SENSYQDAFS RRHFSASSAS TTASTAIAAT TAATASSSAS SSSLSSSSSS SSSSSSSQFR 360
SSDANYPAYY ESWNRYQRHT SYPPRRATRE EPPGAPFAEN TAERFPPSYT SYLPPEPSRP 420
TDQDYRPPAS EAPPPEPPEP GGGGGGGGPS PEREEVRTSP RPASPARSGS PAPETTNESV 480
PFAQHSSLDS RIEMLLKEQR SKFSFLASDT EEEEENSSMV LGARDTGSEV PSGSGHGPCT 540
PPPAPANFED VAPTGSGEPG ATRESPKANG QNQASPCSSG DDMEISDDDR GGSPPPAPTP 600
PQQPPPPPPP PPPPPPYLAS LPLGYPPHQP AYLLPPRPDG PPPPEYPPPP PPPPHIYDFV 660
NSLELMDRLG AQWGGMPMSF QMQTQMLTRL HQLRQGKGLI AASAGPPGGA FGEAFLPFPP 720
PQEAAYGLPY ALYAQGQEGR GAYSREAYHL PMPMAAEPLP SSSVSGEEAR LPPREEAELA 780
EGKTLPTAGT VGRVLAMLVQ EMKSIMQRDL NRKMVENVAF GAFDQWWESK EEKAKPFQNA 840
AKQQAKEEDK EKTKLKEPGL LSLVDWAKSG GTTGIEAFAF GSGLRGALRL PSFKVKRKEP 900
SEISEASEEK RPRPSTPAEE DEDDPEQEKE AGEPGRPGTK PPKRDEERGK TQGKHRKSFA 960
LDSEGEEASQ ESSSEKDEED DEEDEEDEDR EEAVDTTKKE TEVSDGEDEE SDSSSKCSLY 1020
ADSDGENDST SDSESSSSSS SSSSSSSSSS SSSSSSSSES SSEDEEEEER PAALPSASPP 1080
PREVPVPTPA PVEVPVPERV AGSPVTPLPE QEASPARPAG PTEESPPSAP LRPPEPPAGP 1140
PAPAPRPDER PSSPIPLLPP PKKRRKTVSF SAIEVVPAPE PPPATPPQAK FPGPASRKAP 1200
RGVERTIRNL PLDHASLVKS WPEEVSRGGR SRAGGRGRLT EEEEAEPGTE VDLAVLADLA 1260
LTPARRGLPA LPAVEDSEAT ETSDEAERPR PLLSHILLEH NYALAVKPTP PAPALRPPEP 1320
VPAPAALFSS PADEVLEAPE VVVAEAEEPK PQQLQQQREE GEEEGEEEGE EEEEESSDSS 1380
SSSDGEGALR RRSLRSHARR RRPPPPPPPP PPRAYEPRSE FEQMTILYDI WNSGLDSEDM 1440
SYLRLTYERL LQQTSGADWL NDTHWVHHTI TNLTTPKRKR RPQDGPREHQ TGSARSEGYY 1500
PISKKEKDKY LDVCPVSARQ LEGVDTQGTN RVLSERRSEQ RRLLSAIGTS AIMDSDLLKL 1560
NQLKFRKKKL RFGRSRIHEW GLFAMEPIAA DEMVIEYVGQ NIRQMVADMR EKRYVQEGIG 1620
SSYLFRVDHD TIIDATKCGN LARFINHCCT PNCYAKVITI ESQKKIVIYS KQPIGVDEEI 1680
TYDYKFPLED NKIPCLCGTE SCRGSLN 1707
Nucleotide Sequence
(Fasta)		ATCCTCAGAA TTCCTCGGGT CCCTCGATAC TCGGCTGAAA ATTCTCATCG GACTCTGAGA 60
GGAGCGCTGG GCTGGAGGCA TTTTCCCCAG GGACAGAAGC GGGCTATTCT CTCACTTGGG 120
CCAGTAAGAA AAATCCAAAA AAAGTTGTCG ACTCTGCCAG CAGGGATTGG CTAACGGGCC 180
GTTATTTTCT TGACTCCACC AAGGCGGATG AAGGGGAGGC TACGGCTGAG GCCGGGAACA 240
GTGGCGAATC TGCAGCCTCT CAGAATTTGG CAGTGCAAGG AAGGGACGGG GAAGAGAAGC 300
AAAGCGGCGC GCATCCTGTC CAGCGATTCG CCCCGCCCGC CCGGTGAATC TGCGTCTGCA 360
GAACGCGCCA CTGAAGGTTC CCCAGCGCTG GCTGGCCTCC TCCCCTCCGC CCCGCCCCTT 420
TTCCTCAGGG ACTAGTCGCA GCTTTCGTCG CCGCCGATTC GTCAAGGTCC CGGGCCGCAG 480
CATCTAGATC GTCGTGGCGA AGCCGACTCT CCGGGGGATG CGGCCAATCT CCAAGCTCCC 540
TGGGCCGCAA CTTCCGAGCC TCCCAGGGCG CCGGCCGAGG CGAAGCCGCT ACCCTCGGCC 600
CCGTGGGTCC CCCGGCAGCG CCTGTGGCGA AAGTGCGAAT GCAGACCCTG TGCCCGCTGG 660
GCCTCGCGCA GTGTAAATGA GCAAAGATGG ATCAGGAAGG TGGGGGAGAT GGGCAGAAGG 720
CCCCGAGCTT CCAGTGGCGG AACTACAAGC TCATCGTGGA TCCTGCCTTG GACCCTGCCC 780
TGCGCAGGCC TTCTCAGAAG GTGTACCGCT ATGATGGAGT CCACTTCAGT GTCAACGACT 840
CAAAGTATAT ACCAGTCGAA GACCTCCAAG ACCCCCGTTG CCATGTCAGG TCCAAAAACA 900
GAGACTTTTC CCTCCCAGTC CCTAAGTTTA AGCTGGACGA GTTCTATATT GGACAGATTC 960
CACTGAAGGA AGTGACTTTT GCAAGGCTGA ATGACAACGT GCGGGAGACC TTCCTGAAGG 1020
ATATGTGCCG TAAGTACGGT GAGGTGGAAG AGGTAGAGAT CCTCCTTCAC CCCCGTACGC 1080
GCAAGCACCT GGGCCTGGCC CGTGTGCTCT TCACCAGCAC TCGGGGCGCC AAGGAAACGG 1140
TCAAAAACCT CCACCTTACC TCCGTCATGG GCAACATCAT CCATGCCCAG CTTGACATCA 1200
AAGGACAACA ACGAATGAAA TACTATGAAC TAATTGTCAA TGGCTCCTAC ACCCCTCAGA 1260
CTGTGCCCAC TGGGGGCAAG GCCCTGAGTG AGAAGTTCCA AGGCTCGGGT GCAGCCACTG 1320
AGACGGCCGA ATCCCGCCGC CGCTCTTCCT CTGACACAGC TGCCTACCCA GCAGGCACCA 1380
CTGCGGTGGG CACTCCTGGC AACGGCACCC CCTGCTCCCA GGACACAAGC TTCTCCAGCA 1440
GCCGACAAGA TACCCCATCT TCCTTTGGCC AGTTCACACC TCAGTCCTCC CAAGGAACCC 1500
CCTACACGTC TCGGGGCAGC ACCCCCTACT CTCAGGACTC TGCCTACTCC AGCAGCACCA 1560
CTTCAACCTC CTTCAAGCCC CGGCGGTCAG AGAACAGCTA CCAAGATGCC TTTTCCCGCC 1620
GCCACTTCTC TGCATCTTCA GCCTCCACAA CCGCCTCCAC GGCCATCGCC GCCACCACTG 1680
CAGCCACTGC CTCATCCTCC GCCTCTTCCT CCTCATTGTC CTCGTCCTCC TCGTCATCCT 1740
CTTCCTCCTC GTCCTCTCAG TTTCGTAGTT CTGATGCAAA CTACCCAGCG TATTATGAAA 1800
GCTGGAATCG CTACCAGCGC CATACTTCCT ACCCACCACG CCGGGCCACA CGGGAGGAAC 1860
CCCCTGGAGC CCCTTTTGCT GAAAATACAG CTGAGCGCTT CCCACCTTCT TACACCTCCT 1920
ACCTGCCCCC CGAGCCCAGC CGGCCCACCG ACCAGGACTA CCGGCCTCCT GCCTCAGAGG 1980
CTCCACCCCC GGAGCCTCCA GAACCTGGTG GAGGCGGGGG TGGAGGAGGG CCCAGCCCTG 2040
AGAGAGAAGA AGTTCGGACT TCCCCCCGCC CAGCCTCCCC TGCCCGCTCT GGCTCCCCAG 2100
CCCCGGAGAC CACCAATGAG AGTGTGCCCT TCGCCCAGCA CAGCAGCCTG GATTCCCGCA 2160
TCGAGATGCT GCTGAAGGAG CAGCGCTCCA AGTTTTCCTT CTTGGCCTCT GACACAGAGG 2220
AGGAGGAAGA GAACAGCAGC ATGGTCCTTG GGGCCAGAGA TACAGGGAGT GAGGTGCCTT 2280
CTGGGTCAGG GCATGGGCCC TGCACACCCC CTCCGGCCCC AGCTAATTTT GAGGATGTGG 2340
CACCTACAGG GAGCGGGGAG CCAGGGGCTA CCCGGGAGTC TCCCAAGGCA AATGGACAGA 2400
ACCAGGCTTC TCCATGCTCT TCTGGAGACG ACATGGAGAT CTCCGACGAC GACCGGGGTG 2460
GCTCACCCCC TCCGGCCCCG ACGCCCCCTC AGCAGCCTCC GCCACCTCCC CCTCCCCCGC 2520
CGCCTCCTCC TCCCTACCTG GCGTCCCTTC CTCTTGGTTA TCCTCCCCAC CAACCTGCCT 2580
ACCTCCTCCC ACCCAGACCT GATGGGCCGC CGCCCCCTGA GTACCCCCCA CCTCCTCCAC 2640
CACCCCCGCA CATCTATGAC TTTGTGAACT CCTTGGAGCT CATGGACCGA CTTGGGGCTC 2700
AGTGGGGAGG GATGCCCATG TCCTTCCAGA TGCAGACCCA GATGTTAACT CGGCTCCATC 2760
AGCTGCGGCA GGGCAAGGGA TTGATTGCCG CCTCAGCTGG CCCCCCCGGT GGGGCCTTTG 2820
GGGAGGCCTT CCTCCCGTTT CCACCCCCGC AGGAGGCAGC CTACGGCTTG CCGTATGCTC 2880
TATATGCACA GGGGCAGGAG GGCAGAGGGG CATACTCACG GGAGGCCTAC CACCTGCCCA 2940
TGCCAATGGC AGCCGAGCCC CTGCCCTCCT CCTCAGTCTC GGGAGAGGAG GCCCGGCTGC 3000
CACCCAGGGA AGAAGCAGAG CTGGCAGAGG GCAAGACCCT CCCGACAGCA GGCACCGTGG 3060
GCCGTGTGCT CGCCATGCTG GTCCAGGAGA TGAAGAGCAT CATGCAGCGA GACCTCAACC 3120
GCAAGATGGT GGAGAACGTG GCCTTCGGAG CCTTTGACCA GTGGTGGGAG AGCAAGGAGG 3180
AGAAGGCCAA GCCATTCCAG AACGCGGCCA AGCAGCAAGC CAAGGAGGAG GATAAAGAGA 3240
AGACGAAGCT GAAGGAGCCT GGCCTGCTGT CCCTCGTGGA CTGGGCCAAG AGCGGGGGCA 3300
CTACGGGCAT CGAGGCTTTC GCCTTTGGGT CAGGGCTGAG AGGGGCCCTG CGGCTGCCTT 3360
CATTCAAGGT AAAGCGGAAA GAGCCATCGG AAATTTCCGA GGCCAGTGAG GAAAAGAGGC 3420
CTCGTCCCTC CACTCCTGCT GAGGAAGATG AAGACGACCC TGAACAAGAG AAGGAGGCTG 3480
GAGAGCCAGG ACGTCCGGGG ACCAAGCCCC CGAAGCGGGA CGAAGAGCGA GGCAAGACCC 3540
AGGGCAAGCA CCGCAAGTCC TTTGCTCTGG ACAGCGAAGG GGAGGAGGCA TCCCAGGAGT 3600
CCTCCTCGGA GAAGGATGAG GAGGATGACG AGGAAGATGA GGAAGATGAA GATCGAGAGG 3660
AAGCTGTGGA TACCACAAAG AAGGAGACAG AGGTGTCGGA TGGCGAGGAC GAGGAAAGCG 3720
ATTCGTCTTC CAAATGTTCT CTGTATGCTG ACTCAGATGG CGAAAATGAC AGCACATCAG 3780
ACTCCGAGAG CAGCAGCTCT TCCAGCTCCT CATCCTCCTC CTCCTCCTCG TCCTCATCCT 3840
CCTCGTCCTC TTCATCCTCT GAGTCCTCCT CTGAAGATGA AGAGGAAGAG GAGCGGCCAG 3900
CAGCCCTTCC CTCAGCCTCC CCGCCCCCCA GAGAAGTCCC AGTGCCCACG CCAGCACCTG 3960
TGGAGGTGCC AGTGCCGGAA AGGGTTGCAG GCTCCCCAGT CACACCCCTG CCCGAACAGG 4020
AGGCGTCTCC AGCAAGGCCT GCAGGCCCCA CGGAGGAGTC ACCCCCCAGT GCGCCTCTGC 4080
GTCCCCCAGA ACCACCTGCT GGGCCCCCGG CCCCTGCCCC ACGCCCCGAT GAGCGTCCCT 4140
CTTCTCCCAT CCCCCTCCTG CCCCCACCCA AGAAACGCCG GAAAACTGTC TCCTTCTCTG 4200
CCATCGAGGT GGTGCCAGCC CCGGAGCCCC CTCCAGCCAC ACCGCCGCAG GCCAAGTTTC 4260
CCGGCCCAGC CTCCCGCAAG GCTCCCCGGG GCGTGGAGCG GACCATCCGC AACCTGCCCC 4320
TGGACCACGC ATCTCTGGTC AAGAGTTGGC CCGAGGAGGT GTCCCGAGGA GGCCGGAGCC 4380
GGGCTGGAGG CCGAGGCCGC CTCACCGAGG AAGAGGAGGC TGAGCCAGGG ACAGAGGTGG 4440
ACCTGGCGGT CCTGGCCGAC CTGGCCCTGA CCCCTGCCCG GCGCGGGCTG CCTGCCCTGC 4500
CTGCTGTTGA AGACTCAGAG GCCACAGAGA CATCGGACGA GGCCGAGCGC CCTAGGCCCC 4560
TGCTCAGCCA CATCCTCCTG GAGCACAACT ATGCCCTGGC CGTCAAGCCC ACGCCCCCTG 4620
CGCCAGCCCT GCGGCCCCCG GAGCCAGTGC CCGCACCCGC CGCCCTCTTC AGTTCCCCAG 4680
CTGATGAGGT CCTGGAGGCC CCCGAGGTGG TGGTGGCTGA GGCGGAGGAG CCCAAGCCGC 4740
AGCAACTGCA GCAGCAGCGG GAGGAGGGCG AAGAGGAGGG GGAGGAAGAG GGGGAGGAAG 4800
AGGAGGAGGA GTCCTCTGAC AGCAGCAGCA GCAGCGATGG GGAGGGCGCC CTCCGGAGGC 4860
GCAGCCTCCG CTCCCACGCC CGGCGCCGCC GCCCTCCGCC CCCACCCCCG CCGCCACCGC 4920
CCCGCGCCTA CGAGCCACGC AGTGAGTTTG AACAGATGAC CATCCTGTAT GACATTTGGA 4980
ACTCGGGCCT GGACTCAGAG GACATGAGTT ACCTGCGGCT TACGTACGAG CGGCTGCTGC 5040
AGCAGACAAG CGGGGCTGAC TGGCTCAACG ACACTCACTG GGTCCATCAC ACAATCACCA 5100
ACCTGACCAC CCCAAAACGC AAGCGGCGGC CCCAGGATGG GCCCCGGGAG CACCAGACAG 5160
GCTCAGCCCG CAGCGAAGGC TACTACCCCA TCAGCAAGAA GGAGAAGGAC AAGTACCTGG 5220
ACGTGTGCCC AGTCTCGGCC CGGCAGCTGG AGGGCGTGGA CACTCAGGGG ACGAACCGCG 5280
TGCTGTCCGA GCGCCGGTCC GAGCAGCGGC GGCTGCTGAG CGCCATCGGT ACCTCCGCCA 5340
TCATGGACAG TGACCTGCTG AAACTCAACC AGCTCAAGTT CCGGAAGAAG AAGCTCCGAT 5400
TTGGCCGGAG CCGGATCCAC GAGTGGGGTC TGTTTGCCAT GGAACCCATT GCTGCTGACG 5460
AGATGGTCAT CGAATACGTG GGTCAGAACA TCCGTCAGAT GGTGGCCGAC ATGCGGGAGA 5520
AGCGCTACGT GCAGGAGGGC ATTGGCAGCA GCTACCTGTT CCGGGTGGAC CACGACACCA 5580
TCATCGATGC CACCAAGTGT GGCAACCTGG CCAGATTCAT CAACCACTGC TGCACGCCTA 5640
ACTGCTACGC CAAGGTCATC ACCATCGAGT CCCAGAAGAA GATCGTGATC TACTCCAAGC 5700
AGCCCATTGG CGTGGACGAG GAGATCACCT ACGACTACAA GTTCCCACTG GAAGACAACA 5760
AGATCCCGTG TCTGTGTGGC ACAGAGAGCT GCCGGGGCTC CCTAAACTGA GGTGGGGCAG 5820
GATGGGTGCC CACACCCCTA TTTATTCCCC CTGGTGCCCT GAGCTCCCAG CACCCCCCCA 5880
GCCTTAGTGG GCTCAGCAGG GCCCACATGC CCCCATCTCC AAGCGTGGGG TTGGGGGCCC 5940
CAAGCCCAGC GAGGGAGCCT CAGTCCCTGG AGGCAGCTTC TGCCTCTCCT GTCACCCCTG 6000
CCCACCACCC CCTGATTGTT TTTCTTTGCG GAGAAGAAGC TGTAAATGTT TTGTAGCAGC 6060
CAGCAGCTGT TTCCTGTGGA AACCTGGGGT GCCGGCCTGT ACAGATTCTG TCCTGGGGGG 6120
CTACACAGTC CTCTTGCTTT GTGTTAATGG GGACTTCCCC TTACGCCCTG CGTGTACCCC 6180
TCCCCAGTTT AGGGGTCTCT GGGGCAGTGG CCATGTTCTC CCCCTGGGGG GGCTCTGCAC 6240
CCCCAGTCCT GGGGACTCCG TGCCTGGAAC CCTGCCTCAT CTGTTCCTGC CAGACCCTGA 6300
GGGTCACCCT TCCACCCTGG TGTCACTCCC CGGCTCAGCC AGGCCAGGAT GGCGGGGTGG 6360
GTCCCTTTTG CTGGGCTGGA CTGTACATAT GTTAATAGCG CAAACCCGAC GCCACATTTT 6420
TATAATTGTG ATTAAACTTT ATTGTACAAA AGTGTTTGGT CGGTGTATTT GGGCAGGAGC 6480
GAGGGGTTGG GGGTAGAGGG CACGGAGGGT TGTGCAAGTT GAAGAGAGGG AAAAGTGGGT 6540
ACCTGAAGTG TGGGGCAGGT AAAGGGGCCT TCAGGCAAGA GCCCAGACCT GCAGAGACAG 6600
TCCGAGACTG TCTCGGACCC CCTGACAGGC TGCAGCAGCC GCACCCGCAC CAGGAATACC 6660
CCACCAGTGC CCGCCAGGGT GGTGCCAAGG TCAGGCCTCC CCTTCCTACA ATCACAGCTG 6720
CAGCTGGACC TCCGGCCTCC TGGGAAGCCC AGCAGGAGGG AAGGCCTGAG GTCACACTGT 6780
GGGATGAGGT CACCGCTGGC TCCACCCACA GCCCCAGACC CCTTCAGCCC ACTCTGCAAG 6840
TTCGAGCTTC ATCCCCACCA AGTTCTCCGC TGGACCCAGA TGCCAGTGGA GCACAGAGCG 6900
GCC 6904
Sequence Source Ensembl
Keyword

KW-0002--3D-structure
KW-0010--Activator
KW-0156--Chromatin regulator
KW-0158--Chromosome
KW-0181--Complete proteome
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0694--RNA-binding
KW-0949--S-adenosyl-L-methionine
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0808--Transferase
--
Interpro

IPR024657--COMPASS_Set1_N-SET
IPR012677--Nucleotide-bd_a/b_plait
IPR003616--Post-SET_dom
IPR000504--RRM_dom
IPR001214--SET_dom
PROSITE

PS50868--POST_SET
PS50102--RRM
PS50280--SET
Pfam

PF11764--N-SET
PF00076--RRM_1
PF00856--SET
Gene Ontology

GO:0005694--C:chromosome
GO:0035097--C:histone methyltransferase complex
GO:0016607--C:nuclear speck
GO:0005654--C:nucleoplasm
GO:0005634--C:nucleus
GO:0048188--C:Set1C/COMPASS complex
GO:0008013--F:beta-catenin binding
GO:0042800--F:histone methyltransferase activity (H3-K4 specific)
GO:0018024--F:histone-lysine N-methyltransferase activity
GO:0000166--F:nucleotide binding
GO:0003723--F:RNA binding
GO:0051568--P:histone H3-K4 methylation
GO:0034968--P:histone lysine methylation
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated
Orthology
WERAM ID Ensembl Protein ID Species Identity E-value Score
WERAM-Pat-0062 ENSPTRP00000013706.5 Pan troglodytes 100 0.0 1406
WERAM-Poa-0065 ENSPPYP00000008244.1 Pongo abelii 99 0.0 1390
WERAM-Chs-0064 ENSCSAP00000002085.1 Chlorocebus sabaeus 99 0.0 1389
WERAM-Paa-0204 ENSPANP00000012566.1 Papio anubis 97 0.0 1382
WERAM-Gog-0177 ENSGGOP00000015665.2 Gorilla gorilla 94 0.0 1382
WERAM-Ict-0055 ENSSTOP00000004843.2 Ictidomys tridecemlineatus 97 0.0 1350
WERAM-Cap-0213 ENSCPOP00000014263.1 Cavia porcellus 95 0.0 1347
WERAM-Loa-0185 ENSLAFP00000017456.2 Loxodonta africana 96 0.0 1345
WERAM-Caj-0027 ENSCJAP00000005463.1 Callithrix jacchus 89 0.0 1342
WERAM-Fec-0032 ENSFCAP00000002386.3 Felis catus 95 0.0 1331
WERAM-Tut-0173 ENSTTRP00000014681.1 Tursiops truncatus 94 0.0 1321
WERAM-Bot-0028 ENSBTAP00000003027.5 Bos taurus 95 0.0 1319
WERAM-Caf-0173 ENSCAFP00000024640.4 Canis familiaris 94 0.0 1315
WERAM-Ocp-0140 ENSOPRP00000014662.2 Ochotona princeps 87 0.0 1256
WERAM-Ova-0084 ENSOARP00000008806.1 Ovis aries 86 0.0 1221
WERAM-Mup-0132 ENSMPUP00000011776.1 Mustela putorius furo 90 0.0 1207
WERAM-Nol-0173 ENSNLEP00000019485.2 Nomascus leucogenys 99 0.0 1207
WERAM-Myl-0210 ENSMLUP00000019261.1 Myotis lucifugus 85 0.0 1202
WERAM-Tub-0068 ENSTBEP00000008424.1 Tupaia belangeri 87 0.0 1147
WERAM-Sah-0118 ENSSHAP00000012602.1 Sarcophilus harrisii 77 0.0 1100
WERAM-Mae-0036 ENSMEUP00000003113.1 Macropus eugenii 77 0.0 1080
WERAM-Mod-0019 ENSMODP00000002114.4 Monodelphis domestica 76 0.0 1075
WERAM-Dio-0099 ENSDORP00000009999.1 Dipodomys ordii 94 0.0 976
WERAM-Mim-0015 ENSMICP00000001436.1 Microcebus murinus 95 0.0 938
WERAM-Otg-0198 ENSOGAP00000018783.1 Otolemur garnettii 67 0.0 931
WERAM-Sus-0054 ENSSSCP00000008310.2 Sus scrofa 95 0.0 888
WERAM-Aim-0086 ENSAMEP00000007965.1 Ailuropoda melanoleuca 86 0.0 811
WERAM-Ptv-0119 ENSPVAP00000010415.1 Pteropus vampyrus 94 0.0 810
WERAM-Ran-0237 ENSRNOP00000073937.1 Rattus norvegicus 92 0.0 674
WERAM-Mum-0173 ENSMUSP00000037600.6 Mus musculus 93 0.0 672
WERAM-Orc-0179 ENSOCUP00000024772.2 Oryctolagus cuniculus 94 3e-157 554
WERAM-Mam-0025 ENSMMUP00000004313.2 Macaca mulatta 100 1e-151 535
WERAM-Eqc-0117 ENSECAP00000012842.1 Equus caballus 96 3e-147 521
WERAM-Pes-0031 ENSPSIP00000005432.1 Pelodiscus sinensis 88 5e-135 480
WERAM-Anc-0078 ENSACAP00000007457.3 Anolis carolinensis 83 6e-131 467
WERAM-Ere-0113 ENSEEUP00000012035.1 Erinaceus europaeus 85 4e-129 461
WERAM-Dar-0130 ENSDARP00000108328.2 Danio rerio 83 5e-125 447
WERAM-Tas-0122 ENSTSYP00000013245.1 Tarsius syrichta 100 4e-124 444
WERAM-Pof-0164 ENSPFOP00000013714.1 Poecilia formosa 82 4e-124 444
WERAM-Xet-0013 ENSXETP00000004082.3 Xenopus tropicalis 80 9e-123 439
WERAM-Ten-0182 ENSTNIP00000017976.1 Tetraodon nigroviridis 81 5e-122 437
WERAM-Lac-0029 ENSLACP00000004520.1 Latimeria chalumnae 74 2e-121 435
WERAM-Xim-0086 ENSXMAP00000008046.1 Xiphophorus maculatus 80 7e-121 433
WERAM-Tar-0109 ENSTRUP00000022509.1 Takifugu rubripes 81 1e-118 426
WERAM-Orn-0122 ENSONIP00000012381.1 Oreochromis niloticus 79 2e-118 425
WERAM-Gaa-0140 ENSGACP00000018090.2 Gasterosteus aculeatus 75 3e-116 418
WERAM-Gam-0148 ENSGMOP00000014765.1 Gadus morhua 78 3e-115 415
WERAM-Meg-0046 ENSMGAP00000004251.2 Meleagris gallopavo 67 2e-103 375
WERAM-Anp-0044 ENSAPLP00000004792.1 Anas platyrhynchos 67 2e-103 375
WERAM-Gaga-0050 ENSGALP00000038427.1 Gallus gallus 67 2e-103 375
WERAM-Fia-0111 ENSFALP00000009530.1 Ficedula albicollis 67 3e-103 375
WERAM-Tag-0093 ENSTGUP00000006270.1 Taeniopygia guttata 67 3e-103 375
WERAM-Leo-0043 ENSLOCP00000006248.1 Lepisosteus oculatus 66 3e-102 371
WERAM-Asm-0221 ENSAMXP00000021274.1 Astyanax mexicanus 66 3e-102 371
WERAM-Ora-0110 ENSOANP00000020840.3 Ornithorhynchus anatinus 64 2e-100 365
WERAM-Dan-0139 ENSDNOP00000029039.1 Dasypus novemcinctus 63 2e-99 362
WERAM-Orla-0085 ENSORLP00000010594.1 Oryzias latipes 67 4e-98 358
WERAM-Pem-0093 ENSPMAP00000009706.1 Petromyzon marinus 63 1e-90 333
WERAM-Drm-0077 FBpp0291453 Drosophila melanogaster 50 6e-79 294
WERAM-Cis-0056 ENSCSAVP00000012508.1 Ciona savignyi 50 1e-70 266
WERAM-Cii-0028 ENSCINP00000011316.3 Ciona intestinalis 50 3e-69 261
WERAM-Scj-0004 EEB05744 Schizosaccharomyces japonicus 47 1e-54 213
WERAM-Yal-0004 CAG83155 Yarrowia lipolytica 44 3e-54 212
WERAM-Cae-0021 C26E6.9a Caenorhabditis elegans 68 3e-53 209
WERAM-Scp-0045 SPCC306.04c.1:pep Schizosaccharomyces pombe 54 8e-53 207
WERAM-Miv-0032 MVLG_04704T0 Microbotryum violaceum 46 5e-52 204
WERAM-Asni-0037 CADANGAP00014055 Aspergillus niger 42 5e-52 204
WERAM-Pug-0037 EHS63201 Puccinia graminis 67 5e-52 204
WERAM-Kll-0032 CAG98863 Kluyveromyces lactis 63 2e-51 203
WERAM-Kop-0022 CAY69541 Komagataella pastoris 50 3e-51 202
WERAM-Mel-0029 EGG07883 Melampsora laricipopulina 67 4e-51 202
WERAM-Pytr-0027 EDU41796 Pyrenophora triticirepentis 40 6e-51 201
WERAM-Org-0116 ORGLA12G0159200.1 Oryza glaberrima 66 7e-51 201
WERAM-Ors-0112 OS12T0613200-02 Oryza sativa 66 8e-51 201
WERAM-Mua-0156 GSMUA_AchrUn_randomP11970_001 Musa acuminata 65 8e-51 201
WERAM-Php-0006 PP1S101_4V6.1 Physcomitrella patens 66 9e-51 200
WERAM-Pyt-0002 EFQ96340 Pyrenophora teres 40 1e-50 200
WERAM-Caa-0001 KGT72293 Candida albicans 51 1e-50 200
WERAM-Orbr-0127 OB12G25360.1 Oryza brachyantha 65 2e-50 199
WERAM-Phn-0012 SNOT_03803 Phaeosphaeria nodorum 40 3e-50 199
WERAM-Lem-0021 CBX90234 Leptosphaeria maculans 40 4e-50 198
WERAM-Usm-0019 UM02677P0 Ustilago maydis 43 4e-50 198
WERAM-Coi-0035 EAS31778 Coccidioides immitis 41 6e-50 197
WERAM-Fuo-0006 FOXG_01447P0 Fusarium oxysporum 61 7e-50 197
WERAM-Scs-0015 EDO00210 Sclerotinia sclerotiorum 62 7e-50 197
WERAM-Spr-0026 CBQ73061 Sporisorium reilianum 43 9e-50 197
WERAM-Pot-0072 POPTR_0005s28130.1 Populus trichocarpa 64 1e-49 197
WERAM-Asfu-0007 CADAFUAP00002016 Aspergillus fumigatus 62 1e-49 196
WERAM-Sol-0003 Solyc01g006880.2.1 Solanum lycopersicum 63 2e-49 196
WERAM-Sei-0078 Si021071m Setaria italica 63 2e-49 196
WERAM-Tum-0027 CAZ85029 Tuber melanosporum 62 2e-49 196
WERAM-Ast-0003 CADATEAP00001100 Aspergillus terreus 41 2e-49 196
WERAM-Asn-0015 CADANIAP00003254 Aspergillus nidulans 62 2e-49 196
WERAM-Prp-0018 EMJ21490 Prunus persica 63 3e-49 196
WERAM-Glm-0101 GLYMA09G05735.1 Glycine max 62 3e-49 195
WERAM-Brd-0092 BRADI4G01790.1 Brachypodium distachyon 65 4e-49 195
WERAM-Thc-0094 EOY15831 Theobroma cacao 63 5e-49 194
WERAM-Cag-0030 CAG62307 Candida glabrata 61 5e-49 194
WERAM-Asg-0003 AAS50907 Ashbya gossypii 62 6e-49 194
WERAM-Trv-0023 EHK27489 Trichoderma virens 59 7e-49 194
WERAM-Trr-0040 EGR44940 Trichoderma reesei 59 7e-49 194
WERAM-Sac-0021 YHR119W Saccharomyces cerevisiae 61 8e-49 194
WERAM-Aso-0006 CADAORAP00000676 Aspergillus oryzae 61 8e-49 194
WERAM-Asc-0034 CADACLAP00008186 Aspergillus clavatus 61 9e-49 194
WERAM-Lab-0005 EDR10511 Laccaria bicolor 64 1e-48 193
WERAM-Chg-0032 EAQ86448 Chaetomium globosum 59 4e-48 192
WERAM-Nec-0021 EFNCRP00000004417 Neurospora crassa 59 4e-48 191
WERAM-Amt-0029 ERN11464 Amborella trichopoda 65 7e-48 191
WERAM-Gag-0022 GGTG_06874T0 Gaeumannomyces graminis 47 9e-48 190
WERAM-Brr-0140 Bra027983.1-P Brassica rapa 60 1e-47 190
WERAM-Bro-0175 Bo9g058280.1 Brassica oleracea 60 1e-47 190
WERAM-Orgl-0122 OGLUM12G20310.1 Oryza glumaepatula 66 2e-47 189
WERAM-Ori-0122 BGIOSGA035842-PA Oryza indica 65 3e-47 189
WERAM-Mao-0038 MGG_15053T0 Magnaporthe oryzae 60 4e-47 188
WERAM-Map-0034 MAPG_11216T0 Magnaporthe poae 42 5e-47 188
WERAM-Tra-0213 Traes_5BS_427C77CAB.2 Triticum aestivum 65 8e-47 187
WERAM-Tru-0014 TRIUR3_06753-P1 Triticum urartu 64 4e-46 185
WERAM-Aet-0024 EMT10715 Aegilops tauschii 64 1e-45 183
WERAM-Sob-0112 Sb08g002530.1 Sorghum bicolor 65 1e-45 183
WERAM-Zem-0147 GRMZM2G473138_P01 Zea mays 64 1e-45 183
WERAM-Ved-0007 EGY17741 Verticillium dahliae 56 3e-45 182
WERAM-Sem-0101 EFJ35870 Selaginella moellendorffii 58 4e-45 182
WERAM-Crn-0015 AAW43251 Cryptococcus neoformans 46 9e-45 180
WERAM-Zyt-0002 Mycgr3P10108 Zymoseptoria tritici 56 2e-44 179
WERAM-Arl-0117 fgenesh2_kg.8__ 611__ AT5G42400.1 Arabidopsis lyrata 59 3e-44 179
WERAM-Met-0043 AES65156 Medicago truncatula 61 4e-44 178
WERAM-Art-0135 AT5G42400.1 Arabidopsis thaliana 60 4e-44 178
WERAM-Cym-0010 CMG025CT Cyanidioschyzon merolae 50 9e-39 160
WERAM-Soa-0133 ENSSARP00000013142.1 Sorex araneus 56 1e-38 160
WERAM-Ect-0072 ENSETEP00000007880.1 Echinops telfairi 56 1e-38 160
WERAM-Prc-0053 ENSPCAP00000005189.1 Procavia capensis 56 2e-38 160
Created Date 25-Jun-2016