WERAM Information

Tag Content
WERAM ID WERAM-Mum-0143
Ensembl Protein ID ENSMUSP00000119057.2
Uniprot Accession Q5DW34; EHMT1_MOUSE; A2AIS3; A2AIS4; Q5EBR1; Q6PGM0
Genbank Protein ID NP_001012536.2; NP_001103156.1; NP_001103157.1
Protein Name Histone-lysine N-methyltransferase EHMT1
Genbank Nucleotide ID NM_001012518.3; NM_001109686.2; NM_001109687.2
Gene Name Glp;EHMT1;Euhmtase1;Kmt1d
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000036893.17 ENSMUST00000147147.7 ENSMUSP00000119057.2
ENSMUSG00000036893.17 ENSMUST00000046227.11 ENSMUSP00000046077.5
ENSMUSG00000036893.17 ENSMUST00000091348.10 ENSMUSP00000088906.5
ENSMUSG00000036893.17 ENSMUST00000102938.9 ENSMUSP00000100002.4
ENSMUSG00000036893.17 ENSMUST00000114418.9 ENSMUSP00000110061.3
ENSMUSG00000036893.17 ENSMUST00000114432.8 ENSMUSP00000110075.2
Details
Type Family Domain Substrates AA References (PMIDs)
HMT SUV39 SET H3K9 K 25294562
Me_Reader Ankyrin ANK1-8 H3K9me1/2 K 18818694
Status Reviewed
Classification
Type Family E-value Score Start End
Me_Reader Ankyrin 1.10e-148 494.6 735 965
HMT SUV39 2.00e-40 139.7 1125 1241
Organism Mus musculus
NCBI Taxa ID 10090
Functional Description
(View)		 Histone methyltransferase that specifically mono- and dimethylates 'Lys-9' of histone H3 (H3K9me1 and H3K9me2, respectively) in euchromatin. H3K9me represents a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. Also weakly methylates 'Lys-27' of histone H3 (H3K27me). Also required for DNA methylation, the histone methyltransferase activity is not required for DNA methylation, suggesting that these 2 activities function independently. Probably targeted to histone H3 by different DNA-binding proteins like E2F6, MGA, MAX and/or DP1. During G0 phase, it probably contributes to silencing of MYC- and E2F-responsive genes, suggesting a role in G0/G1 transition in cell cycle. In addition to the histone methyltransferase activity, also methylates non-histone proteins: mediates dimethylation of 'Lys-373' of p53/TP53.
Domain Profile
  Me_Reader Ankyrin
    ANKYRIN_REPEAT.txt   1 fhpkqlylsvkqgelqkvllmlldnldpnfkseqqskrsplhaaaekgsveichvllqaganidavdkdqrtplmeavvnnhlevvkyl 89 
                           fhpkqly+s++qgelqkvllml+d++dpnfk+e+qskrsplhaaae+g+v+ich+l+qaganid++++dqrtplmea++nnhl++vkyl
  ENSMUSP00000119057.2 735 FHPKQLYFSARQGELQKVLLMLVDGIDPNFKMEHQSKRSPLHAAAEAGHVDICHMLVQAGANIDTCSEDQRTPLMEAAENNHLDAVKYL 823
                           9**************************************************************************************** PP
    ANKYRIN_REPEAT.txt  90 vkagalvdskeeegstclhlaakkgnlevvslllstgqvdvnaqddggwtpiiwaaeykhvelvklllskgadvtlrdneeniclhwaa 178
                           +kaga+vd+k++egstclhlaakkg+++vv++lls+gq+dvn+qddggwtp+iwa+eykhvelvklllskg+d+++rdneeniclhwaa
  ENSMUSP00000119057.2 824 IKAGAQVDPKDAEGSTCLHLAAKKGHYDVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVELVKLLLSKGSDINIRDNEENICLHWAA 912
                           ***************************************************************************************** PP
    ANKYRIN_REPEAT.txt 179 fsgsvdiaevllaakcdlhavnihgdsplhiaaresrydcvllflsrdadvel 231
                           fsg+vdiae+llaakcdlhavnihgdsplhiaare+rydcv+lflsrd+dv+l
  ENSMUSP00000119057.2 913 FSGCVDIAEILLAAKCDLHAVNIHGDSPLHIAARENRYDCVVLFLSRDSDVTL 965
                           **************************************************997 PP
  HMT SUV39
             SUV39.txt    2 rLqvfktenkGwGvrclddiakgsFvciyaGeiltddeaekegleegdeyladldske 59  
                            rLq+++t++ GwGvr+l+di+ g+Fvc+y+Ge+++d+ea+ +   e+d+yl+dld+k+
  ENSMUSP00000119057.2 1125 RLQLYRTQDMGWGVRSLQDIPLGTFVCEYVGELISDSEADVR---EEDSYLFDLDNKD 1179
                            8***************************************98...9*********986 PP
             SUV39.txt   87 keeseyiidakkegnvgrflnHscspNlfvqnvfvdthdlrfprvafFaskrikagtELtwdYg 150 
                            k+ ++y+ida+ +gnv+rf+nH+c+pNl+  +vf++++dlrfpr+afF+++ i+ag++L +dYg
  ENSMUSP00000119057.2 1178 KDGEVYCIDARFYGNVSRFINHHCEPNLVPVRVFMSHQDLRFPRIAFFSTRLIQAGEQLGFDYG 1241
                            67899**********************************************************6 PP
Protein Sequence
(Fasta)		MAAADAEQAV LAKQETKQDC CMKTELLRED TPMAADEGST EKQEGETPMA ADGETNGSCE 60
KSGDPSHLNA PKHTQENTRA SPQEGTNRVS RVAENGVSER DTEVGKQNHV TADDFMQTSV 120
IGSNGYFLNK PALQGQPLRT PNILTSSLPG HAAKTLPGGA SKCRTLSALP QTPTTAPTVP 180
GEGSADTEDR KPTASGTDVR VHRARKTMPK SILGLHAASK DHREVQDHKE PKEDINRNIS 240
ECGRQQLLPT FPALHQSLPQ NQCYMATTKS QTACLPFVLA AAVSRKKKRR MGTYSLVPKK 300
KTKVLKQRTV IEMFKSITHS TVGAKGEKAL DDSALHVNGE SLEMDSEDED SDELEDDEDH 360
GAEQAAAFPT EDSRTSKESM SETDRAAKMD GDSEEEQESP DTGEDEDGGD ESDLSSESSI 420
KKKFLKRRGK TDSPWIKPAR KRRRRSRKKP SSMLGSEACK SSPGSMEQAA LGDSAGYMEV 480
SLDSLDLRVR GILSSQTENE GLASGPDVLG TDGLQEVPLC SCRMETPKSR EISTLANNQC 540
MATESVDHEL GRCTNSVVKY ELMRPSNKAP LLVLCEDHRG RMVKHQCCPG CGYFCTAGNF 600
MECQPESSIS HRFHKDCASR VNNASYCPHC GEEASKAKEV TIAKADTTST VTLAPGQEKS 660
LAAEGRADTT TGSIAGAPED ERSQSTAPQA PECFDPAGPA GLVRPTSGLS QGPGKETLES 720
ALIALDSEKP KKLRFHPKQL YFSARQGELQ KVLLMLVDGI DPNFKMEHQS KRSPLHAAAE 780
AGHVDICHML VQAGANIDTC SEDQRTPLME AAENNHLDAV KYLIKAGAQV DPKDAEGSTC 840
LHLAAKKGHY DVVQYLLSNG QMDVNCQDDG GWTPMIWATE YKHVELVKLL LSKGSDINIR 900
DNEENICLHW AAFSGCVDIA EILLAAKCDL HAVNIHGDSP LHIAARENRY DCVVLFLSRD 960
SDVTLKNKEG ETPLQCASLS SQVWSALQMS KALRDSAPDK PVAVEKTVSR DIARGYERIP 1020
IPCVNAVDSE LCPTNYKYVS QNCVTSPMNI DRNITHLQYC VCVDDCSSST CMCGQLSMRC 1080
WYDKDGRLLP EFNMAEPPLI FECNHACSCW RNCRNRVVQN GLRARLQLYR TQDMGWGVRS 1140
LQDIPLGTFV CEYVGELISD SEADVREEDS YLFDLDNKDG EVYCIDARFY GNVSRFINHH 1200
CEPNLVPVRV FMSHQDLRFP RIAFFSTRLI QAGEQLGFDY GERFWDVKGK LFSCRCGSSK 1260
CRHSSAALAQ RQASAAQEPQ ENGLPDTSSA AAADPL 1296
Nucleotide Sequence
(Fasta)		GGCGCGCGGG AGGGGCGGGG CCACGCTGCG GGCCCGGGCC ATGGCCGCCG CTGATGCTGA 60
GCAGGCAGTT CTGGCCAAGC AAGAGACCAA GCAGGATTGC TGCATGAAAA CTGAGCTGCT 120
AAGGGAAGAT ACACCTATGG CTGCTGATGA AGGTTCCACA GAGAAACAAG AAGGAGAGAC 180
TCCCATGGCT GCAGATGGAG AAACAAATGG GTCTTGTGAA AAGAGTGGGG ATCCCAGCCA 240
TCTAAATGCA CCCAAACACA CTCAGGAGAA CACAAGAGCT AGCCCACAGG AAGGCACCAA 300
CAGAGTGTCT CGGGTGGCAG AAAATGGGGT TTCAGAAAGA GACACAGAAG TGGGGAAGCA 360
AAACCATGTC ACAGCTGACG ACTTCATGCA GACATCTGTC ATTGGCAGCA ATGGATATTT 420
CTTAAATAAA CCAGCCCTGC AGGGGCAGCC GTTGAGGACT CCCAACATTC TAACCTCCTC 480
GCTTCCTGGT CATGCTGCAA AAACTCTTCC TGGAGGAGCC AGTAAATGCA GGACTCTGAG 540
TGCACTTCCT CAGACACCAA CCACAGCACC CACTGTGCCT GGGGAAGGGA GTGCAGACAC 600
AGAGGACAGA AAGCCTACAG CCTCGGGCAC TGATGTCAGG GTTCACAGGG CACGCAAGAC 660
CATGCCGAAG TCCATCTTGG GCCTGCATGC AGCCAGCAAA GACCATAGAG AAGTTCAAGA 720
CCATAAGGAA CCAAAAGAGG ATATCAACAG AAACATTTCT GAATGTGGAC GACAGCAGCT 780
TTTACCAACC TTCCCAGCCC TCCACCAGTC GCTACCTCAG AATCAGTGCT ACATGGCCAC 840
CACAAAGTCC CAGACAGCTT GCTTGCCTTT TGTTTTAGCA GCTGCAGTAT CTCGGAAGAA 900
AAAACGAAGA ATGGGAACCT ATAGTTTAGT TCCCAAGAAA AAGACCAAAG TATTAAAACA 960
GAGGACGGTG ATTGAGATGT TTAAAAGCAT AACCCATTCC ACTGTGGGCG CCAAGGGCGA 1020
GAAAGCCTTA GATGATAGTG CCCTGCATGT AAATGGCGAG AGCTTGGAGA TGGACTCAGA 1080
AGATGAAGAC TCCGATGAGC TGGAGGATGA CGAGGACCAT GGAGCTGAGC AAGCGGCTGC 1140
ATTTCCCACC GAGGATAGTA GGACTTCTAA AGAGAGCATG TCTGAGACTG ACCGGGCTGC 1200
AAAGATGGAT GGAGATTCAG AGGAGGAACA GGAGTCTCCC GACACAGGGG AGGATGAAGA 1260
TGGTGGAGAC GAGTCTGACC TGAGTTCTGA ATCCAGTATC AAGAAGAAAT TTCTCAAGAG 1320
GAGAGGGAAG ACTGACAGCC CCTGGATCAA ACCTGCTCGG AAAAGGAGGC GGAGAAGTAG 1380
AAAGAAGCCG AGCAGCATGC TTGGTTCCGA GGCTTGTAAG TCATCTCCAG GAAGCATGGA 1440
GCAGGCAGCT CTGGGAGACA GCGCTGGCTA TATGGAAGTT TCCCTGGATT CCCTGGATCT 1500
CCGTGTCAGA GGAATTCTGT CTTCCCAGAC AGAAAATGAA GGGCTGGCCA GTGGTCCGGA 1560
TGTGCTGGGG ACGGATGGCC TCCAGGAAGT GCCTCTCTGC AGCTGCCGAA TGGAAACCCC 1620
CAAGAGCCGC GAGATCAGCA CCCTGGCCAA CAACCAGTGC ATGGCCACTG AGAGCGTGGA 1680
TCACGAATTG GGCCGGTGTA CAAACAGCGT GGTCAAGTAT GAGCTGATGC GCCCATCCAA 1740
CAAAGCACCG CTCTTGGTGT TATGTGAAGA CCATCGGGGT CGCATGGTGA AGCACCAGTG 1800
CTGTCCTGGC TGCGGCTACT TCTGCACGGC GGGTAACTTC ATGGAATGCC AGCCTGAGAG 1860
CAGCATCTCT CATCGTTTCC ATAAGGACTG TGCCTCTCGA GTCAACAATG CCAGCTACTG 1920
TCCCCATTGT GGGGAAGAAG CTTCCAAGGC CAAAGAGGTG ACCATAGCAA AAGCAGACAC 1980
AACTTCCACA GTGACCCTAG CCCCTGGACA GGAGAAGAGC CTGGCTGCTG AAGGCAGGGC 2040
TGACACGACC ACGGGCAGCA TTGCTGGAGC CCCAGAGGAT GAAAGATCGC AGAGCACAGC 2100
CCCCCAGGCA CCAGAGTGCT TCGACCCTGC CGGACCGGCT GGGCTCGTGA GGCCGACATC 2160
TGGCCTTTCC CAGGGCCCAG GAAAGGAAAC CTTGGAAAGT GCTCTAATCG CTCTAGACTC 2220
TGAAAAACCC AAGAAACTTC GCTTCCACCC AAAGCAGCTG TACTTCTCTG CCAGGCAGGG 2280
TGAGCTGCAG AAGGTGCTTC TCATGCTGGT TGATGGAATT GATCCCAACT TCAAAATGGA 2340
GCACCAAAGT AAGCGTTCCC CATTACATGC TGCTGCGGAG GCTGGCCACG TGGACATCTG 2400
CCACATGCTG GTTCAGGCGG GTGCCAATAT TGACACTTGC TCAGAGGACC AGCGGACCCC 2460
ACTGATGGAG GCTGCAGAGA ACAACCACTT GGATGCAGTG AAGTACCTCA TCAAGGCTGG 2520
AGCACAGGTG GATCCGAAGG ACGCAGAGGG CTCCACATGT TTGCATTTGG CTGCCAAGAA 2580
AGGCCACTAT GATGTGGTTC AGTATCTGCT TTCAAATGGA CAGATGGATG TCAACTGCCA 2640
GGATGACGGT GGATGGACAC CTATGATCTG GGCCACTGAG TACAAGCACG TGGAGCTGGT 2700
GAAGCTGCTG CTGTCTAAGG GCTCTGACAT CAACATCCGG GACAACGAGG AGAACATTTG 2760
TCTGCACTGG GCAGCATTTT CAGGCTGTGT GGACATAGCT GAAATACTTC TGGCTGCCAA 2820
GTGTGACCTG CATGCTGTGA ATATCCATGG AGACTCACCC CTGCACATCG CAGCCAGGGA 2880
GAATCGCTAC GACTGTGTTG TCCTCTTTCT TTCTCGGGAT TCAGATGTTA CTCTGAAAAA 2940
CAAGGAAGGA GAGACTCCCT TGCAGTGTGC AAGTCTCAGT TCGCAGGTGT GGAGTGCATT 3000
GCAGATGAGC AAAGCACTTC GGGACTCAGC CCCTGACAAG CCCGTTGCTG TTGAGAAGAC 3060
GGTGAGCAGG GATATCGCTC GAGGGTATGA GCGCATTCCC ATTCCCTGTG TCAATGCTGT 3120
GGACAGTGAG CTGTGTCCTA CCAACTATAA GTATGTCTCC CAGAACTGTG TGACATCCCC 3180
CATGAACATT GACAGGAACA TCACTCATTT GCAGTACTGC GTGTGTGTAG ATGACTGCTC 3240
CTCTAGCACC TGCATGTGTG GCCAGCTGAG CATGCGCTGC TGGTATGATA AGGATGGCCG 3300
ACTTCTGCCT GAGTTTAACA TGGCAGAACC ACCCTTGATC TTCGAGTGCA ATCATGCCTG 3360
CTCATGCTGG AGGAACTGCC GCAATCGTGT GGTGCAAAAT GGTCTCAGGG CAAGGCTGCA 3420
GCTTTATCGG ACACAGGACA TGGGCTGGGG TGTGCGGTCC CTCCAGGATA TCCCACTGGG 3480
CACCTTTGTC TGCGAATACG TAGGGGAGCT GATTTCGGAC TCTGAAGCTG ATGTTCGGGA 3540
AGAGGACTCT TACCTCTTTG ATCTTGACAA TAAGGATGGA GAGGTATACT GCATTGACGC 3600
TCGGTTCTAT GGGAATGTCA GCCGGTTCAT AAACCACCAC TGCGAACCCA ACCTTGTGCC 3660
TGTGCGAGTG TTCATGTCAC ACCAGGACCT GCGGTTTCCC AGGATTGCCT TCTTCAGTAC 3720
CCGCCTGATT CAGGCTGGGG AGCAGCTCGG GTTCGACTAC GGGGAGCGCT TTTGGGACGT 3780
CAAGGGCAAG CTCTTCAGTT GCCGGTGTGG GTCTTCCAAG TGTCGGCACT CAAGCGCAGC 3840
CCTGGCCCAG AGGCAAGCCA GTGCAGCCCA GGAGCCTCAG GAGAATGGCC TTCCAGATAC 3900
CAGCTCTGCA GCCGCTGCTG ACCCCCTATG AATTGCCAGT GTGGCCAGTG GGACCCTCAA 3960
AATCAGATTC TGGTGACTGC AATTTAGAGA GGAAGAAACT CTACATATGT CCAAGAGGAG 4020
CTGGAGGTAT GGACACCTCT CAGGAATGTT CTGGGCCCGA GGTGTTCATT TAGCTGGCCC 4080
AGTGCTCAGG CCAGAGCATG CCTCTGGGCC TGCACCTCAG AGACCTGGGA CTCCATGTTG 4140
CATAACTTGT GAGTTACTGG TGGTGACTCC GTGCTGCAGC ACTTTCCACG TCTCCCTCTG 4200
GTCTCCGAAG CCCTTGCTCC ACTGCCAGTT TTGTTTGTAT AATGTCTGGT CACGCTCCTG 4260
TATGGCACTC ACCAAGGCCA CCATCACCTA CAAGCTGCTC CGTTAGACCT GCTGCCCACA 4320
GCCTGTGTTG CTGGCACCAG CTCCCATGTG CCACTGGAGG ACACTAGCTC CCTTACAGCC 4380
TTGGAGAGTT TGGCTGACCC ACCACTCATT TTGATGAAAT GTGGGTTTGC TTTTTAAAGA 4440
AACCCTATAT CTAGCCCTAT ATATCAAGCC TCTTACTGGT GTTTCTTTGC TAGGAAGCAG 4500
GTTGGTGTGT GCAGGCAGAC CCTGTACTGG CCCCAGCCAG TTCCGTTGAC GCAGGCACCT 4560
TTGGTTGATT TCTAAGCCAC ACGCTATGAT GATGATGAAT AAACTCGTTT GTTTTTTACC 4620
ATTACTGAAC ATTAGGACAT CAAAGAATAA AAACACAAAA CACAGACAAC GGTGCTGAAT 4680
CTGGTGTGGT CTCTACTCAC CACATGAAAA TAAACTATCA ACTGTAAAAA AAAAAAAAGA 4740
AAAAGAACAA AATGATTTTA GAATAAAGTG CAGGAAAAAC TTTTTTAAAA TGTTAGTCTT 4800
GTAGCTGAAT AAATTTGCCA TCACCTTTTG TGTGGTGGCC GGGCAGGTCA TGTACTTTTT 4860
TTTGGCATAT ACCTTTCTAA ATACTGTAAT TAGTGCAGCG ACAGTGGGTG GTTTTTTTGT 4920
TTTTTGTTTT TCTTTTGTGT GTGTGTGTGT GTGTGTGAGT GTGTGTGACT CTTCTAAAAC 4980
ATTCATAATG CAGTCATGTT TATTTTTTTC TGTTAAAATG TTTTTTGACA GTTTTATGAG 5040
CAGTCTTTTG GCTCAGACCA TTTCTTGTTC TGTTTTCAAT GAAATCAATA AAAAAAAAGT 5100
ACTTTAAATG GAGTTTTCAT TATGACACAT TCTTTCTCTG GGTTTCTGCA AATCCCTAGT 5160
CCTTCCTTTC TGGGTGTACA CTCAGGGGTT ACATGGGTTT CTGGAGGGCT GCCTGTTTGT 5220
TCCTTGTCCG TGTGTTTGGT GCCTGGTGTC CAAGATTGAG AGCCATTCTG AAGGAGCAGG 5280
TGAGTCCCCA TATGCATACG TGAAGGGCTT CATTGGGACA CAGTGATGGT TGACAGAGCC 5340
CAGCTCTTCC CTGCCTGCTG ACAGGTGATG TCTGCAGTCT TCCTTCTAGG GGTCCTAGAC 5400
AAAGCAGCAC CCTGTGCTCC ATGGAGGTCT GGCCTTGCTC ACTACAGGAG GGCTTGTAAG 5460
CTCAATGAAA AATTAATCAA AGGCTCCAGT TTTCAATGCG TGGAGTTCAC TTGGTTAAGC 5520
CTTTTCTAGA AGGAAGGCAG CTGTCTTCAC TTTACAGATA ATCAAGCAGG CCACCTTGGC 5580
TGGTAGGCTG TCCAGTCTAT AGTTCTACCA TCACTGCTGC ATCCTACAGC TGTAGGATGG 5640
CTCTGAGCAG GTGGGATGCT GGTAGACCAG AGAAGGAGTC ATGCCATGCA GGTAGATAGA 5700
AACTGAAGCC CACAGCAGCT CCTCTCCATA GGGTCCCTTC CCTGACTGTG GAATACTCCT 5760
CCTCCATACT GCATTTCTCT CTGTCTCTGT CTCCCCTTCC CTCCCCTCCC TCTCCCCCTC 5820
CCCCCTCCAT GTTAATCAGA TTTGTGTGGT GTTGGGTGTG TTGCGTGCTT CAAGCAGCAT 5880
CAATACCTAA GCTTATACTG ATGAATATGG GCCTATTTCC AAAGTTTCAC TAATAAAAAC 5940
CGTGCTGGAA AAA 5954
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0040--ANK repeat
KW-0156--Chromatin regulator
KW-0158--Chromosome
KW-0181--Complete proteome
KW-1017--Isopeptide bond
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0832--Ubl conjugation
KW-0862--Zinc
--
Interpro

IPR002110--Ankyrin_rpt
IPR020683--Ankyrin_rpt-contain_dom
IPR007728--Pre-SET_dom
IPR001214--SET_dom
PROSITE

PS50297--ANK_REP_REGION
PS50088--ANK_REPEAT
PS50867--PRE_SET
PS50280--SET
Pfam

PF12796--Ank_2
PF05033--Pre-SET
PF00856--SET
Gene Ontology

GO:0005694--C:chromosome
GO:0005654--C:nucleoplasm
GO:0005634--C:nucleus
GO:0070742--F:C2H2 zinc finger domain binding
GO:0046976--F:histone methyltransferase activity (H3-K27 specific)
GO:0046974--F:histone methyltransferase activity (H3-K9 specific)
GO:0018024--F:histone-lysine N-methyltransferase activity
GO:0008168--F:methyltransferase activity
GO:0002039--F:p53 binding
GO:0016279--F:protein-lysine N-methyltransferase activity
GO:0008270--F:zinc ion binding
GO:0016568--P:chromatin modification
GO:0006306--P:DNA methylation
GO:0009790--P:embryo development
GO:0070734--P:histone H3-K27 methylation
GO:0051567--P:histone H3-K9 methylation
GO:0016571--P:histone methylation
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0018027--P:peptidyl-lysine dimethylation
GO:0018026--P:peptidyl-lysine monomethylation
GO:0060992--P:response to fungicide
Orthology
WERAM ID Ensembl Protein ID Species Identity E-value Score
WERAM-Ran-0046 ENSRNOP00000063511.3 Rattus norvegicus 96 0.0 2415
WERAM-Cap-0085 ENSCPOP00000006136.2 Cavia porcellus 89 0.0 2209
WERAM-Hos-0211 ENSP00000417980.1 Homo sapiens 89 0.0 2182
WERAM-Gog-0050 ENSGGOP00000004530.2 Gorilla gorilla 88 0.0 2170
WERAM-Paa-0220 ENSPANP00000017447.1 Papio anubis 89 0.0 2161
WERAM-Aim-0180 ENSAMEP00000017039.1 Ailuropoda melanoleuca 86 0.0 2145
WERAM-Poa-0190 ENSPPYP00000022240.1 Pongo abelii 89 0.0 2140
WERAM-Eqc-0149 ENSECAP00000016801.1 Equus caballus 87 0.0 2139
WERAM-Chs-0200 ENSCSAP00000012911.1 Chlorocebus sabaeus 89 0.0 2138
WERAM-Orc-0169 ENSOCUP00000015109.3 Oryctolagus cuniculus 86 0.0 2134
WERAM-Fec-0013 ENSFCAP00000001127.3 Felis catus 85 0.0 2110
WERAM-Caf-0200 ENSCAFP00000028661.3 Canis familiaris 86 0.0 2102
WERAM-Otg-0003 ENSOGAP00000000118.2 Otolemur garnettii 87 0.0 2095
WERAM-Mup-0174 ENSMPUP00000015170.1 Mustela putorius furo 84 0.0 2050
WERAM-Myl-0132 ENSMLUP00000010608.2 Myotis lucifugus 82 0.0 2044
WERAM-Bot-0117 ENSBTAP00000016118.5 Bos taurus 82 0.0 1982
WERAM-Mod-0151 ENSMODP00000021357.3 Monodelphis domestica 80 0.0 1966
WERAM-Sah-0144 ENSSHAP00000015022.1 Sarcophilus harrisii 79 0.0 1957
WERAM-Dan-0115 ENSDNOP00000014629.3 Dasypus novemcinctus 78 0.0 1905
WERAM-Pat-0181 ENSPTRP00000048599.4 Pan troglodytes 91 0.0 1884
WERAM-Tut-0155 ENSTTRP00000013127.1 Tursiops truncatus 81 0.0 1883
WERAM-Nol-0099 ENSNLEP00000011297.1 Nomascus leucogenys 91 0.0 1851
WERAM-Pes-0039 ENSPSIP00000006137.1 Pelodiscus sinensis 77 0.0 1850
WERAM-Ora-0089 ENSOANP00000015800.2 Ornithorhynchus anatinus 78 0.0 1837
WERAM-Fia-0077 ENSFALP00000005785.1 Ficedula albicollis 75 0.0 1826
WERAM-Tag-0044 ENSTGUP00000002934.1 Taeniopygia guttata 76 0.0 1820
WERAM-Mam-0180 ENSMMUP00000025757.2 Macaca mulatta 90 0.0 1786
WERAM-Anp-0102 ENSAPLP00000012074.1 Anas platyrhynchos 76 0.0 1781
WERAM-Gaga-0086 ENSGALP00000013792.4 Gallus gallus 73 0.0 1764
WERAM-Meg-0025 ENSMGAP00000001979.2 Meleagris gallopavo 73 0.0 1763
WERAM-Anc-0130 ENSACAP00000012109.2 Anolis carolinensis 71 0.0 1702
WERAM-Lac-0126 ENSLACP00000014864.1 Latimeria chalumnae 63 0.0 1545
WERAM-Mim-0095 ENSMICP00000008770.1 Microcebus murinus 77 0.0 1425
WERAM-Loa-0112 ENSLAFP00000009820.3 Loxodonta africana 81 0.0 1323
WERAM-Dar-0065 ENSDARP00000110328.2 Danio rerio 70 0.0 1161
WERAM-Ten-0062 ENSTNIP00000007887.1 Tetraodon nigroviridis 68 0.0 1098
WERAM-Orn-0153 ENSONIP00000016204.1 Oreochromis niloticus 69 0.0 1097
WERAM-Orla-0146 ENSORLP00000017297.1 Oryzias latipes 66 0.0 1096
WERAM-Tar-0120 ENSTRUP00000025101.1 Takifugu rubripes 67 0.0 1088
WERAM-Gaa-0188 ENSGACP00000023866.1 Gasterosteus aculeatus 65 0.0 1087
WERAM-Xim-0080 ENSXMAP00000007374.1 Xiphophorus maculatus 66 0.0 1085
WERAM-Pof-0219 ENSPFOP00000017761.1 Poecilia formosa 66 0.0 1080
WERAM-Sus-0015 ENSSSCP00000001517.1 Sus scrofa 58 0.0 1034
WERAM-Caj-0240 ENSCJAP00000004503.2 Callithrix jacchus 59 0.0 1033
WERAM-Ptv-0045 ENSPVAP00000004855.1 Pteropus vampyrus 59 0.0 1033
WERAM-Ova-0026 ENSOARP00000003659.1 Ovis aries 58 0.0 1033
WERAM-Ict-0151 ENSSTOP00000016647.1 Ictidomys tridecemlineatus 59 0.0 1030
WERAM-Ocp-0041 ENSOPRP00000003534.2 Ochotona princeps 59 0.0 1025
WERAM-Dio-0109 ENSDORP00000010714.1 Dipodomys ordii 59 0.0 1011
WERAM-Asm-0164 ENSAMXP00000016487.1 Astyanax mexicanus 58 0.0 963
WERAM-Xet-0075 ENSXETP00000023873.2 Xenopus tropicalis 65 0.0 784
WERAM-Gam-0065 ENSGMOP00000006394.1 Gadus morhua 63 0.0 741
WERAM-Ere-0111 ENSEEUP00000011871.1 Erinaceus europaeus 56 0.0 686
WERAM-Cis-0009 ENSCSAVP00000000984.1 Ciona savignyi 44 0.0 651
WERAM-Cii-0064 ENSCINP00000028043.2 Ciona intestinalis 56 2e-118 425
WERAM-Drm-0079 FBpp0070062 Drosophila melanogaster 33 3e-118 424
WERAM-Leo-0003 ENSLOCP00000000378.1 Lepisosteus oculatus 79 4e-64 244
WERAM-Viv-0018 VIT_04s0023g00980.t01 Vitis vinifera 44 4e-43 174
WERAM-Orl-0100 KN541022.1_FGP003 Oryza longistaminata 35 3e-42 171
WERAM-Tra-0034 Traes_1DS_5A7302FDE.1 Triticum aestivum 34 5e-42 171
WERAM-Orgl-0089 OGLUM08G14610.1 Oryza glumaepatula 35 6e-42 171
WERAM-Aet-0032 EMT23957 Aegilops tauschii 34 6e-42 171
WERAM-Orm-0086 OMERI08G11900.4 Oryza meridionalis 35 7e-42 170
WERAM-Ors-0082 OS08T0400200-00 Oryza sativa 35 9e-42 170
WERAM-Orr-0095 ORUFI08G15680.1 Oryza rufipogon 35 9e-42 170
WERAM-Tru-0080 TRIUR3_29767-P1 Triticum urartu 34 1e-41 170
WERAM-Orni-0091 ONIVA08G14800.1 Oryza nivara 35 2e-41 169
WERAM-Sei-0063 Si016370m Setaria italica 35 2e-41 169
WERAM-Sob-0077 Sb04g033260.1 Sorghum bicolor 35 2e-41 169
WERAM-Php-0081 PP1S325_74V6.1 Physcomitrella patens 33 2e-41 169
WERAM-Amt-0069 ERN17623 Amborella trichopoda 34 4e-41 168
WERAM-Brd-0079 BRADI3G35330.1 Brachypodium distachyon 34 4e-41 168
WERAM-Orbr-0099 OB08G21670.1 Oryza brachyantha 34 6e-41 167
WERAM-Sot-0063 PGSC0003DMT400054154 Solanum tuberosum 36 5e-40 164
WERAM-Orp-0088 OPUNC08G12520.1 Oryza punctata 34 7e-40 164
WERAM-Hov-0016 MLOC_14516.1 Hordeum vulgare 34 2e-39 162
WERAM-Lep-0048 LPERR04G16570.1 Leersia perrieri 35 2e-39 162
WERAM-Zem-0104 GRMZM2G300955_P01 Zea mays 34 2e-39 162
WERAM-Thc-0036 EOY22741 Theobroma cacao 37 4e-39 161
WERAM-Orb-0045 OBART04G20480.1 Oryza barthii 35 4e-39 161
WERAM-Glm-0122 GLYMA11G04071.1 Glycine max 35 5e-39 161
WERAM-Org-0046 ORGLA04G0175400.1 Oryza glaberrima 35 9e-39 160
WERAM-Ori-0049 BGIOSGA014624-PA Oryza indica 36 1e-38 160
WERAM-Sol-0049 Solyc03g093710.1.1 Solanum lycopersicum 34 1e-38 159
WERAM-Prp-0019 EMJ11616 Prunus persica 35 6e-38 157
WERAM-Met-0121 AES94344 Medicago truncatula 36 1e-37 157
WERAM-Sem-0016 EFJ12590 Selaginella moellendorffii 41 1e-37 157
WERAM-Art-0053 AT2G35160.1 Arabidopsis thaliana 35 2e-37 155
WERAM-Soa-0126 ENSSARP00000012347.1 Sorex araneus 53 3e-37 155
WERAM-Arl-0129 scaffold_402114.1 Arabidopsis lyrata 35 3e-37 155
WERAM-Pot-0091 POPTR_0007s12130.1 Populus trichocarpa 40 5e-37 154
WERAM-Mua-0082 GSMUA_Achr5P08830_001 Musa acuminata 40 1e-36 153
Created Date 25-Jun-2016