WERAM Information

Tag Content
WERAM ID WERAM-Art-0144
Ensembl Protein ID AT5G56740.1
Uniprot Accession Q9FJT8; HATB_ARATH; Q8LKJ6;
Genbank Protein ID NP_200485.1;
Protein Name
Genbank Nucleotide ID NM_125057.3;
Gene Name HAG2;HATB;HAT1;At5g56740;MIK19.19
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
AT5G56740 AT5G56740.1 AT5G56740.1
Details
Type Family Domain Substrates AA References (PMIDs)
HAT HAT1 H4K12 K 26689639
Status Reviewed
Classification
Type Family E-value Score Start End
HAT HAT1 5.70e-53 180.2 29 293
Organism Arabidopsis thaliana
NCBI Taxa ID 3702
Functional Description
(View)		 Acetylates soluble but not nucleosomal H4 (By similarity). Acetylates 'Lys-12' of histone H4.
Domain Profile
  HAT HAT1
     HAT1.txt   2 vveanevielllveakeeid.tdistfkpeilyqlfgddetifGYkdlkvtvhylaksldeyidvkYsskinkekgscleaddveskleqkiteetiv 98 
                  +veane+i+++lv++kee+d +dis++kp++l+++f++d++i+GY++lk++v+++++sl++y+d++Y+s+in++kg    ++d++s+l++ i++etiv
  AT5G56740.1  29 GVEANECIKIYLVSSKEEVDsSDISSVKPVDLNDFFDGDGKIYGYQGLKINVWINSISLHSYADITYQSTINGDKG----ITDLKSALQN-IFAETIV 121
                  689*************************************************************************....**********.******* PP
     HAT1.txt  99 dnkeeFlqlldkqddF....kpfgelihkyrklgkd.........feiykaedlsdeflellerlqtlelfFie 159
                  d+k+eFlq++++q+dF    +++ge++h+++++g++         ++++++e+ s+++++l++rl++l+l+F++
  AT5G56740.1 122 DTKDEFLQTFSTQRDFirnmVSNGEVMHAGATDGSSknaevvpsdPQVIRMEIGSPNAGLLYSRLVPLVLLFVD 195
                  *************************************************************************8 PP
     HAT1.txt  87 kleqkiteetivdnkeeFlqll 108
                  ++ +++ + t++++ e+F++ +
  AT5G56740.1 272 AITENVYDLTVEEPSEKFQHIR 293
                  5667799999999999999765 PP
Protein Sequence
(Fasta)		MVQKQQASAG PGTEPKKRRR VGFSPADTGV EANECIKIYL VSSKEEVDSS DISSVKPVDL 60
NDFFDGDGKI YGYQGLKINV WINSISLHSY ADITYQSTIN GDKGITDLKS ALQNIFAETI 120
VDTKDEFLQT FSTQRDFIRN MVSNGEVMHA GATDGSSKNA EVVPSDPQVI RMEIGSPNAG 180
LLYSRLVPLV LLFVDGSNPI DVTDPDWHLY LLIQKKEEKE DPLYRIVGFT AIYKFYRYPD 240
RLRMRLSQIL VLPSFQGKGL GSYLMEVVNN VAITENVYDL TVEEPSEKFQ HIRTCIDINR 300
LRSFDPIKPD IDSAVQTLTK GKLSKKAQIP RFTPPLNAIE KVRESLKINK KQFLKCWEIL 360
IYLALDPIDK YMEDYTSVIT NHVRTDILGK DIETPKKQVV DVPSSFEPEA SFVVFKSVNG 420
EEANTNVQVD ENKPDQEQQL KQLVEERIRE IKLVAEKVSK SGQTLKV 467
Nucleotide Sequence
(Fasta)		GTATCGCTCT CTCCGCATTT CCATTAACCC TCCAATTTTC CCGCCTTTGT CTCACTCTCT 60
TCCCGCCTTG CACTCGCCGG GGACTCCATG GTTCAGAAGC AGCAAGCCTC CGCCGGTCCG 120
GGTACCGAGC CTAAGAAGCG TCGCCGTGTC GGATTTTCTC CCGCCGATAC TGGTGTCGAG 180
GCTAACGAGT GCATCAAAAT TTATCTCGTT TCAAGCAAAG AGGAAGTTGA TTCCTCTGAT 240
ATTTCCAGCG TGAAGCCAGT TGACTTGAAT GATTTCTTTG ATGGAGATGG CAAGATTTAT 300
GGTTACCAAG GTTTGAAGAT AAATGTATGG ATCAATAGCA TCTCATTACA TTCATATGCT 360
GATATCACAT ACCAGAGCAC CATTAACGGA GACAAAGGCA TCACGGACCT CAAATCTGCT 420
TTACAGAACA TATTTGCTGA GACCATTGTT GATACCAAGG ATGAGTTTCT GCAAACCTTT 480
TCGACACAGA GAGATTTTAT CAGAAATATG GTCTCGAATG GAGAGGTAAT GCATGCTGGA 540
GCAACAGATG GAAGCAGCAA GAATGCTGAA GTGGTTCCTT CTGATCCCCA GGTTATACGG 600
ATGGAAATTG GTTCTCCAAA TGCTGGACTC CTCTATAGCC GATTGGTACC CCTTGTTCTT 660
CTTTTTGTCG ATGGCAGCAA TCCGATTGAT GTCACTGATC CTGACTGGCA TTTATATCTC 720
TTAATCCAGA AGAAAGAGGA AAAAGAAGAT CCTTTGTATC GAATTGTGGG CTTTACCGCA 780
ATTTATAAGT TCTATCGTTA TCCTGACAGG CTGCGGATGC GACTCAGCCA GATCTTGGTC 840
TTACCATCCT TCCAAGGAAA AGGACTCGGA AGCTATCTTA TGGAGGTAGT AAACAACGTG 900
GCCATAACAG AAAACGTTTA CGATTTGACA GTTGAGGAGC CATCTGAAAA GTTCCAACAC 960
ATCCGCACTT GCATAGACAT AAACCGCTTG CGCAGTTTCG ATCCAATCAA ACCAGACATT 1020
GATTCAGCTG TTCAGACTCT CACAAAAGGA AAGCTATCAA AGAAAGCTCA GATACCTCGA 1080
TTCACCCCGC CTCTGAACGC CATTGAGAAA GTCCGCGAAT CTCTGAAGAT CAACAAGAAA 1140
CAGTTCCTCA AATGCTGGGA GATTTTGATA TACCTTGCTC TTGATCCTAT TGACAAGTAC 1200
ATGGAAGATT ACACATCAGT CATCACGAAC CATGTGAGAA CCGACATTCT GGGAAAAGAT 1260
ATAGAAACTC CAAAGAAACA AGTCGTTGAT GTTCCAAGCT CTTTCGAGCC AGAAGCATCG 1320
TTTGTGGTTT TCAAGTCTGT AAACGGAGAA GAGGCTAATA CCAATGTTCA AGTTGATGAA 1380
AACAAACCGG ATCAAGAGCA GCAGCTGAAG CAACTTGTTG AGGAAAGGAT TCGTGAGATC 1440
AAGTTGGTTG CTGAGAAAGT CTCCAAGAGT GGTCAAACGC TAAAAGTCTG ATTGGAATCA 1500
AAACTTTGTG AGTCTTTTAT CGGAAGTTTT TTGTTGAATG ATCAAACTAG AAATCTCAAA 1560
CTTTGTTGAT CTTCTGTAAG GAGTAAGGAC AAATCTGTTT GTAGCGCTAT GTTATGGAAG 1620
TTGAGTAAAC TAATGTAGTT CCGGTTATGA TGTTTGTTGT CACATCCAGA ACCATAAATT 1680
GGAATATTCC GATTGAATTT TAGC 1705
Sequence Source Ensembl
Keyword

KW-0012--Acyltransferase
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0808--Transferase
--
Interpro

IPR016181--Acyl_CoA_acyltransferase
IPR000182--GNAT_dom
IPR019467--Hat1_N
IPR017380--Hist_AcTrfase_B-typ_cat-su
PROSITE
Pfam

PF00583--Acetyltransf_1
PF10394--Hat1_N
Gene Ontology

GO:0000781--C:chromosome, telomeric region
GO:0005829--C:cytosol
GO:0000790--C:nuclear chromatin
GO:0005634--C:nucleus
GO:0010485--F:H4 histone acetyltransferase activity
GO:0042393--F:histone binding
GO:0006348--P:chromatin silencing at telomere
GO:0043967--P:histone H4 acetylation
Orthology
WERAM ID Ensembl Protein ID Species Identity E-value Score
WERAM-Orla-0189 ENSORLP00000021710.1 Oryzias latipes 25 3e-26 117
WERAM-Mod-0069 ENSMODP00000011048.3 Monodelphis domestica 25 3e-26 117
WERAM-Orn-0101 ENSONIP00000010967.1 Oreochromis niloticus 26 4e-26 117
WERAM-Pes-0131 ENSPSIP00000015233.1 Pelodiscus sinensis 25 4e-26 116
WERAM-Meg-0104 ENSMGAP00000010389.2 Meleagris gallopavo 24 1e-25 115
WERAM-Tag-0111 ENSTGUP00000008605.1 Taeniopygia guttata 25 2e-25 114
WERAM-Sah-0179 ENSSHAP00000018728.1 Sarcophilus harrisii 24 2e-25 114
WERAM-Ten-0201 ENSTNIP00000002170.1 Tetraodon nigroviridis 26 3e-25 113
WERAM-Fia-0035 ENSFALP00000002091.1 Ficedula albicollis 25 3e-25 113
WERAM-Anp-0011 ENSAPLP00000002164.1 Anas platyrhynchos 24 4e-25 113
WERAM-Gaga-0098 ENSGALP00000015492.3 Gallus gallus 24 4e-25 113
WERAM-Lac-0041 ENSLACP00000006166.2 Latimeria chalumnae 26 5e-25 112
WERAM-Soa-0052 ENSSARP00000005106.1 Sorex araneus 25 8e-25 112
WERAM-Myl-0187 ENSMLUP00000015650.2 Myotis lucifugus 27 1e-24 112
WERAM-Caf-0137 ENSCAFP00000018999.3 Canis familiaris 25 2e-24 111
WERAM-Ova-0012 ENSOARP00000001849.1 Ovis aries 25 2e-24 110
WERAM-Bot-0100 ENSBTAP00000013355.2 Bos taurus 25 2e-24 110
WERAM-Aim-0094 ENSAMEP00000008940.1 Ailuropoda melanoleuca 25 2e-24 110
WERAM-Fec-0026 ENSFCAP00000002278.3 Felis catus 25 3e-24 110
WERAM-Ran-0015 ENSRNOP00000002085.5 Rattus norvegicus 24 3e-24 110
WERAM-Dan-0092 ENSDNOP00000009190.3 Dasypus novemcinctus 25 5e-24 109
WERAM-Vip-0017 ENSVPAP00000001693.1 Vicugna pacos 25 5e-24 109
WERAM-Ptv-0121 ENSPVAP00000010680.1 Pteropus vampyrus 25 8e-24 108
WERAM-Drm-0060 FBpp0078318 Drosophila melanogaster 28 1e-23 108
WERAM-Sus-0118 ENSSSCP00000016904.2 Sus scrofa 25 1e-23 108
WERAM-Mum-0084 ENSMUSP00000028408.2 Mus musculus 25 1e-23 108
WERAM-Eqc-0073 ENSECAP00000009282.1 Equus caballus 24 1e-23 108
WERAM-Otg-0107 ENSOGAP00000009328.2 Otolemur garnettii 25 2e-23 107
WERAM-Poa-0112 ENSPPYP00000014436.2 Pongo abelii 25 3e-23 107
WERAM-Nol-0056 ENSNLEP00000006694.2 Nomascus leucogenys 25 3e-23 107
WERAM-Pat-0100 ENSPTRP00000021597.3 Pan troglodytes 25 3e-23 107
WERAM-Gog-0106 ENSGGOP00000009140.2 Gorilla gorilla 25 3e-23 107
WERAM-Chs-0180 ENSCSAP00000010905.1 Chlorocebus sabaeus 25 3e-23 107
WERAM-Paa-0093 ENSPANP00000018512.1 Papio anubis 25 7e-23 105
WERAM-Cae-0071 M03C11.4.2 Caenorhabditis elegans 25 9e-23 105
WERAM-Hos-0115 ENSP00000264108.4 Homo sapiens 25 9e-23 105
WERAM-Mam-0057 ENSMMUP00000009587.2 Macaca mulatta 26 1e-22 104
WERAM-Caj-0083 ENSCJAP00000013707.2 Callithrix jacchus 24 1e-22 104
WERAM-Orc-0047 ENSOCUP00000004608.2 Oryctolagus cuniculus 25 2e-22 104
WERAM-Loa-0101 ENSLAFP00000008558.3 Loxodonta africana 25 3e-22 103
WERAM-Sac-0045 YPL001W Saccharomyces cerevisiae 26 6e-22 102
WERAM-Cap-0017 ENSCPOP00000001664.2 Cavia porcellus 26 7e-22 102
WERAM-Mup-0007 ENSMPUP00000000831.1 Mustela putorius furo 26 9e-22 102
WERAM-Ocp-0137 ENSOPRP00000014189.1 Ochotona princeps 26 2e-21 100
WERAM-Scp-0004 SPAC139.06.1:pep Schizosaccharomyces pombe 26 1e-19 95.5
Created Date 25-Jun-2016