| Tag |
Content |
| WERAM ID |
WERAM-Art-0128 |
| Ensembl Protein ID |
AT5G24330.1 |
| Uniprot Accession |
Q9FNE9; ATXR6_ARATH
|
| Genbank Protein ID |
NP_197821.1
|
| Protein Name |
Histone-lysine N-methyltransferase ATXR6 |
| Genbank Nucleotide ID |
NM_122341.2
|
| Gene Name |
ATXR6 |
| Ensembl Information |
|
| Details |
|
| Status |
Reviewed |
| Classification |
| Type |
Family |
E-value |
Score |
Start |
End |
| HMT |
SET1 |
6.80e-34 |
117.3 |
215 |
337 |
| Me_Reader |
PHD |
6.60e-11 |
43 |
33 |
81 |
|
| Organism |
Arabidopsis thaliana |
| NCBI Taxa ID |
3702 |
Functional Description
(View)Functional Description
Histone methyltransferase that specifically monomethylates 'Lys-37' of histone H3 (H3K27me1). Has higher activity on nucleosomes containing H3.1 than H3.3. Involved in the formation of constitutive heterochromatin and the silencing of heterochromatic elements. May act as a positive regulator of the G1-S transition. Influences which sets of rRNA gene variants are expressed or silenced. Up-regulated by E2FB. |
Histone methyltransferase that specifically monomethylates 'Lys-37' of histone H3 (H3K27me1). Has higher activity on nucleosomes containing H3.1 than H3.3. Involved in the formation of constitutive heterochromatin and the silencing of heterochromatic elements. May act as a positive regulator of the G1-S transition. Influences which sets of rRNA gene variants are expressed or silenced. Up-regulated by E2FB.
|
| Domain Profile |
HMT SET1
SET1.txt 2 elevakskikglglvakkeiekeelviEYvGevirsevadkrekeyekkeigvylfrldedaevvvdatkkgniarfi....nhsce....pNceakv 91
+l+v++++++g++++a++ i+++++++EYvG+v ++ ++re++y+ ++++++l+++d+++++v+++++++niarfi nhs+e +N+++ +
AT5G24330.1 215 PLMVVFDPYEGFTVEADRFIKDWTIITEYVGDV---DYLSNREDDYDGDSMMTLLHASDPSQCLVICPDRRSNIARFIsginNHSPEgrkkQNLKCVR 309
799******************************...**************************************************99999******* PP
SET1.txt 92 vavdgekkiviyakraIekgeeltydYk 119
++++ge++++++a+r+I+kge+l+ydY+
AT5G24330.1 310 FNINGEARVLLVANRDISKGERLYYDYN 337
***************************7 PP
Me_Reader PHD
PHD.txt 2 tiClvCgkddegekemvqCdeCddwfHlkCvklplsslpegkswyCpsCke 52
t+C C+ ++ + +++ Cd+Cd+ fHl C+ + l s+p+g sw+CpsC +
AT5G24330.1 33 TVCEECSSGKQPA-KLLLCDKCDKGFHLFCLRPILVSVPKG-SWFCPSCSK 81
7899995555554.4**************************.*******86 PP
|
Protein Sequence
(Fasta) | MVAVRRRRTQ ASNPRSEPPQ HMSDHDSDSD WDTVCEECSS GKQPAKLLLC DKCDKGFHLF 60
CLRPILVSVP KGSWFCPSCS KHQIPKSFPL IQTKIIDFFR IKRSPDSSQI SSSSDSIGKK 120
RKKTSLVMSK KKRRLLPYNP SNDPQRRLEQ MASLATALRA SNTKFSNELT YVSGKAPRSA 180
NQAAFEKGGM QVLSKEGVET LALCKKMMDL GECPPLMVVF DPYEGFTVEA DRFIKDWTII 240
TEYVGDVDYL SNREDDYDGD SMMTLLHASD PSQCLVICPD RRSNIARFIS GINNHSPEGR 300
KKQNLKCVRF NINGEARVLL VANRDISKGE RLYYDYNGYE HEYPTEHFV 349Protein Fasta Sequence
>AT5G24330.1|ATXR6|Arabidopsis thaliana
MVAVRRRRTQASNPRSEPPQHMSDHDSDSDWDTVCEECSSGKQPAKLLLCDKCDKGFHLFCLRPILVSVPKGSWFCPSCSKHQIPKSFPLIQTKIIDFFRIKRSPDSSQISSSSDSIGKKRKKTSLVMSKKKRRLLPYNPSNDPQRRLEQMASLATALRASNTKFSNELTYVSGKAPRSANQAAFEKGGMQVLSKEGVETLALCKKMMDLGECPPLMVVFDPYEGFTVEADRFIKDWTIITEYVGDVDYLSNREDDYDGDSMMTLLHASDPSQCLVICPDRRSNIARFISGINNHSPEGRKKQNLKCVRFNINGEARVLLVANRDISKGERLYYDYNGYEHEYPTEHFV |
Nucleotide Sequence
(Fasta) | AACCTCGGCT AGATCTCACA TTTATAATCT CTCACTCTCT CTCTTTCTCT GGTAAATCAA 60
TAAGTGTAAG AATGGTGGCT GTGAGGCGAA GGAGAACACA AGCGTCAAAC CCTAGATCCG 120
AACCACCGCA ACACATGTCG GATCATGATT CCGATTCCGA TTGGGATACA GTCTGCGAAG 180
AATGCAGTTC CGGTAAACAA CCAGCAAAGC TGCTTCTTTG CGACAAATGC GATAAAGGGT 240
TTCATCTTTT CTGTCTCAGA CCGATCCTCG TTTCAGTTCC CAAAGGCTCT TGGTTCTGCC 300
CTTCTTGTTC CAAACATCAG ATCCCTAAAT CTTTCCCTCT TATTCAGACT AAAATTATAG 360
ATTTCTTCCG GATTAAGCGG TCTCCAGATT CATCTCAAAT CTCAAGTTCT TCAGATAGTA 420
TTGGGAAGAA ACGGAAAAAG ACTAGCTTGG TGATGTCAAA GAAGAAGAGA AGGCTTCTTC 480
CATACAATCC TAGCAATGAT CCTCAAAGGA GGCTAGAGCA AATGGCGTCT CTGGCCACTG 540
CGTTGAGAGC TTCCAACACC AAGTTCAGCA ATGAGCTTAC TTATGTATCT GGAAAGGCTC 600
CAAGATCTGC AAACCAAGCT GCTTTTGAGA AAGGAGGCAT GCAGGTTCTA TCTAAAGAAG 660
GCGTAGAGAC CTTAGCCTTG TGCAAGAAAA TGATGGACCT CGGTGAATGC CCGCCACTTA 720
TGGTCGTCTT CGATCCTTAT GAAGGGTTCA CAGTAGAGGC GGACAGGTTT ATAAAAGACT 780
GGACAATTAT CACAGAGTAT GTTGGAGATG TTGATTATCT GAGCAATAGA GAAGATGACT 840
ATGATGGAGA CAGTATGATG ACTCTACTTC ATGCCTCTGA TCCTTCGCAA TGTCTCGTAA 900
TTTGCCCTGA CAGACGCAGT AACATCGCCC GGTTCATCAG TGGCATCAAC AATCACTCAC 960
CAGAAGGGAG GAAGAAGCAG AACCTGAAGT GTGTGAGGTT CAACATCAAC GGAGAAGCTA 1020
GGGTTCTTCT CGTAGCTAAT AGAGACATAT CGAAAGGGGA AAGATTGTAT TATGATTACA 1080
ACGGATATGA ACATGAGTAT CCAACTGAAC ATTTTGTATA ACCCTGTGAA TTTCGTAAGA 1140
AAGGTCAACC TATTAAAAAG GTTGCTTGTT CATCAAGAAA CAACCTAAAA GTGTTTTTTG 1200
TCCTTCCTAA TGCTTTAAC
Nucleotide Fasta Sequence
>AT5G24330.1|PHD|Arabidopsis thaliana
AACCTCGGCTAGATCTCACATTTATAATCTCTCACTCTCTCTCTTTCTCTGGTAAATCAATAAGTGTAAGAATGGTGGCTGTGAGGCGAAGGAGAACACAAGCGTCAAACCCTAGATCCGAACCACCGCAACACATGTCGGATCATGATTCCGATTCCGATTGGGATACAGTCTGCGAAGAATGCAGTTCCGGTAAACAACCAGCAAAGCTGCTTCTTTGCGACAAATGCGATAAAGGGTTTCATCTTTTCTGTCTCAGACCGATCCTCGTTTCAGTTCCCAAAGGCTCTTGGTTCTGCCCTTCTTGTTCCAAACATCAGATCCCTAAATCTTTCCCTCTTATTCAGACTAAAATTATAGATTTCTTCCGGATTAAGCGGTCTCCAGATTCATCTCAAATCTCAAGTTCTTCAGATAGTATTGGGAAGAAACGGAAAAAGACTAGCTTGGTGATGTCAAAGAAGAAGAGAAGGCTTCTTCCATACAATCCTAGCAATGATCCTCAAAGGAGGCTAGAGCAAATGGCGTCTCTGGCCACTGCGTTGAGAGCTTCCAACACCAAGTTCAGCAATGAGCTTACTTATGTATCTGGAAAGGCTCCAAGATCTGCAAACCAAGCTGCTTTTGAGAAAGGAGGCATGCAGGTTCTATCTAAAGAAGGCGTAGAGACCTTAGCCTTGTGCAAGAAAATGATGGACCTCGGTGAATGCCCGCCACTTATGGTCGTCTTCGATCCTTATGAAGGGTTCACAGTAGAGGCGGACAGGTTTATAAAAGACTGGACAATTATCACAGAGTATGTTGGAGATGTTGATTATCTGAGCAATAGAGAAGATGACTATGATGGAGACAGTATGATGACTCTACTTCATGCCTCTGATCCTTCGCAATGTCTCGTAATTTGCCCTGACAGACGCAGTAACATCGCCCGGTTCATCAGTGGCATCAACAATCACTCACCAGAAGGGAGGAAGAAGCAGAACCTGAAGTGTGTGAGGTTCAACATCAACGGAGAAGCTAGGGTTCTTCTCGTAGCTAATAGAGACATATCGAAAGGGGAAAGATTGTATTATGATTACAACGGATATGAACATGAGTATCCAACTGAACATTTTGTATAACCCTGTGAATTTCGTAAGAAAGGTCAACCTATTAAAAAGGTTGCTTGTTCATCAAGAAACAACCTAAAAGTGTTTTTTGTCCTTCCTAATGCTTTAAC
|
| Sequence Source |
Ensembl |
| Keyword |
KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger
--
|
| Interpro |
IPR001214--SET_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD
|
| PROSITE |
PS50280--SET
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2
|
| Pfam |
PF00628--PHD
PF00856--SET
|
| Gene Ontology |
GO:0005634--C:nucleus
GO:0046976--F:histone methyltransferase activity (H3-K27 specific)
GO:0008270--F:zinc ion binding
GO:0009901--P:anther dehiscence
GO:0070734--P:histone H3-K27 methylation
GO:0051726--P:regulation of cell cycle
GO:0006275--P:regulation of DNA replication
|
| Orthology |
|
| Created Date |
25-Jun-2016 |
