| Tag |
Content |
| WERAM ID |
WERAM-Art-0064 |
| Ensembl Protein ID |
AT3G04380.1 |
| Uniprot Accession |
Q8W595; SUVR4_ARATH; Q3EBC4; Q9M848
|
| Genbank Protein ID |
NP_187088.2
|
| Protein Name |
Histone-lysine N-methyltransferase SUVR4 |
| Genbank Nucleotide ID |
NM_111309.2
|
| Gene Name |
SUVR4 |
| Ensembl Information |
|
| Details |
| Type |
Family |
Domain |
Substrates |
AA |
References (PMIDs) |
| HMT |
SUV39 |
SET |
H3K9 |
K |
22549957; 20703330
|
|
| Status |
Reviewed |
| Classification |
| Type |
Family |
E-value |
Score |
Start |
End |
| HMT |
SUV39 |
1.20e-37 |
129.9 |
89 |
434 |
|
| Organism |
Arabidopsis thaliana |
| NCBI Taxa ID |
3702 |
Functional Description
(View)Functional Description
Histone methyltransferase that converts monomethylated 'Lys-9' of histone H3 (H3K9me1) to dimethylated 'Lys-9' (H3K9me2) in the absence of bound ubiquitin, and to trimethylated 'Lys-9' (H3K9me3) in the presence of bound ubiquitin. Acts in a locus-specific manner and contributes to the transcriptional silencing of pseudogenes and transposons. H3 'Lys-9' methylation represents a specific tag for epigenetic transcriptional repression. |
Histone methyltransferase that converts monomethylated 'Lys-9' of histone H3 (H3K9me1) to dimethylated 'Lys-9' (H3K9me2) in the absence of bound ubiquitin, and to trimethylated 'Lys-9' (H3K9me3) in the presence of bound ubiquitin. Acts in a locus-specific manner and contributes to the transcriptional silencing of pseudogenes and transposons. H3 'Lys-9' methylation represents a specific tag for epigenetic transcriptional repression.
|
| Domain Profile |
HMT SUV39
SUV39.txt 46 eegdeyladldskesvenlkegyesdvplssdssn 80
+++ + ++l+ ++s + lk++ye++ + s s +
AT3G04380.1 89 SSNGNRGKNLKVIDSPATLKKTYETRSASSGSSIQ 123
34444556666666666666666666665555543 PP
SUV39.txt 2 rLqvfktenk.GwGvrclddiakgsFvciyaGeiltddeaekegl...eegdeyladldskesvenlkegyesdvplssdssntrqekdkeeseyiid 95
+Lqv+ t++ GwG+r+l+d++kg+F+c+y+Geilt++e ++++ +e+++y ++ld+ + +++ k+e+ +++d
AT3G04380.1 303 QLQVYFTQEGkGWGLRTLQDLPKGTFICEYIGEILTNTELYDRNVrssSERHTYPVTLDADWG---------------------SEKDLKDEEALCLD 379
79***999977****************************999966545666667777777554.....................345668899***** PP
SUV39.txt 96 akkegnvgrflnHsc.spNlfvqnvfvdthdlrfprvafFaskrikagtELtwdY 149
a+ gnv+rf+nH+c ++N++ ++ ++t d++++++afF+ +++ka++ELtwdY
AT3G04380.1 380 ATICGNVARFINHRCeDANMIDIPIEIETPDRHYYHIAFFTLRDVKAMDELTWDY 434
***************99************************************** PP
|
Protein Sequence
(Fasta) | MISLSGLTSS VESDLDMQQA MLTNKDEKVL KALERTRQLD IPDEKTMPVL MKLLEEAGGN 60
WSYIKLDNYT ALVDAIYSVE DENKQSEGSS NGNRGKNLKV IDSPATLKKT YETRSASSGS 120
SIQVVQKQPQ LSNGDRKRKY KSRIADITKG SESVKIPLVD DVGSEAVPKF TYIPHNIVYQ 180
SAYLHVSLAR ISDEDCCANC KGNCLSADFP CTCARETSGE YAYTKEGLLK EKFLDTCLKM 240
KKEPDSFPKV YCKDCPLERD HDKGTYGKCD GHLIRKFIKE CWRKCGCDMQ CGNRVVQRGI 300
RCQLQVYFTQ EGKGWGLRTL QDLPKGTFIC EYIGEILTNT ELYDRNVRSS SERHTYPVTL 360
DADWGSEKDL KDEEALCLDA TICGNVARFI NHRCEDANMI DIPIEIETPD RHYYHIAFFT 420
LRDVKAMDEL TWDYMIDFND KSHPVKAFRC CCGSESCRDR KIKGSQGKSI ERRKIVSAKK 480
QQGSKEVSKK RK 492Protein Fasta Sequence
>AT3G04380.1|SUVR4|Arabidopsis thaliana
MISLSGLTSSVESDLDMQQAMLTNKDEKVLKALERTRQLDIPDEKTMPVLMKLLEEAGGNWSYIKLDNYTALVDAIYSVEDENKQSEGSSNGNRGKNLKVIDSPATLKKTYETRSASSGSSIQVVQKQPQLSNGDRKRKYKSRIADITKGSESVKIPLVDDVGSEAVPKFTYIPHNIVYQSAYLHVSLARISDEDCCANCKGNCLSADFPCTCARETSGEYAYTKEGLLKEKFLDTCLKMKKEPDSFPKVYCKDCPLERDHDKGTYGKCDGHLIRKFIKECWRKCGCDMQCGNRVVQRGIRCQLQVYFTQEGKGWGLRTLQDLPKGTFICEYIGEILTNTELYDRNVRSSSERHTYPVTLDADWGSEKDLKDEEALCLDATICGNVARFINHRCEDANMIDIPIEIETPDRHYYHIAFFTLRDVKAMDELTWDYMIDFNDKSHPVKAFRCCCGSESCRDRKIKGSQGKSIERRKIVSAKKQQGSKEVSKKRK |
Nucleotide Sequence
(Fasta) | CGCACGACGC AGTGAAACAG AGATACTGTG GAAAAGTGTG TTTAAAATGG ATCTGTTTTA 60
GGGTATTTAT CAATTCGAAA ATTGATTAAT TTATTAATTT CGTAAGCTTT CACAGAAAGT 120
TCGAACTCTT TGCATGCAAT CATTCGCCGT CTTCTTCCAC AATTGTGTTT TTTAGCCGGC 180
GGCGGCTGGA TTCGAGAAGC TTCCGATTGT TCTGTATGAT CAGTCTCTCC GGACTAACCA 240
GTTCTGTTGA AAGTGATCTC GATATGCAAC AAGCGATGCT CACCAATAAA GACGAGAAGG 300
TACTCAAAGC TTTAGAGAGA ACAAGGCAAT TGGATATTCC CGATGAAAAG ACAATGCCAG 360
TGCTTATGAA GCTCCTAGAA GAGGCTGGTG GCAATTGGTC GTATATAAAG TTGGATAACT 420
ATACTGCACT GGTCGACGCT ATTTATTCTG TTGAGGATGA GAATAAGCAA AGTGAAGGTT 480
CATCTAATGG TAATAGAGGG AAGAATCTTA AGGTCATTGA CTCTCCTGCT ACTCTGAAAA 540
AAACTTACGA AACCCGTTCT GCATCCTCAG GTTCCTCCAT TCAGGTAGTC CAGAAGCAGC 600
CACAGCTTAG TAATGGTGAT CGCAAGAGGA AATATAAAAG CAGAATTGCT GACATAACTA 660
AAGGTTCAGA GAGCGTTAAA ATCCCTCTTG TCGATGATGT TGGGAGTGAA GCTGTGCCAA 720
AGTTTACTTA CATCCCTCAC AACATTGTTT ACCAAAGTGC TTATCTCCAC GTGTCTCTGG 780
CTCGAATCTC TGATGAAGAT TGCTGCGCAA ACTGCAAAGG GAACTGTCTT TCAGCTGACT 840
TTCCTTGCAC TTGTGCTCGT GAAACCAGTG GAGAATATGC TTATACCAAA GAAGGGCTGC 900
TAAAGGAAAA GTTTCTGGAC ACCTGTCTTA AGATGAAAAA GGAACCAGAT TCGTTCCCTA 960
AAGTTTACTG CAAAGACTGC CCTTTGGAGA GAGATCACGA TAAGGGCACA TATGGAAAAT 1020
GTGATGGACA CTTAATCCGA AAGTTCATCA AGGAATGCTG GAGAAAGTGT GGATGTGATA 1080
TGCAGTGTGG AAATCGAGTA GTACAGAGAG GGATAAGGTG CCAACTGCAG GTTTACTTTA 1140
CTCAAGAAGG GAAAGGATGG GGTCTTAGAA CACTGCAAGA CTTGCCCAAA GGAACCTTTA 1200
TCTGTGAATA CATTGGTGAA ATATTGACCA ACACGGAGTT ATACGATCGG AATGTTAGGT 1260
CTAGTAGTGA ACGACATACA TATCCTGTAA CTCTGGATGC AGACTGGGGT TCTGAAAAGG 1320
ATCTAAAAGA TGAAGAAGCT CTCTGCCTGG ATGCCACAAT CTGTGGAAAT GTCGCAAGGT 1380
TTATCAATCA CAGATGCGAG GATGCAAACA TGATTGATAT TCCGATAGAG ATAGAGACGC 1440
CTGACAGACA TTATTATCAT ATTGCTTTTT TTACCCTACG AGACGTGAAG GCCATGGATG 1500
AGTTGACATG GGATTACATG ATAGACTTCA ATGATAAAAG TCATCCTGTA AAGGCATTTA 1560
GATGTTGCTG CGGAAGCGAA TCATGCAGAG ACAGAAAAAT AAAAGGATCT CAAGGCAAGT 1620
CTATAGAGAG AAGAAAGATT GTTTCTGCTA AAAAACAACA AGGTTCCAAA GAGGTGTCTA 1680
AAAAGCGCAA ATGAGACTGG TCATTATTTA GAGTTAAACA TTAAAGAAAG CATGAGCTCA 1740
CAAAACACTA TGATCCATCG CGAGCTCTGC ATGATTCAAC TAGCTTTTCC TTCTTGATGA 1800
CATATACAAC TTTTATGGTC TGCAGTTTTT TCTCATTTAC AATCTCTTCT TTAGGTAAAA 1860
AAAAGTGTTA TGTTGCCTAA CCAAAGAAAC TCACTGTTTA GTTCTGTTCT TCAAATTTCA 1920
TGGCATATGT CAAAATAAAT AAACCTTTTT TAATAGAGTT CTAGAGCGTA AAGACTGGAT 1980
CGAAAAGGAG CCCATCACTG GTAAATTCAG CCAAGAGTGA TCCATCGCAT CAATGATTTG 2040
TAATGTTAAA CAAAATTTTA ATATTTAGAC TTAGAAGTTG TAAT
2085Nucleotide Fasta Sequence
>AT3G04380.1|SUV39|Arabidopsis thaliana
CGCACGACGCAGTGAAACAGAGATACTGTGGAAAAGTGTGTTTAAAATGGATCTGTTTTAGGGTATTTATCAATTCGAAAATTGATTAATTTATTAATTTCGTAAGCTTTCACAGAAAGTTCGAACTCTTTGCATGCAATCATTCGCCGTCTTCTTCCACAATTGTGTTTTTTAGCCGGCGGCGGCTGGATTCGAGAAGCTTCCGATTGTTCTGTATGATCAGTCTCTCCGGACTAACCAGTTCTGTTGAAAGTGATCTCGATATGCAACAAGCGATGCTCACCAATAAAGACGAGAAGGTACTCAAAGCTTTAGAGAGAACAAGGCAATTGGATATTCCCGATGAAAAGACAATGCCAGTGCTTATGAAGCTCCTAGAAGAGGCTGGTGGCAATTGGTCGTATATAAAGTTGGATAACTATACTGCACTGGTCGACGCTATTTATTCTGTTGAGGATGAGAATAAGCAAAGTGAAGGTTCATCTAATGGTAATAGAGGGAAGAATCTTAAGGTCATTGACTCTCCTGCTACTCTGAAAAAAACTTACGAAACCCGTTCTGCATCCTCAGGTTCCTCCATTCAGGTAGTCCAGAAGCAGCCACAGCTTAGTAATGGTGATCGCAAGAGGAAATATAAAAGCAGAATTGCTGACATAACTAAAGGTTCAGAGAGCGTTAAAATCCCTCTTGTCGATGATGTTGGGAGTGAAGCTGTGCCAAAGTTTACTTACATCCCTCACAACATTGTTTACCAAAGTGCTTATCTCCACGTGTCTCTGGCTCGAATCTCTGATGAAGATTGCTGCGCAAACTGCAAAGGGAACTGTCTTTCAGCTGACTTTCCTTGCACTTGTGCTCGTGAAACCAGTGGAGAATATGCTTATACCAAAGAAGGGCTGCTAAAGGAAAAGTTTCTGGACACCTGTCTTAAGATGAAAAAGGAACCAGATTCGTTCCCTAAAGTTTACTGCAAAGACTGCCCTTTGGAGAGAGATCACGATAAGGGCACATATGGAAAATGTGATGGACACTTAATCCGAAAGTTCATCAAGGAATGCTGGAGAAAGTGTGGATGTGATATGCAGTGTGGAAATCGAGTAGTACAGAGAGGGATAAGGTGCCAACTGCAGGTTTACTTTACTCAAGAAGGGAAAGGATGGGGTCTTAGAACACTGCAAGACTTGCCCAAAGGAACCTTTATCTGTGAATACATTGGTGAAATATTGACCAACACGGAGTTATACGATCGGAATGTTAGGTCTAGTAGTGAACGACATACATATCCTGTAACTCTGGATGCAGACTGGGGTTCTGAAAAGGATCTAAAAGATGAAGAAGCTCTCTGCCTGGATGCCACAATCTGTGGAAATGTCGCAAGGTTTATCAATCACAGATGCGAGGATGCAAACATGATTGATATTCCGATAGAGATAGAGACGCCTGACAGACATTATTATCATATTGCTTTTTTTACCCTACGAGACGTGAAGGCCATGGATGAGTTGACATGGGATTACATGATAGACTTCAATGATAAAAGTCATCCTGTAAAGGCATTTAGATGTTGCTGCGGAAGCGAATCATGCAGAGACAGAAAAATAAAAGGATCTCAAGGCAAGTCTATAGAGAGAAGAAAGATTGTTTCTGCTAAAAAACAACAAGGTTCCAAAGAGGTGTCTAAAAAGCGCAAATGAGACTGGTCATTATTTAGAGTTAAACATTAAAGAAAGCATGAGCTCACAAAACACTATGATCCATCGCGAGCTCTGCATGATTCAACTAGCTTTTCCTTCTTGATGACATATACAACTTTTATGGTCTGCAGTTTTTTCTCATTTACAATCTCTTCTTTAGGTAAAAAAAAGTGTTATGTTGCCTAACCAAAGAAACTCACTGTTTAGTTCTGTTCTTCAAATTTCATGGCATATGTCAAAATAAATAAACCTTTTTTAATAGAGTTCTAGAGCGTAAAGACTGGATCGAAAAGGAGCCCATCACTGGTAAATTCAGCCAAGAGTGATCCATCGCATCAATGATTTGTAATGTTAAACAAAATTTTAATATTTAGACTTAGAAGTTGTAAT
|
| Sequence Source |
Ensembl |
| Keyword |
KW-0002--3D-structure
KW-0025--Alternative splicing
KW-0156--Chromatin regulator
KW-0158--Chromosome
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
--
|
| Interpro |
IPR007728--Pre-SET_dom
IPR001214--SET_dom
IPR025776--SUVR4/1/2
IPR018848--WIYLD_domain
|
| PROSITE |
PS50867--PRE_SET
PS51580--SAM_MT43_3
PS50280--SET
|
| Pfam |
PF05033--Pre-SET
PF00856--SET
PF10440--WIYLD
|
| Gene Ontology |
GO:0005694--C:chromosome
GO:0005730--C:nucleolus
GO:0009506--C:plasmodesma
GO:0018024--F:histone-lysine N-methyltransferase activity
GO:0008270--F:zinc ion binding
|
| Orthology |
|
| Created Date |
25-Jun-2016 |
